ModCRE DB

Transcription factor

Q8IYZ2 - ZNF521

Zinc finger protein 521

Homo sapiens (Human) · Unreviewed (UniProtKB/TrEMBL) · 1346 aa

15 Generated PWM 11 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)5
MotifPredictionSourceDNA bindingSupportLogoActions
M02669_2.00 NN 70-40% CisBP GCACCCCTGGGTGCC 63.9% identity Open · Scan
M10151_2.00 NN 70-40% CisBP GCACCCTTGGGTGC 63.6% identity Open · Scan
MA0116.1 NN 70-40% JASPAR GGCACCCAGGGGTGC 62.4% identity Open · Scan
M00021_2.00 NN 70-40% CisBP TACCCCACAC 50.0% identity Open · Scan
M01397_2.00 NN 70-40% CisBP TGCGGAAT 50.0% identity Open · Scan
ModCRE10
MotifPredictionSourceDNA bindingSupportLogoActions
TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:152:259_5ei9_E_1 ModCRE Homology model GACCCGCCCCCCGCCAA Region 152-259 · 1 3D model Open · Scan
TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:152:263_2i13_A_1 ModCRE Homology model ATTTTCTAGCAGCTTACTGGT Region 152-263 · 1 3D model Open · Scan
TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:153:367_5v3j_E_1 ModCRE Homology model GACCCGGGGTGCCCGGGCAGACCCCC Region 153-367 · 1 3D model Open · Scan
TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:153:367_5v3m_C_1 ModCRE Homology model CGGACAGACCCCCCCGCGGACGGCCG Region 153-367 · 1 3D model Open · Scan
TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:153:367_5wjq_D_1 ModCRE Homology model CCCCCCGGCCTCCCCCGTCAGCCCCCC Region 153-367 · 1 3D model Open · Scan
TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:439:476_6ki6_A_1 ModCRE Homology model AAGATGGGCAA Region 439-476 · 1 3D model Open · Scan
TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:442:495_5k5h_A_1 ModCRE Homology model ACTAAGTTACT Region 442-495 · 1 3D model Open · Scan
TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:442:495_5kkq_A_1 ModCRE Homology model ATTCCGCGCTAGA Region 442-495 · 1 3D model Open · Scan
TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:442:495_5t00_A_1 ModCRE Homology model ATTTACGGCTAGG Region 442-495 · 1 3D model Open · Scan
TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:442:495_5t0u_A_1 ModCRE Homology model CTGCCGAGGCACC Region 442-495 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 1346 aa
152-367
439-495

Region 152-367 5 PWM

Residues
216 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF13912 · C2H2-type zinc finger
3D models
6 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ
Sources
Predicted = Low
Scan this region Show models

Region 439-495 5 PWM

Residues
57 aa
Domains
PF13912 · C2H2-type zinc finger
3D models
5 active PDBs
Templates
5K5H, 5KKQ, 5T00, 5T0U, 6KI6
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
11 active PDB models 6 summary rows
Region 152-3676 models · 6 summary rows
Actions
Predicted = Low DIMER_tr_Q8IYZ2_Q8IYZ2_HUMAN:207:258_1llm_C_1 1llm 207-258 View model · PDB
Predicted = Low TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:152:259_5ei9_E_1 5ei9 152-259 View model · PDB
Predicted = Low TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:152:263_2i13_A_1 2i13 152-263 View model · PDB
Predicted = Low TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:153:367_5v3j_E_1 5v3j 153-367 View model · PDB
Predicted = Low TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:153:367_5v3m_C_1 5v3m 153-367 View model · PDB
Predicted = Low TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:153:367_5wjq_D_1 5wjq 153-367 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
1 1llm 150:370 207,207 258,258 P:C,D · DNA:A,B 44.2% / 53.8% 59,61 View · PDB DIMER_tr_Q8IYZ2_Q8IYZ2_HUMAN:207:258_1llm_C_1
4 2i13 150:370 152 263 P:A · DNA:C,D 41.1% / 56.2% 74 View · PDB TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:152:263_2i13_A_1
5 5ei9 150:370 152 259 P:E · DNA:A,B 39.8% / 55.6% 97 View · PDB TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:152:259_5ei9_E_1
2 5v3m 150:370 153 367 P:C · DNA:A,B 29.5% / 46.3% 74 View · PDB TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:153:367_5v3m_C_1
3 5v3j 150:370 153 367 P:E · DNA:A,B 29.5% / 46.3% 74 View · PDB TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:153:367_5v3j_E_1
1 5wjq 150:370 153 367 P:D · DNA:A,B 29.1% / 45.8% 73 View · PDB TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:153:367_5wjq_D_1
Region 439-4955 models
Actions
Predicted = Low TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:439:476_6ki6_A_1 6ki6 439-476 View model · PDB
Predicted = Low TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:442:495_5k5h_A_1 5k5h 442-495 View model · PDB
Predicted = Low TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:442:495_5kkq_A_1 5kkq 442-495 View model · PDB
Predicted = Low TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:442:495_5t00_A_1 5t00 442-495 View model · PDB
Predicted = Low TFS_tr_Q8IYZ2_Q8IYZ2_HUMAN:442:495_5t0u_A_1 5t0u 442-495 View model · PDB

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
153-175PF00096Zinc finger, C2H2 typeoverlaps 152-367
209-231PF00096Zinc finger, C2H2 typeoverlaps 152-367
347-369PF13912C2H2-type zinc fingeroverlaps 152-367
471-496PF13912C2H2-type zinc fingeroverlaps 439-495
669-693PF13912C2H2-type zinc fingerNo overlap with loaded model regions
700-721PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
729-752PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
965-988PF13912C2H2-type zinc fingerNo overlap with loaded model regions
993-1018PF13912C2H2-type zinc fingerNo overlap with loaded model regions
1291-1314PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions