Transcription factor

Q05BY5 - ZNF282

ZNF282 protein

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 298 aa

110 Generated PWM 6 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)104

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M07712_2.00	NN 70-40%	CisBP	ACATTTTTTTAATCTAAAAAAACATTTACA	60.1% identity		Open · Scan
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	59.0% identity		Open · Scan
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	59.0% identity		Open · Scan
M08279_2.00	NN 70-40%	CisBP	CCTCCCTCC	58.9% identity		Open · Scan
M07601_2.00	NN 70-40%	CisBP	CAGATGCCGGCACCATGCTTC	58.6% identity		Open · Scan
M07656_2.00	NN 70-40%	CisBP	TGTCTAGTAAGTCTA	57.9% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	57.8% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	57.6% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	57.6% identity		Open · Scan
M08234_2.00	NN 70-40%	CisBP	GTCAACTTGACTGGGCCA	57.2% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	57.1% identity		Open · Scan
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	56.4% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	56.4% identity		Open · Scan
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	56.4% identity		Open · Scan
M07660_2.00	NN 70-40%	CisBP	CCGCGCCTACCTGAGGGCGCGGGCCTGGGG	56.1% identity		Open · Scan
M08245_2.00	NN 70-40%	CisBP	TGGTGCCTTATTCCC	55.3% identity		Open · Scan
M07587_2.00	NN 70-40%	CisBP	CCCCCTCCCCAGTCGAGCCCCCGC	55.0% identity		Open · Scan
M07691_2.00	NN 70-40%	CisBP	CCTGCAGCCACCTTGGCCTTG	55.0% identity		Open · Scan
M07581_2.00	NN 70-40%	CisBP	TCCCCTGTGCTTCTCTCCCCT	54.6% identity		Open · Scan
M08300_2.00	NN 70-40%	CisBP	CTGCCCAATTCAT	54.4% identity		Open · Scan
M08311_2.00	NN 70-40%	CisBP	CTGGAACAGAAGGGGCGA	54.3% identity		Open · Scan
M07567_2.00	NN 70-40%	CisBP	CCACTCCACTCA	54.0% identity		Open · Scan
M07600_2.00	NN 70-40%	CisBP	GCATTAGC	54.0% identity		Open · Scan
M07725_2.00	NN 70-40%	CisBP	AAGCACTGTACT	54.0% identity		Open · Scan
M00774_2.00	NN 70-40%	CisBP	TTAGTATACACAAGT	53.9% identity		Open · Scan
M07613_2.00	NN 70-40%	CisBP	TCACTCAGTCATTCA	53.9% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	53.9% identity		Open · Scan
M08373_2.00	NN 70-40%	CisBP	CCCCCTGGCTCTTCCTCT	53.9% identity		Open · Scan
M07633_2.00	NN 70-40%	CisBP	CTCTCGTTGTGCCTTTGCCAT	53.6% identity		Open · Scan
M07777_2.00	NN 70-40%	CisBP	GCCAATTTCCGTGGTGTAAAT	53.6% identity		Open · Scan
M07588_2.00	NN 70-40%	CisBP	TCCTTCCCTCTTTCC	53.5% identity		Open · Scan
M07635_2.00	NN 70-40%	CisBP	AAGTTTTCTTGTATTATATCT	53.2% identity		Open · Scan
M07658_2.00	NN 70-40%	CisBP	CCGCCGCAGCCGCCG	53.2% identity		Open · Scan
M07754_2.00	NN 70-40%	CisBP	CGCCCCCTCCCT	53.2% identity		Open · Scan
M08291_2.00	NN 70-40%	CisBP	AATCCAGCCCTAGACTCTCCC	53.2% identity		Open · Scan
M08292_2.00	NN 70-40%	CisBP	TGTATTCCTTGTCATGTGTGG	53.2% identity		Open · Scan
M08320_2.00	NN 70-40%	CisBP	TTCCCTGCC	53.2% identity		Open · Scan
M08371_2.00	NN 70-40%	CisBP	CCAGACTTGTCCTCT	53.2% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	53.2% identity		Open · Scan
MA1656.1	NN 70-40%	JASPAR	CCAAGCCCAACCAG	53.2% identity		Open · Scan
M00764_2.00	NN 70-40%	CisBP	GTCTACAC	53.1% identity		Open · Scan
M10303_2.00	NN 70-40%	CisBP	TACTGGGAATACC	53.0% identity		Open · Scan
MA0056.1	NN 70-40%	JASPAR	TGGGGA	52.9% identity		Open · Scan
MA1154.1	NN 70-40%	JASPAR	CTTTCCCACAACACGAC	52.8% identity		Open · Scan
MA1587.1	NN 70-40%	JASPAR	CCTCGACCTCCTGA	52.8% identity		Open · Scan
M08358_2.00	NN 70-40%	CisBP	CCCTCCCCCTCC	52.7% identity		Open · Scan
M00782_2.00	NN 70-40%	CisBP	AGTGTGCGCTA	52.5% identity		Open · Scan
M04650_2.00	NN 70-40%	CisBP	GCATAACTGCCCCGCTGCC	52.5% identity		Open · Scan
M05853_2.00	NN 70-40%	CisBP	CCACCTTTAGCCATATCT	52.5% identity		Open · Scan
M07638_2.00	NN 70-40%	CisBP	TGCAGCTCCCTGCCC	52.5% identity		Open · Scan
M07700_2.00	NN 70-40%	CisBP	ATGTTGTGAGGAAGCCCA	52.5% identity		Open · Scan
M08263_2.00	NN 70-40%	CisBP	ATCTCGGCACTTTGGGAGGCCA	52.5% identity		Open · Scan
M08274_2.00	NN 70-40%	CisBP	TTACTTGCAGCCCAACGCATTCCTAAC	52.5% identity		Open · Scan
M08314_2.00	NN 70-40%	CisBP	ATTCATCAAGGTCCTCAACAATGG	52.5% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	52.5% identity		Open · Scan
M08355_2.00	NN 70-40%	CisBP	GCGAACTCCTATTCATCC	52.5% identity		Open · Scan
M08357_2.00	NN 70-40%	CisBP	GAGCCTGCTACTGAGCCTGGG	52.5% identity		Open · Scan
M08392_2.00	NN 70-40%	CisBP	CTTCACCTGCTGAGG	52.5% identity		Open · Scan
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	52.3% identity		Open · Scan
M08908_2.00	NN 70-40%	CisBP	GCTGCTGCTTCTGCTG	52.3% identity		Open · Scan
M04613_2.00	NN 70-40%	CisBP	CTCATGTGCTAATTACAAA	52.2% identity		Open · Scan
M07593_2.00	NN 70-40%	CisBP	AGATGAAGTCACCCCTCTTAC	52.1% identity		Open · Scan
M07595_2.00	NN 70-40%	CisBP	GCCTGTTCCTCTCCC	52.1% identity		Open · Scan
M07618_2.00	NN 70-40%	CisBP	CCTTTGGTGCTC	52.1% identity		Open · Scan
M07701_2.00	NN 70-40%	CisBP	CCTGGGCTAGGCCCTGGC	52.1% identity		Open · Scan
M01883_2.00	NN 70-40%	CisBP	TGCCCCTGA	52.0% identity		Open · Scan
M07590_2.00	NN 70-40%	CisBP	TTTTTTTCTTTTATTTTTTTTTTTTTTTTTTTT	51.8% identity		Open · Scan
M07610_2.00	NN 70-40%	CisBP	CCTTCTTCCTCCCCCCTGCCCACC	51.7% identity		Open · Scan
M07662_2.00	NN 70-40%	CisBP	CCTGTGTCCTCCCTGGTCCCC	51.7% identity		Open · Scan
M07688_2.00	NN 70-40%	CisBP	GAGCCCCAAGCA	51.7% identity		Open · Scan
M07764_2.00	NN 70-40%	CisBP	CTGCACTCTCCCCTTCCCCCCCTCCCC	51.7% identity		Open · Scan
M08347_2.00	NN 70-40%	CisBP	GCCCTGGGCAGC	51.7% identity		Open · Scan
M08395_2.00	NN 70-40%	CisBP	GCTGCCTACTCTTCC	51.7% identity		Open · Scan
M08917_2.00	NN 70-40%	CisBP	GCTGAGCCATGTGGGGTGCT	51.7% identity		Open · Scan
M08944_2.00	NN 70-40%	CisBP	TACCATGCTGTTTTGATTAC	51.7% identity		Open · Scan
M08949_2.00	NN 70-40%	CisBP	TTCTATTTCTTCTTGTGTCA	51.7% identity		Open · Scan
MA0130.1	NN 70-40%	JASPAR	ATCCAC	51.7% identity		Open · Scan
M08247_2.00	NN 70-40%	CisBP	AAAAATAACAAACGG	51.3% identity		Open · Scan
MA1594.1	NN 70-40%	JASPAR	AGGGGACATCACTACAGATCCCAC	51.3% identity		Open · Scan
MA1652.1	NN 70-40%	JASPAR	GGAGGAGGTGAGAA	51.2% identity		Open · Scan
M01042_2.00	NN 70-40%	CisBP	TGGGACCTGA	51.1% identity		Open · Scan
M01538_2.00	NN 70-40%	CisBP	GCCCCTGA	51.1% identity		Open · Scan
M07598_2.00	NN 70-40%	CisBP	CTGACAATACCAAGTGTTGAC	51.0% identity		Open · Scan
M07605_2.00	NN 70-40%	CisBP	TATTTTTTTTTATTTTTTTTTTTTTTTTTT	51.0% identity		Open · Scan
M07667_2.00	NN 70-40%	CisBP	CCGCACAGGCCCCCGGGCCCC	51.0% identity		Open · Scan
M07686_2.00	NN 70-40%	CisBP	TAGCTTGTTTCCAGCCAC	51.0% identity		Open · Scan
M07689_2.00	NN 70-40%	CisBP	ACCCAGGCTCCTTCCATCTTGTGGCTC	51.0% identity		Open · Scan
M08914_2.00	NN 70-40%	CisBP	ATTTAGTCCATTTACATTTAATGT	51.0% identity		Open · Scan
M04621_2.00	NN 70-40%	CisBP	AGCAATTCCGCTCA	50.7% identity		Open · Scan
M07723_2.00	NN 70-40%	CisBP	CCGCTGCTCCCTGCT	50.7% identity		Open · Scan
MA1589.1	NN 70-40%	JASPAR	TAGGAGTGGAATTGCTGGGTC	50.7% identity		Open · Scan
M07579_2.00	NN 70-40%	CisBP	CATCTCCAGGA	50.3% identity		Open · Scan
M07646_2.00	NN 70-40%	CisBP	CTTTTTTTT	50.3% identity		Open · Scan
M07678_2.00	NN 70-40%	CisBP	CCCGCCCCCTCCTCCCCCTTCCCACCC	50.3% identity		Open · Scan
M08309_2.00	NN 70-40%	CisBP	AAAAACCCCCCTGCAGAGCCCAGCCCT	50.3% identity		Open · Scan
M08330_2.00	NN 70-40%	CisBP	TGGGTGCCGGACTGCTGTTCC	50.3% identity		Open · Scan
M08335_2.00	NN 70-40%	CisBP	AGTCGTTGTCTG	50.3% identity		Open · Scan
M08399_2.00	NN 70-40%	CisBP	TACTCTGGGGCCACATGACTC	50.3% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	50.0% identity		Open · Scan
M04465_2.00	NN 70-40%	CisBP	GTGATTCTTATCTTATCCTT	50.0% identity		Open · Scan
M07562_2.00	NN 70-40%	CisBP	GAAAAAAAC	50.0% identity		Open · Scan
M08283_2.00	NN 70-40%	CisBP	GACTTTTATTTT	50.0% identity		Open · Scan
MA1597.1	NN 70-40%	JASPAR	CCCAGGGAAGCCATTTC	50.0% identity		Open · Scan
MA1602.1	NN 70-40%	JASPAR	CGTCTACACGGG	50.0% identity		Open · Scan

ModCRE6

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
DIMER_tr_Q05BY5_Q05BY5_HUMAN:199:250_1llm_C_1	ModCRE	Homology model	GTGCGCGCCGGA	Region 199-250 · 1 3D model		Open · Scan
TFS_tr_Q05BY5_Q05BY5_HUMAN:142:281_5v3j_E_1	ModCRE	Homology model	TATCCCCAACCGGGGGGGCTTAT	Region 142-281 · 1 3D model		Open · Scan
TFS_tr_Q05BY5_Q05BY5_HUMAN:142:281_5v3m_C_1	ModCRE	Homology model	CATATTCCCTCCCCCCCCCCCCT	Region 142-281 · 1 3D model		Open · Scan
TFS_tr_Q05BY5_Q05BY5_HUMAN:143:279_2i13_A_1	ModCRE	Homology model	ACCCTAGCAGCACTACTGCCA	Region 143-279 · 1 3D model		Open · Scan
TFS_tr_Q05BY5_Q05BY5_HUMAN:144:280_5wjq_D_1	ModCRE	Homology model	ACCGTGCCCCCCCTGGGCCA	Region 144-280 · 1 3D model		Open · Scan
TFS_tr_Q05BY5_Q05BY5_HUMAN:170:280_5ei9_E_1	ModCRE	Homology model	GGGGCCGGCCCCGGGGA	Region 170-280 · 1 3D model		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 298 aa

142-281

Region 142-281 6 PWM

Residues

140 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

6 active PDBs · 6 summary rows

Templates

1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

6 active PDB models 6 summary rows

Region 142-2816 models · 6 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_tr_Q05BY5_Q05BY5_HUMAN:199:250_1llm_C_1	1llm	199-250	View model · PDB
Predicted = Low	TFS_tr_Q05BY5_Q05BY5_HUMAN:142:281_5v3j_E_1	5v3j	142-281	View model · PDB
Predicted = Low	TFS_tr_Q05BY5_Q05BY5_HUMAN:142:281_5v3m_C_1	5v3m	142-281	View model · PDB
Predicted = Low	TFS_tr_Q05BY5_Q05BY5_HUMAN:143:279_2i13_A_1	2i13	143-279	View model · PDB
Predicted = Low	TFS_tr_Q05BY5_Q05BY5_HUMAN:144:280_5wjq_D_1	5wjq	144-280	View model · PDB
Predicted = Low	TFS_tr_Q05BY5_Q05BY5_HUMAN:170:280_5ei9_E_1	5ei9	170-280	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
1	2i13	141:281	143	279	P:A · DNA:C,D	56.9% / 71.5%	90	View · PDB TFS_tr_Q05BY5_Q05BY5_HUMAN:143:279_2i13_A_1
5	5ei9	141:281	170	280	P:E · DNA:A,B	53.2% / 64.9%	100	View · PDB TFS_tr_Q05BY5_Q05BY5_HUMAN:170:280_5ei9_E_1
2	5wjq	141:281	144	280	P:D · DNA:A,B	48.2% / 65.7%	48	View · PDB TFS_tr_Q05BY5_Q05BY5_HUMAN:144:280_5wjq_D_1
3	5v3m	141:281	142	281	P:C · DNA:A,B	46.4% / 61.4%	50	View · PDB TFS_tr_Q05BY5_Q05BY5_HUMAN:142:281_5v3m_C_1
4	5v3j	141:281	142	281	P:E · DNA:A,B	46.4% / 61.4%	50	View · PDB TFS_tr_Q05BY5_Q05BY5_HUMAN:142:281_5v3j_E_1
1	1llm	141:281	199,199	250,250	P:C,D · DNA:A,B	42.3% / 63.5%	59,61	View · PDB DIMER_tr_Q05BY5_Q05BY5_HUMAN:199:250_1llm_C_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
87-128	PF01352	KRAB box	No overlap with loaded model regions
145-167	PF00096	Zinc finger, C2H2 type	overlaps 142-281
173-195	PF00096	Zinc finger, C2H2 type	overlaps 142-281
201-223	PF00096	Zinc finger, C2H2 type	overlaps 142-281
229-251	PF00096	Zinc finger, C2H2 type	overlaps 142-281
257-279	PF00096	Zinc finger, C2H2 type	overlaps 142-281