ModCRE DB

Transcription factor

Q03112 - MECOM

Histone-lysine N-methyltransferase MECOM (EC 2.1.1.367) (Ecotropic virus integration site 1 protein homolog) (EVI-1) (MDS1 and EVI1 complex locus protein) (Myelodysplasia syndrome 1 protein) (Myelodysplasia syndrome-associated protein 1)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 1230 aa

8 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known8
MotifPredictionSourceDNA bindingSupportLogoActions
M08862_2.00 Known CisBP TATCTTATCTTATCTT Direct PWM Open · Scan
M10125_2.00 Known CisBP TTATCTTATCTTATCT Direct PWM Open · Scan
M10126_2.00 Known CisBP TTATCTTATCT Direct PWM Open · Scan
M10127_2.00 Known CisBP TTATCTTATCT Direct PWM Open · Scan
M10128_2.00 Known CisBP TATCTTATCATATCC Direct PWM Open · Scan
M10129_2.00 Known CisBP TTATCTTATCT Direct PWM Open · Scan
M10130_2.00 Known CisBP TTATCTTGT Direct PWM Open · Scan
EVI1_HUMAN.H11MO.0.B Known HOCOMOCO AAGATAAGATAAGATA Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 1230 aa
206-429

Region 206-429 0 PWM

Residues
224 aa
Domains
PF13912 · C2H2-type zinc finger PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
1 active PDB
Templates
5WJQ
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 206-4291 model
Actions
Predicted = Low TFS_Q03112:206:429_5wjq_D_1 5wjq 206-429 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
81-199PF21549PR domain zinc finger protein 2, PR domainNo overlap with loaded model regions
264-286PF13912C2H2-type zinc fingeroverlaps 206-429
291-313PF00096Zinc finger, C2H2 typeoverlaps 206-429
319-342PF00096Zinc finger, C2H2 typeoverlaps 206-429
348-370PF00096Zinc finger, C2H2 typeoverlaps 206-429
376-398PF00096Zinc finger, C2H2 typeoverlaps 206-429
406-425PF00096Zinc finger, C2H2 typeoverlaps 206-429
912-934PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
940-963PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
969-991PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions