ModCRE DB

Transcription factor

P57073 - SOX8

Transcription factor SOX-8

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 446 aa

15 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known15
MotifPredictionSourceDNA bindingSupportLogoActions
MA0868.1 Known JASPAR AACAATGTGCAGTGTT Direct PWM Open · Scan
MA0868.2 Known JASPAR AGAACAATGG Direct PWM Open · Scan
MA0868.3 Known JASPAR AACAATG Direct PWM Open · Scan
M03483_2.00 Known CisBP AACAATGTGCAGTGTT Direct PWM Open · Scan
M03484_2.00 Known CisBP ATGAATTGCAGTC Direct PWM Open · Scan
M03485_2.00 Known CisBP GAACAATTGCAGTGTTC Direct PWM Open · Scan
M03486_2.00 Known CisBP CATCAATTGCAGTGATC Direct PWM Open · Scan
M03487_2.00 Known CisBP TGAATGTGCAGTCA Direct PWM Open · Scan
M03488_2.00 Known CisBP AACAATTGCAGTGTT Direct PWM Open · Scan
M03489_2.00 Known CisBP ATGAATTGCAGTC Direct PWM Open · Scan
M03490_2.00 Known CisBP AATCAATTGCAGTGATT Direct PWM Open · Scan
M05749_2.00 Known CisBP AGAACAATGG Direct PWM Open · Scan
M05750_2.00 Known CisBP CCATTGTTCT Direct PWM Open · Scan
M05751_2.00 Known CisBP ACAATGGGCCCATTGT Direct PWM Open · Scan
M05752_2.00 Known CisBP ACAATGGATCCATTGT Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 446 aa
100-171

Region 100-171 0 PWM

Residues
72 aa
Domains
PF00505 · HMG (high mobility group) box
3D models
1 active PDB
Templates
4EUW
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 100-1711 model
Actions
Predicted = Low TFS_P57073:100:171_4euw_A_1 4euw 100-171 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
18-89PF12444Sox developmental protein N terminalNo overlap with loaded model regions
102-170PF00505HMG (high mobility group) boxoverlaps 100-171