ModCRE DB

Transcription factor

Q86WZ6 - ZNF227

Zinc finger protein 227

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 799 aa

115 Generated PWM 6 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)109
MotifPredictionSourceDNA bindingSupportLogoActions
M00960_2.00 NN 70-40% CisBP TGCATCCC 68.2% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 67.0% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 67.0% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 67.0% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 65.8% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 65.4% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 64.7% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 64.7% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 64.7% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 62.3% identity Open · Scan
M08314_2.00 NN 70-40% CisBP ATTCATCAAGGTCCTCAACAATGG 62.0% identity Open · Scan
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 61.1% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 61.0% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 60.6% identity Open · Scan
M08985_2.00 NN 70-40% CisBP TGAGGACCTACTGTGTGCC 59.8% identity Open · Scan
M07613_2.00 NN 70-40% CisBP TCACTCAGTCATTCA 59.7% identity Open · Scan
M04613_2.00 NN 70-40% CisBP CTCATGTGCTAATTACAAA 59.4% identity Open · Scan
M08375_2.00 NN 70-40% CisBP TTCCCCATTGGCTACTGCACCGGTCCT 59.4% identity Open · Scan
M07610_2.00 NN 70-40% CisBP CCTTCTTCCTCCCCCCTGCCCACC 58.6% identity Open · Scan
M08252_2.00 NN 70-40% CisBP CCGGCTCCAGCACCC 58.2% identity Open · Scan
M08934_2.00 NN 70-40% CisBP GCTGTACCTGCTTATTAGGC 57.9% identity Open · Scan
M08901_2.00 NN 70-40% CisBP CCAGTTCACACC 57.8% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 57.8% identity Open · Scan
M07590_2.00 NN 70-40% CisBP TTTTTTTCTTTTATTTTTTTTTTTTTTTTTTTT 57.7% identity Open · Scan
M08887_2.00 NN 70-40% CisBP CCTCCTCCAGGAAGCCTTCCCTGA 57.6% identity Open · Scan
MA1587.1 NN 70-40% JASPAR CCTCGACCTCCTGA 57.4% identity Open · Scan
M04505_2.00 NN 70-40% CisBP AGCTTTTCCCACAC 57.2% identity Open · Scan
M07687_2.00 NN 70-40% CisBP ACAAATAAGGTTCTTGTGCCCCCTGCT 56.9% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 56.7% identity Open · Scan
M01456_2.00 NN 70-40% CisBP GTGATCGGCG 56.5% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 56.5% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 56.3% identity Open · Scan
M07700_2.00 NN 70-40% CisBP ATGTTGTGAGGAAGCCCA 56.2% identity Open · Scan
M08944_2.00 NN 70-40% CisBP TACCATGCTGTTTTGATTAC 56.2% identity Open · Scan
M07764_2.00 NN 70-40% CisBP CTGCACTCTCCCCTTCCCCCCCTCCCC 56.1% identity Open · Scan
M07635_2.00 NN 70-40% CisBP AAGTTTTCTTGTATTATATCT 56.0% identity Open · Scan
M07689_2.00 NN 70-40% CisBP ACCCAGGCTCCTTCCATCTTGTGGCTC 56.0% identity Open · Scan
M07649_2.00 NN 70-40% CisBP CCCCCCCCCCCCTCAGGAATGCC 55.9% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 55.8% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 55.7% identity Open · Scan
M07667_2.00 NN 70-40% CisBP CCGCACAGGCCCCCGGGCCCC 55.7% identity Open · Scan
M08373_2.00 NN 70-40% CisBP CCCCCTGGCTCTTCCTCT 55.5% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 55.4% identity Open · Scan
M07657_2.00 NN 70-40% CisBP CCCCTGCATGTCCCCATTTTT 55.1% identity Open · Scan
M07701_2.00 NN 70-40% CisBP CCTGGGCTAGGCCCTGGC 55.0% identity Open · Scan
M07605_2.00 NN 70-40% CisBP TATTTTTTTTTATTTTTTTTTTTTTTTTTT 54.9% identity Open · Scan
M00645_2.00 NN 70-40% CisBP CGCCCACGCA 54.8% identity Open · Scan
M07562_2.00 NN 70-40% CisBP GAAAAAAAC 54.8% identity Open · Scan
M08347_2.00 NN 70-40% CisBP GCCCTGGGCAGC 54.8% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 54.7% identity Open · Scan
M07761_2.00 NN 70-40% CisBP CTGATTATTCACCCA 54.4% identity Open · Scan
M08311_2.00 NN 70-40% CisBP CTGGAACAGAAGGGGCGA 54.4% identity Open · Scan
M07715_2.00 NN 70-40% CisBP CCGCCGCCGCCGTGG 54.2% identity Open · Scan
M07565_2.00 NN 70-40% CisBP CCTCTGGGGGCTCGTCCA 54.0% identity Open · Scan
M07618_2.00 NN 70-40% CisBP CCTTTGGTGCTC 54.0% identity Open · Scan
M07666_2.00 NN 70-40% CisBP ATCTAGCCCCTGCCTACC 53.9% identity Open · Scan
M07586_2.00 NN 70-40% CisBP GGGACCCGGGTGGGGGCGTCCCCC 53.8% identity Open · Scan
M08330_2.00 NN 70-40% CisBP TGGGTGCCGGACTGCTGTTCC 53.8% identity Open · Scan
M07579_2.00 NN 70-40% CisBP CATCTCCAGGA 53.5% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 53.4% identity Open · Scan
M03671_2.00 NN 70-40% CisBP ATTACCATACAAGTGCAC 53.3% identity Open · Scan
MA1597.1 NN 70-40% JASPAR CCCAGGGAAGCCATTTC 53.3% identity Open · Scan
MA1599.1 NN 70-40% JASPAR CGGGCCAAGCCCCTAT 53.0% identity Open · Scan
M02896_2.00 NN 70-40% CisBP TGCTTTCTAGGAATTCA 52.9% identity Open · Scan
M08274_2.00 NN 70-40% CisBP TTACTTGCAGCCCAACGCATTCCTAAC 52.9% identity Open · Scan
M08395_2.00 NN 70-40% CisBP GCTGCCTACTCTTCC 52.9% identity Open · Scan
MA0731.1 NN 70-40% JASPAR TGCTTTCTAGGAATTCA 52.9% identity Open · Scan
MA1602.1 NN 70-40% JASPAR CGTCTACACGGG 52.8% identity Open · Scan
M07658_2.00 NN 70-40% CisBP CCGCCGCAGCCGCCG 52.7% identity Open · Scan
M08949_2.00 NN 70-40% CisBP TTCTATTTCTTCTTGTGTCA 52.7% identity Open · Scan
M01474_2.00 NN 70-40% CisBP CGCCGATCAC 52.6% identity Open · Scan
M08334_2.00 NN 70-40% CisBP TTTGTTTTTTTCTGATTGCTTTTTACTTAT 52.6% identity Open · Scan
M07767_2.00 NN 70-40% CisBP AAAAACCCCAGA 52.4% identity Open · Scan
M08381_2.00 NN 70-40% CisBP ACATTTTGTCCTCCTAGTCCT 52.4% identity Open · Scan
M07753_2.00 NN 70-40% CisBP TGCATTCCTTGGCTTGTG 52.3% identity Open · Scan
M07775_2.00 NN 70-40% CisBP GCCGAAACCCGGG 52.3% identity Open · Scan
M08908_2.00 NN 70-40% CisBP GCTGCTGCTTCTGCTG 52.3% identity Open · Scan
M07685_2.00 NN 70-40% CisBP CTTTCCAGCCAC 52.2% identity Open · Scan
M07646_2.00 NN 70-40% CisBP CTTTTTTTT 52.1% identity Open · Scan
M07754_2.00 NN 70-40% CisBP CGCCCCCTCCCT 52.1% identity Open · Scan
M07683_2.00 NN 70-40% CisBP GTGGGAAAGCCT 52.0% identity Open · Scan
MA1601.1 NN 70-40% JASPAR ATGTGGGAAA 52.0% identity Open · Scan
M02731_2.00 NN 70-40% CisBP CACTTTCACTTT 51.9% identity Open · Scan
M07566_2.00 NN 70-40% CisBP TCAAACCATCCTTGC 51.9% identity Open · Scan
M08309_2.00 NN 70-40% CisBP AAAAACCCCCCTGCAGAGCCCAGCCCT 51.9% identity Open · Scan
MA0508.1 NN 70-40% JASPAR AGAAAGTGAAAGTGA 51.9% identity Open · Scan
M07723_2.00 NN 70-40% CisBP CCGCTGCTCCCTGCT 51.8% identity Open · Scan
M08921_2.00 NN 70-40% CisBP CCTCATTCTTCTTGGACATG 51.8% identity Open · Scan
M04621_2.00 NN 70-40% CisBP AGCAATTCCGCTCA 51.6% identity Open · Scan
MA1589.1 NN 70-40% JASPAR TAGGAGTGGAATTGCTGGGTC 51.6% identity Open · Scan
M00764_2.00 NN 70-40% CisBP GTCTACAC 51.5% identity Open · Scan
M07714_2.00 NN 70-40% CisBP AGCCCATTGGGGCCTATGCCC 51.5% identity Open · Scan
M05853_2.00 NN 70-40% CisBP CCACCTTTAGCCATATCT 51.4% identity Open · Scan
M00609_2.00 NN 70-40% CisBP GGAAGCCCTA 51.3% identity Open · Scan
M07620_2.00 NN 70-40% CisBP TTGGATCTGTGGATTCATGTCTTTCAT 51.3% identity Open · Scan
M08254_2.00 NN 70-40% CisBP CTGCCCTGGGACTTT 51.3% identity Open · Scan
M07699_2.00 NN 70-40% CisBP GGTTTAT 51.1% identity Open · Scan
M04536_2.00 NN 70-40% CisBP ACGTAACCCGATACC 51.0% identity Open · Scan
M04465_2.00 NN 70-40% CisBP GTGATTCTTATCTTATCCTT 50.7% identity Open · Scan
M08357_2.00 NN 70-40% CisBP GAGCCTGCTACTGAGCCTGGG 50.7% identity Open · Scan
M08860_2.00 NN 70-40% CisBP TCTTATAAGGGCACTAATCCCATT 50.7% identity Open · Scan
M00142_2.00 NN 70-40% CisBP GTGCTCCT 50.5% identity Open · Scan
M00786_2.00 NN 70-40% CisBP TATATATAT 50.5% identity Open · Scan
M07628_2.00 NN 70-40% CisBP AGTGGTTCTGCTTCT 50.3% identity Open · Scan
M07648_2.00 NN 70-40% CisBP GCTTGCAAAAAAAATTTAACTCCCAGCTC 50.3% identity Open · Scan
M07729_2.00 NN 70-40% CisBP CCAGACTGCCTGCCAAAACCCCCT 50.3% identity Open · Scan
M08255_2.00 NN 70-40% CisBP CTCTTCCGGT 50.2% identity Open · Scan
M07600_2.00 NN 70-40% CisBP GCATTAGC 50.0% identity Open · Scan
MA0528.1 NN 70-40% JASPAR GGAGGAGGAGGGGGAGGAGGA 50.0% identity Open · Scan
ModCRE6
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q86WZ6_ZN227_HUMAN:518:569_1llm_D_1 ModCRE Homology model GTTCGGACGCTA Region 518-569 · 1 3D model Open · Scan
TFS_sp_Q86WZ6_ZN227_HUMAN:333:486_2i13_A_1 ModCRE Homology model GTGAAGTTGAAGGCTTTTGAT Region 333-486 · 1 3D model Open · Scan
TFS_sp_Q86WZ6_ZN227_HUMAN:377:655_5wjq_D_1 ModCRE Homology model TGGATACCCCCCCACCCTCGCCCCCCAA Region 377-655 · 1 3D model Open · Scan
TFS_sp_Q86WZ6_ZN227_HUMAN:435:711_5v3j_E_1 ModCRE Homology model CTCCAGGGTTTTGCCCCACCCGGGAA Region 435-711 · 1 3D model Open · Scan
TFS_sp_Q86WZ6_ZN227_HUMAN:435:711_5v3m_C_1 ModCRE Homology model CGGACCCGTCTTCCCCCCCCCCCCGA Region 435-711 · 1 3D model Open · Scan
TFS_sp_Q86WZ6_ZN227_HUMAN:436:734_7w1m_H_1 ModCRE Homology model TTTTCGCCAATTTTGGAATCGTGTCCTTCGGGTTCGGGGCCTA Region 436-734 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 799 aa
333-734

Region 333-734 6 PWM

Residues
402 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
6 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
6 active PDB models 6 summary rows
Region 333-7346 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_Q86WZ6_ZN227_HUMAN:518:569_1llm_D_1 1llm 518-569 View model · PDB
Predicted = Low TFS_sp_Q86WZ6_ZN227_HUMAN:333:486_2i13_A_1 2i13 333-486 View model · PDB
Predicted = Low TFS_sp_Q86WZ6_ZN227_HUMAN:377:655_5wjq_D_1 5wjq 377-655 View model · PDB
Predicted = Low TFS_sp_Q86WZ6_ZN227_HUMAN:435:711_5v3j_E_1 5v3j 435-711 View model · PDB
Predicted = Low TFS_sp_Q86WZ6_ZN227_HUMAN:435:711_5v3m_C_1 5v3m 435-711 View model · PDB
Predicted = Low TFS_sp_Q86WZ6_ZN227_HUMAN:436:734_7w1m_H_1 7w1m 436-734 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 2i13 321:734 333 486 P:A · DNA:C,D 61.0% / 64.9% 100 View · PDB TFS_sp_Q86WZ6_ZN227_HUMAN:333:486_2i13_A_1
1 5wjq 321:734 377 655 P:D · DNA:A,B 52.3% / 70.3% 99 View · PDB TFS_sp_Q86WZ6_ZN227_HUMAN:377:655_5wjq_D_1
2 5v3m 321:734 435 711 P:C · DNA:A,B 52.3% / 68.2% 100 View · PDB TFS_sp_Q86WZ6_ZN227_HUMAN:435:711_5v3m_C_1
3 5v3j 321:734 435 711 P:E · DNA:A,B 52.3% / 68.2% 100 View · PDB TFS_sp_Q86WZ6_ZN227_HUMAN:435:711_5v3j_E_1
1 1llm 321:734 518,518 569,569 P:C,D · DNA:A,B 50.0% / 65.4% 59,61 View · PDB DIMER_sp_Q86WZ6_ZN227_HUMAN:518:569_1llm_D_1
5 7w1m 321:734 436 734 P:H · DNA:F,G 35.1% / 48.1% 92 View · PDB TFS_sp_Q86WZ6_ZN227_HUMAN:436:734_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
23-63PF01352KRAB boxNo overlap with loaded model regions
324-346PF00096Zinc finger, C2H2 typeoverlaps 333-734
352-374PF00096Zinc finger, C2H2 typeoverlaps 333-734
380-402PF00096Zinc finger, C2H2 typeoverlaps 333-734
408-430PF00096Zinc finger, C2H2 typeoverlaps 333-734
436-458PF00096Zinc finger, C2H2 typeoverlaps 333-734
464-486PF00096Zinc finger, C2H2 typeoverlaps 333-734
492-514PF00096Zinc finger, C2H2 typeoverlaps 333-734
520-542PF00096Zinc finger, C2H2 typeoverlaps 333-734
548-570PF00096Zinc finger, C2H2 typeoverlaps 333-734
576-598PF00096Zinc finger, C2H2 typeoverlaps 333-734
604-626PF00096Zinc finger, C2H2 typeoverlaps 333-734
632-654PF00096Zinc finger, C2H2 typeoverlaps 333-734
660-682PF00096Zinc finger, C2H2 typeoverlaps 333-734
688-710PF00096Zinc finger, C2H2 typeoverlaps 333-734
716-738PF00096Zinc finger, C2H2 typeoverlaps 333-734
744-766PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
772-794PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions