ModCRE DB

Transcription factor

Q14526 - HIC1

Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 733 aa

4 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known4
MotifPredictionSourceDNA bindingSupportLogoActions
M04568_2.00 Known CisBP CGTGCCAACC Direct PWM Open · Scan
M04569_2.00 Known CisBP CATGCCAACC Direct PWM Open · Scan
M08924_2.00 Known CisBP GGGCAACCC Direct PWM Open · Scan
HIC1_HUMAN.H11MO.0.C Known HOCOMOCO GGGTTGCCC Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 733 aa
505-610

Region 505-610 0 PWM

Residues
106 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
1 active PDB
Templates
5T0U
Sources
Structure model
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 505-6101 model
Actions
Predicted = Low TFS_Q14526:505:610_5t0u_A_1 5t0u 505-610 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
37-151PF00651BTB/POZ domainNo overlap with loaded model regions
507-529PF00096Zinc finger, C2H2 typeoverlaps 505-610
535-557PF00096Zinc finger, C2H2 typeoverlaps 505-610
563-585PF00096Zinc finger, C2H2 typeoverlaps 505-610
591-613PF00096Zinc finger, C2H2 typeoverlaps 505-610