ModCRE DB

Transcription factor

Q12772 - SREBF2

Sterol regulatory element-binding protein 2 (SREBP-2) (Class D basic helix-loop-helix protein 2) (bHLHd2) (Sterol regulatory element-binding transcription factor 2) [Cleaved into: Processed sterol regulatory element-binding protein 2 (Transcription factor SREBF2)]

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 1141 aa

18 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known18
MotifPredictionSourceDNA bindingSupportLogoActions
MA0596.1 Known JASPAR ATGGGGTGAT Direct PWM Open · Scan
MA0828.1 Known JASPAR ATCACGTGAC Direct PWM Open · Scan
MA0828.2 Known JASPAR TTATCACGTGATAA Direct PWM Open · Scan
MA0828.3 Known JASPAR ATCACGTGAT Direct PWM Open · Scan
MA1933.1 Known JASPAR ACCGGAAGTGGCGTGA Direct PWM Open · Scan
MA1933.2 Known JASPAR CCGGAAGTGGCGTGA Direct PWM Open · Scan
MA1939.1 Known JASPAR GCCGGAAATCACGTGAT Direct PWM Open · Scan
MA1939.2 Known JASPAR CCGGAAATCACGTGAT Direct PWM Open · Scan
M02811_2.00 Known CisBP ATCACGTGAC Direct PWM Open · Scan
M03591_2.00 Known CisBP AATCACGCCACC Direct PWM Open · Scan
M04219_2.00 Known CisBP ATCACGCCAC Direct PWM Open · Scan
M04220_2.00 Known CisBP ATCACGTGAC Direct PWM Open · Scan
M04221_2.00 Known CisBP ATCACACCAT Direct PWM Open · Scan
M04222_2.00 Known CisBP ATCACCTGAT Direct PWM Open · Scan
M08059_2.00 Known CisBP ATCACCCCAT Direct PWM Open · Scan
M08741_2.00 Known CisBP CCTCACCCCACCC Direct PWM Open · Scan
M09462_2.00 Known CisBP CGGTCACGCCAC Direct PWM Open · Scan
SRBP2_HUMAN.H11MO.0.B Known HOCOMOCO GGGTGGGGTGAGG Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 1141 aa
323-398

Region 323-398 0 PWM

Residues
76 aa
Domains
PF00010 · Helix-loop-helix DNA-binding domain
3D models
1 active PDB
Templates
1HLO
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 323-3981 model
Actions
Predicted = Low DIMER_Q12772:323:398_1hlo_A_1 1hlo 323-398 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
331-381PF00010Helix-loop-helix DNA-binding domainoverlaps 323-398