ModCRE DB

Transcription factor

Q7LFL8 - CXXC5

CXXC-type zinc finger protein 5 (CF5) (Putative MAPK-activating protein PM08) (Putative NF-kappa-B-activating protein 102) (Retinoid-inducible nuclear factor) (RINF)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 322 aa

7 Generated PWM 11 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known1
MotifPredictionSourceDNA bindingSupportLogoActions
M01210_2.00 Known CisBP ATTACGTG Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE6
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q7LFL8_CXXC5_HUMAN:270:296_1a6y_A_1 ModCRE Homology model ACCATGTGGACCGGGGG Region 270-296 · 1 3D model Open · Scan
DIMER_sp_Q7LFL8_CXXC5_HUMAN:270:296_1ga5_B_1 ModCRE Homology model CCCATTGTGACCAGGGT Region 270-296 · 1 3D model Open · Scan
DIMER_sp_Q7LFL8_CXXC5_HUMAN:270:296_1hlz_A_1 ModCRE Homology model AAAGGTGGGACCTGGGG Region 270-296 · 1 3D model Open · Scan
DIMER_sp_Q7LFL8_CXXC5_HUMAN:277:299_1hcq_B_1 ModCRE Homology model AGATGTATCATGAGTCT Region 277-299 · 1 3D model Open · Scan
DIMER_sp_Q7LFL8_CXXC5_HUMAN:277:299_4aa6_A_1 ModCRE Homology model AGACTCTGTCACATGGG Region 277-299 · 1 3D model Open · Scan
TFS_sp_Q7LFL8_CXXC5_HUMAN:258:303_5vc9_C_1 ModCRE Homology model GCCCGCGCGGTG Region 258-303 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 322 aa
258-304

Region 258-304 6 PWM

Residues
47 aa
Domains
PF02008 · CXXC zinc finger domain
3D models
11 active PDBs · 10 summary rows
Templates
1A6Y, 1GA5, 1HCQ, 1HLZ, 2KKF, 3QMH, 4AA6, 4NW3, ...
Sources
Predicted = Low
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
11 active PDB models 10 summary rows
Region 258-30411 models · 10 summary rows
Actions
Predicted = Low DIMER_sp_Q7LFL8_CXXC5_HUMAN:270:296_1a6y_A_1 1a6y 270-296 View model · PDB
Predicted = Low DIMER_sp_Q7LFL8_CXXC5_HUMAN:270:296_1ga5_B_1 1ga5 270-296 View model · PDB
Predicted = Low DIMER_sp_Q7LFL8_CXXC5_HUMAN:270:296_1hlz_A_1 1hlz 270-296 View model · PDB
Predicted = Low DIMER_sp_Q7LFL8_CXXC5_HUMAN:277:299_1hcq_B_1 1hcq 277-299 View model · PDB
Predicted = Low DIMER_sp_Q7LFL8_CXXC5_HUMAN:277:299_4aa6_A_1 4aa6 277-299 View model · PDB
Predicted = Low TFS_sp_Q7LFL8_CXXC5_HUMAN:258:300_4nw3_A_1 4nw3 258-300 View model · PDB
Predicted = Low TFS_sp_Q7LFL8_CXXC5_HUMAN:258:301_5w9s_C_1 5w9s 258-301 View model · PDB
Predicted = Low TFS_sp_Q7LFL8_CXXC5_HUMAN:258:303_5vc9_C_1 5vc9 258-303 View model · PDB
Predicted = Low TFS_sp_Q7LFL8_CXXC5_HUMAN:258:304_2kkf_A_1 2kkf 258-304 View model · PDB
Predicted = Low TFS_sp_Q7LFL8_CXXC5_HUMAN:259:302_6asd_C_1 6asd 259-302 View model · PDB
Predicted = Low TFS_sp_Q7LFL8_CXXC5_HUMAN:261:285_3qmh_A_1 3qmh 261-285 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 5w9s 258:304 258 301 P:C · DNA:A,B 100.0% / 100.0% 100 View · PDB TFS_sp_Q7LFL8_CXXC5_HUMAN:258:301_5w9s_C_1
2 6asd 258:304 259 302 P:C · DNA:A,B 68.2% / 84.1% 100 View · PDB TFS_sp_Q7LFL8_CXXC5_HUMAN:259:302_6asd_C_1
5 3qmh 258:304 261 285 P:A · DNA:B,C 44.0% / 56.0% 47 View · PDB TFS_sp_Q7LFL8_CXXC5_HUMAN:261:285_3qmh_A_1
1 4aa6 258:304 277,277 299,299 P:A,B · DNA:C,D 43.5% / 65.2% 33,33 View · PDB DIMER_sp_Q7LFL8_CXXC5_HUMAN:277:299_4aa6_A_1
2 1hcq 258:304 277,277 299,299 P:A,B · DNA:C,D 43.5% / 65.2% 31,32 View · PDB DIMER_sp_Q7LFL8_CXXC5_HUMAN:277:299_1hcq_B_1
3 1ga5 258:304 270,270 296,296 P:A,B · DNA:C,D 37.0% / 55.6% 32,34 View · PDB DIMER_sp_Q7LFL8_CXXC5_HUMAN:270:296_1ga5_B_1
4 1hlz 258:304 270,270 296,296 P:A,B · DNA:C,D 37.0% / 55.6% 33,33 View · PDB DIMER_sp_Q7LFL8_CXXC5_HUMAN:270:296_1hlz_A_1
5 1a6y 258:304 270,270 296,296 P:A,B · DNA:C,D 37.0% / 55.6% 34,32 View · PDB DIMER_sp_Q7LFL8_CXXC5_HUMAN:270:296_1a6y_A_1
3 2kkf 258:304 258 304 P:A · DNA:B,C 34.0% / 52.8% 82 View · PDB TFS_sp_Q7LFL8_CXXC5_HUMAN:258:304_2kkf_A_1
4 4nw3 258:304 258 300 P:A · DNA:B,C 32.7% / 53.1% 84 View · PDB TFS_sp_Q7LFL8_CXXC5_HUMAN:258:300_4nw3_A_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
257-296PF02008CXXC zinc finger domainoverlaps 258-304