ModCRE DB

Transcription factor

Q7RTU7 - SCX

Basic helix-loop-helix transcription factor scleraxis (Class A basic helix-loop-helix protein 41) (bHLHa41) (Class A basic helix-loop-helix protein 48) (bHLHa48)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 201 aa

47 Generated PWM 12 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)35
MotifPredictionSourceDNA bindingSupportLogoActions
M06000_2.00 NN 70-40% CisBP CCAGATGGCACGGACACAACA 62.5% identity Open · Scan
M00756_2.00 NN 70-40% CisBP CGCAGCTGTG 61.2% identity Open · Scan
MA0048.1 NN 70-40% JASPAR GCGCAGCTGCGT 61.2% identity Open · Scan
MA1529.1 NN 70-40% JASPAR GGGCCGCAGCTGCGTCCC 61.2% identity Open · Scan
M01718_2.00 NN 70-40% CisBP AACATATGGT 60.0% identity Open · Scan
MA0633.1 NN 70-40% JASPAR ACCATATGTT 60.0% identity Open · Scan
MA1123.1 NN 70-40% JASPAR ATTCCAGATGTTT 60.0% identity Open · Scan
M03606_2.00 NN 70-40% CisBP CCACACGACGCA 59.6% identity Open · Scan
MA0091.1 NN 70-40% JASPAR CGACCATCTGTT 58.8% identity Open · Scan
MA0140.1 NN 70-40% JASPAR CTGGTGGGGACAGATAAG 58.8% identity Open · Scan
MA0665.1 NN 70-40% JASPAR AACAGCTGTT 57.1% identity Open · Scan
MA0832.1 NN 70-40% JASPAR GCAACAGCTGTTGT 57.1% identity Open · Scan
MA1568.1 NN 70-40% JASPAR CACCATATGGCG 57.1% identity Open · Scan
MA1638.1 NN 70-40% JASPAR ACCAGATGGC 57.1% identity Open · Scan
M05965_2.00 NN 70-40% CisBP AAAAACACCTGCGCC 55.1% identity Open · Scan
MA0092.1 NN 70-40% JASPAR GGTCTGGCAT 55.0% identity Open · Scan
M05986_2.00 NN 70-40% CisBP ACCGCACCATCTGTC 54.3% identity Open · Scan
MA0818.1 NN 70-40% JASPAR ACCATATGTT 54.3% identity Open · Scan
M05980_2.00 NN 70-40% CisBP CACAGCTGAC 52.6% identity Open · Scan
MA1472.1 NN 70-40% JASPAR AACAGCTGTT 51.3% identity Open · Scan
M04210_2.00 NN 70-40% CisBP AGCAGCTGCC 50.9% identity Open · Scan
MA0816.1 NN 70-40% JASPAR AGCAGCTGCT 50.9% identity Open · Scan
M04156_2.00 NN 70-40% CisBP AACAGCTGACGC 50.8% identity Open · Scan
M05952_2.00 NN 70-40% CisBP ACCATCTGCCG 50.8% identity Open · Scan
M05962_2.00 NN 70-40% CisBP CCACCTGCC 50.8% identity Open · Scan
MA1468.1 NN 70-40% JASPAR AACATATGTC 50.8% identity Open · Scan
MA1618.1 NN 70-40% JASPAR AAACAGATGTTTA 50.8% identity Open · Scan
M03621_2.00 NN 70-40% CisBP AAAACAGCTGTTTT 50.0% identity Open · Scan
MA0461.1 NN 70-40% JASPAR CAGATGGC 50.0% identity Open · Scan
MA0607.1 NN 70-40% JASPAR CCATATGT 50.0% identity Open · Scan
MA0623.1 NN 70-40% JASPAR ACCATATGGT 50.0% identity Open · Scan
MA0623.2 NN 70-40% JASPAR GACATATGTC 50.0% identity Open · Scan
MA0827.1 NN 70-40% JASPAR ACCATATGTT 50.0% identity Open · Scan
MA1467.1 NN 70-40% JASPAR AACAGCTGTC 50.0% identity Open · Scan
MA1485.1 NN 70-40% JASPAR GCAACAGCTGTTAC 50.0% identity Open · Scan
ModCRE12
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q7RTU7_SCX_HUMAN:67:124_5i50_B_1 ModCRE Homology model TGGGGTGACACGTGGGGAGGGA Region 67-124 · 1 3D model Open · Scan
DIMER_sp_Q7RTU7_SCX_HUMAN:76:127_7z5i_B_1 ModCRE Homology model TATATGCATATGGCTAGT Region 76-127 · 1 3D model Open · Scan
DIMER_sp_Q7RTU7_SCX_HUMAN:76:127_7z5k_B_1 ModCRE Homology model TTTAAACATATGGCTAGT Region 76-127 · 1 3D model Open · Scan
DIMER_sp_Q7RTU7_SCX_HUMAN:76:131_1mdy_B_1 ModCRE Homology model TAGCCATATGTTAC Region 76-131 · 1 3D model Open · Scan
DIMER_sp_Q7RTU7_SCX_HUMAN:84:127_7ssa_L_1 ModCRE Homology model TCACGTGCGCACGCCACCATCAACTGATAACATAAGTGTCAATTGATACTAAGCACGAAACGCATCCCATCTGAAAAACATTAGA Region 84-127 · 1 3D model Open · Scan
DIMER_sp_Q7RTU7_SCX_HUMAN:84:127_8ow0_B_1 ModCRE Homology model TCCACCCGCGTCCTCCGG Region 84-127 · 1 3D model Open · Scan
TFS_sp_Q7RTU7_SCX_HUMAN:67:124_5i50_B_1 ModCRE Homology model TCCCTCCCCACGTGTCACCCCA Region 67-124 · 1 3D model Open · Scan
TFS_sp_Q7RTU7_SCX_HUMAN:76:124_8ott_M_1 ModCRE Homology model CCTCTCGGTGCGCGTCCTGAGCCTGGATCCTAGGCTCCCTGTCATGCGCCTTAGAAGGCTGGGTCTCACTAGCACTTCCGCCCCCTCTTGGGA Region 76-124 · 1 3D model Open · Scan
TFS_sp_Q7RTU7_SCX_HUMAN:76:131_1mdy_A_1 ModCRE Homology model CAGCCAGCTGTTAA Region 76-131 · 1 3D model Open · Scan
TFS_sp_Q7RTU7_SCX_HUMAN:76:131_2ql2_B_1 ModCRE Homology model TTGGCCATATTTTGCA Region 76-131 · 1 3D model Open · Scan
TFS_sp_Q7RTU7_SCX_HUMAN:76:131_2ypa_A_1 ModCRE Homology model GTGCATATGGT Region 76-131 · 1 3D model Open · Scan
TFS_sp_Q7RTU7_SCX_HUMAN:76:131_2ypb_A_1 ModCRE Homology model CGCCATGTGGG Region 76-131 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 201 aa
67-131

Region 67-131 12 PWM

Residues
65 aa
Domains
PF00010 · Helix-loop-helix DNA-binding domain
3D models
12 active PDBs · 10 summary rows
Templates
1MDY, 2QL2, 2YPA, 2YPB, 5I50, 7SSA, 7Z5I, 7Z5K, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
12 active PDB models 10 summary rows
Region 67-13112 models · 10 summary rows
Actions
Predicted = Low DIMER_sp_Q7RTU7_SCX_HUMAN:67:124_5i50_B_1 5i50 67-124 View model · PDB
Predicted = Low DIMER_sp_Q7RTU7_SCX_HUMAN:76:127_7z5i_B_1 7z5i 76-127 View model · PDB
Predicted = Low DIMER_sp_Q7RTU7_SCX_HUMAN:76:127_7z5k_B_1 7z5k 76-127 View model · PDB
Predicted = Low DIMER_sp_Q7RTU7_SCX_HUMAN:76:131_1mdy_B_1 1mdy 76-131 View model · PDB
Predicted = Low DIMER_sp_Q7RTU7_SCX_HUMAN:84:127_7ssa_L_1 7ssa 84-127 View model · PDB
Predicted = Low DIMER_sp_Q7RTU7_SCX_HUMAN:84:127_8ow0_B_1 8ow0 84-127 View model · PDB
Predicted = Low TFS_sp_Q7RTU7_SCX_HUMAN:67:124_5i50_B_1 5i50 67-124 View model · PDB
Predicted = Low TFS_sp_Q7RTU7_SCX_HUMAN:76:124_8ott_M_1 8ott 76-124 View model · PDB
Predicted = Low TFS_sp_Q7RTU7_SCX_HUMAN:76:131_1mdy_A_1 1mdy 76-131 View model · PDB
Predicted = Low TFS_sp_Q7RTU7_SCX_HUMAN:76:131_2ql2_B_1 2ql2 76-131 View model · PDB
Predicted = Low TFS_sp_Q7RTU7_SCX_HUMAN:76:131_2ypa_A_1 2ypa 76-131 View model · PDB
Predicted = Low TFS_sp_Q7RTU7_SCX_HUMAN:76:131_2ypb_A_1 2ypb 76-131 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 2ypb 67:136 76 131 P:A · DNA:E,F 55.4% / 66.1% 83 View · PDB TFS_sp_Q7RTU7_SCX_HUMAN:76:131_2ypb_A_1
2 2ypa 67:136 76 131 P:A · DNA:E,F 55.4% / 66.1% 83 View · PDB TFS_sp_Q7RTU7_SCX_HUMAN:76:131_2ypa_A_1
3 2ql2 67:136 76 131 P:B · DNA:E,F 50.0% / 66.1% 94 View · PDB TFS_sp_Q7RTU7_SCX_HUMAN:76:131_2ql2_B_1
2 7z5k 67:136 76,76 127,127 P:A,B · DNA:E,F 42.3% / 53.8% 91,91 View · PDB DIMER_sp_Q7RTU7_SCX_HUMAN:76:127_7z5k_B_1
3 7z5i 67:136 76,76 127,127 P:A,B · DNA:E,F 42.3% / 53.8% 91,91 View · PDB DIMER_sp_Q7RTU7_SCX_HUMAN:76:127_7z5i_B_1
4 8ott 67:136 76 124 P:M · DNA:I,J 38.8% / 55.1% 92 View · PDB TFS_sp_Q7RTU7_SCX_HUMAN:76:124_8ott_M_1
4 7ssa 67:136 84,84 127,127 P:K,L · DNA:I,J 38.6% / 50.0% 59,59 View · PDB DIMER_sp_Q7RTU7_SCX_HUMAN:84:127_7ssa_L_1
5 8ow0 67:136 84,84 127,127 P:A,B · DNA:D,E 38.6% / 50.0% 39,37 View · PDB DIMER_sp_Q7RTU7_SCX_HUMAN:84:127_8ow0_B_1
1 5i50 67:136 76,67 124,124 P:A,B · DNA:C,D 36.2% / 50.0% 53,60 View · PDB DIMER_sp_Q7RTU7_SCX_HUMAN:67:124_5i50_B_1
5 5i50 67:136 76,67 124,124 P:A,B · DNA:C,D 36.2% / 50.0% 53,60 View · PDB TFS_sp_Q7RTU7_SCX_HUMAN:67:124_5i50_B_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
76-127PF00010Helix-loop-helix DNA-binding domainoverlaps 67-131