ModCRE DB

Transcription factor

Q05925 - EN1

Homeobox protein engrailed-1 (Homeobox protein en-1) (Hu-En-1)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 392 aa

11 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known11
MotifPredictionSourceDNA bindingSupportLogoActions
MA0027.2 Known JASPAR CTAATTAG Direct PWM Open · Scan
MA0027.3 Known JASPAR TAATTA Direct PWM Open · Scan
M03180_2.00 Known CisBP GCTAATTGGG Direct PWM Open · Scan
M03181_2.00 Known CisBP TAATTGGTCAATTA Direct PWM Open · Scan
M03182_2.00 Known CisBP CTAATTAG Direct PWM Open · Scan
M03183_2.00 Known CisBP TAATTGCTTAATTA Direct PWM Open · Scan
M05218_2.00 Known CisBP CTAATTGC Direct PWM Open · Scan
M05219_2.00 Known CisBP CTAACGAG Direct PWM Open · Scan
M05220_2.00 Known CisBP CTAATTGG Direct PWM Open · Scan
M05871_2.00 Known CisBP ACTAATTA Direct PWM Open · Scan
M10714_2.00 Known CisBP GTAATTG Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 392 aa
304-359

Region 304-359 0 PWM

Residues
56 aa
Domains
PF00046 · Homeodomain
3D models
1 active PDB
Templates
2HDD
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 304-3591 model
Actions
Predicted = Low DIMER_Q05925:304:359_2hdd_B_1 2hdd 304-359 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
304-360PF00046Homeodomainoverlaps 304-359
361-390PF10525Engrailed homeobox C-terminal signature domainNo overlap with loaded model regions