Transcription factor

Q14653 - IRF3

Interferon regulatory factor 3 (IRF-3)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 427 aa

9 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known9

Motif	Prediction	Source	DNA binding	Support	Actions
MA1418.1	Known	JASPAR	GGGAAACGGAAACCGAAACTG	Direct PWM	Open · Scan
MA1418.2	Known	JASPAR	GAAACGGAAACCGAAAC	Direct PWM	Open · Scan
M03331_2.00	Known	CisBP	GGGAAACGGAAACCGAAACTG	Direct PWM	Open · Scan
M05531_2.00	Known	CisBP	TCAGTTTCGCCGAAACCGAAACT	Direct PWM	Open · Scan
M05532_2.00	Known	CisBP	GCTGTTTCCTGGAAACCGAAAC	Direct PWM	Open · Scan
M05533_2.00	Known	CisBP	AGGAAACGGAAACCGAAACT	Direct PWM	Open · Scan
M05534_2.00	Known	CisBP	AGGAAAGGGAAACGGAAACA	Direct PWM	Open · Scan
M09234_2.00	Known	CisBP	GAAAGGGAAAGGGAAAGTGA	Direct PWM	Open · Scan
IRF3_HUMAN.H11MO.0.B	Known	HOCOMOCO	GAAAGGGAAAGGGAAAGTGA	Direct PWM	Open · Scan

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 427 aa

3-112

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

1 active PDB model

Region 3-1121 model

				Actions
Predicted = Low	DIMER_Q14653:3:112_1t2k_A_1	1t2k	3-112	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
8-110	PF00605	Interferon regulatory factor transcription factor	overlaps 3-112
202-379	PF10401	Interferon-regulatory factor 3	No overlap with loaded model regions