ModCRE DB

Transcription factor

Q5VVR8 - TCF7L2

Transcription factor 7 like 2

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 282 aa

10 Generated PWM 1 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)6
MotifPredictionSourceDNA bindingSupportLogoActions
M00198_2.00 NN 70+% CisBP AGATCAAAGG 99.2% identity Open · Scan
M08167_2.00 NN 70+% CisBP AAAGATCAAAGGAA 94.2% identity Open · Scan
MA0523.1 NN 70+% JASPAR AAAGATCAAAGGAA 94.2% identity Open · Scan
MA1421.1 NN 70+% JASPAR AAAGATCAAAGG 75.8% identity Open · Scan
MA0522.1 NN 70+% JASPAR CACAGCTGCAG 74.6% identity Open · Scan
MA0768.1 NN 70+% JASPAR AAAGATCAAAGGGTT 73.8% identity Open · Scan
Nearest Neighbor (70% - 40%)4
MotifPredictionSourceDNA bindingSupportLogoActions
M09392_2.00 NN 70-40% CisBP TCCTTTGATTTGCT 65.4% identity Open · Scan
MA0769.1 NN 70-40% JASPAR AAAGATCAAAGG 56.9% identity Open · Scan
M05755_2.00 NN 70-40% CisBP ACATCAAAG 56.8% identity Open · Scan
MA0769.2 NN 70-40% JASPAR TCCTTTGATGT 54.0% identity Open · Scan
ModCRE0

No generated PWM in this category.

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 282 aa
165-234

Region 165-234 0 PWM

Residues
70 aa
Domains
PF00505 · HMG (high mobility group) box
3D models
1 active PDB
Templates
4S2Q
Sources
Structure model
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
1 active PDB model
Region 165-2341 model
Actions
Predicted = Low TFS_Q5VVR8:165:234_4s2q_D_1 4s2q 165-234 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
2-76PF08347N-terminal CTNNB1 bindingNo overlap with loaded model regions
167-235PF00505HMG (high mobility group) boxoverlaps 165-234
262-280PF27556Zinc finger protein 704 C-terminal domainNo overlap with loaded model regions