Transcription factor

Q6ECI4 - ZNF470

Zinc finger protein 470 (Chondrogenesis zinc finger protein 1) (CZF-1)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 717 aa

85 Generated PWM 11 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)76

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M00955_2.00	NN 70-40%	CisBP	ACGTCCTCT	68.2% identity		Open · Scan
M04653_2.00	NN 70-40%	CisBP	GGTACGGTTGTCCATGTTGCAA	68.2% identity		Open · Scan
MA1124.1	NN 70-40%	JASPAR	CATTCATTCATTC	66.0% identity		Open · Scan
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	65.8% identity		Open · Scan
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	65.8% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	64.7% identity		Open · Scan
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	64.7% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	64.7% identity		Open · Scan
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	64.7% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	64.7% identity		Open · Scan
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	64.7% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	64.7% identity		Open · Scan
M04650_2.00	NN 70-40%	CisBP	GCATAACTGCCCCGCTGCC	64.7% identity		Open · Scan
M04611_2.00	NN 70-40%	CisBP	CTTTCGGACAC	63.7% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	63.5% identity		Open · Scan
M07613_2.00	NN 70-40%	CisBP	TCACTCAGTCATTCA	62.6% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	61.0% identity		Open · Scan
M00782_2.00	NN 70-40%	CisBP	AGTGTGCGCTA	60.4% identity		Open · Scan
M07677_2.00	NN 70-40%	CisBP	CCCCGCCTCCCTTGCCGCTGC	60.0% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	60.0% identity		Open · Scan
M08355_2.00	NN 70-40%	CisBP	GCGAACTCCTATTCATCC	59.9% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	59.8% identity		Open · Scan
M08254_2.00	NN 70-40%	CisBP	CTGCCCTGGGACTTT	59.7% identity		Open · Scan
M04387_2.00	NN 70-40%	CisBP	CGTGCTCCCC	59.4% identity		Open · Scan
M08325_2.00	NN 70-40%	CisBP	TTTTTTTTT	58.7% identity		Open · Scan
M08887_2.00	NN 70-40%	CisBP	CCTCCTCCAGGAAGCCTTCCCTGA	58.6% identity		Open · Scan
M08395_2.00	NN 70-40%	CisBP	GCTGCCTACTCTTCC	57.4% identity		Open · Scan
M04465_2.00	NN 70-40%	CisBP	GTGATTCTTATCTTATCCTT	57.1% identity		Open · Scan
M04613_2.00	NN 70-40%	CisBP	CTCATGTGCTAATTACAAA	57.1% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	57.1% identity		Open · Scan
M07753_2.00	NN 70-40%	CisBP	TGCATTCCTTGGCTTGTG	56.9% identity		Open · Scan
M07581_2.00	NN 70-40%	CisBP	TCCCCTGTGCTTCTCTCCCCT	56.7% identity		Open · Scan
M07635_2.00	NN 70-40%	CisBP	AAGTTTTCTTGTATTATATCT	56.5% identity		Open · Scan
M08901_2.00	NN 70-40%	CisBP	CCAGTTCACACC	55.3% identity		Open · Scan
M00609_2.00	NN 70-40%	CisBP	GGAAGCCCTA	55.2% identity		Open · Scan
M08949_2.00	NN 70-40%	CisBP	TTCTATTTCTTCTTGTGTCA	54.9% identity		Open · Scan
M00786_2.00	NN 70-40%	CisBP	TATATATAT	54.6% identity		Open · Scan
M04536_2.00	NN 70-40%	CisBP	ACGTAACCCGATACC	54.5% identity		Open · Scan
M00945_2.00	NN 70-40%	CisBP	CACCGCAC	54.0% identity		Open · Scan
M04598_2.00	NN 70-40%	CisBP	CGCTAACTCTCCACA	53.9% identity		Open · Scan
M07693_2.00	NN 70-40%	CisBP	CTCCTGTGTGTGCCTTGGCTG	53.8% identity		Open · Scan
M07578_2.00	NN 70-40%	CisBP	CAACTCTCC	53.7% identity		Open · Scan
M07702_2.00	NN 70-40%	CisBP	CTTCTTCCTTGG	53.7% identity		Open · Scan
M08908_2.00	NN 70-40%	CisBP	GCTGCTGCTTCTGCTG	53.6% identity		Open · Scan
M04621_2.00	NN 70-40%	CisBP	AGCAATTCCGCTCA	53.4% identity		Open · Scan
M08373_2.00	NN 70-40%	CisBP	CCCCCTGGCTCTTCCTCT	53.1% identity		Open · Scan
M01044_2.00	NN 70-40%	CisBP	TCTCTCTTTC	52.7% identity		Open · Scan
M07659_2.00	NN 70-40%	CisBP	GTCTTCCAAGTAGCTGGTGTT	52.7% identity		Open · Scan
MA1154.1	NN 70-40%	JASPAR	CTTTCCCACAACACGAC	52.5% identity		Open · Scan
M00645_2.00	NN 70-40%	CisBP	CGCCCACGCA	52.3% identity		Open · Scan
M08283_2.00	NN 70-40%	CisBP	GACTTTTATTTT	52.3% identity		Open · Scan
M07731_2.00	NN 70-40%	CisBP	TTTCCCAGCAGCAACAGCACCGCCCCCCCC	52.2% identity		Open · Scan
M01456_2.00	NN 70-40%	CisBP	GTGATCGGCG	52.1% identity		Open · Scan
MA1587.1	NN 70-40%	JASPAR	CCTCGACCTCCTGA	52.1% identity		Open · Scan
M07587_2.00	NN 70-40%	CisBP	CCCCCTCCCCAGTCGAGCCCCCGC	52.0% identity		Open · Scan
M07678_2.00	NN 70-40%	CisBP	CCCGCCCCCTCCTCCCCCTTCCCACCC	51.9% identity		Open · Scan
M08314_2.00	NN 70-40%	CisBP	ATTCATCAAGGTCCTCAACAATGG	51.9% identity		Open · Scan
M07727_2.00	NN 70-40%	CisBP	CGCCGCCTCCCC	51.8% identity		Open · Scan
MA1602.1	NN 70-40%	JASPAR	CGTCTACACGGG	51.7% identity		Open · Scan
M07683_2.00	NN 70-40%	CisBP	GTGGGAAAGCCT	51.3% identity		Open · Scan
M08859_2.00	NN 70-40%	CisBP	CATTTTTTCCTCCTAGGCCT	51.3% identity		Open · Scan
MA1601.1	NN 70-40%	JASPAR	ATGTGGGAAA	51.3% identity		Open · Scan
M08392_2.00	NN 70-40%	CisBP	CTTCACCTGCTGAGG	51.2% identity		Open · Scan
M07634_2.00	NN 70-40%	CisBP	AAACGTCCACG	51.1% identity		Open · Scan
M01474_2.00	NN 70-40%	CisBP	CGCCGATCAC	50.9% identity		Open · Scan
M03671_2.00	NN 70-40%	CisBP	ATTACCATACAAGTGCAC	50.8% identity		Open · Scan
M00143_2.00	NN 70-40%	CisBP	CCCCCCCACG	50.6% identity		Open · Scan
MA0753.1	NN 70-40%	JASPAR	CCCCCCCCAC	50.6% identity		Open · Scan
M07628_2.00	NN 70-40%	CisBP	AGTGGTTCTGCTTCT	50.3% identity		Open · Scan
M08274_2.00	NN 70-40%	CisBP	TTACTTGCAGCCCAACGCATTCCTAAC	50.2% identity		Open · Scan
MA1656.1	NN 70-40%	JASPAR	CCAAGCCCAACCAG	50.2% identity		Open · Scan
M01531_2.00	NN 70-40%	CisBP	CCCCCCCTAAAT	50.0% identity		Open · Scan
M02731_2.00	NN 70-40%	CisBP	CACTTTCACTTT	50.0% identity		Open · Scan
M07700_2.00	NN 70-40%	CisBP	ATGTTGTGAGGAAGCCCA	50.0% identity		Open · Scan
MA0508.1	NN 70-40%	JASPAR	AGAAAGTGAAAGTGA	50.0% identity		Open · Scan
MA0750.1	NN 70-40%	JASPAR	GGCGACCACCGA	50.0% identity		Open · Scan

ModCRE9

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
TFS_sp_Q6ECI4_ZN470_HUMAN:392:421_1g2d_C_1	ModCRE	Homology model	CTTTTTCCAAGGC	Region 392-421 · 1 3D model		Open · Scan
TFS_sp_Q6ECI4_ZN470_HUMAN:392:421_2i13_A_1	ModCRE	Homology model	GTTAAACTAGGCAA	Region 392-421 · 1 3D model		Open · Scan
TFS_sp_Q6ECI4_ZN470_HUMAN:392:421_5egb_A_1	ModCRE	Homology model	TCCCCGAGGAGAA	Region 392-421 · 1 3D model		Open · Scan
TFS_sp_Q6ECI4_ZN470_HUMAN:392:421_5eh2_F_1	ModCRE	Homology model	CCCGGCAGGAAT	Region 392-421 · 1 3D model		Open · Scan
TFS_sp_Q6ECI4_ZN470_HUMAN:392:421_5ei9_E_1	ModCRE	Homology model	CCCCCGGCGGAGT	Region 392-421 · 1 3D model		Open · Scan
TFS_sp_Q6ECI4_ZN470_HUMAN:422:700_5wjq_D_1	ModCRE	Homology model	CGGCACAGGCCCGCCCGCGGCCCCCCCC	Region 422-700 · 1 3D model		Open · Scan
TFS_sp_Q6ECI4_ZN470_HUMAN:424:700_5v3j_E_1	ModCRE	Homology model	CCCCCGTCCCTGGGGGGGGGAGGGGG	Region 424-700 · 1 3D model		Open · Scan
TFS_sp_Q6ECI4_ZN470_HUMAN:424:700_5v3m_C_1	ModCRE	Homology model	GGACCCAGCCACCCGTGGCCCCCACC	Region 424-700 · 1 3D model		Open · Scan
TFS_sp_Q6ECI4_ZN470_HUMAN:462:615_2i13_A_1	ModCRE	Homology model	ACCCTAGGCCTTAGTCTTATC	Region 462-615 · 1 3D model		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 717 aa

312-700

Region 312-700 9 PWM

Residues

389 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

11 active PDBs · 6 summary rows

Templates

1G2D, 1LLM, 2I13, 5EGB, 5EH2, 5EI9, 5V3J, 5V3M, ...

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

11 active PDB models 6 summary rows

Region 312-70011 models · 6 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_sp_Q6ECI4_ZN470_HUMAN:451:502_1llm_D_1	1llm	451-502	View model · PDB
Predicted = Low	TFS_sp_Q6ECI4_ZN470_HUMAN:312:611_7w1m_H_1	7w1m	312-611	View model · PDB
Predicted = Low	TFS_sp_Q6ECI4_ZN470_HUMAN:392:421_1g2d_C_1	1g2d	392-421	View model · PDB
Predicted = Low	TFS_sp_Q6ECI4_ZN470_HUMAN:392:421_2i13_A_1	2i13	392-421	View model · PDB
Predicted = Low	TFS_sp_Q6ECI4_ZN470_HUMAN:392:421_5egb_A_1	5egb	392-421	View model · PDB
Predicted = Low	TFS_sp_Q6ECI4_ZN470_HUMAN:392:421_5eh2_F_1	5eh2	392-421	View model · PDB
Predicted = Low	TFS_sp_Q6ECI4_ZN470_HUMAN:392:421_5ei9_E_1	5ei9	392-421	View model · PDB
Predicted = Low	TFS_sp_Q6ECI4_ZN470_HUMAN:422:700_5wjq_D_1	5wjq	422-700	View model · PDB
Predicted = Low	TFS_sp_Q6ECI4_ZN470_HUMAN:424:700_5v3j_E_1	5v3j	424-700	View model · PDB
Predicted = Low	TFS_sp_Q6ECI4_ZN470_HUMAN:424:700_5v3m_C_1	5v3m	424-700	View model · PDB
Predicted = Low	TFS_sp_Q6ECI4_ZN470_HUMAN:462:615_2i13_A_1	2i13	462-615	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
5	2i13	255:700	462	615	P:A · DNA:C,D	60.4% / 71.4%	100	View · PDB TFS_sp_Q6ECI4_ZN470_HUMAN:462:615_2i13_A_1
1	5wjq	255:700	422	700	P:D · DNA:A,B	56.3% / 71.3%	99	View · PDB TFS_sp_Q6ECI4_ZN470_HUMAN:422:700_5wjq_D_1
2	5v3m	255:700	424	700	P:C · DNA:A,B	54.2% / 71.5%	100	View · PDB TFS_sp_Q6ECI4_ZN470_HUMAN:424:700_5v3m_C_1
3	5v3j	255:700	424	700	P:E · DNA:A,B	54.2% / 71.5%	100	View · PDB TFS_sp_Q6ECI4_ZN470_HUMAN:424:700_5v3j_E_1
1	1llm	255:700	451,451	502,502	P:C,D · DNA:A,B	46.2% / 59.6%	59,61	View · PDB DIMER_sp_Q6ECI4_ZN470_HUMAN:451:502_1llm_D_1
4	7w1m	255:700	312	611	P:H · DNA:F,G	37.7% / 53.9%	93	View · PDB TFS_sp_Q6ECI4_ZN470_HUMAN:312:611_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
22-63	PF01352	KRAB box	No overlap with loaded model regions
229-250	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
256-278	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
284-306	PF00096	Zinc finger, C2H2 type	No overlap with loaded model regions
312-334	PF00096	Zinc finger, C2H2 type	overlaps 312-700
340-362	PF00096	Zinc finger, C2H2 type	overlaps 312-700
368-391	PF00096	Zinc finger, C2H2 type	overlaps 312-700
425-447	PF00096	Zinc finger, C2H2 type	overlaps 312-700
453-475	PF00096	Zinc finger, C2H2 type	overlaps 312-700
481-503	PF00096	Zinc finger, C2H2 type	overlaps 312-700
509-531	PF00096	Zinc finger, C2H2 type	overlaps 312-700
537-559	PF00096	Zinc finger, C2H2 type	overlaps 312-700
565-587	PF00096	Zinc finger, C2H2 type	overlaps 312-700
621-643	PF00096	Zinc finger, C2H2 type	overlaps 312-700
649-671	PF00096	Zinc finger, C2H2 type	overlaps 312-700
677-699	PF00096	Zinc finger, C2H2 type	overlaps 312-700