ModCRE DB

Transcription factor

Q68EA5 - ZNF57

Zinc finger protein 57 (Zinc finger protein 424)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 555 aa

26 Generated PWM 8 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)24
MotifPredictionSourceDNA bindingSupportLogoActions
M00939_2.00 NN 70-40% CisBP CCACCTCA 63.5% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 58.8% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 58.3% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 57.6% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 57.6% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 57.6% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 57.1% identity Open · Scan
M07733_2.00 NN 70-40% CisBP TCTTTCTCTCTCTCC 56.5% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 56.4% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 55.9% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 55.2% identity Open · Scan
M08254_2.00 NN 70-40% CisBP CTGCCCTGGGACTTT 53.8% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 53.5% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 53.1% identity Open · Scan
M07620_2.00 NN 70-40% CisBP TTGGATCTGTGGATTCATGTCTTTCAT 51.9% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 51.1% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 50.8% identity Open · Scan
M07753_2.00 NN 70-40% CisBP TGCATTCCTTGGCTTGTG 50.4% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 50.3% identity Open · Scan
MA1602.1 NN 70-40% JASPAR CGTCTACACGGG 50.2% identity Open · Scan
M01474_2.00 NN 70-40% CisBP CGCCGATCAC 50.0% identity Open · Scan
M01540_2.00 NN 70-40% CisBP CTCCCCC 50.0% identity Open · Scan
M07562_2.00 NN 70-40% CisBP GAAAAAAAC 50.0% identity Open · Scan
M08908_2.00 NN 70-40% CisBP GCTGCTGCTTCTGCTG 50.0% identity Open · Scan
ModCRE2
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_sp_Q68EA5_ZNF57_HUMAN:249:359_5egb_A_1 ModCRE Homology model CGGTGAGGGGGGGGCCGG Region 249-359 · 1 3D model Open · Scan
TFS_sp_Q68EA5_ZNF57_HUMAN:249:359_5ei9_E_1 ModCRE Homology model GGGGGGGGGGGGGGCCC Region 249-359 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 555 aa
171-527

Region 171-527 2 PWM

Residues
357 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
8 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5EGB, 5EI9, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
8 active PDB models 6 summary rows
Region 171-5278 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_Q68EA5_ZNF57_HUMAN:306:354_1llm_D_1 1llm 306-354 View model · PDB
Predicted = Low TFS_sp_Q68EA5_ZNF57_HUMAN:171:466_7w1m_H_1 7w1m 171-466 View model · PDB
Predicted = Low TFS_sp_Q68EA5_ZNF57_HUMAN:224:499_5v3j_E_1 5v3j 224-499 View model · PDB
Predicted = Low TFS_sp_Q68EA5_ZNF57_HUMAN:224:499_5v3m_C_1 5v3m 224-499 View model · PDB
Predicted = Low TFS_sp_Q68EA5_ZNF57_HUMAN:242:386_2i13_A_1 2i13 242-386 View model · PDB
Predicted = Low TFS_sp_Q68EA5_ZNF57_HUMAN:249:359_5egb_A_1 5egb 249-359 View model · PDB
Predicted = Low TFS_sp_Q68EA5_ZNF57_HUMAN:249:359_5ei9_E_1 5ei9 249-359 View model · PDB
Predicted = Low TFS_sp_Q68EA5_ZNF57_HUMAN:249:527_5wjq_D_1 5wjq 249-527 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
5 2i13 171:527 242 386 P:A · DNA:C,D 52.4% / 64.8% 94 View · PDB TFS_sp_Q68EA5_ZNF57_HUMAN:242:386_2i13_A_1
1 5wjq 171:527 249 527 P:D · DNA:A,B 45.9% / 63.4% 99 View · PDB TFS_sp_Q68EA5_ZNF57_HUMAN:249:527_5wjq_D_1
2 5v3m 171:527 224 499 P:C · DNA:A,B 43.8% / 62.7% 99 View · PDB TFS_sp_Q68EA5_ZNF57_HUMAN:224:499_5v3m_C_1
3 5v3j 171:527 224 499 P:E · DNA:A,B 43.8% / 62.7% 99 View · PDB TFS_sp_Q68EA5_ZNF57_HUMAN:224:499_5v3j_E_1
1 1llm 171:527 306,306 354,354 P:C,D · DNA:A,B 40.8% / 63.3% 56,57 View · PDB DIMER_sp_Q68EA5_ZNF57_HUMAN:306:354_1llm_D_1
4 7w1m 171:527 171 466 P:H · DNA:F,G 34.8% / 48.9% 91 View · PDB TFS_sp_Q68EA5_ZNF57_HUMAN:171:466_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
3-44PF01352KRAB boxNo overlap with loaded model regions
140-162PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
252-274PF00096Zinc finger, C2H2 typeoverlaps 171-527
280-302PF00096Zinc finger, C2H2 typeoverlaps 171-527
308-330PF00096Zinc finger, C2H2 typeoverlaps 171-527
336-358PF00096Zinc finger, C2H2 typeoverlaps 171-527
364-386PF00096Zinc finger, C2H2 typeoverlaps 171-527
392-414PF00096Zinc finger, C2H2 typeoverlaps 171-527
420-442PF00096Zinc finger, C2H2 typeoverlaps 171-527
448-470PF00096Zinc finger, C2H2 typeoverlaps 171-527
476-498PF00096Zinc finger, C2H2 typeoverlaps 171-527