ModCRE DB

Transcription factor

Q8IXF0 - NPAS3

Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Basic-helix-loop-helix-PAS protein MOP6) (Class E basic helix-loop-helix protein 12) (bHLHe12) (Member of PAS protein 6) (PAS domain-containing protein 6)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 933 aa

8 Generated PWM 8 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)0

No generated PWM in this category.

ModCRE8
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q8IXF0_NPAS3_HUMAN:154:410_8osl_N_1 ModCRE Homology model GCGCGGGTCCGACGCGA Region 154-410 · 1 3D model Open · Scan
DIMER_sp_Q8IXF0_NPAS3_HUMAN:51:447_4zpk_B_1 ModCRE Homology model GGGCGCGGTGTACGG Region 51-447 · 1 3D model Open · Scan
DIMER_sp_Q8IXF0_NPAS3_HUMAN:52:434_4zpr_B_1 ModCRE Homology model CCCCCGCCGGTACGCGC Region 52-434 · 1 3D model Open · Scan
DIMER_sp_Q8IXF0_NPAS3_HUMAN:52:448_5sy7_B_1 ModCRE Homology model CCCCCGGCGCGTGCGCGT Region 52-448 · 1 3D model Open · Scan
TFS_sp_Q8IXF0_NPAS3_HUMAN:154:410_8osl_N_1 ModCRE Homology model CCGCGTCGGACCATCGC Region 154-410 · 1 3D model Open · Scan
TFS_sp_Q8IXF0_NPAS3_HUMAN:51:447_4zpk_B_1 ModCRE Homology model GGGCGCGGTGTACGG Region 51-447 · 1 3D model Open · Scan
TFS_sp_Q8IXF0_NPAS3_HUMAN:52:434_4zpr_B_1 ModCRE Homology model CCCCCGCCGGTACGCGC Region 52-434 · 1 3D model Open · Scan
TFS_sp_Q8IXF0_NPAS3_HUMAN:52:448_5sy7_B_1 ModCRE Homology model CCCCCGGCGCGTGCGCGT Region 52-448 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 933 aa
51-448

Region 51-448 8 PWM

Residues
398 aa
Domains
PF23171 · Hypoxia-inducible factor 1-alpha bHLH domain PF00989 · PAS fold PF08447 · PAS fold
3D models
8 active PDBs · 8 summary rows
Templates
4ZPK, 4ZPR, 5SY7, 8OSL
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
8 active PDB models 8 summary rows
Region 51-4488 models · 8 summary rows
Actions
Predicted = Low DIMER_sp_Q8IXF0_NPAS3_HUMAN:154:410_8osl_N_1 8osl 154-410 View model · PDB
Predicted = Low DIMER_sp_Q8IXF0_NPAS3_HUMAN:51:447_4zpk_B_1 4zpk 51-447 View model · PDB
Predicted = Low DIMER_sp_Q8IXF0_NPAS3_HUMAN:52:434_4zpr_B_1 4zpr 52-434 View model · PDB
Predicted = Low DIMER_sp_Q8IXF0_NPAS3_HUMAN:52:448_5sy7_B_1 5sy7 52-448 View model · PDB
Predicted = Low TFS_sp_Q8IXF0_NPAS3_HUMAN:154:410_8osl_N_1 8osl 154-410 View model · PDB
Predicted = Low TFS_sp_Q8IXF0_NPAS3_HUMAN:51:447_4zpk_B_1 4zpk 51-447 View model · PDB
Predicted = Low TFS_sp_Q8IXF0_NPAS3_HUMAN:52:434_4zpr_B_1 4zpr 52-434 View model · PDB
Predicted = Low TFS_sp_Q8IXF0_NPAS3_HUMAN:52:448_5sy7_B_1 5sy7 52-448 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 5sy7 51:448 154,52 210,448 P:A,B · DNA:C,D 69.5% / 69.5% 20,100 View · PDB DIMER_sp_Q8IXF0_NPAS3_HUMAN:52:448_5sy7_B_1
1 5sy7 51:448 154,52 210,448 P:A,B · DNA:C,D 69.5% / 69.5% 20,100 View · PDB TFS_sp_Q8IXF0_NPAS3_HUMAN:52:448_5sy7_B_1
3 4zpr 51:448 154,52 210,434 P:A,B · DNA:C,D 34.0% / 49.2% 23,96 View · PDB DIMER_sp_Q8IXF0_NPAS3_HUMAN:52:434_4zpr_B_1
3 4zpr 51:448 154,52 210,434 P:A,B · DNA:C,D 34.0% / 49.2% 23,96 View · PDB TFS_sp_Q8IXF0_NPAS3_HUMAN:52:434_4zpr_B_1
2 4zpk 51:448 154,51 210,447 P:A,B · DNA:C,D 32.0% / 50.4% 21,96 View · PDB DIMER_sp_Q8IXF0_NPAS3_HUMAN:51:447_4zpk_B_1
2 4zpk 51:448 154,51 210,447 P:A,B · DNA:C,D 32.0% / 50.4% 21,96 View · PDB TFS_sp_Q8IXF0_NPAS3_HUMAN:51:447_4zpk_B_1
4 8osl 51:448 154,53 410,101 P:N,P · DNA:I,J 21.3% / 38.8% 67,98 View · PDB DIMER_sp_Q8IXF0_NPAS3_HUMAN:154:410_8osl_N_1
4 8osl 51:448 154,53 410,101 P:N,P · DNA:I,J 21.3% / 38.8% 67,98 View · PDB TFS_sp_Q8IXF0_NPAS3_HUMAN:154:410_8osl_N_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
52-111PF23171Hypoxia-inducible factor 1-alpha bHLH domainoverlaps 51-448
152-212PF00989PAS foldoverlaps 51-448
343-430PF08447PAS foldoverlaps 51-448