ModCRE DB

Transcription factor

Q7RTU5 - ASCL5

Achaete-scute homolog 5 (ASH-5) (hASH5) (Class A basic helix-loop-helix protein 47) (bHLHa47)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 206 aa

18 Generated PWM 13 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)11
MotifPredictionSourceDNA bindingSupportLogoActions
MA1100.1 NN 70-40% JASPAR GCAGCAGCTGGCG 59.3% identity Open · Scan
MA0816.1 NN 70-40% JASPAR AGCAGCTGCT 58.6% identity Open · Scan
MA0500.1 NN 70-40% JASPAR GACAGCTGCAG 51.9% identity Open · Scan
MA0500.2 NN 70-40% JASPAR CAGCAGCTGCTG 51.9% identity Open · Scan
M00756_2.00 NN 70-40% CisBP CGCAGCTGTG 51.0% identity Open · Scan
MA0048.1 NN 70-40% JASPAR GCGCAGCTGCGT 51.0% identity Open · Scan
MA1529.1 NN 70-40% JASPAR GGGCCGCAGCTGCGTCCC 51.0% identity Open · Scan
MA1641.1 NN 70-40% JASPAR GAACAGCTGTTC 51.0% identity Open · Scan
M04156_2.00 NN 70-40% CisBP AACAGCTGACGC 50.0% identity Open · Scan
MA1485.1 NN 70-40% JASPAR GCAACAGCTGTTAC 50.0% identity Open · Scan
MA1618.1 NN 70-40% JASPAR AAACAGATGTTTA 50.0% identity Open · Scan
ModCRE7
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q7RTU5_ASCL5_HUMAN:159:213_2ql2_B_1 ModCRE Homology model CCCAACATATGGCTCC Region 159-213 · 1 3D model Open · Scan
DIMER_sp_Q7RTU5_ASCL5_HUMAN:161:212_2ypa_A_1 ModCRE Homology model CCCACGTGGGG Region 161-212 · 1 3D model Open · Scan
DIMER_sp_Q7RTU5_ASCL5_HUMAN:161:212_2ypb_A_1 ModCRE Homology model CCCAGGTGGGC Region 161-212 · 1 3D model Open · Scan
DIMER_sp_Q7RTU5_ASCL5_HUMAN:163:211_1mdy_A_1 ModCRE Homology model GACACAGCTGTGTC Region 163-211 · 1 3D model Open · Scan
DIMER_sp_Q7RTU5_ASCL5_HUMAN:188:208_1am9_B_1 ModCRE Homology model ACAAGGGGGCCCGCGTGGGCTCGC Region 188-208 · 1 3D model Open · Scan
TFS_sp_Q7RTU5_ASCL5_HUMAN:159:213_2ql2_B_1 ModCRE Homology model GCCCACAGCTGCTGCA Region 159-213 · 1 3D model Open · Scan
TFS_sp_Q7RTU5_ASCL5_HUMAN:163:211_1mdy_A_1 ModCRE Homology model GAGAGTACTCTCTA Region 163-211 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 206 aa
159-213

Region 159-213 7 PWM

Residues
55 aa
Domains
No overlapping PFAM annotation recorded
3D models
13 active PDBs · 10 summary rows
Templates
1AM9, 1MDY, 2QL2, 2YPA, 2YPB, 7Z5I, 7Z5K
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
13 active PDB models 10 summary rows
Region 159-21313 models · 10 summary rows
Actions
Predicted = Low DIMER_sp_Q7RTU5_ASCL5_HUMAN:159:213_2ql2_B_1 2ql2 159-213 View model · PDB
Predicted = Low DIMER_sp_Q7RTU5_ASCL5_HUMAN:161:212_2ypa_A_1 2ypa 161-212 View model · PDB
Predicted = Low DIMER_sp_Q7RTU5_ASCL5_HUMAN:161:212_2ypb_A_1 2ypb 161-212 View model · PDB
Predicted = Low DIMER_sp_Q7RTU5_ASCL5_HUMAN:163:209_7z5i_B_1 7z5i 163-209 View model · PDB
Predicted = Low DIMER_sp_Q7RTU5_ASCL5_HUMAN:163:210_7z5k_B_1 7z5k 163-210 View model · PDB
Predicted = Low DIMER_sp_Q7RTU5_ASCL5_HUMAN:163:211_1mdy_A_1 1mdy 163-211 View model · PDB
Predicted = Low DIMER_sp_Q7RTU5_ASCL5_HUMAN:188:208_1am9_B_1 1am9 188-208 View model · PDB
Predicted = Low TFS_sp_Q7RTU5_ASCL5_HUMAN:159:213_2ql2_B_1 2ql2 159-213 View model · PDB
Predicted = Low TFS_sp_Q7RTU5_ASCL5_HUMAN:161:212_2ypa_A_1 2ypa 161-212 View model · PDB
Predicted = Low TFS_sp_Q7RTU5_ASCL5_HUMAN:161:212_2ypb_A_1 2ypb 161-212 View model · PDB
Predicted = Low TFS_sp_Q7RTU5_ASCL5_HUMAN:163:209_7z5i_B_1 7z5i 163-209 View model · PDB
Predicted = Low TFS_sp_Q7RTU5_ASCL5_HUMAN:163:210_7z5k_B_1 7z5k 163-210 View model · PDB
Predicted = Low TFS_sp_Q7RTU5_ASCL5_HUMAN:163:211_1mdy_A_1 1mdy 163-211 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
3 7z5k 159:213 163,163 209,210 P:A,B · DNA:E,F 50.0% / 64.6% 82,83 View · PDB DIMER_sp_Q7RTU5_ASCL5_HUMAN:163:210_7z5k_B_1
3 7z5k 159:213 163,163 209,210 P:A,B · DNA:E,F 50.0% / 64.6% 82,83 View · PDB TFS_sp_Q7RTU5_ASCL5_HUMAN:163:210_7z5k_B_1
5 1mdy 159:213 163,163 211,211 P:A,B · DNA:E,F 49.0% / 63.3% 70,77 View · PDB DIMER_sp_Q7RTU5_ASCL5_HUMAN:163:211_1mdy_A_1
4 7z5i 159:213 163,163 209,209 P:A,B · DNA:E,F 48.9% / 63.8% 82,82 View · PDB DIMER_sp_Q7RTU5_ASCL5_HUMAN:163:209_7z5i_B_1
5 7z5i 159:213 163,163 209,209 P:A,B · DNA:E,F 48.9% / 63.8% 82,82 View · PDB TFS_sp_Q7RTU5_ASCL5_HUMAN:163:209_7z5i_B_1
1 2ypa 159:213 161,161 212,209 P:A,B · DNA:E,F 46.2% / 65.4% 77,67 View · PDB DIMER_sp_Q7RTU5_ASCL5_HUMAN:161:212_2ypa_A_1
1 2ypa 159:213 161,161 212,209 P:A,B · DNA:E,F 46.2% / 65.4% 77,67 View · PDB TFS_sp_Q7RTU5_ASCL5_HUMAN:161:212_2ypa_A_1
2 2ypb 159:213 161,161 212,209 P:A,B · DNA:E,F 46.2% / 65.4% 77,66 View · PDB DIMER_sp_Q7RTU5_ASCL5_HUMAN:161:212_2ypb_A_1
2 2ypb 159:213 161,161 212,209 P:A,B · DNA:E,F 46.2% / 65.4% 77,66 View · PDB TFS_sp_Q7RTU5_ASCL5_HUMAN:161:212_2ypb_A_1
4 2ql2 159:213 159 213 P:B · DNA:E,F 43.6% / 56.4% 93 View · PDB TFS_sp_Q7RTU5_ASCL5_HUMAN:159:213_2ql2_B_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
87-136PF00010Helix-loop-helix DNA-binding domainNo overlap with loaded model regions