Transcription factor

Q5MCW4 - ZNF569

Zinc finger protein 569

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 686 aa

77 Generated PWM 11 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)68

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	67.8% identity		Open · Scan
MA1124.1	NN 70-40%	JASPAR	CATTCATTCATTC	66.9% identity		Open · Scan
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	66.6% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	66.3% identity		Open · Scan
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	65.8% identity		Open · Scan
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	65.8% identity		Open · Scan
M00955_2.00	NN 70-40%	CisBP	ACGTCCTCT	65.4% identity		Open · Scan
M08395_2.00	NN 70-40%	CisBP	GCTGCCTACTCTTCC	64.3% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	63.7% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	63.5% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	62.5% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	62.3% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	62.3% identity		Open · Scan
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	62.3% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	61.3% identity		Open · Scan
M08985_2.00	NN 70-40%	CisBP	TGAGGACCTACTGTGTGCC	60.8% identity		Open · Scan
M08254_2.00	NN 70-40%	CisBP	CTGCCCTGGGACTTT	60.5% identity		Open · Scan
M04611_2.00	NN 70-40%	CisBP	CTTTCGGACAC	60.3% identity		Open · Scan
M04650_2.00	NN 70-40%	CisBP	GCATAACTGCCCCGCTGCC	60.1% identity		Open · Scan
M00782_2.00	NN 70-40%	CisBP	AGTGTGCGCTA	59.4% identity		Open · Scan
M08325_2.00	NN 70-40%	CisBP	TTTTTTTTT	59.4% identity		Open · Scan
M08267_2.00	NN 70-40%	CisBP	CAGTTTCATTTTCC	59.1% identity		Open · Scan
M08355_2.00	NN 70-40%	CisBP	GCGAACTCCTATTCATCC	58.8% identity		Open · Scan
M04610_2.00	NN 70-40%	CisBP	CGGCGACGCGAACAC	58.6% identity		Open · Scan
M08887_2.00	NN 70-40%	CisBP	CCTCCTCCAGGAAGCCTTCCCTGA	58.5% identity		Open · Scan
M00945_2.00	NN 70-40%	CisBP	CACCGCAC	58.1% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	58.1% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	57.7% identity		Open · Scan
M07610_2.00	NN 70-40%	CisBP	CCTTCTTCCTCCCCCCTGCCCACC	57.5% identity		Open · Scan
M07753_2.00	NN 70-40%	CisBP	TGCATTCCTTGGCTTGTG	57.5% identity		Open · Scan
M04621_2.00	NN 70-40%	CisBP	AGCAATTCCGCTCA	57.0% identity		Open · Scan
M04387_2.00	NN 70-40%	CisBP	CGTGCTCCCC	56.7% identity		Open · Scan
M07581_2.00	NN 70-40%	CisBP	TCCCCTGTGCTTCTCTCCCCT	56.3% identity		Open · Scan
M00786_2.00	NN 70-40%	CisBP	TATATATAT	56.2% identity		Open · Scan
M04465_2.00	NN 70-40%	CisBP	GTGATTCTTATCTTATCCTT	55.3% identity		Open · Scan
M08859_2.00	NN 70-40%	CisBP	CATTTTTTCCTCCTAGGCCT	55.3% identity		Open · Scan
M07587_2.00	NN 70-40%	CisBP	CCCCCTCCCCAGTCGAGCCCCCGC	55.2% identity		Open · Scan
M08901_2.00	NN 70-40%	CisBP	CCAGTTCACACC	55.0% identity		Open · Scan
M07648_2.00	NN 70-40%	CisBP	GCTTGCAAAAAAAATTTAACTCCCAGCTC	54.8% identity		Open · Scan
M04613_2.00	NN 70-40%	CisBP	CTCATGTGCTAATTACAAA	54.6% identity		Open · Scan
M06108_2.00	NN 70-40%	CisBP	ACAACAACAAC	54.5% identity		Open · Scan
M01456_2.00	NN 70-40%	CisBP	GTGATCGGCG	54.3% identity		Open · Scan
M07747_2.00	NN 70-40%	CisBP	TGGTCTATAAAGGGCCTGGTT	54.0% identity		Open · Scan
MA1602.1	NN 70-40%	JASPAR	CGTCTACACGGG	54.0% identity		Open · Scan
M04598_2.00	NN 70-40%	CisBP	CGCTAACTCTCCACA	53.4% identity		Open · Scan
M04536_2.00	NN 70-40%	CisBP	ACGTAACCCGATACC	53.3% identity		Open · Scan
M07683_2.00	NN 70-40%	CisBP	GTGGGAAAGCCT	53.1% identity		Open · Scan
M08366_2.00	NN 70-40%	CisBP	GTTTGCTGCTTACAA	53.1% identity		Open · Scan
M08373_2.00	NN 70-40%	CisBP	CCCCCTGGCTCTTCCTCT	53.1% identity		Open · Scan
MA1601.1	NN 70-40%	JASPAR	ATGTGGGAAA	53.1% identity		Open · Scan
M07627_2.00	NN 70-40%	CisBP	CAGTCACCTTCTGG	52.6% identity		Open · Scan
MA1154.1	NN 70-40%	JASPAR	CTTTCCCACAACACGAC	52.6% identity		Open · Scan
M03671_2.00	NN 70-40%	CisBP	ATTACCATACAAGTGCAC	52.5% identity		Open · Scan
M00609_2.00	NN 70-40%	CisBP	GGAAGCCCTA	52.2% identity		Open · Scan
M08390_2.00	NN 70-40%	CisBP	GCTTTGTTGACTCAC	52.2% identity		Open · Scan
M01474_2.00	NN 70-40%	CisBP	CGCCGATCAC	51.9% identity		Open · Scan
MA0528.1	NN 70-40%	JASPAR	GGAGGAGGAGGGGGAGGAGGA	51.9% identity		Open · Scan
M08283_2.00	NN 70-40%	CisBP	GACTTTTATTTT	51.8% identity		Open · Scan
MA1588.1	NN 70-40%	JASPAR	GAATTCTTGGTTGAC	51.8% identity		Open · Scan
M07578_2.00	NN 70-40%	CisBP	CAACTCTCC	51.7% identity		Open · Scan
M07702_2.00	NN 70-40%	CisBP	CTTCTTCCTTGG	51.5% identity		Open · Scan
M08367_2.00	NN 70-40%	CisBP	GGGGTGATGACCACTCTGGCTTCTTAC	51.4% identity		Open · Scan
M00641_2.00	NN 70-40%	CisBP	ATTGACCACT	51.2% identity		Open · Scan
MA1656.1	NN 70-40%	JASPAR	CCAAGCCCAACCAG	51.2% identity		Open · Scan
MA1587.1	NN 70-40%	JASPAR	CCTCGACCTCCTGA	50.8% identity		Open · Scan
M00217_2.00	NN 70-40%	CisBP	TTACTCAATAT	50.7% identity		Open · Scan
M07656_2.00	NN 70-40%	CisBP	TGTCTAGTAAGTCTA	50.1% identity		Open · Scan
M07689_2.00	NN 70-40%	CisBP	ACCCAGGCTCCTTCCATCTTGTGGCTC	50.1% identity		Open · Scan

ModCRE9

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
TFS_sp_Q5MCW4_ZN569_HUMAN:251:404_2i13_A_1	ModCRE	Homology model	AAGTAACTCCTGCAGCTGCGC	Region 251-404 · 1 3D model		Open · Scan
TFS_sp_Q5MCW4_ZN569_HUMAN:297:573_5v3j_E_1	ModCRE	Homology model	CCCCGGGGAGGAGCCCCAGGGGGGGG	Region 297-573 · 1 3D model		Open · Scan
TFS_sp_Q5MCW4_ZN569_HUMAN:297:573_5v3m_C_1	ModCRE	Homology model	GGGGAGTGGGGGGCGGGAGGGGGTTC	Region 297-573 · 1 3D model		Open · Scan
TFS_sp_Q5MCW4_ZN569_HUMAN:323:601_5wjq_D_1	ModCRE	Homology model	GGGGGGCCCGGGGGGCGGGGGGCGGAAC	Region 323-601 · 1 3D model		Open · Scan
TFS_sp_Q5MCW4_ZN569_HUMAN:603:684_1g2f_C_1	ModCRE	Homology model	TGGGGGGGGTGCACC	Region 603-684 · 1 3D model		Open · Scan
TFS_sp_Q5MCW4_ZN569_HUMAN:603:684_4r2a_A_1	ModCRE	Homology model	GGCGGGGGCG	Region 603-684 · 1 3D model		Open · Scan
TFS_sp_Q5MCW4_ZN569_HUMAN:603:684_4r2c_A_1	ModCRE	Homology model	GGACGGGGCA	Region 603-684 · 1 3D model		Open · Scan
TFS_sp_Q5MCW4_ZN569_HUMAN:603:684_4x9j_A_1	ModCRE	Homology model	GGGGAGGGCA	Region 603-684 · 1 3D model		Open · Scan
TFS_sp_Q5MCW4_ZN569_HUMAN:604:684_1a1h_A_1	ModCRE	Homology model	GGGGGGGTCA	Region 604-684 · 1 3D model		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 686 aa

251-601

603-684

Region 251-601 4 PWM

Residues

351 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

5 active PDBs · 5 summary rows

Templates

2I13, 5V3J, 5V3M, 5WJQ, 7W1M

Sources

Predicted = Low

Scan this region Show models

Region 603-684 5 PWM

Residues

82 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

6 active PDBs · 1 summary row

Templates

1A1H, 1G2F, 1LLM, 4R2A, 4R2C, 4X9J

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

11 active PDB models 6 summary rows

Region 251-6015 models · 5 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	TFS_sp_Q5MCW4_ZN569_HUMAN:251:404_2i13_A_1	2i13	251-404	View model · PDB
Predicted = Low	TFS_sp_Q5MCW4_ZN569_HUMAN:297:573_5v3j_E_1	5v3j	297-573	View model · PDB
Predicted = Low	TFS_sp_Q5MCW4_ZN569_HUMAN:297:573_5v3m_C_1	5v3m	297-573	View model · PDB
Predicted = Low	TFS_sp_Q5MCW4_ZN569_HUMAN:298:596_7w1m_H_1	7w1m	298-596	View model · PDB
Predicted = Low	TFS_sp_Q5MCW4_ZN569_HUMAN:323:601_5wjq_D_1	5wjq	323-601	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
4	2i13	219:685	251	404	P:A · DNA:C,D	60.4% / 74.0%	100	View · PDB TFS_sp_Q5MCW4_ZN569_HUMAN:251:404_2i13_A_1
2	5v3m	219:685	297	573	P:C · DNA:A,B	55.2% / 70.4%	100	View · PDB TFS_sp_Q5MCW4_ZN569_HUMAN:297:573_5v3m_C_1
3	5v3j	219:685	297	573	P:E · DNA:A,B	55.2% / 70.4%	100	View · PDB TFS_sp_Q5MCW4_ZN569_HUMAN:297:573_5v3j_E_1
1	5wjq	219:685	323	601	P:D · DNA:A,B	55.2% / 70.3%	99	View · PDB TFS_sp_Q5MCW4_ZN569_HUMAN:323:601_5wjq_D_1
5	7w1m	219:685	298	596	P:H · DNA:F,G	36.0% / 52.9%	92	View · PDB TFS_sp_Q5MCW4_ZN569_HUMAN:298:596_7w1m_H_1

Region 603-6846 models · 1 summary row

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_sp_Q5MCW4_ZN569_HUMAN:604:652_1llm_D_1	1llm	604-652	View model · PDB
Predicted = Low	TFS_sp_Q5MCW4_ZN569_HUMAN:603:684_1g2f_C_1	1g2f	603-684	View model · PDB
Predicted = Low	TFS_sp_Q5MCW4_ZN569_HUMAN:603:684_4r2a_A_1	4r2a	603-684	View model · PDB
Predicted = Low	TFS_sp_Q5MCW4_ZN569_HUMAN:603:684_4r2c_A_1	4r2c	603-684	View model · PDB
Predicted = Low	TFS_sp_Q5MCW4_ZN569_HUMAN:603:684_4x9j_A_1	4x9j	603-684	View model · PDB
Predicted = Low	TFS_sp_Q5MCW4_ZN569_HUMAN:604:684_1a1h_A_1	1a1h	604-684	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
1	1llm	219:685	604,604	652,652	P:C,D · DNA:A,B	49.0% / 63.3%	56,57	View · PDB DIMER_sp_Q5MCW4_ZN569_HUMAN:604:652_1llm_D_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
8-48	PF01352	KRAB box	No overlap with loaded model regions
186-208	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
214-236	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
242-264	PF00096	Zinc finger, C2H2 type	overlaps 251-601
270-292	PF00096	Zinc finger, C2H2 type	overlaps 251-601
298-320	PF00096	Zinc finger, C2H2 type	overlaps 251-601
326-348	PF00096	Zinc finger, C2H2 type	overlaps 251-601
354-376	PF00096	Zinc finger, C2H2 type	overlaps 251-601
382-404	PF00096	Zinc finger, C2H2 type	overlaps 251-601
410-432	PF00096	Zinc finger, C2H2 type	overlaps 251-601
438-460	PF00096	Zinc finger, C2H2 type	overlaps 251-601
466-488	PF00096	Zinc finger, C2H2 type	overlaps 251-601
494-516	PF00096	Zinc finger, C2H2 type	overlaps 251-601
522-544	PF00096	Zinc finger, C2H2 type	overlaps 251-601
550-572	PF00096	Zinc finger, C2H2 type	overlaps 251-601
578-600	PF00096	Zinc finger, C2H2 type	overlaps 251-601
606-628	PF00096	Zinc finger, C2H2 type	overlaps 603-684
634-656	PF00096	Zinc finger, C2H2 type	overlaps 603-684
662-684	PF00096	Zinc finger, C2H2 type	overlaps 603-684