ModCRE DB

Transcription factor

Q13761 - RUNX3

Runt-related transcription factor 3 (Acute myeloid leukemia 2 protein) (Core-binding factor subunit alpha-3) (CBF-alpha-3) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEA2-alpha C) (PEBP2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 415 aa

12 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known12
MotifPredictionSourceDNA bindingSupportLogoActions
MA0684.1 Known JASPAR AAACCGCAAA Direct PWM Open · Scan
MA0684.2 Known JASPAR AAAACCTCAAAT Direct PWM Open · Scan
MA0684.3 Known JASPAR AACCTCAA Direct PWM Open · Scan
M02751_2.00 Known CisBP AACCACAA Direct PWM Open · Scan
M03464_2.00 Known CisBP TAACCGCAAACCGCAA Direct PWM Open · Scan
M03465_2.00 Known CisBP AAACCGCAAA Direct PWM Open · Scan
M03466_2.00 Known CisBP TAACCGCAAAAACCGCAA Direct PWM Open · Scan
M03467_2.00 Known CisBP AAACCGCAAA Direct PWM Open · Scan
M05731_2.00 Known CisBP CAAACCGCAAAAACCGCAAG Direct PWM Open · Scan
M05732_2.00 Known CisBP CAAACCACAAAAACCACGAAA Direct PWM Open · Scan
M09369_2.00 Known CisBP AAACCACAAA Direct PWM Open · Scan
RUNX3_HUMAN.H11MO.0.A Known HOCOMOCO TTTGTGGTTT Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 415 aa
54-181

Region 54-181 0 PWM

Residues
128 aa
Domains
PF00853 · Runt domain
3D models
1 active PDB
Templates
4L0Y
Sources
Structure model
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 54-1811 model
Actions
Predicted = Low TFS_Q13761:54:181_4l0y_A_1 4l0y 54-181 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
56-183PF00853Runt domainoverlaps 54-181
317-415PF08504Runx inhibition domainNo overlap with loaded model regions