Transcription factor

Q15475 - SIX1

Homeobox protein SIX1 (Sine oculis homeobox homolog 1)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 284 aa

9 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known9

Motif	Prediction	Source	DNA binding	Support	Actions
MA1118.1	Known	JASPAR	GTAACCTGATA	Direct PWM	Open · Scan
MA1118.2	Known	JASPAR	GTAACCTGA	Direct PWM	Open · Scan
M05094_2.00	Known	CisBP	AATGATACGG	Direct PWM	Open · Scan
M05095_2.00	Known	CisBP	CATGATACGT	Direct PWM	Open · Scan
M05096_2.00	Known	CisBP	CATGATACGC	Direct PWM	Open · Scan
M05097_2.00	Known	CisBP	CATGATACGC	Direct PWM	Open · Scan
M08130_2.00	Known	CisBP	GTAACCTGATA	Direct PWM	Open · Scan
M09142_2.00	Known	CisBP	TGAAACCTGATACC	Direct PWM	Open · Scan
SIX1_HUMAN.H11MO.0.A	Known	HOCOMOCO	TGAAACCTGATACC	Direct PWM	Open · Scan

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE0

No generated PWM in this category.

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 284 aa

131-178

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

1 active PDB model

Region 131-1781 model

				Actions
Predicted = Low	DIMER_Q15475:131:178_1b8i_B_1	1b8i	131-178	View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
9-119	PF16878	Transcriptional regulator, SIX1, N-terminal SD domain	No overlap with loaded model regions
145-178	PF05920	Homeobox KN domain	overlaps 131-178