ModCRE DB

Transcription factor

Q15776 - ZKSCAN8

Zinc finger protein with KRAB and SCAN domains 8 (LD5-1) (Zinc finger protein 192)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 578 aa

132 Generated PWM 11 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)121
MotifPredictionSourceDNA bindingSupportLogoActions
M00939_2.00 NN 70-40% CisBP CCACCTCA 68.2% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 67.3% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 67.0% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 67.0% identity Open · Scan
MA1587.1 NN 70-40% JASPAR CCTCGACCTCCTGA 66.7% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 65.8% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 65.8% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 65.8% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 65.8% identity Open · Scan
M07635_2.00 NN 70-40% CisBP AAGTTTTCTTGTATTATATCT 65.2% identity Open · Scan
M07689_2.00 NN 70-40% CisBP ACCCAGGCTCCTTCCATCTTGTGGCTC 64.9% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 64.7% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 64.7% identity Open · Scan
M07700_2.00 NN 70-40% CisBP ATGTTGTGAGGAAGCCCA 64.6% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 63.5% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 63.5% identity Open · Scan
M08334_2.00 NN 70-40% CisBP TTTGTTTTTTTCTGATTGCTTTTTACTTAT 62.8% identity Open · Scan
M08375_2.00 NN 70-40% CisBP TTCCCCATTGGCTACTGCACCGGTCCT 62.8% identity Open · Scan
M08944_2.00 NN 70-40% CisBP TACCATGCTGTTTTGATTAC 62.8% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 62.5% identity Open · Scan
M04653_2.00 NN 70-40% CisBP GGTACGGTTGTCCATGTTGCAA 62.5% identity Open · Scan
M08371_2.00 NN 70-40% CisBP CCAGACTTGTCCTCT 62.1% identity Open · Scan
M07764_2.00 NN 70-40% CisBP CTGCACTCTCCCCTTCCCCCCCTCCCC 61.7% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 61.5% identity Open · Scan
M08252_2.00 NN 70-40% CisBP CCGGCTCCAGCACCC 61.4% identity Open · Scan
M08256_2.00 NN 70-40% CisBP GTGCCTT 61.4% identity Open · Scan
M08395_2.00 NN 70-40% CisBP GCTGCCTACTCTTCC 61.4% identity Open · Scan
M08254_2.00 NN 70-40% CisBP CTGCCCTGGGACTTT 61.1% identity Open · Scan
M07649_2.00 NN 70-40% CisBP CCCCCCCCCCCCTCAGGAATGCC 60.9% identity Open · Scan
M08347_2.00 NN 70-40% CisBP GCCCTGGGCAGC 60.9% identity Open · Scan
M07581_2.00 NN 70-40% CisBP TCCCCTGTGCTTCTCTCCCCT 60.5% identity Open · Scan
M05853_2.00 NN 70-40% CisBP CCACCTTTAGCCATATCT 60.2% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 60.0% identity Open · Scan
M08267_2.00 NN 70-40% CisBP CAGTTTCATTTTCC 60.0% identity Open · Scan
M08934_2.00 NN 70-40% CisBP GCTGTACCTGCTTATTAGGC 60.0% identity Open · Scan
M07598_2.00 NN 70-40% CisBP CTGACAATACCAAGTGTTGAC 59.9% identity Open · Scan
M08279_2.00 NN 70-40% CisBP CCTCCCTCC 59.8% identity Open · Scan
M04621_2.00 NN 70-40% CisBP AGCAATTCCGCTCA 59.7% identity Open · Scan
M07587_2.00 NN 70-40% CisBP CCCCCTCCCCAGTCGAGCCCCCGC 59.7% identity Open · Scan
M07753_2.00 NN 70-40% CisBP TGCATTCCTTGGCTTGTG 59.7% identity Open · Scan
MA1589.1 NN 70-40% JASPAR TAGGAGTGGAATTGCTGGGTC 59.7% identity Open · Scan
M08255_2.00 NN 70-40% CisBP CTCTTCCGGT 59.5% identity Open · Scan
M08914_2.00 NN 70-40% CisBP ATTTAGTCCATTTACATTTAATGT 59.5% identity Open · Scan
M07588_2.00 NN 70-40% CisBP TCCTTCCCTCTTTCC 59.3% identity Open · Scan
M07579_2.00 NN 70-40% CisBP CATCTCCAGGA 59.2% identity Open · Scan
M07660_2.00 NN 70-40% CisBP CCGCGCCTACCTGAGGGCGCGGGCCTGGGG 59.1% identity Open · Scan
M04610_2.00 NN 70-40% CisBP CGGCGACGCGAACAC 59.0% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 58.6% identity Open · Scan
M07712_2.00 NN 70-40% CisBP ACATTTTTTTAATCTAAAAAAACATTTACA 58.5% identity Open · Scan
M08292_2.00 NN 70-40% CisBP TGTATTCCTTGTCATGTGTGG 58.5% identity Open · Scan
M07727_2.00 NN 70-40% CisBP CGCCGCCTCCCC 58.4% identity Open · Scan
MA1596.1 NN 70-40% JASPAR GCCTCAGCCTCCCGAG 58.4% identity Open · Scan
M07707_2.00 NN 70-40% CisBP TCCCGC 58.3% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 58.3% identity Open · Scan
M07605_2.00 NN 70-40% CisBP TATTTTTTTTTATTTTTTTTTTTTTTTTTT 58.2% identity Open · Scan
M07777_2.00 NN 70-40% CisBP GCCAATTTCCGTGGTGTAAAT 58.2% identity Open · Scan
M07610_2.00 NN 70-40% CisBP CCTTCTTCCTCCCCCCTGCCCACC 57.8% identity Open · Scan
M07699_2.00 NN 70-40% CisBP GGTTTAT 57.8% identity Open · Scan
M08373_2.00 NN 70-40% CisBP CCCCCTGGCTCTTCCTCT 57.8% identity Open · Scan
M07678_2.00 NN 70-40% CisBP CCCGCCCCCTCCTCCCCCTTCCCACCC 57.5% identity Open · Scan
M07691_2.00 NN 70-40% CisBP CCTGCAGCCACCTTGGCCTTG 57.4% identity Open · Scan
M07723_2.00 NN 70-40% CisBP CCGCTGCTCCCTGCT 57.0% identity Open · Scan
M08386_2.00 NN 70-40% CisBP GCCTTAAAAGCTCAGCAC 56.8% identity Open · Scan
M01456_2.00 NN 70-40% CisBP GTGATCGGCG 56.6% identity Open · Scan
M08335_2.00 NN 70-40% CisBP AGTCGTTGTCTG 56.6% identity Open · Scan
M08860_2.00 NN 70-40% CisBP TCTTATAAGGGCACTAATCCCATT 56.6% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 56.5% identity Open · Scan
MA1154.1 NN 70-40% JASPAR CTTTCCCACAACACGAC 56.1% identity Open · Scan
M04536_2.00 NN 70-40% CisBP ACGTAACCCGATACC 56.0% identity Open · Scan
M07761_2.00 NN 70-40% CisBP CTGATTATTCACCCA 56.0% identity Open · Scan
M04505_2.00 NN 70-40% CisBP AGCTTTTCCCACAC 55.8% identity Open · Scan
M08300_2.00 NN 70-40% CisBP CTGCCCAATTCAT 55.8% identity Open · Scan
M08392_2.00 NN 70-40% CisBP CTTCACCTGCTGAGG 55.8% identity Open · Scan
M07648_2.00 NN 70-40% CisBP GCTTGCAAAAAAAATTTAACTCCCAGCTC 55.7% identity Open · Scan
M08291_2.00 NN 70-40% CisBP AATCCAGCCCTAGACTCTCCC 55.6% identity Open · Scan
M00134_2.00 NN 70-40% CisBP GCCACGCCCA 55.5% identity Open · Scan
M07607_2.00 NN 70-40% CisBP GGCTCCACG 55.4% identity Open · Scan
M08342_2.00 NN 70-40% CisBP GCTCTGCCTCCCTCT 55.4% identity Open · Scan
M07567_2.00 NN 70-40% CisBP CCACTCCACTCA 55.0% identity Open · Scan
M07601_2.00 NN 70-40% CisBP CAGATGCCGGCACCATGCTTC 55.0% identity Open · Scan
M07686_2.00 NN 70-40% CisBP TAGCTTGTTTCCAGCCAC 55.0% identity Open · Scan
M00786_2.00 NN 70-40% CisBP TATATATAT 54.9% identity Open · Scan
M08247_2.00 NN 70-40% CisBP AAAAATAACAAACGG 54.9% identity Open · Scan
MA1594.1 NN 70-40% JASPAR AGGGGACATCACTACAGATCCCAC 54.9% identity Open · Scan
M07729_2.00 NN 70-40% CisBP CCAGACTGCCTGCCAAAACCCCCT 54.1% identity Open · Scan
M07613_2.00 NN 70-40% CisBP TCACTCAGTCATTCA 54.0% identity Open · Scan
M08917_2.00 NN 70-40% CisBP GCTGAGCCATGTGGGGTGCT 54.0% identity Open · Scan
M08399_2.00 NN 70-40% CisBP TACTCTGGGGCCACATGACTC 53.9% identity Open · Scan
M05844_2.00 NN 70-40% CisBP TCACCTGT 53.6% identity Open · Scan
MA0103.1 NN 70-40% JASPAR CACCTG 53.6% identity Open · Scan
MA0103.2 NN 70-40% JASPAR CCTCACCTG 53.6% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 53.3% identity Open · Scan
M07646_2.00 NN 70-40% CisBP CTTTTTTTT 53.1% identity Open · Scan
M08283_2.00 NN 70-40% CisBP GACTTTTATTTT 53.1% identity Open · Scan
M07623_2.00 NN 70-40% CisBP GTCTAATAGAGCTGGGCTGCA 52.7% identity Open · Scan
M08889_2.00 NN 70-40% CisBP GCTGCTCTTTTT 52.6% identity Open · Scan
M07740_2.00 NN 70-40% CisBP TCCTGATTCCACACTCAAACATAACTTT 52.4% identity Open · Scan
MA1588.1 NN 70-40% JASPAR GAATTCTTGGTTGAC 52.3% identity Open · Scan
M08357_2.00 NN 70-40% CisBP GAGCCTGCTACTGAGCCTGGG 52.2% identity Open · Scan
M07645_2.00 NN 70-40% CisBP CTCCTT 51.9% identity Open · Scan
M00609_2.00 NN 70-40% CisBP GGAAGCCCTA 51.3% identity Open · Scan
M00779_2.00 NN 70-40% CisBP GCCACGCCCA 51.3% identity Open · Scan
M04463_2.00 NN 70-40% CisBP CACCACGCCCA 51.3% identity Open · Scan
M08867_2.00 NN 70-40% CisBP CACCCCCTG 51.3% identity Open · Scan
MA0039.1 NN 70-40% JASPAR TAAAGGAAGG 51.3% identity Open · Scan
MA0039.3 NN 70-40% JASPAR CCACACCCTGC 51.3% identity Open · Scan
MA0493.1 NN 70-40% JASPAR GGCCACACCCA 51.3% identity Open · Scan
MA1515.1 NN 70-40% JASPAR CACCACGCCCA 51.3% identity Open · Scan
M07562_2.00 NN 70-40% CisBP GAAAAAAAC 51.1% identity Open · Scan
MA1602.1 NN 70-40% JASPAR CGTCTACACGGG 50.8% identity Open · Scan
M07693_2.00 NN 70-40% CisBP CTCCTGTGTGTGCCTTGGCTG 50.3% identity Open · Scan
M00147_2.00 NN 70-40% CisBP TGTGTGCAC 50.0% identity Open · Scan
M00224_2.00 NN 70-40% CisBP CCCGCCCC 50.0% identity Open · Scan
M03686_2.00 NN 70-40% CisBP TGATTGCTCTTTT 50.0% identity Open · Scan
M04430_2.00 NN 70-40% CisBP GACCACGCCCA 50.0% identity Open · Scan
M04590_2.00 NN 70-40% CisBP TGCGCTAACCATTGC 50.0% identity Open · Scan
M06179_2.00 NN 70-40% CisBP TAAGCCTATAGA 50.0% identity Open · Scan
M07679_2.00 NN 70-40% CisBP TGCGATCTC 50.0% identity Open · Scan
M09008_2.00 NN 70-40% CisBP CCCGGCCCCACCCT 50.0% identity Open · Scan
MA0742.1 NN 70-40% JASPAR GACCACGCCCTTATT 50.0% identity Open · Scan
MA1517.1 NN 70-40% JASPAR GGCCACGCCCA 50.0% identity Open · Scan
ModCRE11
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q15776_ZKSC8_HUMAN:432:481_1llm_D_1 ModCRE Homology model GTCCGCGCGCAA Region 432-481 · 1 3D model Open · Scan
TFS_sp_Q15776_ZKSC8_HUMAN:309:358_2i13_A_1 ModCRE Homology model ATTTCTCTAAGCTT Region 309-358 · 1 3D model Open · Scan
TFS_sp_Q15776_ZKSC8_HUMAN:317:358_5v3m_C_1 ModCRE Homology model TCGTGGGGCC Region 317-358 · 1 3D model Open · Scan
TFS_sp_Q15776_ZKSC8_HUMAN:317:358_5wjq_D_1 ModCRE Homology model TCTTCGTGGG Region 317-358 · 1 3D model Open · Scan
TFS_sp_Q15776_ZKSC8_HUMAN:317:569_5wjq_D_1 ModCRE Homology model CGCCAGCCCGGGGGGGAGGGGGCCCCAG Region 317-569 · 1 3D model Open · Scan
TFS_sp_Q15776_ZKSC8_HUMAN:320:356_1ubd_C_1 ModCRE Homology model TCCCCCCCCCGGC Region 320-356 · 1 3D model Open · Scan
TFS_sp_Q15776_ZKSC8_HUMAN:320:358_2kmk_A_1 ModCRE Homology model TGCCGGGTGGGCG Region 320-358 · 1 3D model Open · Scan
TFS_sp_Q15776_ZKSC8_HUMAN:322:572_5v3j_E_1 ModCRE Homology model CCCCAAGGGGCCGGTTGCCCCGA Region 322-572 · 1 3D model Open · Scan
TFS_sp_Q15776_ZKSC8_HUMAN:322:572_5v3m_C_1 ModCRE Homology model CCGGCGTGTGGGGGGGGGGAATCC Region 322-572 · 1 3D model Open · Scan
TFS_sp_Q15776_ZKSC8_HUMAN:359:512_2i13_A_1 ModCRE Homology model AATTTAGCCCTAGTACTTTAC Region 359-512 · 1 3D model Open · Scan
TFS_sp_Q15776_ZKSC8_HUMAN:431:541_5ei9_E_1 ModCRE Homology model CCCCCGGGGGGGGGGCC Region 431-541 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 578 aa
309-572

Region 309-572 11 PWM

Residues
264 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
11 active PDBs · 6 summary rows
Templates
1LLM, 1UBD, 2I13, 2KMK, 5EI9, 5V3J, 5V3M, 5WJQ
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
11 active PDB models 6 summary rows
Region 309-57211 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_Q15776_ZKSC8_HUMAN:432:481_1llm_D_1 1llm 432-481 View model · PDB
Predicted = Low TFS_sp_Q15776_ZKSC8_HUMAN:309:358_2i13_A_1 2i13 309-358 View model · PDB
Predicted = Low TFS_sp_Q15776_ZKSC8_HUMAN:317:358_5v3m_C_1 5v3m 317-358 View model · PDB
Predicted = Low TFS_sp_Q15776_ZKSC8_HUMAN:317:358_5wjq_D_1 5wjq 317-358 View model · PDB
Predicted = Low TFS_sp_Q15776_ZKSC8_HUMAN:317:569_5wjq_D_1 5wjq 317-569 View model · PDB
Predicted = Low TFS_sp_Q15776_ZKSC8_HUMAN:320:356_1ubd_C_1 1ubd 320-356 View model · PDB
Predicted = Low TFS_sp_Q15776_ZKSC8_HUMAN:320:358_2kmk_A_1 2kmk 320-358 View model · PDB
Predicted = Low TFS_sp_Q15776_ZKSC8_HUMAN:322:572_5v3j_E_1 5v3j 322-572 View model · PDB
Predicted = Low TFS_sp_Q15776_ZKSC8_HUMAN:322:572_5v3m_C_1 5v3m 322-572 View model · PDB
Predicted = Low TFS_sp_Q15776_ZKSC8_HUMAN:359:512_2i13_A_1 2i13 359-512 View model · PDB
Predicted = Low TFS_sp_Q15776_ZKSC8_HUMAN:431:541_5ei9_E_1 5ei9 431-541 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
5 5ei9 309:572 431 541 P:E · DNA:A,B 62.2% / 75.7% 100 View · PDB TFS_sp_Q15776_ZKSC8_HUMAN:431:541_5ei9_E_1
4 2i13 309:572 359 512 P:A · DNA:C,D 59.7% / 70.1% 100 View · PDB TFS_sp_Q15776_ZKSC8_HUMAN:359:512_2i13_A_1
1 5v3m 309:572 322 572 P:C · DNA:A,B 55.0% / 69.3% 90 View · PDB TFS_sp_Q15776_ZKSC8_HUMAN:322:572_5v3m_C_1
2 5v3j 309:572 322 572 P:E · DNA:A,B 55.0% / 69.3% 90 View · PDB TFS_sp_Q15776_ZKSC8_HUMAN:322:572_5v3j_E_1
3 5wjq 309:572 317 569 P:D · DNA:A,B 53.0% / 71.1% 90 View · PDB TFS_sp_Q15776_ZKSC8_HUMAN:317:569_5wjq_D_1
1 1llm 309:572 432,432 481,481 P:C,D · DNA:A,B 48.0% / 62.0% 57,58 View · PDB DIMER_sp_Q15776_ZKSC8_HUMAN:432:481_1llm_D_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
47-132PF02023SCAN domainNo overlap with loaded model regions
222-259PF01352KRAB boxNo overlap with loaded model regions
322-344PF00096Zinc finger, C2H2 typeoverlaps 309-572
350-372PF00096Zinc finger, C2H2 typeoverlaps 309-572
378-400PF00096Zinc finger, C2H2 typeoverlaps 309-572
406-428PF00096Zinc finger, C2H2 typeoverlaps 309-572
434-456PF00096Zinc finger, C2H2 typeoverlaps 309-572
462-484PF00096Zinc finger, C2H2 typeoverlaps 309-572
490-512PF00096Zinc finger, C2H2 typeoverlaps 309-572
518-540PF00096Zinc finger, C2H2 typeoverlaps 309-572
546-568PF00096Zinc finger, C2H2 typeoverlaps 309-572