ModCRE DB

Transcription factor

Q76KX8 - ZNF534

Zinc finger protein 534 (KRAB domain only protein 3)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 674 aa

71 Generated PWM 11 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known1
MotifPredictionSourceDNA bindingSupportLogoActions
M07751_2.00 Known CisBP AGGTTCTCGCCCCCC Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)61
MotifPredictionSourceDNA bindingSupportLogoActions
M07764_2.00 NN 70-40% CisBP CTGCACTCTCCCCTTCCCCCCCTCCCC 67.1% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 64.7% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 63.5% identity Open · Scan
MA1597.1 NN 70-40% JASPAR CCCAGGGAAGCCATTTC 63.3% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 62.3% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 62.3% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 61.1% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 61.1% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 61.1% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 61.1% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 61.1% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 60.9% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 60.1% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 60.0% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 60.0% identity Open · Scan
M08985_2.00 NN 70-40% CisBP TGAGGACCTACTGTGTGCC 59.3% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 59.2% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 59.2% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 59.0% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 58.6% identity Open · Scan
M08887_2.00 NN 70-40% CisBP CCTCCTCCAGGAAGCCTTCCCTGA 56.8% identity Open · Scan
M08375_2.00 NN 70-40% CisBP TTCCCCATTGGCTACTGCACCGGTCCT 56.7% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 56.5% identity Open · Scan
M07753_2.00 NN 70-40% CisBP TGCATTCCTTGGCTTGTG 56.2% identity Open · Scan
M04613_2.00 NN 70-40% CisBP CTCATGTGCTAATTACAAA 55.7% identity Open · Scan
M08267_2.00 NN 70-40% CisBP CAGTTTCATTTTCC 55.6% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 55.6% identity Open · Scan
M07683_2.00 NN 70-40% CisBP GTGGGAAAGCCT 55.1% identity Open · Scan
MA1601.1 NN 70-40% JASPAR ATGTGGGAAA 55.1% identity Open · Scan
M08334_2.00 NN 70-40% CisBP TTTGTTTTTTTCTGATTGCTTTTTACTTAT 54.9% identity Open · Scan
M08252_2.00 NN 70-40% CisBP CCGGCTCCAGCACCC 54.8% identity Open · Scan
MA1602.1 NN 70-40% JASPAR CGTCTACACGGG 54.8% identity Open · Scan
M08395_2.00 NN 70-40% CisBP GCTGCCTACTCTTCC 54.7% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 54.5% identity Open · Scan
M07699_2.00 NN 70-40% CisBP GGTTTAT 54.5% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 54.4% identity Open · Scan
M07649_2.00 NN 70-40% CisBP CCCCCCCCCCCCTCAGGAATGCC 54.1% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 54.0% identity Open · Scan
M07581_2.00 NN 70-40% CisBP TCCCCTGTGCTTCTCTCCCCT 53.8% identity Open · Scan
M07759_2.00 NN 70-40% CisBP GGAGCGCCCCTGCCCGGC 53.2% identity Open · Scan
M04621_2.00 NN 70-40% CisBP AGCAATTCCGCTCA 53.1% identity Open · Scan
M01442_2.00 NN 70-40% CisBP ACCCCACATT 52.5% identity Open · Scan
MA1154.1 NN 70-40% JASPAR CTTTCCCACAACACGAC 52.5% identity Open · Scan
M00019_2.00 NN 70-40% CisBP ACCCCTAATT 52.0% identity Open · Scan
M01531_2.00 NN 70-40% CisBP CCCCCCCTAAAT 52.0% identity Open · Scan
M08373_2.00 NN 70-40% CisBP CCCCCTGGCTCTTCCTCT 51.9% identity Open · Scan
M10391_2.00 NN 70-40% CisBP TACCCCACATTTATTTA 51.7% identity Open · Scan
M00217_2.00 NN 70-40% CisBP TTACTCAATAT 51.4% identity Open · Scan
M04465_2.00 NN 70-40% CisBP GTGATTCTTATCTTATCCTT 51.2% identity Open · Scan
M08859_2.00 NN 70-40% CisBP CATTTTTTCCTCCTAGGCCT 51.0% identity Open · Scan
M01456_2.00 NN 70-40% CisBP GTGATCGGCG 50.9% identity Open · Scan
M01474_2.00 NN 70-40% CisBP CGCCGATCAC 50.9% identity Open · Scan
M07562_2.00 NN 70-40% CisBP GAAAAAAAC 50.9% identity Open · Scan
M00609_2.00 NN 70-40% CisBP GGAAGCCCTA 50.4% identity Open · Scan
M07633_2.00 NN 70-40% CisBP CTCTCGTTGTGCCTTTGCCAT 50.4% identity Open · Scan
M01044_2.00 NN 70-40% CisBP TCTCTCTTTC 50.3% identity Open · Scan
M07648_2.00 NN 70-40% CisBP GCTTGCAAAAAAAATTTAACTCCCAGCTC 50.2% identity Open · Scan
MA1656.1 NN 70-40% JASPAR CCAAGCCCAACCAG 50.2% identity Open · Scan
M00779_2.00 NN 70-40% CisBP GCCACGCCCA 50.0% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 50.0% identity Open · Scan
M08867_2.00 NN 70-40% CisBP CACCCCCTG 50.0% identity Open · Scan
ModCRE9
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_sp_Q76KX8_ZN534_HUMAN:236:389_2i13_A_1 ModCRE Homology model TTGAAGAGGGAGGTAGTCCTA Region 236-389 · 1 3D model Open · Scan
TFS_sp_Q76KX8_ZN534_HUMAN:338:614_5v3j_E_1 ModCRE Homology model GGGGACCCTTCCCCCCCGGGGGGGGG Region 338-614 · 1 3D model Open · Scan
TFS_sp_Q76KX8_ZN534_HUMAN:338:614_5v3m_C_1 ModCRE Homology model CCCCCCCGGCCCCCCCCCCCCCGCCG Region 338-614 · 1 3D model Open · Scan
TFS_sp_Q76KX8_ZN534_HUMAN:364:642_5wjq_D_1 ModCRE Homology model CCGGCACGCCCCCCCCCCCCCCCCCCCC Region 364-642 · 1 3D model Open · Scan
TFS_sp_Q76KX8_ZN534_HUMAN:645:674_2i13_A_1 ModCRE Homology model CTTACTCTAGAA Region 645-674 · 1 3D model Open · Scan
TFS_sp_Q76KX8_ZN534_HUMAN:645:674_5egb_A_1 ModCRE Homology model ATGAAAAAGG Region 645-674 · 1 3D model Open · Scan
TFS_sp_Q76KX8_ZN534_HUMAN:645:674_5ei9_E_1 ModCRE Homology model AAGCAACA Region 645-674 · 1 3D model Open · Scan
TFS_sp_Q76KX8_ZN534_HUMAN:645:674_5wjq_D_1 ModCRE Homology model TGGGGTTTTTAT Region 645-674 · 1 3D model Open · Scan
TFS_sp_Q76KX8_ZN534_HUMAN:646:674_5eh2_F_1 ModCRE Homology model TGCTGCAAGC Region 646-674 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 674 aa
236-642
645-674

Region 236-642 4 PWM

Residues
407 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
6 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models

Region 645-674 5 PWM

Residues
30 aa
Domains
No overlapping PFAM annotation recorded
3D models
5 active PDBs
Templates
2I13, 5EGB, 5EH2, 5EI9, 5WJQ
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
11 active PDB models 6 summary rows
Region 236-6426 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_Q76KX8_ZN534_HUMAN:533:584_1llm_D_1 1llm 533-584 View model · PDB
Predicted = Low TFS_sp_Q76KX8_ZN534_HUMAN:236:389_2i13_A_1 2i13 236-389 View model · PDB
Predicted = Low TFS_sp_Q76KX8_ZN534_HUMAN:311:609_7w1m_H_1 7w1m 311-609 View model · PDB
Predicted = Low TFS_sp_Q76KX8_ZN534_HUMAN:338:614_5v3j_E_1 5v3j 338-614 View model · PDB
Predicted = Low TFS_sp_Q76KX8_ZN534_HUMAN:338:614_5v3m_C_1 5v3m 338-614 View model · PDB
Predicted = Low TFS_sp_Q76KX8_ZN534_HUMAN:364:642_5wjq_D_1 5wjq 364-642 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
5 2i13 236:668 236 389 P:A · DNA:C,D 55.8% / 66.2% 100 View · PDB TFS_sp_Q76KX8_ZN534_HUMAN:236:389_2i13_A_1
1 5wjq 236:668 364 642 P:D · DNA:A,B 55.6% / 68.5% 99 View · PDB TFS_sp_Q76KX8_ZN534_HUMAN:364:642_5wjq_D_1
2 5v3m 236:668 338 614 P:C · DNA:A,B 55.2% / 68.6% 100 View · PDB TFS_sp_Q76KX8_ZN534_HUMAN:338:614_5v3m_C_1
3 5v3j 236:668 338 614 P:E · DNA:A,B 55.2% / 68.6% 100 View · PDB TFS_sp_Q76KX8_ZN534_HUMAN:338:614_5v3j_E_1
1 1llm 236:668 533,533 584,584 P:C,D · DNA:A,B 46.2% / 65.4% 59,61 View · PDB DIMER_sp_Q76KX8_ZN534_HUMAN:533:584_1llm_D_1
4 7w1m 236:668 311 609 P:H · DNA:F,G 36.4% / 52.6% 92 View · PDB TFS_sp_Q76KX8_ZN534_HUMAN:311:609_7w1m_H_1
Region 645-6745 models
Actions
Predicted = Low TFS_sp_Q76KX8_ZN534_HUMAN:645:674_2i13_A_1 2i13 645-674 View model · PDB
Predicted = Low TFS_sp_Q76KX8_ZN534_HUMAN:645:674_5egb_A_1 5egb 645-674 View model · PDB
Predicted = Low TFS_sp_Q76KX8_ZN534_HUMAN:645:674_5ei9_E_1 5ei9 645-674 View model · PDB
Predicted = Low TFS_sp_Q76KX8_ZN534_HUMAN:645:674_5wjq_D_1 5wjq 645-674 View model · PDB
Predicted = Low TFS_sp_Q76KX8_ZN534_HUMAN:646:674_5eh2_F_1 5eh2 646-674 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
8-48PF01352KRAB boxNo overlap with loaded model regions
227-249PF00096Zinc finger, C2H2 typeoverlaps 236-642
259-277PF00096Zinc finger, C2H2 typeoverlaps 236-642
311-333PF00096Zinc finger, C2H2 typeoverlaps 236-642
339-361PF00096Zinc finger, C2H2 typeoverlaps 236-642
367-389PF00096Zinc finger, C2H2 typeoverlaps 236-642
395-417PF00096Zinc finger, C2H2 typeoverlaps 236-642
423-445PF00096Zinc finger, C2H2 typeoverlaps 236-642
479-501PF00096Zinc finger, C2H2 typeoverlaps 236-642
507-529PF00096Zinc finger, C2H2 typeoverlaps 236-642
535-557PF00096Zinc finger, C2H2 typeoverlaps 236-642
563-585PF00096Zinc finger, C2H2 typeoverlaps 236-642
591-613PF00096Zinc finger, C2H2 typeoverlaps 236-642
619-641PF00096Zinc finger, C2H2 typeoverlaps 236-642