ModCRE DB

Transcription factor

Q68DE3 - USF3

Basic helix-loop-helix domain-containing protein USF3 (Upstream transcription factor 3)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 2245 aa

11 Generated PWM 18 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)1
MotifPredictionSourceDNA bindingSupportLogoActions
M05982_2.00 NN 70-40% CisBP ACCACGTGAC 51.7% identity Open · Scan
ModCRE10
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q68DE3_USF3_HUMAN:17:72_4ati_B_1 ModCRE Homology model GGTCCCCCATGGGGCC Region 17-72 · 1 3D model Open · Scan
DIMER_sp_Q68DE3_USF3_HUMAN:17:72_7d8t_B_1 ModCRE Homology model GGGCCCACGTGTGGC Region 17-72 · 1 3D model Open · Scan
DIMER_sp_Q68DE3_USF3_HUMAN:20:103_8ia3_A_1 ModCRE Homology model GGCCACACGCGGTATAAA Region 20-103 · 1 3D model Open · Scan
DIMER_sp_Q68DE3_USF3_HUMAN:20:103_8ia3_B_1 ModCRE Homology model GGGCGCACGTGTGTAGAA Region 20-103 · 1 3D model Open · Scan
DIMER_sp_Q68DE3_USF3_HUMAN:20:103_8ia3_E_1 ModCRE Homology model TGGTCCACGCGTGCGACA Region 20-103 · 1 3D model Open · Scan
DIMER_sp_Q68DE3_USF3_HUMAN:20:73_1hlo_A_1 ModCRE Homology model TCCCCCGGGGG Region 20-73 · 1 3D model Open · Scan
DIMER_sp_Q68DE3_USF3_HUMAN:20:73_1nkp_B_1 ModCRE Homology model GGGTCTCACGGGGCACCA Region 20-73 · 1 3D model Open · Scan
TFS_sp_Q68DE3_USF3_HUMAN:17:73_1an4_A_1 ModCRE Homology model TGGCCCCCCCGGGGCCCCCA Region 17-73 · 1 3D model Open · Scan
TFS_sp_Q68DE3_USF3_HUMAN:17:73_1an4_B_1 ModCRE Homology model GGGGGCACCGTGGGCTCACG Region 17-73 · 1 3D model Open · Scan
TFS_sp_Q68DE3_USF3_HUMAN:20:72_4atk_B_1 ModCRE Homology model GTACCCCCGGTGGGGG Region 20-72 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 2245 aa
14-103

Region 14-103 10 PWM

Residues
90 aa
Domains
PF00010 · Helix-loop-helix DNA-binding domain
3D models
18 active PDBs · 10 summary rows
Templates
1AM9, 1AN4, 1HLO, 1NKP, 4ATI, 4ATK, 5I50, 7D8T, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
18 active PDB models 10 summary rows
Region 14-10318 models · 10 summary rows
Actions
Predicted = Low DIMER_sp_Q68DE3_USF3_HUMAN:14:76_1am9_A_1 1am9 14-76 View model · PDB
Predicted = Low DIMER_sp_Q68DE3_USF3_HUMAN:14:76_1am9_C_1 1am9 14-76 View model · PDB
Predicted = Low DIMER_sp_Q68DE3_USF3_HUMAN:17:72_4ati_B_1 4ati 17-72 View model · PDB
Predicted = Low DIMER_sp_Q68DE3_USF3_HUMAN:17:72_7d8t_B_1 7d8t 17-72 View model · PDB
Predicted = Low DIMER_sp_Q68DE3_USF3_HUMAN:20:103_8ia3_A_1 8ia3 20-103 View model · PDB
Predicted = Low DIMER_sp_Q68DE3_USF3_HUMAN:20:103_8ia3_B_1 8ia3 20-103 View model · PDB
Predicted = Low DIMER_sp_Q68DE3_USF3_HUMAN:20:103_8ia3_E_1 8ia3 20-103 View model · PDB
Predicted = Low DIMER_sp_Q68DE3_USF3_HUMAN:20:73_1hlo_A_1 1hlo 20-73 View model · PDB
Predicted = Low DIMER_sp_Q68DE3_USF3_HUMAN:20:73_1nkp_B_1 1nkp 20-73 View model · PDB
Predicted = Low DIMER_sp_Q68DE3_USF3_HUMAN:20:77_5i50_B_1 5i50 20-77 View model · PDB
Predicted = Low TFS_sp_Q68DE3_USF3_HUMAN:17:72_4ati_B_1 4ati 17-72 View model · PDB
Predicted = Low TFS_sp_Q68DE3_USF3_HUMAN:17:72_7d8t_B_1 7d8t 17-72 View model · PDB
Predicted = Low TFS_sp_Q68DE3_USF3_HUMAN:17:73_1an4_A_1 1an4 17-73 View model · PDB
Predicted = Low TFS_sp_Q68DE3_USF3_HUMAN:17:73_1an4_B_1 1an4 17-73 View model · PDB
Predicted = Low TFS_sp_Q68DE3_USF3_HUMAN:20:103_8ia3_A_1 8ia3 20-103 View model · PDB
Predicted = Low TFS_sp_Q68DE3_USF3_HUMAN:20:103_8ia3_B_1 8ia3 20-103 View model · PDB
Predicted = Low TFS_sp_Q68DE3_USF3_HUMAN:20:103_8ia3_E_1 8ia3 20-103 View model · PDB
Predicted = Low TFS_sp_Q68DE3_USF3_HUMAN:20:72_4atk_B_1 4atk 20-72 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 7d8t 14:103 17,17 72,72 P:A,B · DNA:C,D 36.2% / 60.3% 28,28 View · PDB DIMER_sp_Q68DE3_USF3_HUMAN:17:72_7d8t_B_1
1 7d8t 14:103 17,17 72,72 P:A,B · DNA:C,D 36.2% / 60.3% 28,28 View · PDB TFS_sp_Q68DE3_USF3_HUMAN:17:72_7d8t_B_1
5 4ati 14:103 23,17 72,72 P:A,B · DNA:C,D 36.2% / 60.3% 84,78 View · PDB DIMER_sp_Q68DE3_USF3_HUMAN:17:72_4ati_B_1
5 4ati 14:103 23,17 72,72 P:A,B · DNA:C,D 36.2% / 60.3% 84,78 View · PDB TFS_sp_Q68DE3_USF3_HUMAN:17:72_4ati_B_1
2 8ia3 14:103 20,20 103,103 P:A,F · DNA:G,H 36.0% / 57.3% 77,80 View · PDB DIMER_sp_Q68DE3_USF3_HUMAN:20:103_8ia3_A_1
2 8ia3 14:103 20,20 103,103 P:A,F · DNA:G,H 36.0% / 57.3% 77,80 View · PDB TFS_sp_Q68DE3_USF3_HUMAN:20:103_8ia3_A_1
3 8ia3 14:103 20,20 103,103 P:E,F · DNA:G,H 36.0% / 57.3% 75,80 View · PDB DIMER_sp_Q68DE3_USF3_HUMAN:20:103_8ia3_E_1
3 8ia3 14:103 20,20 103,103 P:E,F · DNA:G,H 36.0% / 57.3% 75,80 View · PDB TFS_sp_Q68DE3_USF3_HUMAN:20:103_8ia3_E_1
4 8ia3 14:103 20,20 103,103 P:B,F · DNA:G,H 36.0% / 57.3% 84,80 View · PDB DIMER_sp_Q68DE3_USF3_HUMAN:20:103_8ia3_B_1
4 8ia3 14:103 20,20 103,103 P:B,F · DNA:G,H 36.0% / 57.3% 84,80 View · PDB TFS_sp_Q68DE3_USF3_HUMAN:20:103_8ia3_B_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
20-70PF00010Helix-loop-helix DNA-binding domainoverlaps 14-103