Transcription factor

Q13485 - SMAD4

SMAD family member 4 (SMAD 4) (hSMAD4) (Deletion target in pancreatic carcinoma 4) (Mothers against decapentaplegic homolog 4) (MAD homolog 4) (Mothers against DPP homolog 4)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 552 aa

3 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known3

Motif	Prediction	Source	DNA binding	Support	Actions
M09377_2.00	Known	CisBP	AGGTGCCAGACAG	Direct PWM	Open · Scan
M09634_2.00	Known	CisBP	GGCCGTCTGG	Direct PWM	Open · Scan
SMAD4_HUMAN.H11MO.0.B	Known	HOCOMOCO	CTGTCTGGCACCT	Direct PWM	Open · Scan

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 552 aa

10-138

Region 10-138 0 PWM

Residues: 129 aa
Domains: PF03165 · MH1 domain
3D models: 1 active PDB
Templates: 3QSV
Sources: Structure model

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

1 active PDB model

Region 10-1381 model

				Actions
Predicted = Low	TFS_Q13485:10:138_3qsv_A_1	3qsv	10-138	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
37-137	PF03165	MH1 domain	overlaps 10-138
321-530	PF03166	MH2 domain	No overlap with loaded model regions