ModCRE DB

Transcription factor

Q8IUM7 - NPAS4

Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (Class E basic helix-loop-helix protein 79) (bHLHe79) (HLH-PAS transcription factor NXF) (PAS domain-containing protein 10)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 802 aa

10 Generated PWM 14 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE10
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q8IUM7_NPAS4_HUMAN:10:46_4h10_A_1 ModCRE Homology model GTCCACAGTGAGTT Region 10-46 · 1 3D model Open · Scan
DIMER_sp_Q8IUM7_NPAS4_HUMAN:3:197_7xhv_B_1 ModCRE Homology model GTGTTTCGCGCGCC Region 3-197 · 1 3D model Open · Scan
DIMER_sp_Q8IUM7_NPAS4_HUMAN:4:333_7xi4_B_1 ModCRE Homology model GTCATACGTGCC Region 4-333 · 1 3D model Open · Scan
DIMER_sp_Q8IUM7_NPAS4_HUMAN:5:294_4zpk_B_1 ModCRE Homology model ACGCACACTCGTGCG Region 5-294 · 1 3D model Open · Scan
DIMER_sp_Q8IUM7_NPAS4_HUMAN:5:294_4zpr_B_1 ModCRE Homology model GGGCGCACACGCGCGCG Region 5-294 · 1 3D model Open · Scan
DIMER_sp_Q8IUM7_NPAS4_HUMAN:69:135_5nj8_A_1 ModCRE Homology model AAACACAGCCAA Region 69-135 · 1 3D model Open · Scan
TFS_sp_Q8IUM7_NPAS4_HUMAN:3:333_7xi3_B_1 ModCRE Homology model TTTGGAGTTAA Region 3-333 · 1 3D model Open · Scan
TFS_sp_Q8IUM7_NPAS4_HUMAN:69:135_5nj8_A_1 ModCRE Homology model AAACATGAT Region 69-135 · 1 3D model Open · Scan
TFS_sp_Q8IUM7_NPAS4_HUMAN:72:135_5v0l_B_1 ModCRE Homology model GGATTTTTTTC Region 72-135 · 1 3D model Open · Scan
TFS_sp_Q8IUM7_NPAS4_HUMAN:77:135_5sy7_B_1 ModCRE Homology model GGGGGCGCCCGCGC Region 77-135 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 802 aa
3-333

Region 3-333 10 PWM

Residues
331 aa
Domains
PF23183 · NPAS4 bHLH domain PF08447 · PAS fold
3D models
14 active PDBs · 10 summary rows
Templates
4H10, 4ZPK, 4ZPR, 5NJ8, 5SY7, 5V0L, 7XHV, 7XI3, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
14 active PDB models 10 summary rows
Region 3-33314 models · 10 summary rows
Actions
Predicted = Low DIMER_sp_Q8IUM7_NPAS4_HUMAN:10:46_4h10_A_1 4h10 10-46 View model · PDB
Predicted = Low DIMER_sp_Q8IUM7_NPAS4_HUMAN:3:197_7xhv_B_1 7xhv 3-197 View model · PDB
Predicted = Low DIMER_sp_Q8IUM7_NPAS4_HUMAN:4:333_7xi4_B_1 7xi4 4-333 View model · PDB
Predicted = Low DIMER_sp_Q8IUM7_NPAS4_HUMAN:5:294_4zpk_B_1 4zpk 5-294 View model · PDB
Predicted = Low DIMER_sp_Q8IUM7_NPAS4_HUMAN:5:294_4zpr_B_1 4zpr 5-294 View model · PDB
Predicted = Low DIMER_sp_Q8IUM7_NPAS4_HUMAN:69:135_5nj8_A_1 5nj8 69-135 View model · PDB
Predicted = Low TFS_sp_Q8IUM7_NPAS4_HUMAN:3:197_7xhv_B_1 7xhv 3-197 View model · PDB
Predicted = Low TFS_sp_Q8IUM7_NPAS4_HUMAN:3:333_7xi3_B_1 7xi3 3-333 View model · PDB
Predicted = Low TFS_sp_Q8IUM7_NPAS4_HUMAN:4:333_7xi4_B_1 7xi4 4-333 View model · PDB
Predicted = Low TFS_sp_Q8IUM7_NPAS4_HUMAN:5:294_4zpk_B_1 4zpk 5-294 View model · PDB
Predicted = Low TFS_sp_Q8IUM7_NPAS4_HUMAN:5:294_4zpr_B_1 4zpr 5-294 View model · PDB
Predicted = Low TFS_sp_Q8IUM7_NPAS4_HUMAN:69:135_5nj8_A_1 5nj8 69-135 View model · PDB
Predicted = Low TFS_sp_Q8IUM7_NPAS4_HUMAN:72:135_5v0l_B_1 5v0l 72-135 View model · PDB
Predicted = Low TFS_sp_Q8IUM7_NPAS4_HUMAN:77:135_5sy7_B_1 5sy7 77-135 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
2 7xhv 3:333 10,3 136,197 P:A,B · DNA:C,D 96.9% / 97.4% 63,100 View · PDB DIMER_sp_Q8IUM7_NPAS4_HUMAN:3:197_7xhv_B_1
3 7xhv 3:333 10,3 136,197 P:A,B · DNA:C,D 96.9% / 97.4% 63,100 View · PDB TFS_sp_Q8IUM7_NPAS4_HUMAN:3:197_7xhv_B_1
1 7xi3 3:333 3 333 P:B · DNA:C,D 91.3% / 92.8% 100 View · PDB TFS_sp_Q8IUM7_NPAS4_HUMAN:3:333_7xi3_B_1
1 7xi4 3:333 10,4 136,333 P:A,B · DNA:C,D 89.5% / 90.7% 41,100 View · PDB DIMER_sp_Q8IUM7_NPAS4_HUMAN:4:333_7xi4_B_1
2 7xi4 3:333 10,4 136,333 P:A,B · DNA:C,D 89.5% / 90.7% 41,100 View · PDB TFS_sp_Q8IUM7_NPAS4_HUMAN:4:333_7xi4_B_1
5 5nj8 3:333 69,10 135,136 P:A,B · DNA:E,F 34.3% / 59.7% 36,63 View · PDB DIMER_sp_Q8IUM7_NPAS4_HUMAN:69:135_5nj8_A_1
3 4zpk 3:333 10,5 136,294 P:A,B · DNA:C,D 24.3% / 40.0% 41,83 View · PDB DIMER_sp_Q8IUM7_NPAS4_HUMAN:5:294_4zpk_B_1
4 4zpk 3:333 10,5 136,294 P:A,B · DNA:C,D 24.3% / 40.0% 41,83 View · PDB TFS_sp_Q8IUM7_NPAS4_HUMAN:5:294_4zpk_B_1
4 4zpr 3:333 10,5 136,294 P:A,B · DNA:C,D 22.8% / 38.7% 43,85 View · PDB DIMER_sp_Q8IUM7_NPAS4_HUMAN:5:294_4zpr_B_1
5 4zpr 3:333 10,5 136,294 P:A,B · DNA:C,D 22.8% / 38.7% 43,85 View · PDB TFS_sp_Q8IUM7_NPAS4_HUMAN:5:294_4zpr_B_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
1-53PF23183NPAS4 bHLH domainoverlaps 3-333
229-295PF08447PAS foldoverlaps 3-333