ModCRE DB

Transcription factor

Q86XU0 - ZNF677

Zinc finger protein 677

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 584 aa

70 Generated PWM 7 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known2
MotifPredictionSourceDNA bindingSupportLogoActions
MA2101.1 Known JASPAR GATAAGAACAGC Direct PWM Open · Scan
M08382_2.00 Known CisBP AGGCTGTTCTTGTCGGGGTCC Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)67
MotifPredictionSourceDNA bindingSupportLogoActions
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 68.2% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 65.0% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 64.8% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 63.9% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 63.9% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 63.5% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 62.7% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 62.7% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 62.6% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 62.3% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 62.3% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 61.6% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 60.8% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 59.6% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 59.3% identity Open · Scan
M08375_2.00 NN 70-40% CisBP TTCCCCATTGGCTACTGCACCGGTCCT 59.2% identity Open · Scan
M04613_2.00 NN 70-40% CisBP CTCATGTGCTAATTACAAA 58.9% identity Open · Scan
M08985_2.00 NN 70-40% CisBP TGAGGACCTACTGTGTGCC 58.9% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 58.7% identity Open · Scan
M00945_2.00 NN 70-40% CisBP CACCGCAC 58.6% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 58.2% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 58.2% identity Open · Scan
M08334_2.00 NN 70-40% CisBP TTTGTTTTTTTCTGATTGCTTTTTACTTAT 57.7% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 57.5% identity Open · Scan
M07562_2.00 NN 70-40% CisBP GAAAAAAAC 57.1% identity Open · Scan
M00609_2.00 NN 70-40% CisBP GGAAGCCCTA 56.8% identity Open · Scan
M07578_2.00 NN 70-40% CisBP CAACTCTCC 56.5% identity Open · Scan
M08901_2.00 NN 70-40% CisBP CCAGTTCACACC 55.7% identity Open · Scan
M07660_2.00 NN 70-40% CisBP CCGCGCCTACCTGAGGGCGCGGGCCTGGGG 55.6% identity Open · Scan
M08292_2.00 NN 70-40% CisBP TGTATTCCTTGTCATGTGTGG 55.6% identity Open · Scan
M07702_2.00 NN 70-40% CisBP CTTCTTCCTTGG 55.5% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 55.1% identity Open · Scan
M08392_2.00 NN 70-40% CisBP CTTCACCTGCTGAGG 55.1% identity Open · Scan
M08860_2.00 NN 70-40% CisBP TCTTATAAGGGCACTAATCCCATT 55.0% identity Open · Scan
M07566_2.00 NN 70-40% CisBP TCAAACCATCCTTGC 54.8% identity Open · Scan
M07649_2.00 NN 70-40% CisBP CCCCCCCCCCCCTCAGGAATGCC 54.4% identity Open · Scan
M08283_2.00 NN 70-40% CisBP GACTTTTATTTT 54.1% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 54.0% identity Open · Scan
M04621_2.00 NN 70-40% CisBP AGCAATTCCGCTCA 53.5% identity Open · Scan
M07656_2.00 NN 70-40% CisBP TGTCTAGTAAGTCTA 53.4% identity Open · Scan
M07587_2.00 NN 70-40% CisBP CCCCCTCCCCAGTCGAGCCCCCGC 53.1% identity Open · Scan
M08247_2.00 NN 70-40% CisBP AAAAATAACAAACGG 53.0% identity Open · Scan
M08342_2.00 NN 70-40% CisBP GCTCTGCCTCCCTCT 52.8% identity Open · Scan
M08908_2.00 NN 70-40% CisBP GCTGCTGCTTCTGCTG 52.7% identity Open · Scan
MA1656.1 NN 70-40% JASPAR CCAAGCCCAACCAG 52.7% identity Open · Scan
M07600_2.00 NN 70-40% CisBP GCATTAGC 52.5% identity Open · Scan
M07746_2.00 NN 70-40% CisBP CAGCTGGCGCCCAACATGGGTCCC 52.5% identity Open · Scan
M00134_2.00 NN 70-40% CisBP GCCACGCCCA 52.4% identity Open · Scan
M07683_2.00 NN 70-40% CisBP GTGGGAAAGCCT 52.3% identity Open · Scan
MA1601.1 NN 70-40% JASPAR ATGTGGGAAA 52.3% identity Open · Scan
MA1600.1 NN 70-40% JASPAR ATACAGTCCACCCCTTTA 52.1% identity Open · Scan
M08373_2.00 NN 70-40% CisBP CCCCCTGGCTCTTCCTCT 51.8% identity Open · Scan
M04590_2.00 NN 70-40% CisBP TGCGCTAACCATTGC 51.7% identity Open · Scan
M07717_2.00 NN 70-40% CisBP GGCTCCGCCCCC 51.7% identity Open · Scan
M08335_2.00 NN 70-40% CisBP AGTCGTTGTCTG 51.1% identity Open · Scan
M01044_2.00 NN 70-40% CisBP TCTCTCTTTC 50.9% identity Open · Scan
M01457_2.00 NN 70-40% CisBP GCGCACGGAC 50.9% identity Open · Scan
M00149_2.00 NN 70-40% CisBP CGTACGCC 50.8% identity Open · Scan
M07648_2.00 NN 70-40% CisBP GCTTGCAAAAAAAATTTAACTCCCAGCTC 50.8% identity Open · Scan
M00786_2.00 NN 70-40% CisBP TATATATAT 50.5% identity Open · Scan
M04536_2.00 NN 70-40% CisBP ACGTAACCCGATACC 50.5% identity Open · Scan
M08366_2.00 NN 70-40% CisBP GTTTGCTGCTTACAA 50.5% identity Open · Scan
MA0528.1 NN 70-40% JASPAR GGAGGAGGAGGGGGAGGAGGA 50.3% identity Open · Scan
MA1154.1 NN 70-40% JASPAR CTTTCCCACAACACGAC 50.3% identity Open · Scan
M07605_2.00 NN 70-40% CisBP TATTTTTTTTTATTTTTTTTTTTTTTTTTT 50.2% identity Open · Scan
M08395_2.00 NN 70-40% CisBP GCTGCCTACTCTTCC 50.2% identity Open · Scan
M08540_2.00 NN 70-40% CisBP CCCCT 50.0% identity Open · Scan
ModCRE1
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_sp_Q86XU0_ZN677_HUMAN:372:482_5ei9_E_1 ModCRE Homology model GGGTGGGCGGGGGCCGG Region 372-482 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 584 aa
255-537

Region 255-537 1 PWM

Residues
283 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
7 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
7 active PDB models 6 summary rows
Region 255-5377 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_Q86XU0_ZN677_HUMAN:373:424_1llm_D_1 1llm 373-424 View model · PDB
Predicted = Low TFS_sp_Q86XU0_ZN677_HUMAN:255:533_7w1m_H_1 7w1m 255-533 View model · PDB
Predicted = Low TFS_sp_Q86XU0_ZN677_HUMAN:260:537_5wjq_D_1 5wjq 260-537 View model · PDB
Predicted = Low TFS_sp_Q86XU0_ZN677_HUMAN:263:537_5v3j_E_1 5v3j 263-537 View model · PDB
Predicted = Low TFS_sp_Q86XU0_ZN677_HUMAN:263:537_5v3m_C_1 5v3m 263-537 View model · PDB
Predicted = Low TFS_sp_Q86XU0_ZN677_HUMAN:272:425_2i13_A_1 2i13 272-425 View model · PDB
Predicted = Low TFS_sp_Q86XU0_ZN677_HUMAN:372:482_5ei9_E_1 5ei9 372-482 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 2i13 255:541 272 425 P:A · DNA:C,D 59.7% / 71.4% 100 View · PDB TFS_sp_Q86XU0_ZN677_HUMAN:272:425_2i13_A_1
2 5v3m 255:541 263 537 P:C · DNA:A,B 53.1% / 70.2% 99 View · PDB TFS_sp_Q86XU0_ZN677_HUMAN:263:537_5v3m_C_1
3 5v3j 255:541 263 537 P:E · DNA:A,B 53.1% / 70.2% 99 View · PDB TFS_sp_Q86XU0_ZN677_HUMAN:263:537_5v3j_E_1
1 5wjq 255:541 260 537 P:D · DNA:A,B 51.4% / 71.6% 98 View · PDB TFS_sp_Q86XU0_ZN677_HUMAN:260:537_5wjq_D_1
1 1llm 255:541 373,373 424,424 P:C,D · DNA:A,B 42.3% / 61.5% 59,61 View · PDB DIMER_sp_Q86XU0_ZN677_HUMAN:373:424_1llm_D_1
5 7w1m 255:541 255 533 P:H · DNA:F,G 36.8% / 53.8% 86 View · PDB TFS_sp_Q86XU0_ZN677_HUMAN:255:533_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
8-48PF01352KRAB boxNo overlap with loaded model regions
263-285PF00096Zinc finger, C2H2 typeoverlaps 255-537
291-313PF00096Zinc finger, C2H2 typeoverlaps 255-537
319-341PF00096Zinc finger, C2H2 typeoverlaps 255-537
347-369PF00096Zinc finger, C2H2 typeoverlaps 255-537
375-397PF00096Zinc finger, C2H2 typeoverlaps 255-537
403-425PF00096Zinc finger, C2H2 typeoverlaps 255-537
431-453PF00096Zinc finger, C2H2 typeoverlaps 255-537
459-481PF00096Zinc finger, C2H2 typeoverlaps 255-537
487-509PF00096Zinc finger, C2H2 typeoverlaps 255-537
515-537PF00096Zinc finger, C2H2 typeoverlaps 255-537