Transcription factor

Q14765 - STAT4

Signal transducer and activator of transcription 4

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 748 aa

3 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known3

Motif	Prediction	Source	DNA binding	Support	Actions
M11361_2.00	Known	CisBP	GATTTCCA	Direct PWM	Open · Scan
M09413_2.00	Known	CisBP	TTTCCTGGAAG	Direct PWM	Open · Scan
STAT4_HUMAN.H11MO.0.A	Known	HOCOMOCO	TTTCCTGGAAG	Direct PWM	Open · Scan

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 748 aa

230-678

Residues: 449 aa
Domains: PF01017 · STAT transcription factor, coiled-coil domain PF02864 · STAT protein, DNA binding domain PF21354 · Signal transducer and activator of transcription, linker domain PF00017 · SH2 domain
3D models: 1 active PDB
Templates: 4Y5W
Sources: Structure model

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

1 active PDB model

Region 230-6781 model

				Actions
Predicted = Low	DIMER_Q14765:230:678_4y5w_A_1	4y5w	230-678	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
2-119	PF02865	STAT protein, protein interaction domain	No overlap with loaded model regions
144-308	PF01017	STAT transcription factor, coiled-coil domain	overlaps 230-678
321-454	PF02864	STAT protein, DNA binding domain	overlaps 230-678
478-554	PF21354	Signal transducer and activator of transcription, linker domain	overlaps 230-678
573-627	PF00017	SH2 domain	overlaps 230-678