ModCRE DB

Transcription factor

Q15697 - ZNF174

Zinc finger protein 174 (AW-1) (Zinc finger and SCAN domain-containing protein 8)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 407 aa

100 Generated PWM 11 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known2
MotifPredictionSourceDNA bindingSupportLogoActions
M04414_2.00 Known CisBP GGCCGATCACTTGCCA Direct PWM Open · Scan
M04415_2.00 Known CisBP TGCCGATCACTCGCCC Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)93
MotifPredictionSourceDNA bindingSupportLogoActions
M07714_2.00 NN 70-40% CisBP AGCCCATTGGGGCCTATGCCC 60.7% identity Open · Scan
M08917_2.00 NN 70-40% CisBP GCTGAGCCATGTGGGGTGCT 59.7% identity Open · Scan
M07562_2.00 NN 70-40% CisBP GAAAAAAAC 58.6% identity Open · Scan
M08314_2.00 NN 70-40% CisBP ATTCATCAAGGTCCTCAACAATGG 58.6% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 58.4% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 58.4% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 57.9% identity Open · Scan
M08247_2.00 NN 70-40% CisBP AAAAATAACAAACGG 57.6% identity Open · Scan
MA1594.1 NN 70-40% JASPAR AGGGGACATCACTACAGATCCCAC 57.6% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 57.3% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 56.8% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 56.8% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 56.8% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 56.8% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 56.8% identity Open · Scan
M07689_2.00 NN 70-40% CisBP ACCCAGGCTCCTTCCATCTTGTGGCTC 56.5% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 56.4% identity Open · Scan
M07679_2.00 NN 70-40% CisBP TGCGATCTC 56.1% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 55.6% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 55.6% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 55.6% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 55.6% identity Open · Scan
M07605_2.00 NN 70-40% CisBP TATTTTTTTTTATTTTTTTTTTTTTTTTTT 55.6% identity Open · Scan
M00149_2.00 NN 70-40% CisBP CGTACGCC 55.4% identity Open · Scan
M00764_2.00 NN 70-40% CisBP GTCTACAC 55.4% identity Open · Scan
M08252_2.00 NN 70-40% CisBP CCGGCTCCAGCACCC 55.4% identity Open · Scan
M08914_2.00 NN 70-40% CisBP ATTTAGTCCATTTACATTTAATGT 55.4% identity Open · Scan
MA1587.1 NN 70-40% JASPAR CCTCGACCTCCTGA 55.4% identity Open · Scan
M00250_2.00 NN 70-40% CisBP AATGCTAACT 55.2% identity Open · Scan
M07761_2.00 NN 70-40% CisBP CTGATTATTCACCCA 55.2% identity Open · Scan
M04621_2.00 NN 70-40% CisBP AGCAATTCCGCTCA 55.0% identity Open · Scan
MA1589.1 NN 70-40% JASPAR TAGGAGTGGAATTGCTGGGTC 55.0% identity Open · Scan
M04475_2.00 NN 70-40% CisBP GATGCACGTACCGTGCCTCA 54.9% identity Open · Scan
MA1602.1 NN 70-40% JASPAR CGTCTACACGGG 54.8% identity Open · Scan
M08279_2.00 NN 70-40% CisBP CCTCCCTCC 54.7% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 54.5% identity Open · Scan
M07598_2.00 NN 70-40% CisBP CTGACAATACCAAGTGTTGAC 54.4% identity Open · Scan
M07581_2.00 NN 70-40% CisBP TCCCCTGTGCTTCTCTCCCCT 54.3% identity Open · Scan
M07678_2.00 NN 70-40% CisBP CCCGCCCCCTCCTCCCCCTTCCCACCC 54.3% identity Open · Scan
M07712_2.00 NN 70-40% CisBP ACATTTTTTTAATCTAAAAAAACATTTACA 54.3% identity Open · Scan
M08291_2.00 NN 70-40% CisBP AATCCAGCCCTAGACTCTCCC 54.3% identity Open · Scan
M08309_2.00 NN 70-40% CisBP AAAAACCCCCCTGCAGAGCCCAGCCCT 54.3% identity Open · Scan
M08375_2.00 NN 70-40% CisBP TTCCCCATTGGCTACTGCACCGGTCCT 54.3% identity Open · Scan
M07770_2.00 NN 70-40% CisBP CTTGGACTT 54.2% identity Open · Scan
M08373_2.00 NN 70-40% CisBP CCCCCTGGCTCTTCCTCT 54.2% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 53.9% identity Open · Scan
M08334_2.00 NN 70-40% CisBP TTTGTTTTTTTCTGATTGCTTTTTACTTAT 53.9% identity Open · Scan
M08392_2.00 NN 70-40% CisBP CTTCACCTGCTGAGG 53.8% identity Open · Scan
M07567_2.00 NN 70-40% CisBP CCACTCCACTCA 53.2% identity Open · Scan
M07667_2.00 NN 70-40% CisBP CCGCACAGGCCCCCGGGCCCC 53.2% identity Open · Scan
M08347_2.00 NN 70-40% CisBP GCCCTGGGCAGC 53.2% identity Open · Scan
M08371_2.00 NN 70-40% CisBP CCAGACTTGTCCTCT 53.2% identity Open · Scan
M00217_2.00 NN 70-40% CisBP TTACTCAATAT 53.1% identity Open · Scan
M07579_2.00 NN 70-40% CisBP CATCTCCAGGA 53.1% identity Open · Scan
M07610_2.00 NN 70-40% CisBP CCTTCTTCCTCCCCCCTGCCCACC 53.1% identity Open · Scan
M08267_2.00 NN 70-40% CisBP CAGTTTCATTTTCC 53.0% identity Open · Scan
M08283_2.00 NN 70-40% CisBP GACTTTTATTTT 52.7% identity Open · Scan
M08357_2.00 NN 70-40% CisBP GAGCCTGCTACTGAGCCTGGG 52.7% identity Open · Scan
M07680_2.00 NN 70-40% CisBP AACCCCAAC 52.6% identity Open · Scan
M08255_2.00 NN 70-40% CisBP CTCTTCCGGT 52.6% identity Open · Scan
M05853_2.00 NN 70-40% CisBP CCACCTTTAGCCATATCT 52.1% identity Open · Scan
M07635_2.00 NN 70-40% CisBP AAGTTTTCTTGTATTATATCT 52.1% identity Open · Scan
M07645_2.00 NN 70-40% CisBP CTCCTT 52.1% identity Open · Scan
M07660_2.00 NN 70-40% CisBP CCGCGCCTACCTGAGGGCGCGGGCCTGGGG 52.1% identity Open · Scan
M07699_2.00 NN 70-40% CisBP GGTTTAT 52.1% identity Open · Scan
M08256_2.00 NN 70-40% CisBP GTGCCTT 52.1% identity Open · Scan
M08395_2.00 NN 70-40% CisBP GCTGCCTACTCTTCC 52.1% identity Open · Scan
M08934_2.00 NN 70-40% CisBP GCTGTACCTGCTTATTAGGC 52.0% identity Open · Scan
M08311_2.00 NN 70-40% CisBP CTGGAACAGAAGGGGCGA 51.9% identity Open · Scan
M07587_2.00 NN 70-40% CisBP CCCCCTCCCCAGTCGAGCCCCCGC 51.6% identity Open · Scan
MA1154.1 NN 70-40% JASPAR CTTTCCCACAACACGAC 51.6% identity Open · Scan
M08944_2.00 NN 70-40% CisBP TACCATGCTGTTTTGATTAC 51.4% identity Open · Scan
M07649_2.00 NN 70-40% CisBP CCCCCCCCCCCCTCAGGAATGCC 51.0% identity Open · Scan
M08860_2.00 NN 70-40% CisBP TCTTATAAGGGCACTAATCCCATT 50.9% identity Open · Scan
M03711_2.00 NN 70-40% CisBP TTTTTTTTGCATTTTTT 50.6% identity Open · Scan
M04587_2.00 NN 70-40% CisBP GTACCTACCGC 50.6% identity Open · Scan
M05844_2.00 NN 70-40% CisBP TCACCTGT 50.6% identity Open · Scan
M07720_2.00 NN 70-40% CisBP TGTGTGTGTGGGCATGTGTGTGTGCGAGT 50.6% identity Open · Scan
MA0103.1 NN 70-40% JASPAR CACCTG 50.6% identity Open · Scan
MA0103.2 NN 70-40% JASPAR CCTCACCTG 50.6% identity Open · Scan
MA1650.1 NN 70-40% JASPAR CCCCGCGCACCC 50.6% identity Open · Scan
M00142_2.00 NN 70-40% CisBP GTGCTCCT 50.5% identity Open · Scan
M02896_2.00 NN 70-40% CisBP TGCTTTCTAGGAATTCA 50.5% identity Open · Scan
M07717_2.00 NN 70-40% CisBP GGCTCCGCCCCC 50.5% identity Open · Scan
M08366_2.00 NN 70-40% CisBP GTTTGCTGCTTACAA 50.5% identity Open · Scan
MA0695.1 NN 70-40% JASPAR GCGACCACCGAA 50.5% identity Open · Scan
MA0731.1 NN 70-40% JASPAR TGCTTTCTAGGAATTCA 50.5% identity Open · Scan
M04590_2.00 NN 70-40% CisBP TGCGCTAACCATTGC 50.0% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 50.0% identity Open · Scan
M07623_2.00 NN 70-40% CisBP GTCTAATAGAGCTGGGCTGCA 50.0% identity Open · Scan
M07703_2.00 NN 70-40% CisBP CCGACGG 50.0% identity Open · Scan
M08254_2.00 NN 70-40% CisBP CTGCCCTGGGACTTT 50.0% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 50.0% identity Open · Scan
ModCRE5
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_sp_Q15697_ZN174_HUMAN:322:404_4r2q_A_1 ModCRE Homology model GGGGGGGCCC Region 322-404 · 1 3D model Open · Scan
TFS_sp_Q15697_ZN174_HUMAN:322:404_4r2r_A_1 ModCRE Homology model GGGGGGGCGG Region 322-404 · 1 3D model Open · Scan
TFS_sp_Q15697_ZN174_HUMAN:322:404_5kl5_A_1 ModCRE Homology model GGGGGGGGCC Region 322-404 · 1 3D model Open · Scan
TFS_sp_Q15697_ZN174_HUMAN:323:404_5kl2_A_1 ModCRE Homology model GAGGGGGGGG Region 323-404 · 1 3D model Open · Scan
TFS_sp_Q15697_ZN174_HUMAN:326:404_2kmk_A_1 ModCRE Homology model AAAAGAGCGGGGGGAG Region 326-404 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 407 aa
281-407

Region 281-407 5 PWM

Residues
127 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
11 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 2KMK, 4R2Q, 4R2R, 5EI9, 5KL2, 5KL5, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
11 active PDB models 6 summary rows
Region 281-40711 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_Q15697_ZN174_HUMAN:352:405_1llm_D_1 1llm 352-405 View model · PDB
Predicted = Low TFS_sp_Q15697_ZN174_HUMAN:281:407_2i13_A_1 2i13 281-407 View model · PDB
Predicted = Low TFS_sp_Q15697_ZN174_HUMAN:305:404_5ei9_E_1 5ei9 305-404 View model · PDB
Predicted = Low TFS_sp_Q15697_ZN174_HUMAN:316:404_5v3j_E_1 5v3j 316-404 View model · PDB
Predicted = Low TFS_sp_Q15697_ZN174_HUMAN:316:404_5v3m_C_1 5v3m 316-404 View model · PDB
Predicted = Low TFS_sp_Q15697_ZN174_HUMAN:316:407_5wjq_D_1 5wjq 316-407 View model · PDB
Predicted = Low TFS_sp_Q15697_ZN174_HUMAN:322:404_4r2q_A_1 4r2q 322-404 View model · PDB
Predicted = Low TFS_sp_Q15697_ZN174_HUMAN:322:404_4r2r_A_1 4r2r 322-404 View model · PDB
Predicted = Low TFS_sp_Q15697_ZN174_HUMAN:322:404_5kl5_A_1 5kl5 322-404 View model · PDB
Predicted = Low TFS_sp_Q15697_ZN174_HUMAN:323:404_5kl2_A_1 5kl2 323-404 View model · PDB
Predicted = Low TFS_sp_Q15697_ZN174_HUMAN:326:404_2kmk_A_1 2kmk 326-404 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
3 5v3m 281:407 316 404 P:C · DNA:A,B 55.1% / 73.0% 32 View · PDB TFS_sp_Q15697_ZN174_HUMAN:316:404_5v3m_C_1
4 5v3j 281:407 316 404 P:E · DNA:A,B 55.1% / 73.0% 32 View · PDB TFS_sp_Q15697_ZN174_HUMAN:316:404_5v3j_E_1
2 5wjq 281:407 316 407 P:D · DNA:A,B 53.3% / 71.7% 32 View · PDB TFS_sp_Q15697_ZN174_HUMAN:316:407_5wjq_D_1
5 5ei9 281:407 305 404 P:E · DNA:A,B 51.0% / 63.0% 90 View · PDB TFS_sp_Q15697_ZN174_HUMAN:305:404_5ei9_E_1
1 2i13 281:407 281 407 P:A · DNA:C,D 44.1% / 63.8% 82 View · PDB TFS_sp_Q15697_ZN174_HUMAN:281:407_2i13_A_1
1 1llm 281:407 352,352 405,405 P:C,D · DNA:A,B 38.9% / 51.9% 62,63 View · PDB DIMER_sp_Q15697_ZN174_HUMAN:352:405_1llm_D_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
42-130PF02023SCAN domainNo overlap with loaded model regions
326-348PF00096Zinc finger, C2H2 typeoverlaps 281-407
354-376PF00096Zinc finger, C2H2 typeoverlaps 281-407
382-404PF00096Zinc finger, C2H2 typeoverlaps 281-407