ModCRE DB

Transcription factor

Q17RH7 - TPRXL

Tetra-peptide repeat homeobox-like protein

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 139 aa

63 Generated PWM 16 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)53
MotifPredictionSourceDNA bindingSupportLogoActions
M00424_2.00 NN 70-40% CisBP ACTAATTA 60.0% identity Open · Scan
M03814_2.00 NN 70-40% CisBP GTAATGGC 57.1% identity Open · Scan
MA0648.1 NN 70-40% JASPAR GCTAATCCCC 56.1% identity Open · Scan
M01249_2.00 NN 70-40% CisBP CCCCTAAT 55.8% identity Open · Scan
M02143_2.00 NN 70-40% CisBP TTAATTGG 55.0% identity Open · Scan
MA0644.1 NN 70-40% JASPAR ACCAATTAAC 54.0% identity Open · Scan
M02123_2.00 NN 70-40% CisBP TTAATCCCT 53.9% identity Open · Scan
MA0719.1 NN 70-40% JASPAR ATAATCCC 52.9% identity Open · Scan
MA0629.1 NN 70-40% JASPAR AAGACGCTGTAAAGCGA 52.7% identity Open · Scan
MA0075.1 NN 70-40% JASPAR AATTA 52.6% identity Open · Scan
MA0075.3 NN 70-40% JASPAR CTAATTAA 52.6% identity Open · Scan
M03076_2.00 NN 70-40% CisBP TTAATTAAATTAA 52.5% identity Open · Scan
MA0874.1 NN 70-40% JASPAR GTCCATTAATTAATGGA 52.5% identity Open · Scan
MA1481.1 NN 70-40% JASPAR CTAATTAC 52.5% identity Open · Scan
M00440_2.00 NN 70-40% CisBP TTAATCCC 52.2% identity Open · Scan
MA1547.1 NN 70-40% JASPAR ATAATCCC 52.2% identity Open · Scan
M02195_2.00 NN 70-40% CisBP CCTAATCCGC 51.8% identity Open · Scan
M06326_2.00 NN 70-40% CisBP TTAATT 51.7% identity Open · Scan
M09153_2.00 NN 70-40% CisBP GTTAATCCCCT 51.7% identity Open · Scan
MA0894.1 NN 70-40% JASPAR GCTAATTGGC 51.7% identity Open · Scan
M03250_2.00 NN 70-40% CisBP TTAATCCG 50.8% identity Open · Scan
M09681_2.00 NN 70-40% CisBP CTAATCCG 50.8% identity Open · Scan
MA0681.1 NN 70-40% JASPAR TAATTTAATTA 50.8% identity Open · Scan
MA0711.1 NN 70-40% JASPAR TTAATCCG 50.8% identity Open · Scan
MA0712.1 NN 70-40% JASPAR TTAATCCT 50.8% identity Open · Scan
MA0713.1 NN 70-40% JASPAR TAATTTAATTA 50.8% identity Open · Scan
MA0891.1 NN 70-40% JASPAR CCTAATCCGC 50.7% identity Open · Scan
M00349_2.00 NN 70-40% CisBP CTAATTAGC 50.0% identity Open · Scan
M00410_2.00 NN 70-40% CisBP TTTTATGACC 50.0% identity Open · Scan
M01241_2.00 NN 70-40% CisBP TTAATCCC 50.0% identity Open · Scan
M02082_2.00 NN 70-40% CisBP ATTGTACAAT 50.0% identity Open · Scan
M02111_2.00 NN 70-40% CisBP GTTAATTAG 50.0% identity Open · Scan
M03204_2.00 NN 70-40% CisBP TTAATTGG 50.0% identity Open · Scan
M03236_2.00 NN 70-40% CisBP GTTAATCCGC 50.0% identity Open · Scan
M03828_2.00 NN 70-40% CisBP GTTAATTAACGTTAATTAAC 50.0% identity Open · Scan
M03876_2.00 NN 70-40% CisBP TAATTAAATTA 50.0% identity Open · Scan
M05105_2.00 NN 70-40% CisBP GTCGTAAAAT 50.0% identity Open · Scan
M05133_2.00 NN 70-40% CisBP CTAATCCC 50.0% identity Open · Scan
M05367_2.00 NN 70-40% CisBP TTAATTAG 50.0% identity Open · Scan
M09208_2.00 NN 70-40% CisBP CCTAATCCTCTTA 50.0% identity Open · Scan
M09569_2.00 NN 70-40% CisBP GTTAATCCCT 50.0% identity Open · Scan
MA0068.2 NN 70-40% JASPAR CTAATTAG 50.0% identity Open · Scan
MA0467.1 NN 70-40% JASPAR AAGAGGATTAG 50.0% identity Open · Scan
MA0485.1 NN 70-40% JASPAR GGCCATAAATCAC 50.0% identity Open · Scan
MA0485.2 NN 70-40% JASPAR GTCGTAAAAT 50.0% identity Open · Scan
MA0630.1 NN 70-40% JASPAR TTAATTGG 50.0% identity Open · Scan
MA0720.1 NN 70-40% JASPAR CTAATTAA 50.0% identity Open · Scan
MA0721.1 NN 70-40% JASPAR CTAATTAA 50.0% identity Open · Scan
MA0725.1 NN 70-40% JASPAR CTAATTAT 50.0% identity Open · Scan
MA0883.1 NN 70-40% JASPAR TGAACCGGATTAATGAA 50.0% identity Open · Scan
MA0913.1 NN 70-40% JASPAR GCAATAAAAA 50.0% identity Open · Scan
MA0913.2 NN 70-40% JASPAR GCAATAAAAC 50.0% identity Open · Scan
MA1503.1 NN 70-40% JASPAR GTCGTAAAAT 50.0% identity Open · Scan
ModCRE10
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q17RH7_TPRXL_HUMAN:19:78_1fjl_A_1 ModCRE Homology model TTTATCCGATTAA Region 19-78 · 1 3D model Open · Scan
DIMER_sp_Q17RH7_TPRXL_HUMAN:21:74_2hdd_B_1 ModCRE Homology model CAAAATTAATTGGTTAA Region 21-74 · 1 3D model Open · Scan
DIMER_sp_Q17RH7_TPRXL_HUMAN:21:74_6a8r_B_1 ModCRE Homology model CAATTCCCGG Region 21-74 · 1 3D model Open · Scan
DIMER_sp_Q17RH7_TPRXL_HUMAN:24:74_5z2t_D_1 ModCRE Homology model TCCATTCCATCCC Region 24-74 · 1 3D model Open · Scan
DIMER_sp_Q17RH7_TPRXL_HUMAN:24:74_6dfy_C_1 ModCRE Homology model AATCCCATTGC Region 24-74 · 1 3D model Open · Scan
TFS_sp_Q17RH7_TPRXL_HUMAN:19:77_2me6_A_1 ModCRE Homology model TACTCAATTTTTAT Region 19-77 · 1 3D model Open · Scan
TFS_sp_Q17RH7_TPRXL_HUMAN:21:74_6a8r_B_1 ModCRE Homology model CCATTCCCGC Region 21-74 · 1 3D model Open · Scan
TFS_sp_Q17RH7_TPRXL_HUMAN:21:77_1ig7_A_1 ModCRE Homology model GATTAATTGCCCC Region 21-77 · 1 3D model Open · Scan
TFS_sp_Q17RH7_TPRXL_HUMAN:24:74_5z2t_D_1 ModCRE Homology model CCAATTCCATCCC Region 24-74 · 1 3D model Open · Scan
TFS_sp_Q17RH7_TPRXL_HUMAN:24:74_6dfy_C_1 ModCRE Homology model AATTCCATTGC Region 24-74 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 139 aa
9-80

Region 9-80 10 PWM

Residues
72 aa
Domains
PF00046 · Homeodomain
3D models
16 active PDBs · 10 summary rows
Templates
1FJL, 1IG7, 2HDD, 2LKX, 2ME6, 3A01, 3CMY, 3LNQ, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
16 active PDB models 10 summary rows
Region 9-8016 models · 10 summary rows
Actions
Predicted = Low DIMER_sp_Q17RH7_TPRXL_HUMAN:19:78_1fjl_A_1 1fjl 19-78 View model · PDB
Predicted = Low DIMER_sp_Q17RH7_TPRXL_HUMAN:21:74_2hdd_B_1 2hdd 21-74 View model · PDB
Predicted = Low DIMER_sp_Q17RH7_TPRXL_HUMAN:21:74_3a01_B_1 3a01 21-74 View model · PDB
Predicted = Low DIMER_sp_Q17RH7_TPRXL_HUMAN:21:74_6a8r_B_1 6a8r 21-74 View model · PDB
Predicted = Low DIMER_sp_Q17RH7_TPRXL_HUMAN:24:74_5z2t_D_1 5z2t 24-74 View model · PDB
Predicted = Low DIMER_sp_Q17RH7_TPRXL_HUMAN:24:74_6dfy_C_1 6dfy 24-74 View model · PDB
Predicted = Low TFS_sp_Q17RH7_TPRXL_HUMAN:19:77_2me6_A_1 2me6 19-77 View model · PDB
Predicted = Low TFS_sp_Q17RH7_TPRXL_HUMAN:19:78_1fjl_A_1 1fjl 19-78 View model · PDB
Predicted = Low TFS_sp_Q17RH7_TPRXL_HUMAN:20:74_3cmy_A_1 3cmy 20-74 View model · PDB
Predicted = Low TFS_sp_Q17RH7_TPRXL_HUMAN:20:80_2lkx_A_1 2lkx 20-80 View model · PDB
Predicted = Low TFS_sp_Q17RH7_TPRXL_HUMAN:21:74_3a01_B_1 3a01 21-74 View model · PDB
Predicted = Low TFS_sp_Q17RH7_TPRXL_HUMAN:21:74_6a8r_B_1 6a8r 21-74 View model · PDB
Predicted = Low TFS_sp_Q17RH7_TPRXL_HUMAN:21:77_1ig7_A_1 1ig7 21-77 View model · PDB
Predicted = Low TFS_sp_Q17RH7_TPRXL_HUMAN:24:74_3lnq_A_1 3lnq 24-74 View model · PDB
Predicted = Low TFS_sp_Q17RH7_TPRXL_HUMAN:24:74_5z2t_D_1 5z2t 24-74 View model · PDB
Predicted = Low TFS_sp_Q17RH7_TPRXL_HUMAN:24:74_6dfy_C_1 6dfy 24-74 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
5 3lnq 13:90 24 74 P:A · DNA:B,C 51.0% / 62.7% 87 View · PDB TFS_sp_Q17RH7_TPRXL_HUMAN:24:74_3lnq_A_1
2 3cmy 13:90 20 74 P:A · DNA:B,C 50.9% / 65.5% 91 View · PDB TFS_sp_Q17RH7_TPRXL_HUMAN:20:74_3cmy_A_1
3 2lkx 13:90 20 80 P:A · DNA:B,C 50.0% / 67.7% 89 View · PDB TFS_sp_Q17RH7_TPRXL_HUMAN:20:80_2lkx_A_1
2 3a01 13:90 9,21 78,74 P:A,B · DNA:C,D 50.0% / 63.0% 89,94 View · PDB DIMER_sp_Q17RH7_TPRXL_HUMAN:21:74_3a01_B_1
4 3a01 13:90 9,21 78,74 P:A,B · DNA:C,D 50.0% / 63.0% 89,94 View · PDB TFS_sp_Q17RH7_TPRXL_HUMAN:21:74_3a01_B_1
1 1fjl 13:90 19,20 78,74 P:A,B · DNA:D,E 46.7% / 70.0% 92,96 View · PDB DIMER_sp_Q17RH7_TPRXL_HUMAN:19:78_1fjl_A_1
1 1fjl 13:90 19,20 78,74 P:A,B · DNA:D,E 46.7% / 70.0% 92,96 View · PDB TFS_sp_Q17RH7_TPRXL_HUMAN:19:78_1fjl_A_1
5 2hdd 13:90 24,21 74,74 P:A,B · DNA:C,D 38.9% / 63.0% 92,96 View · PDB DIMER_sp_Q17RH7_TPRXL_HUMAN:21:74_2hdd_B_1
3 6dfy 13:90 24,25 74,74 P:C,D · DNA:E,F 37.3% / 60.8% 94,96 View · PDB DIMER_sp_Q17RH7_TPRXL_HUMAN:24:74_6dfy_C_1
4 5z2t 13:90 24,24 74,74 P:C,D · DNA:E,F 37.3% / 60.8% 96,94 View · PDB DIMER_sp_Q17RH7_TPRXL_HUMAN:24:74_5z2t_D_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
21-75PF00046Homeodomainoverlaps 9-80