ModCRE DB

Transcription factor

Q8IVH2 - FOXP4

Forkhead box protein P4 (Fork head-related protein-like A)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 680 aa

22 Generated PWM 15 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known1
MotifPredictionSourceDNA bindingSupportLogoActions
MA2117.1 Known JASPAR GTAAACA Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)9
MotifPredictionSourceDNA bindingSupportLogoActions
M08115_2.00 NN 70-40% CisBP AAGTAAACAGAA 64.2% identity Open · Scan
M00793_2.00 NN 70-40% CisBP TGTAAACAA 61.3% identity Open · Scan
MA0481.1 NN 70-40% JASPAR CAAAAGTAAACAAAG 60.8% identity Open · Scan
M09101_2.00 NN 70-40% CisBP AGTAAACAA 57.7% identity Open · Scan
MA0593.1 NN 70-40% JASPAR AAGTAAACAAA 57.6% identity Open · Scan
M01017_2.00 NN 70-40% CisBP AAAAACAA 54.0% identity Open · Scan
M03753_2.00 NN 70-40% CisBP AAACAACAACAA 51.6% identity Open · Scan
M05866_2.00 NN 70-40% CisBP GTAAACAAAT 51.2% identity Open · Scan
M01016_2.00 NN 70-40% CisBP TGGACGCTAA 50.6% identity Open · Scan
ModCRE12
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q8IVH2_FOXP4_HUMAN:466:547_2a07_F_1 ModCRE Homology model TTTTGAAAAAAATTTTGGG Region 466-547 · 1 3D model Open · Scan
DIMER_sp_Q8IVH2_FOXP4_HUMAN:466:547_2a07_K_1 ModCRE Homology model CTATTAAATAAAAAATTCC Region 466-547 · 1 3D model Open · Scan
DIMER_sp_Q8IVH2_FOXP4_HUMAN:466:547_3qrf_G_1 ModCRE Homology model AAAAATTTTTTCATAG Region 466-547 · 1 3D model Open · Scan
DIMER_sp_Q8IVH2_FOXP4_HUMAN:467:529_6ncm_A_1 ModCRE Homology model TTGTTTTTTTTTT Region 467-529 · 1 3D model Open · Scan
DIMER_sp_Q8IVH2_FOXP4_HUMAN:467:546_4wk8_G_1 ModCRE Homology model AAAATTATTTGTTTAAATG Region 467-546 · 1 3D model Open · Scan
TFS_sp_Q8IVH2_FOXP4_HUMAN:466:547_2a07_F_1 ModCRE Homology model CTATAAAAAAAATTTTGGG Region 466-547 · 1 3D model Open · Scan
TFS_sp_Q8IVH2_FOXP4_HUMAN:466:547_2a07_J_1 ModCRE Homology model CTATTAAATAAAAAATTCC Region 466-547 · 1 3D model Open · Scan
TFS_sp_Q8IVH2_FOXP4_HUMAN:466:547_2a07_K_1 ModCRE Homology model CTATTAAATAAAAAATTCC Region 466-547 · 1 3D model Open · Scan
TFS_sp_Q8IVH2_FOXP4_HUMAN:466:547_2as5_F_1 ModCRE Homology model GGGATTTTTTTCATTT Region 466-547 · 1 3D model Open · Scan
TFS_sp_Q8IVH2_FOXP4_HUMAN:466:547_3qrf_G_1 ModCRE Homology model AAAAATTTTTTCATAG Region 466-547 · 1 3D model Open · Scan
TFS_sp_Q8IVH2_FOXP4_HUMAN:469:547_2a07_G_1 ModCRE Homology model CTATGAAAAAAATTTA Region 469-547 · 1 3D model Open · Scan
TFS_sp_Q8IVH2_FOXP4_HUMAN:469:547_2a07_H_1 ModCRE Homology model AAAGGAAACAATTTTT Region 469-547 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 680 aa
466-547

Region 466-547 12 PWM

Residues
82 aa
Domains
PF00250 · Forkhead domain
3D models
15 active PDBs · 10 summary rows
Templates
2A07, 2AS5, 3QRF, 4WK8, 6NCM, 7VOX
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
15 active PDB models 10 summary rows
Region 466-54715 models · 10 summary rows
Actions
Predicted = Low DIMER_sp_Q8IVH2_FOXP4_HUMAN:466:547_2a07_F_1 2a07 466-547 View model · PDB
Predicted = Low DIMER_sp_Q8IVH2_FOXP4_HUMAN:466:547_2a07_J_1 2a07 466-547 View model · PDB
Predicted = Low DIMER_sp_Q8IVH2_FOXP4_HUMAN:466:547_2a07_K_1 2a07 466-547 View model · PDB
Predicted = Low DIMER_sp_Q8IVH2_FOXP4_HUMAN:466:547_3qrf_G_1 3qrf 466-547 View model · PDB
Predicted = Low DIMER_sp_Q8IVH2_FOXP4_HUMAN:467:528_7vox_C_1 7vox 467-528 View model · PDB
Predicted = Low DIMER_sp_Q8IVH2_FOXP4_HUMAN:467:529_6ncm_A_1 6ncm 467-529 View model · PDB
Predicted = Low DIMER_sp_Q8IVH2_FOXP4_HUMAN:467:546_4wk8_G_1 4wk8 467-546 View model · PDB
Predicted = Low DIMER_sp_Q8IVH2_FOXP4_HUMAN:469:547_2a07_G_1 2a07 469-547 View model · PDB
Predicted = Low TFS_sp_Q8IVH2_FOXP4_HUMAN:466:547_2a07_F_1 2a07 466-547 View model · PDB
Predicted = Low TFS_sp_Q8IVH2_FOXP4_HUMAN:466:547_2a07_J_1 2a07 466-547 View model · PDB
Predicted = Low TFS_sp_Q8IVH2_FOXP4_HUMAN:466:547_2a07_K_1 2a07 466-547 View model · PDB
Predicted = Low TFS_sp_Q8IVH2_FOXP4_HUMAN:466:547_2as5_F_1 2as5 466-547 View model · PDB
Predicted = Low TFS_sp_Q8IVH2_FOXP4_HUMAN:466:547_3qrf_G_1 3qrf 466-547 View model · PDB
Predicted = Low TFS_sp_Q8IVH2_FOXP4_HUMAN:469:547_2a07_G_1 2a07 469-547 View model · PDB
Predicted = Low TFS_sp_Q8IVH2_FOXP4_HUMAN:469:547_2a07_H_1 2a07 469-547 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 2a07 453:547 466,466 547,547 P:F,K · DNA:A,B 90.2% / 95.1% 100,98 View · PDB TFS_sp_Q8IVH2_FOXP4_HUMAN:466:547_2a07_F_1
1 2a07 453:547 466,466 547,547 P:F,K · DNA:A,B 90.2% / 95.1% 100,98 View · PDB DIMER_sp_Q8IVH2_FOXP4_HUMAN:466:547_2a07_F_1
2 2as5 453:547 466 547 P:F · DNA:A,B 90.2% / 95.1% 98 View · PDB TFS_sp_Q8IVH2_FOXP4_HUMAN:466:547_2as5_F_1
2 2a07 453:547 466,466 547,547 P:J,K · DNA:A,B 90.2% / 95.1% 98,98 View · PDB DIMER_sp_Q8IVH2_FOXP4_HUMAN:466:547_2a07_J_1
3 2a07 453:547 466,466 547,547 P:J,K · DNA:A,B 90.2% / 95.1% 98,98 View · PDB TFS_sp_Q8IVH2_FOXP4_HUMAN:466:547_2a07_J_1
3 2a07 453:547 469,466 547,547 P:G,K · DNA:A,B 89.9% / 94.9% 100,98 View · PDB DIMER_sp_Q8IVH2_FOXP4_HUMAN:469:547_2a07_G_1
4 2a07 453:547 469 547 P:H · DNA:C,D 89.9% / 94.9% 100 View · PDB TFS_sp_Q8IVH2_FOXP4_HUMAN:469:547_2a07_H_1
5 2a07 453:547 469,466 547,547 P:G,K · DNA:A,B 89.9% / 94.9% 100,98 View · PDB TFS_sp_Q8IVH2_FOXP4_HUMAN:469:547_2a07_G_1
4 4wk8 453:547 467,467 546,546 P:F,G · DNA:A,B 77.5% / 91.2% 100,100 View · PDB DIMER_sp_Q8IVH2_FOXP4_HUMAN:467:546_4wk8_G_1
5 7vox 453:547 467,467 528,528 P:A,C · DNA:D,E 48.4% / 72.6% 72,72 View · PDB DIMER_sp_Q8IVH2_FOXP4_HUMAN:467:528_7vox_C_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
303-371PF16159FOXP coiled-coil domainNo overlap with loaded model regions
467-544PF00250Forkhead domainoverlaps 466-547