Transcription factor

Q14584 - ZNF266

Zinc finger protein 266 (Zinc finger protein HZF1)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 549 aa

81 Generated PWM 16 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known1

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M07641_2.00	Known	CisBP	ATTACTCACAGGCCC	Direct PWM		Open · Scan

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)70

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	59.5% identity		Open · Scan
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	58.8% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	58.8% identity		Open · Scan
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	58.8% identity		Open · Scan
MA1124.1	NN 70-40%	JASPAR	CATTCATTCATTC	58.4% identity		Open · Scan
M07689_2.00	NN 70-40%	CisBP	ACCCAGGCTCCTTCCATCTTGTGGCTC	58.3% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	57.6% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	57.6% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	57.6% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	57.6% identity		Open · Scan
M00955_2.00	NN 70-40%	CisBP	ACGTCCTCT	57.1% identity		Open · Scan
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	56.4% identity		Open · Scan
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	55.9% identity		Open · Scan
M08309_2.00	NN 70-40%	CisBP	AAAAACCCCCCTGCAGAGCCCAGCCCT	55.4% identity		Open · Scan
M04598_2.00	NN 70-40%	CisBP	CGCTAACTCTCCACA	55.2% identity		Open · Scan
M08325_2.00	NN 70-40%	CisBP	TTTTTTTTT	54.5% identity		Open · Scan
M07700_2.00	NN 70-40%	CisBP	ATGTTGTGAGGAAGCCCA	54.3% identity		Open · Scan
M08246_2.00	NN 70-40%	CisBP	GCCCCACCCA	54.3% identity		Open · Scan
MA1511.1	NN 70-40%	JASPAR	GCCACACCCCC	54.3% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	53.8% identity		Open · Scan
M08944_2.00	NN 70-40%	CisBP	TACCATGCTGTTTTGATTAC	53.8% identity		Open · Scan
M04650_2.00	NN 70-40%	CisBP	GCATAACTGCCCCGCTGCC	53.7% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	53.5% identity		Open · Scan
M08985_2.00	NN 70-40%	CisBP	TGAGGACCTACTGTGTGCC	53.5% identity		Open · Scan
M04611_2.00	NN 70-40%	CisBP	CTTTCGGACAC	53.4% identity		Open · Scan
M08295_2.00	NN 70-40%	CisBP	CTGCTGGAATCTCCA	53.3% identity		Open · Scan
M07733_2.00	NN 70-40%	CisBP	TCTTTCTCTCTCTCC	53.2% identity		Open · Scan
M08267_2.00	NN 70-40%	CisBP	CAGTTTCATTTTCC	53.2% identity		Open · Scan
M08934_2.00	NN 70-40%	CisBP	GCTGTACCTGCTTATTAGGC	53.0% identity		Open · Scan
M01474_2.00	NN 70-40%	CisBP	CGCCGATCAC	52.9% identity		Open · Scan
M04621_2.00	NN 70-40%	CisBP	AGCAATTCCGCTCA	52.5% identity		Open · Scan
MA1589.1	NN 70-40%	JASPAR	TAGGAGTGGAATTGCTGGGTC	52.5% identity		Open · Scan
MA1602.1	NN 70-40%	JASPAR	CGTCTACACGGG	52.5% identity		Open · Scan
M07683_2.00	NN 70-40%	CisBP	GTGGGAAAGCCT	52.4% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	52.4% identity		Open · Scan
MA1587.1	NN 70-40%	JASPAR	CCTCGACCTCCTGA	52.4% identity		Open · Scan
MA1601.1	NN 70-40%	JASPAR	ATGTGGGAAA	52.4% identity		Open · Scan
M00945_2.00	NN 70-40%	CisBP	CACCGCAC	52.3% identity		Open · Scan
M08254_2.00	NN 70-40%	CisBP	CTGCCCTGGGACTTT	52.3% identity		Open · Scan
M00609_2.00	NN 70-40%	CisBP	GGAAGCCCTA	52.2% identity		Open · Scan
M08917_2.00	NN 70-40%	CisBP	GCTGAGCCATGTGGGGTGCT	52.2% identity		Open · Scan
M08901_2.00	NN 70-40%	CisBP	CCAGTTCACACC	52.1% identity		Open · Scan
MA1656.1	NN 70-40%	JASPAR	CCAAGCCCAACCAG	52.1% identity		Open · Scan
M07578_2.00	NN 70-40%	CisBP	CAACTCTCC	51.6% identity		Open · Scan
M07620_2.00	NN 70-40%	CisBP	TTGGATCTGTGGATTCATGTCTTTCAT	51.5% identity		Open · Scan
M04387_2.00	NN 70-40%	CisBP	CGTGCTCCCC	51.3% identity		Open · Scan
M08373_2.00	NN 70-40%	CisBP	CCCCCTGGCTCTTCCTCT	51.3% identity		Open · Scan
M05859_2.00	NN 70-40%	CisBP	GGCCACGCCCACT	51.2% identity		Open · Scan
M08908_2.00	NN 70-40%	CisBP	GCTGCTGCTTCTGCTG	51.2% identity		Open · Scan
MA0685.1	NN 70-40%	JASPAR	TAAGCCACGCCCCCTTT	51.2% identity		Open · Scan
MA1588.1	NN 70-40%	JASPAR	GAATTCTTGGTTGAC	51.0% identity		Open · Scan
M06179_2.00	NN 70-40%	CisBP	TAAGCCTATAGA	50.9% identity		Open · Scan
M07658_2.00	NN 70-40%	CisBP	CCGCCGCAGCCGCCG	50.8% identity		Open · Scan
M08256_2.00	NN 70-40%	CisBP	GTGCCTT	50.7% identity		Open · Scan
MA0747.1	NN 70-40%	JASPAR	GCCACGCCCACT	50.6% identity		Open · Scan
M05853_2.00	NN 70-40%	CisBP	CCACCTTTAGCCATATCT	50.5% identity		Open · Scan
M07566_2.00	NN 70-40%	CisBP	TCAAACCATCCTTGC	50.5% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	50.2% identity		Open · Scan
M08347_2.00	NN 70-40%	CisBP	GCCCTGGGCAGC	50.1% identity		Open · Scan
M00224_2.00	NN 70-40%	CisBP	CCCGCCCC	50.0% identity		Open · Scan
M00765_2.00	NN 70-40%	CisBP	CCCGCCCCC	50.0% identity		Open · Scan
M02903_2.00	NN 70-40%	CisBP	ATGCCACGCCCCTTTTTG	50.0% identity		Open · Scan
M03682_2.00	NN 70-40%	CisBP	ACGCCACGCCCAGT	50.0% identity		Open · Scan
M04463_2.00	NN 70-40%	CisBP	CACCACGCCCA	50.0% identity		Open · Scan
M04536_2.00	NN 70-40%	CisBP	ACGTAACCCGATACC	50.0% identity		Open · Scan
M07707_2.00	NN 70-40%	CisBP	TCCCGC	50.0% identity		Open · Scan
MA0039.1	NN 70-40%	JASPAR	TAAAGGAAGG	50.0% identity		Open · Scan
MA0039.3	NN 70-40%	JASPAR	CCACACCCTGC	50.0% identity		Open · Scan
MA0079.1	NN 70-40%	JASPAR	GGGGCGGGGT	50.0% identity		Open · Scan
MA1564.1	NN 70-40%	JASPAR	GCCACGCCCCCC	50.0% identity		Open · Scan

ModCRE10

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
TFS_sp_Q14584_ZN266_HUMAN:116:206_5egb_A_1	ModCRE	Homology model	CGGCCGCCGGGACCCCCG	Region 116-206 · 1 3D model		Open · Scan
TFS_sp_Q14584_ZN266_HUMAN:116:206_5ei9_E_1	ModCRE	Homology model	GCGGGGGTGGGGCCCTC	Region 116-206 · 1 3D model		Open · Scan
TFS_sp_Q14584_ZN266_HUMAN:116:206_5v3j_E_1	ModCRE	Homology model	CCACAAAAAAT	Region 116-206 · 1 3D model		Open · Scan
TFS_sp_Q14584_ZN266_HUMAN:116:206_5v3m_C_1	ModCRE	Homology model	AACCGTTAGCGCC	Region 116-206 · 1 3D model		Open · Scan
TFS_sp_Q14584_ZN266_HUMAN:71:139_5egb_A_1	ModCRE	Homology model	CGGGGGCGTACCCAGC	Region 71-139 · 1 3D model		Open · Scan
TFS_sp_Q14584_ZN266_HUMAN:71:139_5eh2_F_1	ModCRE	Homology model	GGGGGGGGGGTGCGCG	Region 71-139 · 1 3D model		Open · Scan
TFS_sp_Q14584_ZN266_HUMAN:71:139_5ei9_E_1	ModCRE	Homology model	CCGGGGGGGGGTGCAC	Region 71-139 · 1 3D model		Open · Scan
TFS_sp_Q14584_ZN266_HUMAN:71:152_2i13_A_1	ModCRE	Homology model	GAAAACCAGAGGGTGGAGTT	Region 71-152 · 1 3D model		Open · Scan
TFS_sp_Q14584_ZN266_HUMAN:72:138_5wjq_D_1	ModCRE	Homology model	AAAAAGAAAGTCCCCC	Region 72-138 · 1 3D model		Open · Scan
TFS_sp_Q14584_ZN266_HUMAN:82:206_2i13_A_1	ModCRE	Homology model	GAGAAGTAACTGATAGAGAGA	Region 82-206 · 1 3D model		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 549 aa

71-206

237-542

Region 71-206 10 PWM

Residues

136 aa

Domains

No overlapping PFAM annotation recorded

3D models

10 active PDBs

Templates

2I13, 5EGB, 5EH2, 5EI9, 5V3J, 5V3M, 5WJQ

Sources

Predicted = Low

Scan this region Show models

Region 237-542 0 PWM

Residues

306 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

6 active PDBs · 6 summary rows

Templates

1LLM, 2I13, 5V3J, 5V3M, 5WJQ, 7W1M

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

16 active PDB models 6 summary rows

Region 71-20610 models

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	TFS_sp_Q14584_ZN266_HUMAN:116:206_5egb_A_1	5egb	116-206	View model · PDB
Predicted = Low	TFS_sp_Q14584_ZN266_HUMAN:116:206_5ei9_E_1	5ei9	116-206	View model · PDB
Predicted = Low	TFS_sp_Q14584_ZN266_HUMAN:116:206_5v3j_E_1	5v3j	116-206	View model · PDB
Predicted = Low	TFS_sp_Q14584_ZN266_HUMAN:116:206_5v3m_C_1	5v3m	116-206	View model · PDB
Predicted = Low	TFS_sp_Q14584_ZN266_HUMAN:71:139_5egb_A_1	5egb	71-139	View model · PDB
Predicted = Low	TFS_sp_Q14584_ZN266_HUMAN:71:139_5eh2_F_1	5eh2	71-139	View model · PDB
Predicted = Low	TFS_sp_Q14584_ZN266_HUMAN:71:139_5ei9_E_1	5ei9	71-139	View model · PDB
Predicted = Low	TFS_sp_Q14584_ZN266_HUMAN:71:152_2i13_A_1	2i13	71-152	View model · PDB
Predicted = Low	TFS_sp_Q14584_ZN266_HUMAN:72:138_5wjq_D_1	5wjq	72-138	View model · PDB
Predicted = Low	TFS_sp_Q14584_ZN266_HUMAN:82:206_2i13_A_1	2i13	82-206	View model · PDB

Region 237-5426 models · 6 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_sp_Q14584_ZN266_HUMAN:349:398_1llm_D_1	1llm	349-398	View model · PDB
Predicted = Low	TFS_sp_Q14584_ZN266_HUMAN:237:515_5wjq_D_1	5wjq	237-515	View model · PDB
Predicted = Low	TFS_sp_Q14584_ZN266_HUMAN:240:538_7w1m_H_1	7w1m	240-538	View model · PDB
Predicted = Low	TFS_sp_Q14584_ZN266_HUMAN:267:542_5v3j_E_1	5v3j	267-542	View model · PDB
Predicted = Low	TFS_sp_Q14584_ZN266_HUMAN:267:542_5v3m_C_1	5v3m	267-542	View model · PDB
Predicted = Low	TFS_sp_Q14584_ZN266_HUMAN:305:458_2i13_A_1	2i13	305-458	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
4	2i13	210:542	305	458	P:A · DNA:C,D	53.9% / 71.4%	100	View · PDB TFS_sp_Q14584_ZN266_HUMAN:305:458_2i13_A_1
1	5v3m	210:542	267	542	P:C · DNA:A,B	51.8% / 68.8%	99	View · PDB TFS_sp_Q14584_ZN266_HUMAN:267:542_5v3m_C_1
2	5v3j	210:542	267	542	P:E · DNA:A,B	51.8% / 68.8%	99	View · PDB TFS_sp_Q14584_ZN266_HUMAN:267:542_5v3j_E_1
3	5wjq	210:542	237	515	P:D · DNA:A,B	50.5% / 68.5%	99	View · PDB TFS_sp_Q14584_ZN266_HUMAN:237:515_5wjq_D_1
1	1llm	210:542	349,349	398,398	P:C,D · DNA:A,B	44.0% / 68.0%	57,58	View · PDB DIMER_sp_Q14584_ZN266_HUMAN:349:398_1llm_D_1
5	7w1m	210:542	240	538	P:H · DNA:F,G	34.7% / 50.0%	92	View · PDB TFS_sp_Q14584_ZN266_HUMAN:240:538_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
212-234	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
240-262	PF00096	Zinc finger, C2H2 type	overlaps 237-542
268-290	PF00096	Zinc finger, C2H2 type	overlaps 237-542
296-318	PF00096	Zinc finger, C2H2 type	overlaps 237-542
324-346	PF00096	Zinc finger, C2H2 type	overlaps 237-542
352-374	PF00096	Zinc finger, C2H2 type	overlaps 237-542
380-402	PF00096	Zinc finger, C2H2 type	overlaps 237-542
408-430	PF00096	Zinc finger, C2H2 type	overlaps 237-542
436-458	PF00096	Zinc finger, C2H2 type	overlaps 237-542
464-486	PF00096	Zinc finger, C2H2 type	overlaps 237-542
492-514	PF00096	Zinc finger, C2H2 type	overlaps 237-542
520-542	PF00096	Zinc finger, C2H2 type	overlaps 237-542