ModCRE DB

Transcription factor

Q494X3 - ZNF404

Zinc finger protein 404

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 552 aa

57 Generated PWM 7 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)52
MotifPredictionSourceDNA bindingSupportLogoActions
M00939_2.00 NN 70-40% CisBP CCACCTCA 65.0% identity Open · Scan
M04653_2.00 NN 70-40% CisBP GGTACGGTTGTCCATGTTGCAA 64.1% identity Open · Scan
M08985_2.00 NN 70-40% CisBP TGAGGACCTACTGTGTGCC 60.9% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 60.0% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 58.8% identity Open · Scan
M06084_2.00 NN 70-40% CisBP AGACCACCCAC 58.0% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 57.6% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 57.5% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 57.3% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 57.1% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 56.9% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 56.6% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 56.4% identity Open · Scan
M08347_2.00 NN 70-40% CisBP GCCCTGGGCAGC 56.4% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 55.9% identity Open · Scan
MA1587.1 NN 70-40% JASPAR CCTCGACCTCCTGA 55.7% identity Open · Scan
M08267_2.00 NN 70-40% CisBP CAGTTTCATTTTCC 55.6% identity Open · Scan
M08375_2.00 NN 70-40% CisBP TTCCCCATTGGCTACTGCACCGGTCCT 54.5% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 54.3% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 54.3% identity Open · Scan
M07693_2.00 NN 70-40% CisBP CTCCTGTGTGTGCCTTGGCTG 54.0% identity Open · Scan
M07753_2.00 NN 70-40% CisBP TGCATTCCTTGGCTTGTG 53.8% identity Open · Scan
M04621_2.00 NN 70-40% CisBP AGCAATTCCGCTCA 53.6% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 53.0% identity Open · Scan
M08263_2.00 NN 70-40% CisBP ATCTCGGCACTTTGGGAGGCCA 53.0% identity Open · Scan
M07638_2.00 NN 70-40% CisBP TGCAGCTCCCTGCCC 52.9% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 52.8% identity Open · Scan
M08254_2.00 NN 70-40% CisBP CTGCCCTGGGACTTT 52.8% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 52.8% identity Open · Scan
M08371_2.00 NN 70-40% CisBP CCAGACTTGTCCTCT 52.6% identity Open · Scan
M07581_2.00 NN 70-40% CisBP TCCCCTGTGCTTCTCTCCCCT 52.5% identity Open · Scan
M08309_2.00 NN 70-40% CisBP AAAAACCCCCCTGCAGAGCCCAGCCCT 52.3% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 52.3% identity Open · Scan
M07648_2.00 NN 70-40% CisBP GCTTGCAAAAAAAATTTAACTCCCAGCTC 52.2% identity Open · Scan
M07727_2.00 NN 70-40% CisBP CGCCGCCTCCCC 52.2% identity Open · Scan
MA1596.1 NN 70-40% JASPAR GCCTCAGCCTCCCGAG 52.2% identity Open · Scan
M04613_2.00 NN 70-40% CisBP CTCATGTGCTAATTACAAA 52.1% identity Open · Scan
M07658_2.00 NN 70-40% CisBP CCGCCGCAGCCGCCG 52.1% identity Open · Scan
M08860_2.00 NN 70-40% CisBP TCTTATAAGGGCACTAATCCCATT 52.0% identity Open · Scan
M08949_2.00 NN 70-40% CisBP TTCTATTTCTTCTTGTGTCA 52.0% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 51.7% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 51.7% identity Open · Scan
M08334_2.00 NN 70-40% CisBP TTTGTTTTTTTCTGATTGCTTTTTACTTAT 51.5% identity Open · Scan
M08245_2.00 NN 70-40% CisBP TGGTGCCTTATTCCC 51.4% identity Open · Scan
M08395_2.00 NN 70-40% CisBP GCTGCCTACTCTTCC 51.2% identity Open · Scan
M07566_2.00 NN 70-40% CisBP TCAAACCATCCTTGC 51.1% identity Open · Scan
M04465_2.00 NN 70-40% CisBP GTGATTCTTATCTTATCCTT 51.0% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 50.9% identity Open · Scan
M07587_2.00 NN 70-40% CisBP CCCCCTCCCCAGTCGAGCCCCCGC 50.8% identity Open · Scan
M07598_2.00 NN 70-40% CisBP CTGACAATACCAAGTGTTGAC 50.6% identity Open · Scan
M08367_2.00 NN 70-40% CisBP GGGGTGATGACCACTCTGGCTTCTTAC 50.5% identity Open · Scan
M07588_2.00 NN 70-40% CisBP TCCTTCCCTCTTTCC 50.3% identity Open · Scan
ModCRE5
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_sp_Q494X3_ZN404_HUMAN:242:518_5v3j_E_1 ModCRE Homology model CGAGGCCCCCGGGTCGGGGCCCCCGG Region 242-518 · 1 3D model Open · Scan
TFS_sp_Q494X3_ZN404_HUMAN:242:518_5v3m_C_1 ModCRE Homology model GCGGGGGGGCCCTCGAAAACGTTACG Region 242-518 · 1 3D model Open · Scan
TFS_sp_Q494X3_ZN404_HUMAN:269:545_5wjq_D_1 ModCRE Homology model CCGCGGGGGGGCCGGGGAAAACTATTTG Region 269-545 · 1 3D model Open · Scan
TFS_sp_Q494X3_ZN404_HUMAN:392:545_2i13_A_1 ModCRE Homology model CTAGCGCTAGAGGTAGGCTTT Region 392-545 · 1 3D model Open · Scan
TFS_sp_Q494X3_ZN404_HUMAN:409:518_5ei9_E_1 ModCRE Homology model CCCGGGGGGGGGGGCAC Region 409-518 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 552 aa
242-546

Region 242-546 5 PWM

Residues
305 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF13912 · C2H2-type zinc finger PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
7 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
7 active PDB models 6 summary rows
Region 242-5467 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_Q494X3_ZN404_HUMAN:493:546_1llm_C_1 1llm 493-546 View model · PDB
Predicted = Low TFS_sp_Q494X3_ZN404_HUMAN:242:518_5v3j_E_1 5v3j 242-518 View model · PDB
Predicted = Low TFS_sp_Q494X3_ZN404_HUMAN:242:518_5v3m_C_1 5v3m 242-518 View model · PDB
Predicted = Low TFS_sp_Q494X3_ZN404_HUMAN:243:541_7w1m_H_1 7w1m 243-541 View model · PDB
Predicted = Low TFS_sp_Q494X3_ZN404_HUMAN:269:545_5wjq_D_1 5wjq 269-545 View model · PDB
Predicted = Low TFS_sp_Q494X3_ZN404_HUMAN:392:545_2i13_A_1 2i13 392-545 View model · PDB
Predicted = Low TFS_sp_Q494X3_ZN404_HUMAN:409:518_5ei9_E_1 5ei9 409-518 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 5wjq 158:548 269 545 P:D · DNA:A,B 53.8% / 69.7% 98 View · PDB TFS_sp_Q494X3_ZN404_HUMAN:269:545_5wjq_D_1
2 5v3m 158:548 242 518 P:C · DNA:A,B 52.7% / 69.0% 100 View · PDB TFS_sp_Q494X3_ZN404_HUMAN:242:518_5v3m_C_1
3 5v3j 158:548 242 518 P:E · DNA:A,B 52.7% / 69.0% 100 View · PDB TFS_sp_Q494X3_ZN404_HUMAN:242:518_5v3j_E_1
4 2i13 158:548 392 545 P:A · DNA:C,D 52.6% / 64.3% 100 View · PDB TFS_sp_Q494X3_ZN404_HUMAN:392:545_2i13_A_1
1 1llm 158:548 493,493 546,546 P:C,D · DNA:A,B 40.7% / 59.3% 62,63 View · PDB DIMER_sp_Q494X3_ZN404_HUMAN:493:546_1llm_C_1
5 7w1m 158:548 243 541 P:H · DNA:F,G 35.1% / 49.4% 92 View · PDB TFS_sp_Q494X3_ZN404_HUMAN:243:541_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
5-46PF01352KRAB boxNo overlap with loaded model regions
159-181PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
187-209PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
215-237PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
271-293PF00096Zinc finger, C2H2 typeoverlaps 242-546
299-321PF00096Zinc finger, C2H2 typeoverlaps 242-546
327-351PF13912C2H2-type zinc fingeroverlaps 242-546
355-377PF00096Zinc finger, C2H2 typeoverlaps 242-546
383-405PF00096Zinc finger, C2H2 typeoverlaps 242-546
411-433PF00096Zinc finger, C2H2 typeoverlaps 242-546
439-461PF00096Zinc finger, C2H2 typeoverlaps 242-546
467-489PF00096Zinc finger, C2H2 typeoverlaps 242-546
495-517PF00096Zinc finger, C2H2 typeoverlaps 242-546
524-545PF00096Zinc finger, C2H2 typeoverlaps 242-546