ModCRE DB

Transcription factor

Q59EH4

Zinc finger protein 426

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 541 aa

35 Generated PWM 6 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)30
MotifPredictionSourceDNA bindingSupportLogoActions
M00939_2.00 NN 70-40% CisBP CCACCTCA 63.8% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 63.0% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 63.0% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 62.3% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 62.3% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 62.3% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 61.1% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 60.7% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 60.7% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 60.7% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 59.5% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 59.0% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 57.2% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 57.0% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 57.0% identity Open · Scan
M08985_2.00 NN 70-40% CisBP TGAGGACCTACTGTGTGCC 56.9% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 56.8% identity Open · Scan
M04613_2.00 NN 70-40% CisBP CTCATGTGCTAATTACAAA 53.6% identity Open · Scan
MA1602.1 NN 70-40% JASPAR CGTCTACACGGG 53.2% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 52.8% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 52.5% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 52.2% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 51.5% identity Open · Scan
M04465_2.00 NN 70-40% CisBP GTGATTCTTATCTTATCCTT 51.4% identity Open · Scan
M08901_2.00 NN 70-40% CisBP CCAGTTCACACC 51.4% identity Open · Scan
M08908_2.00 NN 70-40% CisBP GCTGCTGCTTCTGCTG 51.2% identity Open · Scan
M01474_2.00 NN 70-40% CisBP CGCCGATCAC 50.9% identity Open · Scan
M06179_2.00 NN 70-40% CisBP TAAGCCTATAGA 50.9% identity Open · Scan
M07707_2.00 NN 70-40% CisBP TCCCGC 50.9% identity Open · Scan
M01538_2.00 NN 70-40% CisBP GCCCCTGA 50.0% identity Open · Scan
ModCRE5
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_Q59EH4_Q59EH4_HUMAN:349:397_1llm_D_1 ModCRE Homology model TCGGCGCGCCGG Region 349-397 · 1 3D model Open · Scan
TFS_tr_Q59EH4_Q59EH4_HUMAN:263:541_5wjq_D_1 ModCRE Homology model CCCTGGGGGGGGGGCGGGGGGAATCTCT Region 263-541 · 1 3D model Open · Scan
TFS_tr_Q59EH4_Q59EH4_HUMAN:266:541_5v3j_E_1 ModCRE Homology model CCCCCCGGGGGGGAGGGGTCCCACAC Region 266-541 · 1 3D model Open · Scan
TFS_tr_Q59EH4_Q59EH4_HUMAN:266:541_5v3m_C_1 ModCRE Homology model CCCCCGGGGGGTGGCCGGCAAATCCA Region 266-541 · 1 3D model Open · Scan
TFS_tr_Q59EH4_Q59EH4_HUMAN:360:513_2i13_A_1 ModCRE Homology model CTTTTAAGAGTGCTATAGAAA Region 360-513 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 541 aa
263-541

Region 263-541 5 PWM

Residues
279 aa
Domains
PF13465 · Zinc-finger double domain PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
6 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
6 active PDB models 6 summary rows
Region 263-5416 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_Q59EH4_Q59EH4_HUMAN:349:397_1llm_D_1 1llm 349-397 View model · PDB
Predicted = Low TFS_tr_Q59EH4_Q59EH4_HUMAN:263:541_5wjq_D_1 5wjq 263-541 View model · PDB
Predicted = Low TFS_tr_Q59EH4_Q59EH4_HUMAN:264:537_7w1m_H_1 7w1m 264-537 View model · PDB
Predicted = Low TFS_tr_Q59EH4_Q59EH4_HUMAN:266:541_5v3j_E_1 5v3j 266-541 View model · PDB
Predicted = Low TFS_tr_Q59EH4_Q59EH4_HUMAN:266:541_5v3m_C_1 5v3m 266-541 View model · PDB
Predicted = Low TFS_tr_Q59EH4_Q59EH4_HUMAN:360:513_2i13_A_1 2i13 360-513 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 5wjq 263:541 263 541 P:D · DNA:A,B 53.0% / 66.7% 99 View · PDB TFS_tr_Q59EH4_Q59EH4_HUMAN:263:541_5wjq_D_1
1 1llm 263:541 349,349 397,397 P:C,D · DNA:A,B 51.0% / 63.3% 56,57 View · PDB DIMER_tr_Q59EH4_Q59EH4_HUMAN:349:397_1llm_D_1
4 2i13 263:541 360 513 P:A · DNA:C,D 50.6% / 66.9% 100 View · PDB TFS_tr_Q59EH4_Q59EH4_HUMAN:360:513_2i13_A_1
2 5v3m 263:541 266 541 P:C · DNA:A,B 48.2% / 67.0% 99 View · PDB TFS_tr_Q59EH4_Q59EH4_HUMAN:266:541_5v3m_C_1
3 5v3j 263:541 266 541 P:E · DNA:A,B 48.2% / 67.0% 99 View · PDB TFS_tr_Q59EH4_Q59EH4_HUMAN:266:541_5v3j_E_1
5 7w1m 263:541 264 537 P:H · DNA:F,G 35.3% / 51.6% 85 View · PDB TFS_tr_Q59EH4_Q59EH4_HUMAN:264:537_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
28-69PF01352KRAB boxNo overlap with loaded model regions
211-233PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
282-306PF13465Zinc-finger double domainoverlaps 263-541
323-345PF00096Zinc finger, C2H2 typeoverlaps 263-541
351-373PF00096Zinc finger, C2H2 typeoverlaps 263-541
379-401PF00096Zinc finger, C2H2 typeoverlaps 263-541
408-429PF00096Zinc finger, C2H2 typeoverlaps 263-541
435-457PF00096Zinc finger, C2H2 typeoverlaps 263-541
463-485PF00096Zinc finger, C2H2 typeoverlaps 263-541
491-513PF00096Zinc finger, C2H2 typeoverlaps 263-541
519-541PF00096Zinc finger, C2H2 typeoverlaps 263-541