Transcription factor

Q3SXZ3 - ZNF718

Zinc finger protein 718

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 478 aa

78 Generated PWM 7 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)72

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M07586_2.00	NN 70-40%	CisBP	GGGACCCGGGTGGGGGCGTCCCCC	68.6% identity		Open · Scan
M07715_2.00	NN 70-40%	CisBP	CCGCCGCCGCCGTGG	64.3% identity		Open · Scan
M00955_2.00	NN 70-40%	CisBP	ACGTCCTCT	63.5% identity		Open · Scan
M08985_2.00	NN 70-40%	CisBP	TGAGGACCTACTGTGTGCC	63.2% identity		Open · Scan
M07687_2.00	NN 70-40%	CisBP	ACAAATAAGGTTCTTGTGCCCCCTGCT	63.0% identity		Open · Scan
M07761_2.00	NN 70-40%	CisBP	CTGATTATTCACCCA	61.9% identity		Open · Scan
M08934_2.00	NN 70-40%	CisBP	GCTGTACCTGCTTATTAGGC	61.9% identity		Open · Scan
M07775_2.00	NN 70-40%	CisBP	GCCGAAACCCGGG	61.2% identity		Open · Scan
M08921_2.00	NN 70-40%	CisBP	CCTCATTCTTCTTGGACATG	60.1% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	60.0% identity		Open · Scan
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	60.0% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	60.0% identity		Open · Scan
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	60.0% identity		Open · Scan
M08381_2.00	NN 70-40%	CisBP	ACATTTTGTCCTCCTAGTCCT	59.6% identity		Open · Scan
M08295_2.00	NN 70-40%	CisBP	CTGCTGGAATCTCCA	59.5% identity		Open · Scan
MA1599.1	NN 70-40%	JASPAR	CGGGCCAAGCCCCTAT	59.2% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	58.8% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	58.8% identity		Open · Scan
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	58.8% identity		Open · Scan
M07565_2.00	NN 70-40%	CisBP	CCTCTGGGGGCTCGTCCA	58.1% identity		Open · Scan
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	57.6% identity		Open · Scan
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	57.6% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	57.6% identity		Open · Scan
M00945_2.00	NN 70-40%	CisBP	CACCGCAC	56.9% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	56.6% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	56.4% identity		Open · Scan
M00782_2.00	NN 70-40%	CisBP	AGTGTGCGCTA	55.9% identity		Open · Scan
M08355_2.00	NN 70-40%	CisBP	GCGAACTCCTATTCATCC	55.9% identity		Open · Scan
M08395_2.00	NN 70-40%	CisBP	GCTGCCTACTCTTCC	55.6% identity		Open · Scan
M07714_2.00	NN 70-40%	CisBP	AGCCCATTGGGGCCTATGCCC	55.2% identity		Open · Scan
M04465_2.00	NN 70-40%	CisBP	GTGATTCTTATCTTATCCTT	55.1% identity		Open · Scan
M07605_2.00	NN 70-40%	CisBP	TATTTTTTTTTATTTTTTTTTTTTTTTTTT	55.1% identity		Open · Scan
M07638_2.00	NN 70-40%	CisBP	TGCAGCTCCCTGCCC	54.7% identity		Open · Scan
M07767_2.00	NN 70-40%	CisBP	AAAAACCCCAGA	54.7% identity		Open · Scan
M08335_2.00	NN 70-40%	CisBP	AGTCGTTGTCTG	54.3% identity		Open · Scan
MA1124.1	NN 70-40%	JASPAR	CATTCATTCATTC	54.1% identity		Open · Scan
M04598_2.00	NN 70-40%	CisBP	CGCTAACTCTCCACA	53.9% identity		Open · Scan
M08245_2.00	NN 70-40%	CisBP	TGGTGCCTTATTCCC	53.9% identity		Open · Scan
M04650_2.00	NN 70-40%	CisBP	GCATAACTGCCCCGCTGCC	53.5% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	53.5% identity		Open · Scan
M08292_2.00	NN 70-40%	CisBP	TGTATTCCTTGTCATGTGTGG	53.3% identity		Open · Scan
M07678_2.00	NN 70-40%	CisBP	CCCGCCCCCTCCTCCCCCTTCCCACCC	53.2% identity		Open · Scan
M06112_2.00	NN 70-40%	CisBP	CTACTTTCACCGGGG	53.1% identity		Open · Scan
M07683_2.00	NN 70-40%	CisBP	GTGGGAAAGCCT	53.1% identity		Open · Scan
MA1601.1	NN 70-40%	JASPAR	ATGTGGGAAA	53.1% identity		Open · Scan
M04515_2.00	NN 70-40%	CisBP	TATGCTATAACAAGCAGCCCC	53.0% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	52.9% identity		Open · Scan
M07753_2.00	NN 70-40%	CisBP	TGCATTCCTTGGCTTGTG	52.7% identity		Open · Scan
M07562_2.00	NN 70-40%	CisBP	GAAAAAAAC	52.4% identity		Open · Scan
MA1602.1	NN 70-40%	JASPAR	CGTCTACACGGG	52.3% identity		Open · Scan
M08325_2.00	NN 70-40%	CisBP	TTTTTTTTT	52.2% identity		Open · Scan
M08263_2.00	NN 70-40%	CisBP	ATCTCGGCACTTTGGGAGGCCA	52.0% identity		Open · Scan
M07581_2.00	NN 70-40%	CisBP	TCCCCTGTGCTTCTCTCCCCT	51.9% identity		Open · Scan
M08267_2.00	NN 70-40%	CisBP	CAGTTTCATTTTCC	51.9% identity		Open · Scan
M08373_2.00	NN 70-40%	CisBP	CCCCCTGGCTCTTCCTCT	51.7% identity		Open · Scan
M01181_2.00	NN 70-40%	CisBP	GCGCATCCCC	51.6% identity		Open · Scan
M07578_2.00	NN 70-40%	CisBP	CAACTCTCC	51.1% identity		Open · Scan
M00142_2.00	NN 70-40%	CisBP	GTGCTCCT	51.0% identity		Open · Scan
M07649_2.00	NN 70-40%	CisBP	CCCCCCCCCCCCTCAGGAATGCC	51.0% identity		Open · Scan
M00609_2.00	NN 70-40%	CisBP	GGAAGCCCTA	50.4% identity		Open · Scan
M07712_2.00	NN 70-40%	CisBP	ACATTTTTTTAATCTAAAAAAACATTTACA	50.4% identity		Open · Scan
M08254_2.00	NN 70-40%	CisBP	CTGCCCTGGGACTTT	50.4% identity		Open · Scan
M01044_2.00	NN 70-40%	CisBP	TCTCTCTTTC	50.3% identity		Open · Scan
M08234_2.00	NN 70-40%	CisBP	GTCAACTTGACTGGGCCA	50.3% identity		Open · Scan
M07777_2.00	NN 70-40%	CisBP	GCCAATTTCCGTGGTGTAAAT	50.1% identity		Open · Scan
M00779_2.00	NN 70-40%	CisBP	GCCACGCCCA	50.0% identity		Open · Scan
M01442_2.00	NN 70-40%	CisBP	ACCCCACATT	50.0% identity		Open · Scan
M04430_2.00	NN 70-40%	CisBP	GACCACGCCCA	50.0% identity		Open · Scan
M07660_2.00	NN 70-40%	CisBP	CCGCGCCTACCTGAGGGCGCGGGCCTGGGG	50.0% identity		Open · Scan
M08314_2.00	NN 70-40%	CisBP	ATTCATCAAGGTCCTCAACAATGG	50.0% identity		Open · Scan
M08867_2.00	NN 70-40%	CisBP	CACCCCCTG	50.0% identity		Open · Scan
MA0742.1	NN 70-40%	JASPAR	GACCACGCCCTTATT	50.0% identity		Open · Scan

ModCRE6

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
DIMER_sp_Q3SXZ3_ZN718_HUMAN:337:388_1llm_D_1	ModCRE	Homology model	CCCGGGCCCGGA	Region 337-388 · 1 3D model		Open · Scan
TFS_sp_Q3SXZ3_ZN718_HUMAN:172:446_5v3j_E_1	ModCRE	Homology model	TTCACCGGGACCCTGGGGGAATTTAA	Region 172-446 · 1 3D model		Open · Scan
TFS_sp_Q3SXZ3_ZN718_HUMAN:172:446_5v3m_C_1	ModCRE	Homology model	CGGCCCACCCCCCCCCCCTTCTCCCC	Region 172-446 · 1 3D model		Open · Scan
TFS_sp_Q3SXZ3_ZN718_HUMAN:196:474_5wjq_D_1	ModCRE	Homology model	GGGTCCTTCCCCCCCCGTTCATTCCCCC	Region 196-474 · 1 3D model		Open · Scan
TFS_sp_Q3SXZ3_ZN718_HUMAN:236:389_2i13_A_1	ModCRE	Homology model	CTTCAAATTCTTCTATATAAA	Region 236-389 · 1 3D model		Open · Scan
TFS_sp_Q3SXZ3_ZN718_HUMAN:336:446_5ei9_E_1	ModCRE	Homology model	ACGGGAGCCCGGCCGGC	Region 336-446 · 1 3D model		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 478 aa

170-474

Region 170-474 6 PWM

Residues

305 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

7 active PDBs · 6 summary rows

Templates

1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ, 7W1M

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

7 active PDB models 6 summary rows

Region 170-4747 models · 6 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_sp_Q3SXZ3_ZN718_HUMAN:337:388_1llm_D_1	1llm	337-388	View model · PDB
Predicted = Low	TFS_sp_Q3SXZ3_ZN718_HUMAN:170:469_7w1m_H_1	7w1m	170-469	View model · PDB
Predicted = Low	TFS_sp_Q3SXZ3_ZN718_HUMAN:172:446_5v3j_E_1	5v3j	172-446	View model · PDB
Predicted = Low	TFS_sp_Q3SXZ3_ZN718_HUMAN:172:446_5v3m_C_1	5v3m	172-446	View model · PDB
Predicted = Low	TFS_sp_Q3SXZ3_ZN718_HUMAN:196:474_5wjq_D_1	5wjq	196-474	View model · PDB
Predicted = Low	TFS_sp_Q3SXZ3_ZN718_HUMAN:236:389_2i13_A_1	2i13	236-389	View model · PDB
Predicted = Low	TFS_sp_Q3SXZ3_ZN718_HUMAN:336:446_5ei9_E_1	5ei9	336-446	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
4	2i13	170:474	236	389	P:A · DNA:C,D	53.9% / 68.8%	100	View · PDB TFS_sp_Q3SXZ3_ZN718_HUMAN:236:389_2i13_A_1
2	5v3m	170:474	172	446	P:C · DNA:A,B	50.2% / 72.4%	99	View · PDB TFS_sp_Q3SXZ3_ZN718_HUMAN:172:446_5v3m_C_1
3	5v3j	170:474	172	446	P:E · DNA:A,B	50.2% / 72.4%	99	View · PDB TFS_sp_Q3SXZ3_ZN718_HUMAN:172:446_5v3j_E_1
1	5wjq	170:474	196	474	P:D · DNA:A,B	50.2% / 72.0%	99	View · PDB TFS_sp_Q3SXZ3_ZN718_HUMAN:196:474_5wjq_D_1
1	1llm	170:474	337,337	388,388	P:C,D · DNA:A,B	48.1% / 65.4%	59,61	View · PDB DIMER_sp_Q3SXZ3_ZN718_HUMAN:337:388_1llm_D_1
5	7w1m	170:474	170	469	P:H · DNA:F,G	32.7% / 48.2%	93	View · PDB TFS_sp_Q3SXZ3_ZN718_HUMAN:170:469_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
4-44	PF01352	KRAB box	No overlap with loaded model regions
171-193	PF00096	Zinc finger, C2H2 type	overlaps 170-474
199-221	PF00096	Zinc finger, C2H2 type	overlaps 170-474
227-249	PF00096	Zinc finger, C2H2 type	overlaps 170-474
255-277	PF00096	Zinc finger, C2H2 type	overlaps 170-474
283-305	PF00096	Zinc finger, C2H2 type	overlaps 170-474
311-333	PF00096	Zinc finger, C2H2 type	overlaps 170-474
339-361	PF00096	Zinc finger, C2H2 type	overlaps 170-474
367-389	PF00096	Zinc finger, C2H2 type	overlaps 170-474
395-417	PF00096	Zinc finger, C2H2 type	overlaps 170-474
423-445	PF00096	Zinc finger, C2H2 type	overlaps 170-474
451-473	PF00096	Zinc finger, C2H2 type	overlaps 170-474