ModCRE DB

Transcription factor

P58317 - ZNF121

Zinc finger protein 121 (Zinc finger protein 20)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 390 aa

74 Generated PWM 7 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known3
MotifPredictionSourceDNA bindingSupportLogoActions
M08384_2.00 Known CisBP CCGGGCCAAGGCAGCGAGACCCCA Direct PWM Open · Scan
M08951_2.00 Known CisBP GGTCTTGCTATGTTGCCCAG Direct PWM Open · Scan
ZN121_HUMAN.H11MO.0.C Known HOCOMOCO CTGGGCAACATAGCAAGACC Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)69
MotifPredictionSourceDNA bindingSupportLogoActions
M00939_2.00 NN 70-40% CisBP CCACCTCA 67.8% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 64.7% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 62.3% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 61.9% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 61.1% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 61.1% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 60.7% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 60.3% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 60.0% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 60.0% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 59.5% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 59.5% identity Open · Scan
M08335_2.00 NN 70-40% CisBP AGTCGTTGTCTG 59.1% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 58.8% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 57.8% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 57.4% identity Open · Scan
M07678_2.00 NN 70-40% CisBP CCCGCCCCCTCCTCCCCCTTCCCACCC 57.4% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 57.3% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 57.1% identity Open · Scan
M07689_2.00 NN 70-40% CisBP ACCCAGGCTCCTTCCATCTTGTGGCTC 57.0% identity Open · Scan
M08917_2.00 NN 70-40% CisBP GCTGAGCCATGTGGGGTGCT 56.9% identity Open · Scan
M04613_2.00 NN 70-40% CisBP CTCATGTGCTAATTACAAA 56.5% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 56.1% identity Open · Scan
M07707_2.00 NN 70-40% CisBP TCCCGC 55.7% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 55.7% identity Open · Scan
M07699_2.00 NN 70-40% CisBP GGTTTAT 55.6% identity Open · Scan
M06108_2.00 NN 70-40% CisBP ACAACAACAAC 55.5% identity Open · Scan
M08254_2.00 NN 70-40% CisBP CTGCCCTGGGACTTT 55.3% identity Open · Scan
M08255_2.00 NN 70-40% CisBP CTCTTCCGGT 55.3% identity Open · Scan
M08985_2.00 NN 70-40% CisBP TGAGGACCTACTGTGTGCC 54.9% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 54.5% identity Open · Scan
M00134_2.00 NN 70-40% CisBP GCCACGCCCA 54.2% identity Open · Scan
M08309_2.00 NN 70-40% CisBP AAAAACCCCCCTGCAGAGCCCAGCCCT 53.6% identity Open · Scan
M08934_2.00 NN 70-40% CisBP GCTGTACCTGCTTATTAGGC 53.6% identity Open · Scan
M07686_2.00 NN 70-40% CisBP TAGCTTGTTTCCAGCCAC 53.4% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 53.0% identity Open · Scan
M07635_2.00 NN 70-40% CisBP AAGTTTTCTTGTATTATATCT 52.8% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 52.7% identity Open · Scan
M07700_2.00 NN 70-40% CisBP ATGTTGTGAGGAAGCCCA 52.6% identity Open · Scan
M08334_2.00 NN 70-40% CisBP TTTGTTTTTTTCTGATTGCTTTTTACTTAT 52.4% identity Open · Scan
M04505_2.00 NN 70-40% CisBP AGCTTTTCCCACAC 52.3% identity Open · Scan
M07567_2.00 NN 70-40% CisBP CCACTCCACTCA 52.2% identity Open · Scan
M08347_2.00 NN 70-40% CisBP GCCCTGGGCAGC 51.9% identity Open · Scan
M08367_2.00 NN 70-40% CisBP GGGGTGATGACCACTCTGGCTTCTTAC 51.9% identity Open · Scan
M08342_2.00 NN 70-40% CisBP GCTCTGCCTCCCTCT 51.6% identity Open · Scan
M04621_2.00 NN 70-40% CisBP AGCAATTCCGCTCA 51.5% identity Open · Scan
M08392_2.00 NN 70-40% CisBP CTTCACCTGCTGAGG 51.5% identity Open · Scan
MA1589.1 NN 70-40% JASPAR TAGGAGTGGAATTGCTGGGTC 51.5% identity Open · Scan
MA1602.1 NN 70-40% JASPAR CGTCTACACGGG 51.5% identity Open · Scan
M08267_2.00 NN 70-40% CisBP CAGTTTCATTTTCC 51.1% identity Open · Scan
M08371_2.00 NN 70-40% CisBP CCAGACTTGTCCTCT 51.1% identity Open · Scan
M07649_2.00 NN 70-40% CisBP CCCCCCCCCCCCTCAGGAATGCC 51.0% identity Open · Scan
M01039_2.00 NN 70-40% CisBP CCCCCTA 50.9% identity Open · Scan
M05853_2.00 NN 70-40% CisBP CCACCTTTAGCCATATCT 50.9% identity Open · Scan
MA1587.1 NN 70-40% JASPAR CCTCGACCTCCTGA 50.9% identity Open · Scan
M08256_2.00 NN 70-40% CisBP GTGCCTT 50.7% identity Open · Scan
M08252_2.00 NN 70-40% CisBP CCGGCTCCAGCACCC 50.6% identity Open · Scan
M00609_2.00 NN 70-40% CisBP GGAAGCCCTA 50.4% identity Open · Scan
MA1154.1 NN 70-40% JASPAR CTTTCCCACAACACGAC 50.3% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 50.1% identity Open · Scan
M08395_2.00 NN 70-40% CisBP GCTGCCTACTCTTCC 50.1% identity Open · Scan
M00224_2.00 NN 70-40% CisBP CCCGCCCC 50.0% identity Open · Scan
M02903_2.00 NN 70-40% CisBP ATGCCACGCCCCTTTTTG 50.0% identity Open · Scan
M04463_2.00 NN 70-40% CisBP CACCACGCCCA 50.0% identity Open · Scan
M07601_2.00 NN 70-40% CisBP CAGATGCCGGCACCATGCTTC 50.0% identity Open · Scan
M08908_2.00 NN 70-40% CisBP GCTGCTGCTTCTGCTG 50.0% identity Open · Scan
MA0039.1 NN 70-40% JASPAR TAAAGGAAGG 50.0% identity Open · Scan
MA0039.3 NN 70-40% JASPAR CCACACCCTGC 50.0% identity Open · Scan
MA1515.1 NN 70-40% JASPAR CACCACGCCCA 50.0% identity Open · Scan
ModCRE2
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_P58317_ZN121_HUMAN:310:358_1llm_D_1 ModCRE Homology model CTATCGCCGAAA Region 310-358 · 1 3D model Open · Scan
TFS_sp_P58317_ZN121_HUMAN:141:251_5ei9_E_1 ModCRE Homology model GGGGGGGGGGGGGGCCC Region 141-251 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 390 aa
113-390

Region 113-390 2 PWM

Residues
278 aa
Domains
PF13465 · Zinc-finger double domain PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
7 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
7 active PDB models 6 summary rows
Region 113-3907 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_P58317_ZN121_HUMAN:310:358_1llm_D_1 1llm 310-358 View model · PDB
Predicted = Low TFS_sp_P58317_ZN121_HUMAN:113:390_5wjq_D_1 5wjq 113-390 View model · PDB
Predicted = Low TFS_sp_P58317_ZN121_HUMAN:119:390_5v3j_E_1 5v3j 119-390 View model · PDB
Predicted = Low TFS_sp_P58317_ZN121_HUMAN:119:390_5v3m_C_1 5v3m 119-390 View model · PDB
Predicted = Low TFS_sp_P58317_ZN121_HUMAN:135:390_7w1m_H_1 7w1m 135-390 View model · PDB
Predicted = Low TFS_sp_P58317_ZN121_HUMAN:141:251_5ei9_E_1 5ei9 141-251 View model · PDB
Predicted = Low TFS_sp_P58317_ZN121_HUMAN:181:334_2i13_A_1 2i13 181-334 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 2i13 113:390 181 334 P:A · DNA:C,D 53.2% / 68.8% 100 View · PDB TFS_sp_P58317_ZN121_HUMAN:181:334_2i13_A_1
2 5v3m 113:390 119 390 P:C · DNA:A,B 50.4% / 65.8% 98 View · PDB TFS_sp_P58317_ZN121_HUMAN:119:390_5v3m_C_1
3 5v3j 113:390 119 390 P:E · DNA:A,B 50.4% / 65.8% 98 View · PDB TFS_sp_P58317_ZN121_HUMAN:119:390_5v3j_E_1
1 5wjq 113:390 113 390 P:D · DNA:A,B 50.0% / 66.5% 98 View · PDB TFS_sp_P58317_ZN121_HUMAN:113:390_5wjq_D_1
1 1llm 113:390 310,310 358,358 P:C,D · DNA:A,B 46.9% / 65.3% 56,57 View · PDB DIMER_sp_P58317_ZN121_HUMAN:310:358_1llm_D_1
5 7w1m 113:390 135 390 P:H · DNA:F,G 37.9% / 54.4% 79 View · PDB TFS_sp_P58317_ZN121_HUMAN:135:390_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
158-182PF13465Zinc-finger double domainoverlaps 113-390
200-222PF00096Zinc finger, C2H2 typeoverlaps 113-390
228-250PF00096Zinc finger, C2H2 typeoverlaps 113-390
256-278PF00096Zinc finger, C2H2 typeoverlaps 113-390
284-306PF00096Zinc finger, C2H2 typeoverlaps 113-390
312-334PF00096Zinc finger, C2H2 typeoverlaps 113-390
340-362PF00096Zinc finger, C2H2 typeoverlaps 113-390
368-390PF00096Zinc finger, C2H2 typeoverlaps 113-390