ModCRE DB

Transcription factor

Q8N7G0 - POU5F2

POU domain, class 5, transcription factor 2 (Sperm 1 POU domain transcription factor) (SPRM-1)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 328 aa

12 Generated PWM 19 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)1
MotifPredictionSourceDNA bindingSupportLogoActions
M08032_2.00 NN 70-40% CisBP CCATTGTTATGCAAA 59.3% identity Open · Scan
ModCRE11
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q8N7G0_PO5F2_HUMAN:118:267_3l1p_A_1 ModCRE Homology model CTTATTTTCCGGGAAAAAAAGG Region 118-267 · 1 3D model Open · Scan
DIMER_sp_Q8N7G0_PO5F2_HUMAN:123:267_1hf0_B_1 ModCRE Homology model CCTTTTTTCAGGTAAAAAAAGG Region 123-267 · 1 3D model Open · Scan
DIMER_sp_Q8N7G0_PO5F2_HUMAN:123:267_5wc9_B_1 ModCRE Homology model AACTTAAAAATTTAAAAAA Region 123-267 · 1 3D model Open · Scan
DIMER_sp_Q8N7G0_PO5F2_HUMAN:124:192_7u0g_L_1 ModCRE Homology model CGTTTTTTTGTTTTGTTATATTTACAGAATAATAAAGAAAAGTATAAAAAAATAAACACAAACAATAAAAAATAAAATTGAAAAATTTTTTCAGGTTCG Region 124-192 · 1 3D model Open · Scan
DIMER_sp_Q8N7G0_PO5F2_HUMAN:124:192_7u0i_M_1 ModCRE Homology model TTTTTGGGGGGATGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATTTTTTCGGGGTAG Region 124-192 · 1 3D model Open · Scan
DIMER_sp_Q8N7G0_PO5F2_HUMAN:211:267_1jgg_B_1 ModCRE Homology model TCGCCCAGGC Region 211-267 · 1 3D model Open · Scan
TFS_sp_Q8N7G0_PO5F2_HUMAN:123:267_1e3o_C_1 ModCRE Homology model ACGATCACCGC Region 123-267 · 1 3D model Open · Scan
TFS_sp_Q8N7G0_PO5F2_HUMAN:123:267_1gt0_C_1 ModCRE Homology model CGTCCCGGAATTGCACG Region 123-267 · 1 3D model Open · Scan
TFS_sp_Q8N7G0_PO5F2_HUMAN:123:267_1hf0_B_1 ModCRE Homology model CGTTTTTTCCCGTAAAAAAAGG Region 123-267 · 1 3D model Open · Scan
TFS_sp_Q8N7G0_PO5F2_HUMAN:123:267_1o4x_A_1 ModCRE Homology model TTTTCGAAAAAAAA Region 123-267 · 1 3D model Open · Scan
TFS_sp_Q8N7G0_PO5F2_HUMAN:125:269_2xsd_C_1 ModCRE Homology model ACTATCAAGG Region 125-269 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 328 aa
118-269

Region 118-269 11 PWM

Residues
152 aa
Domains
PF00157 · Pou domain - N-terminal to homeobox domain PF00046 · Homeodomain
3D models
19 active PDBs · 10 summary rows
Templates
1AU7, 1E3O, 1GT0, 1HF0, 1JGG, 1O4X, 2XSD, 3L1P, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
19 active PDB models 10 summary rows
Region 118-26919 models · 10 summary rows
Actions
Predicted = Low DIMER_sp_Q8N7G0_PO5F2_HUMAN:118:267_3l1p_A_1 3l1p 118-267 View model · PDB
Predicted = Low DIMER_sp_Q8N7G0_PO5F2_HUMAN:123:267_1au7_A_1 1au7 123-267 View model · PDB
Predicted = Low DIMER_sp_Q8N7G0_PO5F2_HUMAN:123:267_1hf0_B_1 1hf0 123-267 View model · PDB
Predicted = Low DIMER_sp_Q8N7G0_PO5F2_HUMAN:123:267_5wc9_B_1 5wc9 123-267 View model · PDB
Predicted = Low DIMER_sp_Q8N7G0_PO5F2_HUMAN:124:192_7u0g_L_1 7u0g 124-192 View model · PDB
Predicted = Low DIMER_sp_Q8N7G0_PO5F2_HUMAN:124:192_7u0i_M_1 7u0i 124-192 View model · PDB
Predicted = Low DIMER_sp_Q8N7G0_PO5F2_HUMAN:124:267_7u0g_K_1 7u0g 124-267 View model · PDB
Predicted = Low DIMER_sp_Q8N7G0_PO5F2_HUMAN:211:267_1jgg_B_1 1jgg 211-267 View model · PDB
Predicted = Low TFS_sp_Q8N7G0_PO5F2_HUMAN:118:267_3l1p_A_1 3l1p 118-267 View model · PDB
Predicted = Low TFS_sp_Q8N7G0_PO5F2_HUMAN:123:267_1au7_A_1 1au7 123-267 View model · PDB
Predicted = Low TFS_sp_Q8N7G0_PO5F2_HUMAN:123:267_1e3o_C_1 1e3o 123-267 View model · PDB
Predicted = Low TFS_sp_Q8N7G0_PO5F2_HUMAN:123:267_1gt0_C_1 1gt0 123-267 View model · PDB
Predicted = Low TFS_sp_Q8N7G0_PO5F2_HUMAN:123:267_1hf0_B_1 1hf0 123-267 View model · PDB
Predicted = Low TFS_sp_Q8N7G0_PO5F2_HUMAN:123:267_1o4x_A_1 1o4x 123-267 View model · PDB
Predicted = Low TFS_sp_Q8N7G0_PO5F2_HUMAN:124:267_7u0g_K_1 7u0g 124-267 View model · PDB
Predicted = Low TFS_sp_Q8N7G0_PO5F2_HUMAN:124:267_8g8b_X_1 8g8b 124-267 View model · PDB
Predicted = Low TFS_sp_Q8N7G0_PO5F2_HUMAN:124:267_8g8e_X_1 8g8e 124-267 View model · PDB
Predicted = Low TFS_sp_Q8N7G0_PO5F2_HUMAN:124:267_8g8g_X_1 8g8g 124-267 View model · PDB
Predicted = Low TFS_sp_Q8N7G0_PO5F2_HUMAN:125:269_2xsd_C_1 2xsd 125-269 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 7u0i 118:277 124,124 192,192 P:L,M · DNA:I,J 69.6% / 85.5% 92,92 View · PDB DIMER_sp_Q8N7G0_PO5F2_HUMAN:124:192_7u0i_M_1
5 7u0g 118:277 124,124 192,192 P:L,M · DNA:I,J 69.6% / 85.5% 92,92 View · PDB DIMER_sp_Q8N7G0_PO5F2_HUMAN:124:192_7u0g_L_1
2 8g8g 118:277 124 267 P:X · DNA:I,J 57.6% / 69.4% 96 View · PDB TFS_sp_Q8N7G0_PO5F2_HUMAN:124:267_8g8g_X_1
3 8g8e 118:277 124 267 P:X · DNA:I,J 57.6% / 69.4% 96 View · PDB TFS_sp_Q8N7G0_PO5F2_HUMAN:124:267_8g8e_X_1
2 7u0g 118:277 124,124 267,192 P:K,M · DNA:I,J 56.9% / 69.4% 97,92 View · PDB DIMER_sp_Q8N7G0_PO5F2_HUMAN:124:267_7u0g_K_1
4 7u0g 118:277 124,124 267,192 P:K,M · DNA:I,J 56.9% / 69.4% 97,92 View · PDB TFS_sp_Q8N7G0_PO5F2_HUMAN:124:267_7u0g_K_1
5 8g8b 118:277 124 267 P:X · DNA:I,J 55.6% / 66.7% 96 View · PDB TFS_sp_Q8N7G0_PO5F2_HUMAN:124:267_8g8b_X_1
1 3l1p 118:277 118,124 267,267 P:A,B · DNA:M,N 54.7% / 69.3% 100,96 View · PDB TFS_sp_Q8N7G0_PO5F2_HUMAN:118:267_3l1p_A_1
1 3l1p 118:277 118,124 267,267 P:A,B · DNA:M,N 54.7% / 69.3% 100,96 View · PIR DIMER_sp_Q8N7G0_PO5F2_HUMAN:118:267_3l1p_A_1
3 1hf0 118:277 123,123 267,267 P:A,B · DNA:M,N 41.8% / 57.5% 99,99 View · PDB DIMER_sp_Q8N7G0_PO5F2_HUMAN:123:267_1hf0_B_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
123-192PF00157Pou domain - N-terminal to homeobox domainoverlaps 118-269
223-261PF00046Homeodomainoverlaps 118-269