ModCRE DB

Transcription factor

Q00653 - NFKB2

Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10 protein) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2) (Oncogene Lyt-10) (Lyt10) [Cleaved into: Nuclear factor NF-kappa-B p52 subunit]

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 900 aa

7 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known7
MotifPredictionSourceDNA bindingSupportLogoActions
MA0778.1 Known JASPAR AGGGGATTCCCCT Direct PWM Open · Scan
MA0778.2 Known JASPAR GGGGATTCCCC Direct PWM Open · Scan
M03446_2.00 Known CisBP AGGGGATTCCCCT Direct PWM Open · Scan
M05699_2.00 Known CisBP CGGTGCTTCCCCT Direct PWM Open · Scan
M05700_2.00 Known CisBP AGGTGCTTCCCCT Direct PWM Open · Scan
M09344_2.00 Known CisBP GGGGCTTTCCC Direct PWM Open · Scan
NFKB2_HUMAN.H11MO.0.B Known HOCOMOCO GGGAAAGCCCC Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 900 aa
37-327

Region 37-327 0 PWM

Residues
291 aa
Domains
PF00554 · Rel homology DNA-binding domain PF16179 · Rel homology dimerisation domain
3D models
1 active PDB
Templates
1A3Q
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 37-3271 model
Actions
Predicted = Low DIMER_Q00653:37:327_1a3q_B_1 1a3q 37-327 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
40-220PF00554Rel homology DNA-binding domainoverlaps 37-327
229-327PF16179Rel homology dimerisation domainoverlaps 37-327
487-508PF00023Ankyrin repeatNo overlap with loaded model regions
520-586PF12796Ankyrin repeats (3 copies)No overlap with loaded model regions
605-697PF12796Ankyrin repeats (3 copies)No overlap with loaded model regions
776-848PF00531Death domainNo overlap with loaded model regions