ModCRE DB

Transcription factor

Q86UP3 - ZFHX4

Zinc finger homeobox protein 4 (Zinc finger homeodomain protein 4) (ZFH-4)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 3567 aa

24 Generated PWM 16 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)8
MotifPredictionSourceDNA bindingSupportLogoActions
M02108_2.00 NN 70-40% CisBP CCTAATTAG 56.4% identity Open · Scan
M06304_2.00 NN 70-40% CisBP TTAATTA 56.1% identity Open · Scan
M02182_2.00 NN 70-40% CisBP TTAATTAGC 52.6% identity Open · Scan
M01849_2.00 NN 70-40% CisBP ACTAATTAG 52.5% identity Open · Scan
M05065_2.00 NN 70-40% CisBP TTAACGAG 50.8% identity Open · Scan
M09137_2.00 NN 70-40% CisBP ATTAATTAATTTT 50.8% identity Open · Scan
MA0135.1 NN 70-40% JASPAR AAATTAATTAATC 50.8% identity Open · Scan
MA0704.1 NN 70-40% JASPAR TTAATTAA 50.8% identity Open · Scan
ModCRE16
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q86UP3_ZFHX4_HUMAN:2181:2234_3d1n_L_1 ModCRE Homology model TTTTAATTTAACTA Region 2181-2234 · 1 3D model Open · Scan
DIMER_sp_Q86UP3_ZFHX4_HUMAN:2533:2617_3l1p_B_1 ModCRE Homology model CTAAAAAAAATTTTTTTTTAGG Region 2533-2617 · 1 3D model Open · Scan
DIMER_sp_Q86UP3_ZFHX4_HUMAN:2561:2614_6a8r_B_1 ModCRE Homology model CAATGTCTGA Region 2561-2614 · 1 3D model Open · Scan
DIMER_sp_Q86UP3_ZFHX4_HUMAN:2561:2617_5hod_A_1 ModCRE Homology model TCAATTAGGGGTCATGAG Region 2561-2617 · 1 3D model Open · Scan
DIMER_sp_Q86UP3_ZFHX4_HUMAN:2885:2941_3a01_B_1 ModCRE Homology model TTTTAATTAATTAGGGG Region 2885-2941 · 1 3D model Open · Scan
DIMER_sp_Q86UP3_ZFHX4_HUMAN:2886:2941_1hdd_D_1 ModCRE Homology model GGCCCTTTATTGGCTCA Region 2886-2941 · 1 3D model Open · Scan
DIMER_sp_Q86UP3_ZFHX4_HUMAN:2886:2941_3hdd_B_1 ModCRE Homology model CGGCCTTAATTGGCTCA Region 2886-2941 · 1 3D model Open · Scan
TFS_sp_Q86UP3_ZFHX4_HUMAN:2180:2241_2lkx_A_1 ModCRE Homology model CCCATGATGGATT Region 2180-2241 · 1 3D model Open · Scan
TFS_sp_Q86UP3_ZFHX4_HUMAN:2180:2245_1puf_A_1 ModCRE Homology model CCCCCATAAATTGAAAA Region 2180-2245 · 1 3D model Open · Scan
TFS_sp_Q86UP3_ZFHX4_HUMAN:2182:2238_3a01_B_1 ModCRE Homology model CCCCTAATGACAAAGGG Region 2182-2238 · 1 3D model Open · Scan
TFS_sp_Q86UP3_ZFHX4_HUMAN:2185:2238_3lnq_A_1 ModCRE Homology model AACATTAATTAAAA Region 2185-2238 · 1 3D model Open · Scan
TFS_sp_Q86UP3_ZFHX4_HUMAN:2186:2238_4rbo_A_1 ModCRE Homology model TTCTCATTAGGG Region 2186-2238 · 1 3D model Open · Scan
TFS_sp_Q86UP3_ZFHX4_HUMAN:2533:2617_3l1p_B_1 ModCRE Homology model CCTTAAAAAAAATTTTTTTTAG Region 2533-2617 · 1 3D model Open · Scan
TFS_sp_Q86UP3_ZFHX4_HUMAN:2561:2617_5hod_A_1 ModCRE Homology model CTCATTACCTCTAATTGA Region 2561-2617 · 1 3D model Open · Scan
TFS_sp_Q86UP3_ZFHX4_HUMAN:2885:2941_3a01_B_1 ModCRE Homology model TTCTAATTAATTAGGGG Region 2885-2941 · 1 3D model Open · Scan
TFS_sp_Q86UP3_ZFHX4_HUMAN:2886:2941_3lnq_A_1 ModCRE Homology model TATATTAATTGTTC Region 2886-2941 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 3567 aa
2173-2941

Region 2173-2941 16 PWM

Residues
769 aa
Domains
PF00046 · Homeodomain PF00046 · Homeodomain PF00046 · Homeodomain
3D models
16 active PDBs · 10 summary rows
Templates
1HDD, 1PUF, 2LKX, 3A01, 3D1N, 3HDD, 3L1P, 3LNQ, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
16 active PDB models 10 summary rows
Region 2173-294116 models · 10 summary rows
Actions
Predicted = Low DIMER_sp_Q86UP3_ZFHX4_HUMAN:2181:2234_3d1n_L_1 3d1n 2181-2234 View model · PDB
Predicted = Low DIMER_sp_Q86UP3_ZFHX4_HUMAN:2533:2617_3l1p_B_1 3l1p 2533-2617 View model · PDB
Predicted = Low DIMER_sp_Q86UP3_ZFHX4_HUMAN:2561:2614_6a8r_B_1 6a8r 2561-2614 View model · PDB
Predicted = Low DIMER_sp_Q86UP3_ZFHX4_HUMAN:2561:2617_5hod_A_1 5hod 2561-2617 View model · PDB
Predicted = Low DIMER_sp_Q86UP3_ZFHX4_HUMAN:2885:2941_3a01_B_1 3a01 2885-2941 View model · PDB
Predicted = Low DIMER_sp_Q86UP3_ZFHX4_HUMAN:2886:2941_1hdd_D_1 1hdd 2886-2941 View model · PDB
Predicted = Low DIMER_sp_Q86UP3_ZFHX4_HUMAN:2886:2941_3hdd_B_1 3hdd 2886-2941 View model · PDB
Predicted = Low TFS_sp_Q86UP3_ZFHX4_HUMAN:2180:2241_2lkx_A_1 2lkx 2180-2241 View model · PDB
Predicted = Low TFS_sp_Q86UP3_ZFHX4_HUMAN:2180:2245_1puf_A_1 1puf 2180-2245 View model · PDB
Predicted = Low TFS_sp_Q86UP3_ZFHX4_HUMAN:2182:2238_3a01_B_1 3a01 2182-2238 View model · PDB
Predicted = Low TFS_sp_Q86UP3_ZFHX4_HUMAN:2185:2238_3lnq_A_1 3lnq 2185-2238 View model · PDB
Predicted = Low TFS_sp_Q86UP3_ZFHX4_HUMAN:2186:2238_4rbo_A_1 4rbo 2186-2238 View model · PDB
Predicted = Low TFS_sp_Q86UP3_ZFHX4_HUMAN:2533:2617_3l1p_B_1 3l1p 2533-2617 View model · PDB
Predicted = Low TFS_sp_Q86UP3_ZFHX4_HUMAN:2561:2617_5hod_A_1 5hod 2561-2617 View model · PDB
Predicted = Low TFS_sp_Q86UP3_ZFHX4_HUMAN:2885:2941_3a01_B_1 3a01 2885-2941 View model · PDB
Predicted = Low TFS_sp_Q86UP3_ZFHX4_HUMAN:2886:2941_3lnq_A_1 3lnq 2886-2941 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 5hod 2533:2621 2561,2562 2617,2617 P:A,D · DNA:B,C 50.9% / 64.9% 93,96 View · PDB TFS_sp_Q86UP3_ZFHX4_HUMAN:2561:2617_5hod_A_1
1 5hod 2533:2621 2561,2562 2617,2617 P:A,D · DNA:B,C 50.9% / 64.9% 93,96 View · PIR DIMER_sp_Q86UP3_ZFHX4_HUMAN:2561:2617_5hod_A_1
5 3hdd 2533:2621 2888,2886 2941,2941 P:A,B · DNA:C,D 42.9% / 62.5% 98,100 View · PDB DIMER_sp_Q86UP3_ZFHX4_HUMAN:2886:2941_3hdd_B_1
3 3lnq 2533:2621 2886 2941 P:A · DNA:B,C 42.9% / 60.7% 96 View · PDB TFS_sp_Q86UP3_ZFHX4_HUMAN:2886:2941_3lnq_A_1
2 3a01 2533:2621 2173,2885 2238,2941 P:A,B · DNA:C,D 42.1% / 61.4% 84,100 View · PDB TFS_sp_Q86UP3_ZFHX4_HUMAN:2885:2941_3a01_B_1
2 3a01 2533:2621 2173,2885 2238,2941 P:A,B · DNA:C,D 42.1% / 61.4% 84,100 View · PDB DIMER_sp_Q86UP3_ZFHX4_HUMAN:2885:2941_3a01_B_1
4 2lkx 2533:2621 2180 2241 P:A · DNA:B,C 40.3% / 53.2% 91 View · PDB TFS_sp_Q86UP3_ZFHX4_HUMAN:2180:2241_2lkx_A_1
4 3d1n 2533:2621 2181,2181 2234,2234 P:K,L · DNA:C,D 38.9% / 51.9% 36,37 View · PDB DIMER_sp_Q86UP3_ZFHX4_HUMAN:2181:2234_3d1n_L_1
3 3l1p 2533:2621 2533,2533 2617,2617 P:A,B · DNA:M,N 32.9% / 51.8% 55,55 View · PDB DIMER_sp_Q86UP3_ZFHX4_HUMAN:2533:2617_3l1p_B_1
5 3l1p 2533:2621 2533,2533 2617,2617 P:A,B · DNA:M,N 32.9% / 51.8% 55,55 View · PDB TFS_sp_Q86UP3_ZFHX4_HUMAN:2533:2617_3l1p_B_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
699-723PF12874Zinc-finger of C2H2 typeNo overlap with loaded model regions
973-997PF24056Zinc finger homeobox protein 3-like, C2H2 type zinc-fingerNo overlap with loaded model regions
1548-1572PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
2085-2141PF00046HomeodomainNo overlap with loaded model regions
2182-2238PF00046Homeodomainoverlaps 2173-2941
2561-2617PF00046Homeodomainoverlaps 2173-2941
2885-2941PF00046Homeodomainoverlaps 2173-2941