Transcription factor

Q08AN1 - ZNF616

Zinc finger protein 616

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 781 aa

92 Generated PWM 7 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known1

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M07755_2.00	Known	CisBP	TCACGCTCACCCACT	Direct PWM		Open · Scan

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)90

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M00955_2.00	NN 70-40%	CisBP	ACGTCCTCT	69.4% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	68.2% identity		Open · Scan
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	68.2% identity		Open · Scan
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	67.0% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	67.0% identity		Open · Scan
MA1124.1	NN 70-40%	JASPAR	CATTCATTCATTC	66.0% identity		Open · Scan
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	65.8% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	65.8% identity		Open · Scan
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	64.7% identity		Open · Scan
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	64.7% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	64.7% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	64.7% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	62.8% identity		Open · Scan
M04650_2.00	NN 70-40%	CisBP	GCATAACTGCCCCGCTGCC	62.4% identity		Open · Scan
M08985_2.00	NN 70-40%	CisBP	TGAGGACCTACTGTGTGCC	61.6% identity		Open · Scan
M07613_2.00	NN 70-40%	CisBP	TCACTCAGTCATTCA	61.5% identity		Open · Scan
M07689_2.00	NN 70-40%	CisBP	ACCCAGGCTCCTTCCATCTTGTGGCTC	59.8% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	59.7% identity		Open · Scan
M04465_2.00	NN 70-40%	CisBP	GTGATTCTTATCTTATCCTT	59.2% identity		Open · Scan
M00782_2.00	NN 70-40%	CisBP	AGTGTGCGCTA	58.6% identity		Open · Scan
M04613_2.00	NN 70-40%	CisBP	CTCATGTGCTAATTACAAA	58.6% identity		Open · Scan
M07700_2.00	NN 70-40%	CisBP	ATGTTGTGAGGAAGCCCA	58.6% identity		Open · Scan
M08355_2.00	NN 70-40%	CisBP	GCGAACTCCTATTCATCC	58.6% identity		Open · Scan
M08887_2.00	NN 70-40%	CisBP	CCTCCTCCAGGAAGCCTTCCCTGA	57.6% identity		Open · Scan
M08267_2.00	NN 70-40%	CisBP	CAGTTTCATTTTCC	57.0% identity		Open · Scan
M04611_2.00	NN 70-40%	CisBP	CTTTCGGACAC	56.8% identity		Open · Scan
MA1599.1	NN 70-40%	JASPAR	CGGGCCAAGCCCCTAT	56.8% identity		Open · Scan
M04387_2.00	NN 70-40%	CisBP	CGTGCTCCCC	56.7% identity		Open · Scan
M07753_2.00	NN 70-40%	CisBP	TGCATTCCTTGGCTTGTG	56.5% identity		Open · Scan
M08252_2.00	NN 70-40%	CisBP	CCGGCTCCAGCACCC	56.4% identity		Open · Scan
M07582_2.00	NN 70-40%	CisBP	TCCCTG	56.2% identity		Open · Scan
M08347_2.00	NN 70-40%	CisBP	GCCCTGGGCAGC	56.1% identity		Open · Scan
M04621_2.00	NN 70-40%	CisBP	AGCAATTCCGCTCA	56.0% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	56.0% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	55.9% identity		Open · Scan
M07578_2.00	NN 70-40%	CisBP	CAACTCTCC	55.8% identity		Open · Scan
M07686_2.00	NN 70-40%	CisBP	TAGCTTGTTTCCAGCCAC	55.8% identity		Open · Scan
M08371_2.00	NN 70-40%	CisBP	CCAGACTTGTCCTCT	55.8% identity		Open · Scan
M00134_2.00	NN 70-40%	CisBP	GCCACGCCCA	55.7% identity		Open · Scan
M06179_2.00	NN 70-40%	CisBP	TAAGCCTATAGA	55.5% identity		Open · Scan
M08325_2.00	NN 70-40%	CisBP	TTTTTTTTT	55.4% identity		Open · Scan
M07657_2.00	NN 70-40%	CisBP	CCCCTGCATGTCCCCATTTTT	55.3% identity		Open · Scan
M00786_2.00	NN 70-40%	CisBP	TATATATAT	54.9% identity		Open · Scan
M04536_2.00	NN 70-40%	CisBP	ACGTAACCCGATACC	54.9% identity		Open · Scan
M07620_2.00	NN 70-40%	CisBP	TTGGATCTGTGGATTCATGTCTTTCAT	54.9% identity		Open · Scan
M08274_2.00	NN 70-40%	CisBP	TTACTTGCAGCCCAACGCATTCCTAAC	54.9% identity		Open · Scan
M08860_2.00	NN 70-40%	CisBP	TCTTATAAGGGCACTAATCCCATT	54.7% identity		Open · Scan
M07685_2.00	NN 70-40%	CisBP	CTTTCCAGCCAC	54.6% identity		Open · Scan
M07586_2.00	NN 70-40%	CisBP	GGGACCCGGGTGGGGGCGTCCCCC	54.5% identity		Open · Scan
M07767_2.00	NN 70-40%	CisBP	AAAAACCCCAGA	54.5% identity		Open · Scan
M04598_2.00	NN 70-40%	CisBP	CGCTAACTCTCCACA	53.9% identity		Open · Scan
M08309_2.00	NN 70-40%	CisBP	AAAAACCCCCCTGCAGAGCCCAGCCCT	53.9% identity		Open · Scan
M08311_2.00	NN 70-40%	CisBP	CTGGAACAGAAGGGGCGA	53.9% identity		Open · Scan
M07566_2.00	NN 70-40%	CisBP	TCAAACCATCCTTGC	53.8% identity		Open · Scan
M08254_2.00	NN 70-40%	CisBP	CTGCCCTGGGACTTT	53.8% identity		Open · Scan
MA1602.1	NN 70-40%	JASPAR	CGTCTACACGGG	53.8% identity		Open · Scan
M08314_2.00	NN 70-40%	CisBP	ATTCATCAAGGTCCTCAACAATGG	53.7% identity		Open · Scan
M07600_2.00	NN 70-40%	CisBP	GCATTAGC	53.3% identity		Open · Scan
M07649_2.00	NN 70-40%	CisBP	CCCCCCCCCCCCTCAGGAATGCC	53.3% identity		Open · Scan
M00609_2.00	NN 70-40%	CisBP	GGAAGCCCTA	53.2% identity		Open · Scan
M07562_2.00	NN 70-40%	CisBP	GAAAAAAAC	53.1% identity		Open · Scan
M08540_2.00	NN 70-40%	CisBP	CCCCT	53.0% identity		Open · Scan
M08395_2.00	NN 70-40%	CisBP	GCTGCCTACTCTTCC	52.5% identity		Open · Scan
M08917_2.00	NN 70-40%	CisBP	GCTGAGCCATGTGGGGTGCT	52.4% identity		Open · Scan
MA0528.1	NN 70-40%	JASPAR	GGAGGAGGAGGGGGAGGAGGA	52.4% identity		Open · Scan
M05844_2.00	NN 70-40%	CisBP	TCACCTGT	52.2% identity		Open · Scan
MA0103.1	NN 70-40%	JASPAR	CACCTG	52.2% identity		Open · Scan
M07618_2.00	NN 70-40%	CisBP	CCTTTGGTGCTC	51.8% identity		Open · Scan
MA1154.1	NN 70-40%	JASPAR	CTTTCCCACAACACGAC	51.7% identity		Open · Scan
M07754_2.00	NN 70-40%	CisBP	CGCCCCCTCCCT	51.6% identity		Open · Scan
M07723_2.00	NN 70-40%	CisBP	CCGCTGCTCCCTGCT	51.5% identity		Open · Scan
M07777_2.00	NN 70-40%	CisBP	GCCAATTTCCGTGGTGTAAAT	51.5% identity		Open · Scan
M08373_2.00	NN 70-40%	CisBP	CCCCCTGGCTCTTCCTCT	51.5% identity		Open · Scan
M00142_2.00	NN 70-40%	CisBP	GTGCTCCT	51.4% identity		Open · Scan
M00764_2.00	NN 70-40%	CisBP	GTCTACAC	51.4% identity		Open · Scan
MA1596.1	NN 70-40%	JASPAR	GCCTCAGCCTCCCGAG	51.4% identity		Open · Scan
MA1656.1	NN 70-40%	JASPAR	CCAAGCCCAACCAG	51.2% identity		Open · Scan
M07628_2.00	NN 70-40%	CisBP	AGTGGTTCTGCTTCT	51.1% identity		Open · Scan
M01044_2.00	NN 70-40%	CisBP	TCTCTCTTTC	50.9% identity		Open · Scan
M07747_2.00	NN 70-40%	CisBP	TGGTCTATAAAGGGCCTGGTT	50.6% identity		Open · Scan
M08901_2.00	NN 70-40%	CisBP	CCAGTTCACACC	50.6% identity		Open · Scan
M07638_2.00	NN 70-40%	CisBP	TGCAGCTCCCTGCCC	50.4% identity		Open · Scan
M07764_2.00	NN 70-40%	CisBP	CTGCACTCTCCCCTTCCCCCCCTCCCC	50.3% identity		Open · Scan
M04430_2.00	NN 70-40%	CisBP	GACCACGCCCA	50.0% identity		Open · Scan
M07667_2.00	NN 70-40%	CisBP	CCGCACAGGCCCCCGGGCCCC	50.0% identity		Open · Scan
M08392_2.00	NN 70-40%	CisBP	CTTCACCTGCTGAGG	50.0% identity		Open · Scan
M08528_2.00	NN 70-40%	CisBP	ACCCCACTTTTTTG	50.0% identity		Open · Scan
MA0493.1	NN 70-40%	JASPAR	GGCCACACCCA	50.0% identity		Open · Scan
MA0742.1	NN 70-40%	JASPAR	GACCACGCCCTTATT	50.0% identity		Open · Scan
MA1515.1	NN 70-40%	JASPAR	CACCACGCCCA	50.0% identity		Open · Scan

ModCRE1

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
TFS_sp_Q08AN1_ZN616_HUMAN:490:600_5ei9_E_1	ModCRE	Homology model	GCCAAGAGGGGGGCCGC	Region 490-600 · 1 3D model		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 781 aa

267-318

437-763

Region 267-318 0 PWM

Residues

52 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

1 active PDB · 1 summary row

Templates

1LLM

Sources

Predicted = Low

Scan this region Show models

Region 437-763 1 PWM

Residues

327 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

6 active PDBs · 5 summary rows

Templates

2I13, 5EI9, 5V3J, 5V3M, 5WJQ, 7W1M

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

7 active PDB models 6 summary rows

Region 267-3181 model · 1 summary row

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_sp_Q08AN1_ZN616_HUMAN:267:318_1llm_C_1	1llm	267-318	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
1	1llm	433:763	267,267	318,318	P:C,D · DNA:A,B	42.3% / 67.3%	59,61	View · PDB DIMER_sp_Q08AN1_ZN616_HUMAN:267:318_1llm_C_1

Region 437-7636 models · 5 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	TFS_sp_Q08AN1_ZN616_HUMAN:437:712_5v3j_E_1	5v3j	437-712	View model · PDB
Predicted = Low	TFS_sp_Q08AN1_ZN616_HUMAN:437:712_5v3m_C_1	5v3m	437-712	View model · PDB
Predicted = Low	TFS_sp_Q08AN1_ZN616_HUMAN:462:740_5wjq_D_1	5wjq	462-740	View model · PDB
Predicted = Low	TFS_sp_Q08AN1_ZN616_HUMAN:465:763_7w1m_H_1	7w1m	465-763	View model · PDB
Predicted = Low	TFS_sp_Q08AN1_ZN616_HUMAN:490:600_5ei9_E_1	5ei9	490-600	View model · PDB
Predicted = Low	TFS_sp_Q08AN1_ZN616_HUMAN:502:655_2i13_A_1	2i13	502-655	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
4	2i13	433:763	502	655	P:A · DNA:C,D	61.7% / 72.7%	100	View · PDB TFS_sp_Q08AN1_ZN616_HUMAN:502:655_2i13_A_1
1	5wjq	433:763	462	740	P:D · DNA:A,B	57.0% / 71.0%	99	View · PDB TFS_sp_Q08AN1_ZN616_HUMAN:462:740_5wjq_D_1
2	5v3m	433:763	437	712	P:C · DNA:A,B	54.7% / 69.9%	99	View · PDB TFS_sp_Q08AN1_ZN616_HUMAN:437:712_5v3m_C_1
3	5v3j	433:763	437	712	P:E · DNA:A,B	54.7% / 69.9%	99	View · PDB TFS_sp_Q08AN1_ZN616_HUMAN:437:712_5v3j_E_1
5	7w1m	433:763	465	763	P:H · DNA:F,G	34.1% / 49.7%	92	View · PDB TFS_sp_Q08AN1_ZN616_HUMAN:465:763_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
7-47	PF01352	KRAB box	No overlap with loaded model regions
185-207	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
213-235	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
241-263	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
269-291	PF00096	Zinc finger, C2H2 type	overlaps 267-318
297-319	PF00096	Zinc finger, C2H2 type	overlaps 267-318
325-347	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
353-375	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
381-403	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
409-431	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
437-459	PF00096	Zinc finger, C2H2 type	overlaps 437-763
465-487	PF00096	Zinc finger, C2H2 type	overlaps 437-763
493-515	PF00096	Zinc finger, C2H2 type	overlaps 437-763
521-543	PF00096	Zinc finger, C2H2 type	overlaps 437-763
549-571	PF00096	Zinc finger, C2H2 type	overlaps 437-763
577-599	PF00096	Zinc finger, C2H2 type	overlaps 437-763
605-627	PF00096	Zinc finger, C2H2 type	overlaps 437-763
633-655	PF00096	Zinc finger, C2H2 type	overlaps 437-763
661-683	PF00096	Zinc finger, C2H2 type	overlaps 437-763
689-711	PF00096	Zinc finger, C2H2 type	overlaps 437-763
717-739	PF00096	Zinc finger, C2H2 type	overlaps 437-763
745-767	PF00096	Zinc finger, C2H2 type	overlaps 437-763