ModCRE DB

Transcription factor

Q01196 - RUNX1

Runt-related transcription factor 1 (Acute myeloid leukemia 1 protein) (Core-binding factor subunit alpha-2) (CBF-alpha-2) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEA2-alpha B) (PEBP2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 453 aa

8 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known8
MotifPredictionSourceDNA bindingSupportLogoActions
MA0002.1 Known JASPAR TATTGTGGTTA Direct PWM Open · Scan
MA0002.2 Known JASPAR GTCTGTGGTTT Direct PWM Open · Scan
MA0002.3 Known JASPAR CTGTGGTTT Direct PWM Open · Scan
M09371_2.00 Known CisBP GAAACCACAGA Direct PWM Open · Scan
M09631_2.00 Known CisBP ACCACATCCTGT Direct PWM Open · Scan
M09632_2.00 Known CisBP AAACCACAAA Direct PWM Open · Scan
M11258_2.00 Known CisBP ACCACA Direct PWM Open · Scan
RUNX1_HUMAN.H11MO.0.A Known HOCOMOCO TCTGTGGTTTC Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 453 aa
50-177

Region 50-177 0 PWM

Residues
128 aa
Domains
PF00853 · Runt domain
3D models
1 active PDB
Templates
4L0Y
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 50-1771 model
Actions
Predicted = Low TFS_Q01196:50:177_4l0y_A_1 4l0y 50-177 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
52-179PF00853Runt domainoverlaps 50-177
362-453PF08504Runx inhibition domainNo overlap with loaded model regions