ModCRE DB

Transcription factor

Q16587 - ZNF74

Zinc finger protein 74 (Zinc finger protein 520) (hZNF7)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 644 aa

69 Generated PWM 7 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known1
MotifPredictionSourceDNA bindingSupportLogoActions
M07675_2.00 Known CisBP AACAACACTGCAATGAACATC Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)67
MotifPredictionSourceDNA bindingSupportLogoActions
M00944_2.00 NN 70-40% CisBP TCGCTATAA 63.5% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 62.3% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 62.3% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 61.1% identity Open · Scan
M08985_2.00 NN 70-40% CisBP TGAGGACCTACTGTGTGCC 60.3% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 58.8% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 58.8% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 58.8% identity Open · Scan
M08375_2.00 NN 70-40% CisBP TTCCCCATTGGCTACTGCACCGGTCCT 58.7% identity Open · Scan
M08267_2.00 NN 70-40% CisBP CAGTTTCATTTTCC 58.6% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 58.4% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 58.4% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 57.6% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 57.6% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 57.6% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 57.6% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 57.6% identity Open · Scan
M04613_2.00 NN 70-40% CisBP CTCATGTGCTAATTACAAA 57.2% identity Open · Scan
M08245_2.00 NN 70-40% CisBP TGGTGCCTTATTCCC 56.5% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 56.3% identity Open · Scan
M08334_2.00 NN 70-40% CisBP TTTGTTTTTTTCTGATTGCTTTTTACTTAT 56.2% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 56.1% identity Open · Scan
M00609_2.00 NN 70-40% CisBP GGAAGCCCTA 55.9% identity Open · Scan
M08252_2.00 NN 70-40% CisBP CCGGCTCCAGCACCC 55.7% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 55.0% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 55.0% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 55.0% identity Open · Scan
M07753_2.00 NN 70-40% CisBP TGCATTCCTTGGCTTGTG 54.1% identity Open · Scan
M07678_2.00 NN 70-40% CisBP CCCGCCCCCTCCTCCCCCTTCCCACCC 54.0% identity Open · Scan
M07747_2.00 NN 70-40% CisBP TGGTCTATAAAGGGCCTGGTT 54.0% identity Open · Scan
M04515_2.00 NN 70-40% CisBP TATGCTATAACAAGCAGCCCC 53.5% identity Open · Scan
M07581_2.00 NN 70-40% CisBP TCCCCTGTGCTTCTCTCCCCT 53.5% identity Open · Scan
M07754_2.00 NN 70-40% CisBP CGCCCCCTCCCT 52.9% identity Open · Scan
M04465_2.00 NN 70-40% CisBP GTGATTCTTATCTTATCCTT 52.6% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 52.6% identity Open · Scan
M07657_2.00 NN 70-40% CisBP CCCCTGCATGTCCCCATTTTT 52.6% identity Open · Scan
M08335_2.00 NN 70-40% CisBP AGTCGTTGTCTG 52.6% identity Open · Scan
M07618_2.00 NN 70-40% CisBP CCTTTGGTGCTC 52.5% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 52.2% identity Open · Scan
M01456_2.00 NN 70-40% CisBP GTGATCGGCG 52.1% identity Open · Scan
M07562_2.00 NN 70-40% CisBP GAAAAAAAC 52.1% identity Open · Scan
M07587_2.00 NN 70-40% CisBP CCCCCTCCCCAGTCGAGCCCCCGC 52.1% identity Open · Scan
M07683_2.00 NN 70-40% CisBP GTGGGAAAGCCT 52.1% identity Open · Scan
MA1601.1 NN 70-40% JASPAR ATGTGGGAAA 52.1% identity Open · Scan
M07610_2.00 NN 70-40% CisBP CCTTCTTCCTCCCCCCTGCCCACC 51.9% identity Open · Scan
M07723_2.00 NN 70-40% CisBP CCGCTGCTCCCTGCT 51.9% identity Open · Scan
M04621_2.00 NN 70-40% CisBP AGCAATTCCGCTCA 51.5% identity Open · Scan
M03671_2.00 NN 70-40% CisBP ATTACCATACAAGTGCAC 51.2% identity Open · Scan
MA1656.1 NN 70-40% JASPAR CCAAGCCCAACCAG 51.2% identity Open · Scan
M06112_2.00 NN 70-40% CisBP CTACTTTCACCGGGG 51.0% identity Open · Scan
M08314_2.00 NN 70-40% CisBP ATTCATCAAGGTCCTCAACAATGG 51.0% identity Open · Scan
M08901_2.00 NN 70-40% CisBP CCAGTTCACACC 51.0% identity Open · Scan
M01474_2.00 NN 70-40% CisBP CGCCGATCAC 50.9% identity Open · Scan
M08395_2.00 NN 70-40% CisBP GCTGCCTACTCTTCC 50.9% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 50.7% identity Open · Scan
M07600_2.00 NN 70-40% CisBP GCATTAGC 50.7% identity Open · Scan
M07633_2.00 NN 70-40% CisBP CTCTCGTTGTGCCTTTGCCAT 50.7% identity Open · Scan
M08373_2.00 NN 70-40% CisBP CCCCCTGGCTCTTCCTCT 50.6% identity Open · Scan
M04536_2.00 NN 70-40% CisBP ACGTAACCCGATACC 50.5% identity Open · Scan
M08311_2.00 NN 70-40% CisBP CTGGAACAGAAGGGGCGA 50.5% identity Open · Scan
M07588_2.00 NN 70-40% CisBP TCCTTCCCTCTTTCC 50.4% identity Open · Scan
MA1602.1 NN 70-40% JASPAR CGTCTACACGGG 50.4% identity Open · Scan
M08247_2.00 NN 70-40% CisBP AAAAATAACAAACGG 50.3% identity Open · Scan
MA1154.1 NN 70-40% JASPAR CTTTCCCACAACACGAC 50.2% identity Open · Scan
M07660_2.00 NN 70-40% CisBP CCGCGCCTACCTGAGGGCGCGGGCCTGGGG 50.1% identity Open · Scan
M00786_2.00 NN 70-40% CisBP TATATATAT 50.0% identity Open · Scan
M07628_2.00 NN 70-40% CisBP AGTGGTTCTGCTTCT 50.0% identity Open · Scan
ModCRE1
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_sp_Q16587_ZNF74_HUMAN:357:467_5ei9_E_1 ModCRE Homology model CCCCCGGGGGGCGCCCG Region 357-467 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 644 aa
245-579

Region 245-579 1 PWM

Residues
335 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
7 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
7 active PDB models 6 summary rows
Region 245-5797 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_Q16587_ZNF74_HUMAN:330:381_1llm_D_1 1llm 330-381 View model · PDB
Predicted = Low TFS_sp_Q16587_ZNF74_HUMAN:245:523_5wjq_D_1 5wjq 245-523 View model · PDB
Predicted = Low TFS_sp_Q16587_ZNF74_HUMAN:248:546_7w1m_H_1 7w1m 248-546 View model · PDB
Predicted = Low TFS_sp_Q16587_ZNF74_HUMAN:303:579_5v3j_E_1 5v3j 303-579 View model · PDB
Predicted = Low TFS_sp_Q16587_ZNF74_HUMAN:303:579_5v3m_C_1 5v3m 303-579 View model · PDB
Predicted = Low TFS_sp_Q16587_ZNF74_HUMAN:357:467_5ei9_E_1 5ei9 357-467 View model · PDB
Predicted = Low TFS_sp_Q16587_ZNF74_HUMAN:397:550_2i13_A_1 2i13 397-550 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 2i13 245:579 397 550 P:A · DNA:C,D 53.9% / 69.5% 100 View · PDB TFS_sp_Q16587_ZNF74_HUMAN:397:550_2i13_A_1
3 5wjq 245:579 245 523 P:D · DNA:A,B 51.6% / 66.7% 99 View · PDB TFS_sp_Q16587_ZNF74_HUMAN:245:523_5wjq_D_1
1 5v3m 245:579 303 579 P:C · DNA:A,B 50.5% / 71.1% 100 View · PDB TFS_sp_Q16587_ZNF74_HUMAN:303:579_5v3m_C_1
2 5v3j 245:579 303 579 P:E · DNA:A,B 50.5% / 71.1% 100 View · PDB TFS_sp_Q16587_ZNF74_HUMAN:303:579_5v3j_E_1
1 1llm 245:579 330,330 381,381 P:C,D · DNA:A,B 42.3% / 59.6% 59,61 View · PDB DIMER_sp_Q16587_ZNF74_HUMAN:330:381_1llm_D_1
5 7w1m 245:579 248 546 P:H · DNA:F,G 36.0% / 51.3% 92 View · PDB TFS_sp_Q16587_ZNF74_HUMAN:248:546_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
42-83PF01352KRAB boxNo overlap with loaded model regions
248-270PF00096Zinc finger, C2H2 typeoverlaps 245-579
276-298PF00096Zinc finger, C2H2 typeoverlaps 245-579
304-326PF00096Zinc finger, C2H2 typeoverlaps 245-579
360-382PF00096Zinc finger, C2H2 typeoverlaps 245-579
416-438PF00096Zinc finger, C2H2 typeoverlaps 245-579
472-494PF00096Zinc finger, C2H2 typeoverlaps 245-579
528-550PF00096Zinc finger, C2H2 typeoverlaps 245-579
556-578PF00096Zinc finger, C2H2 typeoverlaps 245-579