ModCRE DB

Transcription factor

Q6ZMW8

cDNA FLJ16624 fis, clone TESTI4015442, moderately similar to Mus musculus zinc finger homeodomain 4 (Zfh4-pending)

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 1103 aa

18 Generated PWM 17 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)9
MotifPredictionSourceDNA bindingSupportLogoActions
M02108_2.00 NN 70-40% CisBP CCTAATTAG 67.7% identity Open · Scan
M06304_2.00 NN 70-40% CisBP TTAATTA 56.1% identity Open · Scan
M02182_2.00 NN 70-40% CisBP TTAATTAGC 52.6% identity Open · Scan
M01849_2.00 NN 70-40% CisBP ACTAATTAG 51.5% identity Open · Scan
M02105_2.00 NN 70-40% CisBP TTAATTAG 51.1% identity Open · Scan
M05065_2.00 NN 70-40% CisBP TTAACGAG 50.8% identity Open · Scan
M09137_2.00 NN 70-40% CisBP ATTAATTAATTTT 50.8% identity Open · Scan
MA0135.1 NN 70-40% JASPAR AAATTAATTAATC 50.8% identity Open · Scan
MA0704.1 NN 70-40% JASPAR TTAATTAA 50.8% identity Open · Scan
ModCRE9
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_tr_Q6ZMW8_Q6ZMW8_HUMAN:415:475_5hod_A_1 ModCRE Homology model AAAATTAAGGGTAATTTG Region 415-475 · 1 3D model Open · Scan
DIMER_tr_Q6ZMW8_Q6ZMW8_HUMAN:417:470_6a8r_B_1 ModCRE Homology model TGATGACCCC Region 417-470 · 1 3D model Open · Scan
DIMER_tr_Q6ZMW8_Q6ZMW8_HUMAN:417:472_2hdd_B_1 ModCRE Homology model GGCCCTTAATTGACCGG Region 417-472 · 1 3D model Open · Scan
DIMER_tr_Q6ZMW8_Q6ZMW8_HUMAN:418:473_1hdd_D_1 ModCRE Homology model GGCCCTTTATTGGCTCA Region 418-473 · 1 3D model Open · Scan
DIMER_tr_Q6ZMW8_Q6ZMW8_HUMAN:418:473_3hdd_B_1 ModCRE Homology model GGGCCTTAATTGGCTCA Region 418-473 · 1 3D model Open · Scan
TFS_tr_Q6ZMW8_Q6ZMW8_HUMAN:414:470_5zfy_A_1 ModCRE Homology model GGGTAAGCCTATTTAATA Region 414-470 · 1 3D model Open · Scan
TFS_tr_Q6ZMW8_Q6ZMW8_HUMAN:415:475_5hod_A_1 ModCRE Homology model AAAATTAAGGGTAATTTG Region 415-475 · 1 3D model Open · Scan
TFS_tr_Q6ZMW8_Q6ZMW8_HUMAN:418:473_3hdd_B_1 ModCRE Homology model GGGCCTTAATTGGCCAA Region 418-473 · 1 3D model Open · Scan
TFS_tr_Q6ZMW8_Q6ZMW8_HUMAN:93:146_6a8r_B_1 ModCRE Homology model CGATGTCCGA Region 93-146 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 1103 aa
65-149
414-475

Region 65-149 1 PWM

Residues
85 aa
Domains
PF00046 · Homeodomain
3D models
5 active PDBs · 4 summary rows
Templates
5HOD, 6A8R, 8G8E, 8G8G
Sources
Predicted = Low
Scan this region Show models

Region 414-475 8 PWM

Residues
62 aa
Domains
PF00046 · Homeodomain
3D models
12 active PDBs · 6 summary rows
Templates
1AU7, 1HDD, 2HDD, 3A01, 3HDD, 3LNQ, 5HOD, 5ZFY, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
17 active PDB models 10 summary rows
Region 65-1495 models · 4 summary rows
Actions
Predicted = Low DIMER_tr_Q6ZMW8_Q6ZMW8_HUMAN:93:149_5hod_A_1 5hod 93-149 View model · PDB
Predicted = Low TFS_tr_Q6ZMW8_Q6ZMW8_HUMAN:65:149_8g8e_X_1 8g8e 65-149 View model · PDB
Predicted = Low TFS_tr_Q6ZMW8_Q6ZMW8_HUMAN:65:149_8g8g_X_1 8g8g 65-149 View model · PDB
Predicted = Low TFS_tr_Q6ZMW8_Q6ZMW8_HUMAN:93:146_6a8r_B_1 6a8r 93-146 View model · PDB
Predicted = Low TFS_tr_Q6ZMW8_Q6ZMW8_HUMAN:93:149_5hod_A_1 5hod 93-149 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 5hod 65:153 93,94 149,149 P:A,D · DNA:B,C 50.9% / 64.9% 93,96 View · PDB DIMER_tr_Q6ZMW8_Q6ZMW8_HUMAN:93:149_5hod_A_1
1 5hod 65:153 93,94 149,149 P:A,D · DNA:B,C 50.9% / 64.9% 93,96 View · PDB TFS_tr_Q6ZMW8_Q6ZMW8_HUMAN:93:149_5hod_A_1
4 8g8g 65:153 65 149 P:X · DNA:I,J 32.9% / 52.9% 54 View · PDB TFS_tr_Q6ZMW8_Q6ZMW8_HUMAN:65:149_8g8g_X_1
5 8g8e 65:153 65 149 P:X · DNA:I,J 32.9% / 52.9% 54 View · PDB TFS_tr_Q6ZMW8_Q6ZMW8_HUMAN:65:149_8g8e_X_1
Region 414-47512 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_Q6ZMW8_Q6ZMW8_HUMAN:415:475_5hod_A_1 5hod 415-475 View model · PDB
Predicted = Low DIMER_tr_Q6ZMW8_Q6ZMW8_HUMAN:417:470_6a8r_B_1 6a8r 417-470 View model · PDB
Predicted = Low DIMER_tr_Q6ZMW8_Q6ZMW8_HUMAN:417:472_2hdd_B_1 2hdd 417-472 View model · PDB
Predicted = Low DIMER_tr_Q6ZMW8_Q6ZMW8_HUMAN:417:473_3a01_B_1 3a01 417-473 View model · PDB
Predicted = Low DIMER_tr_Q6ZMW8_Q6ZMW8_HUMAN:418:473_1hdd_D_1 1hdd 418-473 View model · PDB
Predicted = Low DIMER_tr_Q6ZMW8_Q6ZMW8_HUMAN:418:473_3hdd_B_1 3hdd 418-473 View model · PDB
Predicted = Low DIMER_tr_Q6ZMW8_Q6ZMW8_HUMAN:420:475_1au7_B_1 1au7 420-475 View model · PDB
Predicted = Low TFS_tr_Q6ZMW8_Q6ZMW8_HUMAN:414:470_5zfy_A_1 5zfy 414-470 View model · PDB
Predicted = Low TFS_tr_Q6ZMW8_Q6ZMW8_HUMAN:415:475_5hod_A_1 5hod 415-475 View model · PDB
Predicted = Low TFS_tr_Q6ZMW8_Q6ZMW8_HUMAN:417:473_3a01_B_1 3a01 417-473 View model · PDB
Predicted = Low TFS_tr_Q6ZMW8_Q6ZMW8_HUMAN:418:473_3hdd_B_1 3hdd 418-473 View model · PDB
Predicted = Low TFS_tr_Q6ZMW8_Q6ZMW8_HUMAN:418:473_3lnq_A_1 3lnq 418-473 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
3 3hdd 65:153 420,418 473,473 P:A,B · DNA:C,D 42.9% / 62.5% 98,100 View · PDB DIMER_tr_Q6ZMW8_Q6ZMW8_HUMAN:418:473_3hdd_B_1
5 1hdd 65:153 418,418 473,473 P:C,D · DNA:A,B 42.9% / 62.5% 98,98 View · PDB DIMER_tr_Q6ZMW8_Q6ZMW8_HUMAN:418:473_1hdd_D_1
3 3lnq 65:153 418 473 P:A · DNA:B,C 42.9% / 60.7% 96 View · PDB TFS_tr_Q6ZMW8_Q6ZMW8_HUMAN:418:473_3lnq_A_1
2 3a01 65:153 414,417 473,473 P:A,B · DNA:C,D 42.1% / 61.4% 76,100 View · PDB DIMER_tr_Q6ZMW8_Q6ZMW8_HUMAN:417:473_3a01_B_1
2 3a01 65:153 414,417 473,473 P:A,B · DNA:C,D 42.1% / 61.4% 76,100 View · PDB TFS_tr_Q6ZMW8_Q6ZMW8_HUMAN:417:473_3a01_B_1
4 1au7 65:153 420,420 475,475 P:A,B · DNA:C,D 37.5% / 55.4% 43,43 View · PDB DIMER_tr_Q6ZMW8_Q6ZMW8_HUMAN:420:475_1au7_B_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
93-149PF00046Homeodomainoverlaps 65-149
417-473PF00046Homeodomainoverlaps 414-475