ModCRE DB

Transcription factor

Q86UQ0 - ZNF589

Zinc finger protein 589 (Stem cell zinc finger protein 1)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 364 aa

63 Generated PWM 6 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)58
MotifPredictionSourceDNA bindingSupportLogoActions
M08371_2.00 NN 70-40% CisBP CCAGACTTGTCCTCT 59.2% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 58.9% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 58.9% identity Open · Scan
M07646_2.00 NN 70-40% CisBP CTTTTTTTT 57.8% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 57.6% identity Open · Scan
M07605_2.00 NN 70-40% CisBP TATTTTTTTTTATTTTTTTTTTTTTTTTTT 57.3% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 56.7% identity Open · Scan
M07579_2.00 NN 70-40% CisBP CATCTCCAGGA 56.6% identity Open · Scan
M07777_2.00 NN 70-40% CisBP GCCAATTTCCGTGGTGTAAAT 56.6% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 56.4% identity Open · Scan
M07700_2.00 NN 70-40% CisBP ATGTTGTGAGGAAGCCCA 55.6% identity Open · Scan
M07593_2.00 NN 70-40% CisBP AGATGAAGTCACCCCTCTTAC 55.4% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 55.2% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 55.2% identity Open · Scan
M04613_2.00 NN 70-40% CisBP CTCATGTGCTAATTACAAA 55.2% identity Open · Scan
M07725_2.00 NN 70-40% CisBP AAGCACTGTACT 55.1% identity Open · Scan
M04505_2.00 NN 70-40% CisBP AGCTTTTCCCACAC 54.8% identity Open · Scan
M07638_2.00 NN 70-40% CisBP TGCAGCTCCCTGCCC 54.8% identity Open · Scan
M07683_2.00 NN 70-40% CisBP GTGGGAAAGCCT 54.8% identity Open · Scan
M08252_2.00 NN 70-40% CisBP CCGGCTCCAGCACCC 54.8% identity Open · Scan
MA1601.1 NN 70-40% JASPAR ATGTGGGAAA 54.8% identity Open · Scan
M07686_2.00 NN 70-40% CisBP TAGCTTGTTTCCAGCCAC 53.9% identity Open · Scan
M08245_2.00 NN 70-40% CisBP TGGTGCCTTATTCCC 53.1% identity Open · Scan
M08263_2.00 NN 70-40% CisBP ATCTCGGCACTTTGGGAGGCCA 53.1% identity Open · Scan
M04590_2.00 NN 70-40% CisBP TGCGCTAACCATTGC 53.0% identity Open · Scan
M07623_2.00 NN 70-40% CisBP GTCTAATAGAGCTGGGCTGCA 53.0% identity Open · Scan
M08309_2.00 NN 70-40% CisBP AAAAACCCCCCTGCAGAGCCCAGCCCT 53.0% identity Open · Scan
M08335_2.00 NN 70-40% CisBP AGTCGTTGTCTG 53.0% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 52.9% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 52.9% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 52.9% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 52.9% identity Open · Scan
M07754_2.00 NN 70-40% CisBP CGCCCCCTCCCT 52.6% identity Open · Scan
M08279_2.00 NN 70-40% CisBP CCTCCCTCC 52.4% identity Open · Scan
M07581_2.00 NN 70-40% CisBP TCCCCTGTGCTTCTCTCCCCT 52.3% identity Open · Scan
M07723_2.00 NN 70-40% CisBP CCGCTGCTCCCTGCT 52.2% identity Open · Scan
M00774_2.00 NN 70-40% CisBP TTAGTATACACAAGT 51.7% identity Open · Scan
M08314_2.00 NN 70-40% CisBP ATTCATCAAGGTCCTCAACAATGG 51.7% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 51.7% identity Open · Scan
M07601_2.00 NN 70-40% CisBP CAGATGCCGGCACCATGCTTC 51.3% identity Open · Scan
M08274_2.00 NN 70-40% CisBP TTACTTGCAGCCCAACGCATTCCTAAC 51.3% identity Open · Scan
MA1154.1 NN 70-40% JASPAR CTTTCCCACAACACGAC 51.3% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 51.0% identity Open · Scan
M07684_2.00 NN 70-40% CisBP CCTGTTCTTGACTTT 51.0% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 51.0% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 50.9% identity Open · Scan
M04475_2.00 NN 70-40% CisBP GATGCACGTACCGTGCCTCA 50.8% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 50.5% identity Open · Scan
MA1602.1 NN 70-40% JASPAR CGTCTACACGGG 50.4% identity Open · Scan
M08292_2.00 NN 70-40% CisBP TGTATTCCTTGTCATGTGTGG 50.3% identity Open · Scan
M01456_2.00 NN 70-40% CisBP GTGATCGGCG 50.0% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 50.0% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 50.0% identity Open · Scan
M07562_2.00 NN 70-40% CisBP GAAAAAAAC 50.0% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 50.0% identity Open · Scan
M08358_2.00 NN 70-40% CisBP CCCTCCCCCTCC 50.0% identity Open · Scan
M08366_2.00 NN 70-40% CisBP GTTTGCTGCTTACAA 50.0% identity Open · Scan
MA1587.1 NN 70-40% JASPAR CCTCGACCTCCTGA 50.0% identity Open · Scan
ModCRE5
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_sp_Q86UQ0_ZN589_HUMAN:249:355_5egb_A_1 ModCRE Homology model CCCCCCGCAGGAGGGGGT Region 249-355 · 1 3D model Open · Scan
TFS_sp_Q86UQ0_ZN589_HUMAN:249:355_5eh2_F_1 ModCRE Homology model CCCCCCGGGGGGGGGGCCC Region 249-355 · 1 3D model Open · Scan
TFS_sp_Q86UQ0_ZN589_HUMAN:249:355_5ei9_E_1 ModCRE Homology model GCCCCCGGGGGGGGGGGC Region 249-355 · 1 3D model Open · Scan
TFS_sp_Q86UQ0_ZN589_HUMAN:250:362_2i13_A_1 ModCRE Homology model AGCACCGGCCAAAAGCAGTCT Region 250-362 · 1 3D model Open · Scan
TFS_sp_Q86UQ0_ZN589_HUMAN:250:364_5wjq_D_1 ModCRE Homology model GGGGGGGGGGGTGGCCCCCCC Region 250-364 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 364 aa
249-364

Region 249-364 5 PWM

Residues
116 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
6 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5EGB, 5EH2, 5EI9, 5WJQ
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
6 active PDB models 6 summary rows
Region 249-3646 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_Q86UQ0_ZN589_HUMAN:302:353_1llm_C_1 1llm 302-353 View model · PDB
Predicted = Low TFS_sp_Q86UQ0_ZN589_HUMAN:249:355_5egb_A_1 5egb 249-355 View model · PDB
Predicted = Low TFS_sp_Q86UQ0_ZN589_HUMAN:249:355_5eh2_F_1 5eh2 249-355 View model · PDB
Predicted = Low TFS_sp_Q86UQ0_ZN589_HUMAN:249:355_5ei9_E_1 5ei9 249-355 View model · PDB
Predicted = Low TFS_sp_Q86UQ0_ZN589_HUMAN:250:362_2i13_A_1 2i13 250-362 View model · PDB
Predicted = Low TFS_sp_Q86UQ0_ZN589_HUMAN:250:364_5wjq_D_1 5wjq 250-364 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 5ei9 245:364 249 355 P:E · DNA:A,B 68.2% / 75.7% 96 View · PDB TFS_sp_Q86UQ0_ZN589_HUMAN:249:355_5ei9_E_1
2 5egb 245:364 249 355 P:A · DNA:C,D 68.2% / 75.7% 96 View · PDB TFS_sp_Q86UQ0_ZN589_HUMAN:249:355_5egb_A_1
3 5eh2 245:364 249 355 P:F · DNA:C,D 68.2% / 75.7% 98 View · PDB TFS_sp_Q86UQ0_ZN589_HUMAN:249:355_5eh2_F_1
4 2i13 245:364 250 362 P:A · DNA:C,D 55.8% / 64.6% 74 View · PDB TFS_sp_Q86UQ0_ZN589_HUMAN:250:362_2i13_A_1
5 5wjq 245:364 250 364 P:D · DNA:A,B 48.7% / 68.7% 41 View · PDB TFS_sp_Q86UQ0_ZN589_HUMAN:250:364_5wjq_D_1
1 1llm 245:364 302,302 353,353 P:C,D · DNA:A,B 46.2% / 55.8% 59,61 View · PDB DIMER_sp_Q86UQ0_ZN589_HUMAN:302:353_1llm_C_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
34-74PF01352KRAB boxNo overlap with loaded model regions
81-101PF21225C2H2-type zinc fingerNo overlap with loaded model regions
249-270PF00096Zinc finger, C2H2 typeoverlaps 249-364
276-298PF00096Zinc finger, C2H2 typeoverlaps 249-364
304-326PF00096Zinc finger, C2H2 typeoverlaps 249-364
332-354PF00096Zinc finger, C2H2 typeoverlaps 249-364