ModCRE DB

Transcription factor

Q6NVX3 - TCF15

TCF15 protein

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 223 aa

30 Generated PWM 12 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)28
MotifPredictionSourceDNA bindingSupportLogoActions
M01718_2.00 NN 70-40% CisBP AACATATGGT 64.2% identity Open · Scan
MA0633.1 NN 70-40% JASPAR ACCATATGTT 64.2% identity Open · Scan
MA1123.1 NN 70-40% JASPAR ATTCCAGATGTTT 64.2% identity Open · Scan
MA0092.1 NN 70-40% JASPAR GGTCTGGCAT 63.2% identity Open · Scan
MA0665.1 NN 70-40% JASPAR AACAGCTGTT 60.7% identity Open · Scan
MA0832.1 NN 70-40% JASPAR GCAACAGCTGTTGT 60.7% identity Open · Scan
MA1568.1 NN 70-40% JASPAR CACCATATGGCG 60.7% identity Open · Scan
MA1638.1 NN 70-40% JASPAR ACCAGATGGC 60.3% identity Open · Scan
MA0091.1 NN 70-40% JASPAR CGACCATCTGTT 57.1% identity Open · Scan
MA0140.1 NN 70-40% JASPAR CTGGTGGGGACAGATAAG 57.1% identity Open · Scan
M04156_2.00 NN 70-40% CisBP AACAGCTGACGC 56.3% identity Open · Scan
MA1618.1 NN 70-40% JASPAR AAACAGATGTTTA 56.3% identity Open · Scan
MA1468.1 NN 70-40% JASPAR AACATATGTC 54.2% identity Open · Scan
M05980_2.00 NN 70-40% CisBP CACAGCTGAC 53.0% identity Open · Scan
M00756_2.00 NN 70-40% CisBP CGCAGCTGTG 51.6% identity Open · Scan
M05962_2.00 NN 70-40% CisBP CCACCTGCC 51.6% identity Open · Scan
MA0048.1 NN 70-40% JASPAR GCGCAGCTGCGT 51.6% identity Open · Scan
MA0623.1 NN 70-40% JASPAR ACCATATGGT 51.6% identity Open · Scan
MA0623.2 NN 70-40% JASPAR GACATATGTC 51.6% identity Open · Scan
MA0669.1 NN 70-40% JASPAR AACATATGTC 51.6% identity Open · Scan
MA1529.1 NN 70-40% JASPAR GGGCCGCAGCTGCGTCCC 51.6% identity Open · Scan
M02784_2.00 NN 70-40% CisBP ACCATATGTT 50.9% identity Open · Scan
MA0817.1 NN 70-40% JASPAR AAACATATGTTT 50.9% identity Open · Scan
M06000_2.00 NN 70-40% CisBP CCAGATGGCACGGACACAACA 50.5% identity Open · Scan
M05952_2.00 NN 70-40% CisBP ACCATCTGCCG 50.0% identity Open · Scan
M05965_2.00 NN 70-40% CisBP AAAAACACCTGCGCC 50.0% identity Open · Scan
MA0607.1 NN 70-40% JASPAR CCATATGT 50.0% identity Open · Scan
MA1467.1 NN 70-40% JASPAR AACAGCTGTC 50.0% identity Open · Scan
ModCRE2
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_tr_Q6NVX3_Q6NVX3_HUMAN:97:145_1nkp_A_1 ModCRE Homology model GCTCCGGGGGGGGCCCCG Region 97-145 · 1 3D model Open · Scan
TFS_tr_Q6NVX3_Q6NVX3_HUMAN:98:148_4h10_A_1 ModCRE Homology model TGCCAAATTTTTTA Region 98-148 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 223 aa
90-152

Region 90-152 2 PWM

Residues
63 aa
Domains
PF00010 · Helix-loop-helix DNA-binding domain
3D models
12 active PDBs · 10 summary rows
Templates
1NKP, 2QL2, 2YPA, 2YPB, 4H10, 5I50, 7SSA, 7Z5I, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
12 active PDB models 10 summary rows
Region 90-15212 models · 10 summary rows
Actions
Predicted = Low DIMER_tr_Q6NVX3_Q6NVX3_HUMAN:105:148_7ssa_L_1 7ssa 105-148 View model · PDB
Predicted = Low DIMER_tr_Q6NVX3_Q6NVX3_HUMAN:97:145_5i50_B_1 5i50 97-145 View model · PDB
Predicted = Low DIMER_tr_Q6NVX3_Q6NVX3_HUMAN:97:148_7z5i_B_1 7z5i 97-148 View model · PDB
Predicted = Low DIMER_tr_Q6NVX3_Q6NVX3_HUMAN:97:148_7z5k_B_1 7z5k 97-148 View model · PDB
Predicted = Low DIMER_tr_Q6NVX3_Q6NVX3_HUMAN:98:145_8osl_N_1 8osl 98-145 View model · PDB
Predicted = Low TFS_tr_Q6NVX3_Q6NVX3_HUMAN:90:152_2ypb_A_1 2ypb 90-152 View model · PDB
Predicted = Low TFS_tr_Q6NVX3_Q6NVX3_HUMAN:91:152_2ypa_A_1 2ypa 91-152 View model · PDB
Predicted = Low TFS_tr_Q6NVX3_Q6NVX3_HUMAN:97:145_1nkp_A_1 1nkp 97-145 View model · PDB
Predicted = Low TFS_tr_Q6NVX3_Q6NVX3_HUMAN:97:148_7z5i_B_1 7z5i 97-148 View model · PDB
Predicted = Low TFS_tr_Q6NVX3_Q6NVX3_HUMAN:97:148_7z5k_B_1 7z5k 97-148 View model · PDB
Predicted = Low TFS_tr_Q6NVX3_Q6NVX3_HUMAN:97:152_2ql2_B_1 2ql2 97-152 View model · PDB
Predicted = Low TFS_tr_Q6NVX3_Q6NVX3_HUMAN:98:148_4h10_A_1 4h10 98-148 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 2ypb 90:157 90 152 P:A · DNA:E,F 57.1% / 65.1% 94 View · PDB TFS_tr_Q6NVX3_Q6NVX3_HUMAN:90:152_2ypb_A_1
2 2ypa 90:157 91 152 P:A · DNA:E,F 56.5% / 64.5% 92 View · PDB TFS_tr_Q6NVX3_Q6NVX3_HUMAN:91:152_2ypa_A_1
3 2ql2 90:157 97 152 P:B · DNA:E,F 50.0% / 66.1% 94 View · PDB TFS_tr_Q6NVX3_Q6NVX3_HUMAN:97:152_2ql2_B_1
1 7z5k 90:157 97,97 148,148 P:A,B · DNA:E,F 44.2% / 59.6% 91,91 View · PDB DIMER_tr_Q6NVX3_Q6NVX3_HUMAN:97:148_7z5k_B_1
2 7z5i 90:157 97,97 148,148 P:A,B · DNA:E,F 44.2% / 59.6% 91,91 View · PDB DIMER_tr_Q6NVX3_Q6NVX3_HUMAN:97:148_7z5i_B_1
4 7z5k 90:157 97,97 148,148 P:A,B · DNA:E,F 44.2% / 59.6% 91,91 View · PDB TFS_tr_Q6NVX3_Q6NVX3_HUMAN:97:148_7z5k_B_1
5 7z5i 90:157 97,97 148,148 P:A,B · DNA:E,F 44.2% / 59.6% 91,91 View · PDB TFS_tr_Q6NVX3_Q6NVX3_HUMAN:97:148_7z5i_B_1
3 7ssa 90:157 105,105 148,148 P:K,L · DNA:I,J 38.6% / 52.3% 59,59 View · PDB DIMER_tr_Q6NVX3_Q6NVX3_HUMAN:105:148_7ssa_L_1
4 5i50 90:157 97,97 145,145 P:A,B · DNA:C,D 34.7% / 53.1% 53,51 View · PDB DIMER_tr_Q6NVX3_Q6NVX3_HUMAN:97:145_5i50_B_1
5 8osl 90:157 98,98 145,145 P:N,P · DNA:I,J 32.7% / 57.1% 16,96 View · PDB DIMER_tr_Q6NVX3_Q6NVX3_HUMAN:98:145_8osl_N_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
97-148PF00010Helix-loop-helix DNA-binding domainoverlaps 90-152