Region 49-117 3 PWM
- Residues
- 69 aa
- Domains
- PF02319 · E2F/DP family winged-helix DNA-binding domain
- 3D models
- 3 active PDBs · 3 summary rows
- Templates
- 1CF7, 4YO2
- Sources
- Predicted = Low
Transcription factor
Q15329 - E2F5
Transcription factor E2F5 (E2F-5)
Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 346 aa
Motif Prediction
Only entries with a generated matrix are shown here.
Known2
| Motif | Prediction | Source | DNA binding | Support | Logo | Actions |
|---|---|---|---|---|---|---|
| M09032_2.00 | Known | CisBP | CGCGCCAAAC | Direct PWM | Open · Scan | |
| E2F5_HUMAN.H11MO.0.B | Known | HOCOMOCO | CGCGCCAAAC | Direct PWM | Open · Scan |
Nearest Neighbor (>70%)0
No generated PWM in this category.
Nearest Neighbor (70% - 40%)3
| Motif | Prediction | Source | DNA binding | Support | Logo | Actions |
|---|---|---|---|---|---|---|
| MA0470.1 | NN 70-40% | JASPAR | GGGCGGGAAGG | 52.1% identity | Open · Scan | |
| M01968_2.00 | NN 70-40% | CisBP | GCGCGCCAAA | 51.8% identity | Open · Scan | |
| M06871_2.00 | NN 70-40% | CisBP | ATTTGGCGCCAAAA | 51.5% identity | Open · Scan |
ModCRE3
| Motif | Prediction | Source | DNA binding | Support | Logo | Actions |
|---|---|---|---|---|---|---|
| TFS_sp_Q15329_E2F5_HUMAN:49:115_1cf7_A_1 | ModCRE | Homology model | AATTGCCGGGTTTAC | Region 49-115 · 1 3D model | Open · Scan | |
| TFS_sp_Q15329_E2F5_HUMAN:49:116_4yo2_A_1 | ModCRE | Homology model | TTTCCCCGCCCAAAA | Region 49-116 · 1 3D model | Open · Scan | |
| TFS_sp_Q15329_E2F5_HUMAN:88:117_1cf7_B_1 | ModCRE | Homology model | TTTTTTCGCGCGCCC | Region 88-117 · 1 3D model | Open · Scan |
Model-supported DNA-binding regions
Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.
1
346 aa
49-117
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
3 active PDB models
3 summary rows
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
Region 49-1173 models · 3 summary rows
| Actions | ||||
|---|---|---|---|---|
| Predicted = Low | TFS_sp_Q15329_E2F5_HUMAN:49:115_1cf7_A_1 | 1cf7 | 49-115 | View model · PDB |
| Predicted = Low | TFS_sp_Q15329_E2F5_HUMAN:49:116_4yo2_A_1 | 4yo2 | 49-116 | View model · PDB |
| Predicted = Low | TFS_sp_Q15329_E2F5_HUMAN:88:117_1cf7_B_1 | 1cf7 | 88-117 | View model · PDB |
Model-summary evidence imported for this region.
| Rank | Template | Domain | N-tails | C-tails | Chains | Identity / similarity | Coverage | Model file |
|---|---|---|---|---|---|---|---|---|
| 1 | 1cf7 | 49:117 | 49 | 115 | P:A · DNA:C,D | 97.0% / 97.0% | 100 | View · PDB TFS_sp_Q15329_E2F5_HUMAN:49:115_1cf7_A_1 |
| 3 | 1cf7 | 49:117 | 88 | 117 | P:B · DNA:C,D | 43.3% / 70.0% | 35 | View · PDB TFS_sp_Q15329_E2F5_HUMAN:88:117_1cf7_B_1 |
| 2 | 4yo2 | 49:117 | 49 | 116 | P:A · DNA:C,D | 38.0% / 56.3% | 36 | View · PDB TFS_sp_Q15329_E2F5_HUMAN:49:116_4yo2_A_1 |
View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.
Domains
Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.
| Residues | PFAM | Domain | Used by prediction region? |
|---|---|---|---|
| 52-116 | PF02319 | E2F/DP family winged-helix DNA-binding domain | overlaps 49-117 |
| 133-230 | PF16421 | E2F transcription factor CC-MB domain | No overlap with loaded model regions |