ModCRE DB

Transcription factor

Q8N7U7 - TPRX1

Tetra-peptide repeat homeobox protein 1

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 411 aa

73 Generated PWM 12 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)61
MotifPredictionSourceDNA bindingSupportLogoActions
M02162_2.00 NN 70-40% CisBP TTAATTAG 64.7% identity Open · Scan
MA0648.1 NN 70-40% JASPAR GCTAATCCCC 63.6% identity Open · Scan
MA0725.1 NN 70-40% JASPAR CTAATTAT 60.8% identity Open · Scan
MA0662.1 NN 70-40% JASPAR TCTAATTAAC 60.0% identity Open · Scan
MA0886.1 NN 70-40% JASPAR GCTAATTAGC 59.0% identity Open · Scan
MA0644.1 NN 70-40% JASPAR ACCAATTAAC 58.3% identity Open · Scan
M03855_2.00 NN 70-40% CisBP TAATTAGATTA 57.6% identity Open · Scan
M00462_2.00 NN 70-40% CisBP CTAATTG 57.1% identity Open · Scan
M06312_2.00 NN 70-40% CisBP TTAATTA 57.1% identity Open · Scan
MA0889.1 NN 70-40% JASPAR ACTAATTAGC 57.1% identity Open · Scan
MA0890.1 NN 70-40% JASPAR ACCAATTAGC 57.1% identity Open · Scan
M09681_2.00 NN 70-40% CisBP CTAATCCG 56.6% identity Open · Scan
M03814_2.00 NN 70-40% CisBP GTAATGGC 56.5% identity Open · Scan
M03888_2.00 NN 70-40% CisBP GCGTGACGAATC 55.0% identity Open · Scan
M00424_2.00 NN 70-40% CisBP ACTAATTA 54.5% identity Open · Scan
M06545_2.00 NN 70-40% CisBP TTAATTA 54.5% identity Open · Scan
M01241_2.00 NN 70-40% CisBP TTAATCCC 54.1% identity Open · Scan
M06326_2.00 NN 70-40% CisBP TTAATT 54.1% identity Open · Scan
M04929_2.00 NN 70-40% CisBP CTAATCCG 53.8% identity Open · Scan
MA0682.1 NN 70-40% JASPAR TTAATCCC 53.8% identity Open · Scan
MA0682.2 NN 70-40% JASPAR CTAATCCC 53.8% identity Open · Scan
M10806_2.00 NN 70-40% CisBP AATTTTCACGCATGAGTTCAC 53.5% identity Open · Scan
MA0069.1 NN 70-40% JASPAR TTCACGCATGAGTT 53.5% identity Open · Scan
MA0894.1 NN 70-40% JASPAR GCTAATTGGC 53.5% identity Open · Scan
M09208_2.00 NN 70-40% CisBP CCTAATCCTCTTA 52.9% identity Open · Scan
MA0467.1 NN 70-40% JASPAR AAGAGGATTAG 52.9% identity Open · Scan
M06359_2.00 NN 70-40% CisBP TTTAATTA 52.3% identity Open · Scan
M02143_2.00 NN 70-40% CisBP TTAATTGG 52.1% identity Open · Scan
M02209_2.00 NN 70-40% CisBP AGCGGATATA 52.1% identity Open · Scan
M03204_2.00 NN 70-40% CisBP TTAATTGG 52.1% identity Open · Scan
M03828_2.00 NN 70-40% CisBP GTTAATTAACGTTAATTAAC 52.1% identity Open · Scan
M05367_2.00 NN 70-40% CisBP TTAATTAG 52.1% identity Open · Scan
MA0630.1 NN 70-40% JASPAR TTAATTGG 52.1% identity Open · Scan
MA0720.1 NN 70-40% JASPAR CTAATTAA 52.1% identity Open · Scan
M00679_2.00 NN 70-40% CisBP TTAATCCC 52.0% identity Open · Scan
M03121_2.00 NN 70-40% CisBP TTAATTGG 52.0% identity Open · Scan
MA0075.1 NN 70-40% JASPAR AATTA 52.0% identity Open · Scan
MA0075.3 NN 70-40% JASPAR CTAATTAA 52.0% identity Open · Scan
MA0716.1 NN 70-40% JASPAR CTAATTAA 52.0% identity Open · Scan
M09153_2.00 NN 70-40% CisBP GTTAATCCCCT 51.8% identity Open · Scan
MA0712.1 NN 70-40% JASPAR TTAATCCT 51.8% identity Open · Scan
M03903_2.00 NN 70-40% CisBP ATAATTGATTAT 51.7% identity Open · Scan
M00674_2.00 NN 70-40% CisBP TTAATCCC 50.0% identity Open · Scan
M02153_2.00 NN 70-40% CisBP GCCCAATAAA 50.0% identity Open · Scan
M03104_2.00 NN 70-40% CisBP TTAATTACGGTAATTAC 50.0% identity Open · Scan
M03271_2.00 NN 70-40% CisBP GTAATTAC 50.0% identity Open · Scan
M03278_2.00 NN 70-40% CisBP TTAATTTAATTAT 50.0% identity Open · Scan
M03819_2.00 NN 70-40% CisBP TAATCCGTTAATCCG 50.0% identity Open · Scan
M06241_2.00 NN 70-40% CisBP CGTTAATTATTT 50.0% identity Open · Scan
M06548_2.00 NN 70-40% CisBP TTAATTG 50.0% identity Open · Scan
M06554_2.00 NN 70-40% CisBP TTAATTG 50.0% identity Open · Scan
M10741_2.00 NN 70-40% CisBP AACTAATTACCATTATCG 50.0% identity Open · Scan
M10754_2.00 NN 70-40% CisBP CAAGTGCGTG 50.0% identity Open · Scan
MA0706.1 NN 70-40% JASPAR AGTAATTAAC 50.0% identity Open · Scan
MA0715.1 NN 70-40% JASPAR TAATTTAATTA 50.0% identity Open · Scan
MA0854.1 NN 70-40% JASPAR CGAATTAATTAATCACC 50.0% identity Open · Scan
MA0887.1 NN 70-40% JASPAR GGTAATTAGC 50.0% identity Open · Scan
MA0888.1 NN 70-40% JASPAR GGTAATTAGC 50.0% identity Open · Scan
MA0896.1 NN 70-40% JASPAR ACAAGCAATTAATGAAT 50.0% identity Open · Scan
MA0898.1 NN 70-40% JASPAR ACAAGCAATTAAAGAAT 50.0% identity Open · Scan
MA1481.1 NN 70-40% JASPAR CTAATTAC 50.0% identity Open · Scan
ModCRE12
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q8N7U7_TPRX1_HUMAN:2:19_3a01_B_1 ModCRE Homology model AATTAATAAATTTAGCT Region 2-19 · 1 3D model Open · Scan
DIMER_sp_Q8N7U7_TPRX1_HUMAN:2:22_2hdd_A_1 ModCRE Homology model GGAGAAAATTCCTTAG Region 2-22 · 1 3D model Open · Scan
DIMER_sp_Q8N7U7_TPRX1_HUMAN:3:23_1fjl_A_1 ModCRE Homology model ATTAATAATTTTT Region 3-23 · 1 3D model Open · Scan
DIMER_sp_Q8N7U7_TPRX1_HUMAN:4:19_5z2t_C_1 ModCRE Homology model TTAATTTTATTCT Region 4-19 · 1 3D model Open · Scan
DIMER_sp_Q8N7U7_TPRX1_HUMAN:4:19_6dfy_D_1 ModCRE Homology model AGTTATATTTT Region 4-19 · 1 3D model Open · Scan
DIMER_sp_Q8N7U7_TPRX1_HUMAN:9:22_5hod_A_1 ModCRE Homology model GAAATTTTATATATTTTT Region 9-22 · 1 3D model Open · Scan
DIMER_sp_Q8N7U7_TPRX1_HUMAN:9:22_5hod_D_1 ModCRE Homology model GAAATTTTATATATTTTA Region 9-22 · 1 3D model Open · Scan
TFS_sp_Q8N7U7_TPRX1_HUMAN:2:22_1ig7_A_1 ModCRE Homology model CCAAAATTCTCTA Region 2-22 · 1 3D model Open · Scan
TFS_sp_Q8N7U7_TPRX1_HUMAN:2:23_1b8i_A_1 ModCRE Homology model TTAAAGGATTCCT Region 2-23 · 1 3D model Open · Scan
TFS_sp_Q8N7U7_TPRX1_HUMAN:2:23_4cyc_A_1 ModCRE Homology model TCAAAAAATTCTT Region 2-23 · 1 3D model Open · Scan
TFS_sp_Q8N7U7_TPRX1_HUMAN:2:23_4uus_A_1 ModCRE Homology model GGAAAAGATTATC Region 2-23 · 1 3D model Open · Scan
TFS_sp_Q8N7U7_TPRX1_HUMAN:2:25_2r5y_A_1 ModCRE Homology model CAAAGAAATTCCTGG Region 2-25 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 411 aa
2-25

Region 2-25 12 PWM

Residues
24 aa
Domains
No overlapping PFAM annotation recorded
3D models
12 active PDBs · 10 summary rows
Templates
1B8I, 1FJL, 1IG7, 2HDD, 2R5Y, 3A01, 4CYC, 4UUS, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
12 active PDB models 10 summary rows
Region 2-2512 models · 10 summary rows
Actions
Predicted = Low DIMER_sp_Q8N7U7_TPRX1_HUMAN:2:19_3a01_B_1 3a01 2-19 View model · PDB
Predicted = Low DIMER_sp_Q8N7U7_TPRX1_HUMAN:2:22_2hdd_A_1 2hdd 2-22 View model · PDB
Predicted = Low DIMER_sp_Q8N7U7_TPRX1_HUMAN:3:23_1fjl_A_1 1fjl 3-23 View model · PDB
Predicted = Low DIMER_sp_Q8N7U7_TPRX1_HUMAN:4:19_5z2t_C_1 5z2t 4-19 View model · PDB
Predicted = Low DIMER_sp_Q8N7U7_TPRX1_HUMAN:4:19_6dfy_D_1 6dfy 4-19 View model · PDB
Predicted = Low DIMER_sp_Q8N7U7_TPRX1_HUMAN:9:22_5hod_A_1 5hod 9-22 View model · PDB
Predicted = Low DIMER_sp_Q8N7U7_TPRX1_HUMAN:9:22_5hod_D_1 5hod 9-22 View model · PDB
Predicted = Low TFS_sp_Q8N7U7_TPRX1_HUMAN:2:22_1ig7_A_1 1ig7 2-22 View model · PDB
Predicted = Low TFS_sp_Q8N7U7_TPRX1_HUMAN:2:23_1b8i_A_1 1b8i 2-23 View model · PDB
Predicted = Low TFS_sp_Q8N7U7_TPRX1_HUMAN:2:23_4cyc_A_1 4cyc 2-23 View model · PDB
Predicted = Low TFS_sp_Q8N7U7_TPRX1_HUMAN:2:23_4uus_A_1 4uus 2-23 View model · PDB
Predicted = Low TFS_sp_Q8N7U7_TPRX1_HUMAN:2:25_2r5y_A_1 2r5y 2-25 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
2 5hod 1:38 9,9 22,22 P:A,D · DNA:B,C 71.4% / 85.7% 22,24 View · PDB DIMER_sp_Q8N7U7_TPRX1_HUMAN:9:22_5hod_A_1
5 1ig7 1:38 2 22 P:A · DNA:B,C 61.9% / 81.0% 36 View · PDB TFS_sp_Q8N7U7_TPRX1_HUMAN:2:22_1ig7_A_1
3 3a01 1:38 2,2 23,19 P:A,B · DNA:C,D 61.1% / 83.3% 28,31 View · PDB DIMER_sp_Q8N7U7_TPRX1_HUMAN:2:19_3a01_B_1
1 4uus 1:38 2 23 P:A · DNA:C,D 59.1% / 86.4% 32 View · PDB TFS_sp_Q8N7U7_TPRX1_HUMAN:2:23_4uus_A_1
2 1b8i 1:38 2 23 P:A · DNA:C,D 59.1% / 86.4% 35 View · PDB TFS_sp_Q8N7U7_TPRX1_HUMAN:2:23_1b8i_A_1
5 6dfy 1:38 4,4 19,19 P:C,D · DNA:E,F 56.2% / 87.5% 29,30 View · PDB DIMER_sp_Q8N7U7_TPRX1_HUMAN:4:19_6dfy_D_1
3 4cyc 1:38 2 23 P:A · DNA:C,D 54.5% / 81.8% 33 View · PDB TFS_sp_Q8N7U7_TPRX1_HUMAN:2:23_4cyc_A_1
1 1fjl 1:38 3,3 23,20 P:A,B · DNA:D,E 52.4% / 85.7% 32,31 View · PDB DIMER_sp_Q8N7U7_TPRX1_HUMAN:3:23_1fjl_A_1
4 2hdd 1:38 2,2 22,20 P:A,B · DNA:C,D 52.4% / 81.0% 38,33 View · PIR DIMER_sp_Q8N7U7_TPRX1_HUMAN:2:22_2hdd_A_1
4 2r5y 1:38 2 25 P:A · DNA:C,D 50.0% / 79.2% 32 View · PDB TFS_sp_Q8N7U7_TPRX1_HUMAN:2:25_2r5y_A_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Imported domain tags1
Homeobox