Transcription factor

Q8N8C0 - ZNF781

Zinc finger protein 781

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 355 aa

131 Generated PWM 11 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)120

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M04653_2.00	NN 70-40%	CisBP	GGTACGGTTGTCCATGTTGCAA	61.9% identity		Open · Scan
M07707_2.00	NN 70-40%	CisBP	TCCCGC	61.3% identity		Open · Scan
M07689_2.00	NN 70-40%	CisBP	ACCCAGGCTCCTTCCATCTTGTGGCTC	61.0% identity		Open · Scan
M07658_2.00	NN 70-40%	CisBP	CCGCCGCAGCCGCCG	60.8% identity		Open · Scan
M08309_2.00	NN 70-40%	CisBP	AAAAACCCCCCTGCAGAGCCCAGCCCT	60.8% identity		Open · Scan
M08335_2.00	NN 70-40%	CisBP	AGTCGTTGTCTG	60.7% identity		Open · Scan
M07684_2.00	NN 70-40%	CisBP	CCTGTTCTTGACTTT	60.3% identity		Open · Scan
M07635_2.00	NN 70-40%	CisBP	AAGTTTTCTTGTATTATATCT	60.1% identity		Open · Scan
M08944_2.00	NN 70-40%	CisBP	TACCATGCTGTTTTGATTAC	59.8% identity		Open · Scan
M07590_2.00	NN 70-40%	CisBP	TTTTTTTCTTTTATTTTTTTTTTTTTTTTTTTT	59.6% identity		Open · Scan
M07678_2.00	NN 70-40%	CisBP	CCCGCCCCCTCCTCCCCCTTCCCACCC	59.6% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	59.2% identity		Open · Scan
M07700_2.00	NN 70-40%	CisBP	ATGTTGTGAGGAAGCCCA	59.1% identity		Open · Scan
MA1587.1	NN 70-40%	JASPAR	CCTCGACCTCCTGA	59.1% identity		Open · Scan
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	59.0% identity		Open · Scan
M08935_2.00	NN 70-40%	CisBP	CCTCCTCCCTCAGACC	58.7% identity		Open · Scan
M07605_2.00	NN 70-40%	CisBP	TATTTTTTTTTATTTTTTTTTTTTTTTTTT	58.6% identity		Open · Scan
M08267_2.00	NN 70-40%	CisBP	CAGTTTCATTTTCC	58.4% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	58.1% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	57.8% identity		Open · Scan
M08255_2.00	NN 70-40%	CisBP	CTCTTCCGGT	57.5% identity		Open · Scan
M08392_2.00	NN 70-40%	CisBP	CTTCACCTGCTGAGG	57.0% identity		Open · Scan
M08934_2.00	NN 70-40%	CisBP	GCTGTACCTGCTTATTAGGC	57.0% identity		Open · Scan
M08985_2.00	NN 70-40%	CisBP	TGAGGACCTACTGTGTGCC	57.0% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	56.8% identity		Open · Scan
M07729_2.00	NN 70-40%	CisBP	CCAGACTGCCTGCCAAAACCCCCT	56.8% identity		Open · Scan
M07714_2.00	NN 70-40%	CisBP	AGCCCATTGGGGCCTATGCCC	56.6% identity		Open · Scan
M00945_2.00	NN 70-40%	CisBP	CACCGCAC	56.4% identity		Open · Scan
M07598_2.00	NN 70-40%	CisBP	CTGACAATACCAAGTGTTGAC	56.1% identity		Open · Scan
M08386_2.00	NN 70-40%	CisBP	GCCTTAAAAGCTCAGCAC	56.1% identity		Open · Scan
M04650_2.00	NN 70-40%	CisBP	GCATAACTGCCCCGCTGCC	56.0% identity		Open · Scan
M08247_2.00	NN 70-40%	CisBP	AAAAATAACAAACGG	56.0% identity		Open · Scan
MA1592.1	NN 70-40%	JASPAR	GGTATGAGTTCTCGCT	56.0% identity		Open · Scan
MA1594.1	NN 70-40%	JASPAR	AGGGGACATCACTACAGATCCCAC	56.0% identity		Open · Scan
M07712_2.00	NN 70-40%	CisBP	ACATTTTTTTAATCTAAAAAAACATTTACA	55.8% identity		Open · Scan
MA1124.1	NN 70-40%	JASPAR	CATTCATTCATTC	55.8% identity		Open · Scan
M00149_2.00	NN 70-40%	CisBP	CGTACGCC	55.7% identity		Open · Scan
M08252_2.00	NN 70-40%	CisBP	CCGGCTCCAGCACCC	55.7% identity		Open · Scan
M08279_2.00	NN 70-40%	CisBP	CCTCCCTCC	55.7% identity		Open · Scan
M00782_2.00	NN 70-40%	CisBP	AGTGTGCGCTA	55.6% identity		Open · Scan
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	55.6% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	55.6% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	55.6% identity		Open · Scan
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	55.6% identity		Open · Scan
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	55.6% identity		Open · Scan
M08355_2.00	NN 70-40%	CisBP	GCGAACTCCTATTCATCC	55.6% identity		Open · Scan
M08254_2.00	NN 70-40%	CisBP	CTGCCCTGGGACTTT	55.4% identity		Open · Scan
M08256_2.00	NN 70-40%	CisBP	GTGCCTT	55.4% identity		Open · Scan
M07693_2.00	NN 70-40%	CisBP	CTCCTGTGTGTGCCTTGGCTG	55.3% identity		Open · Scan
M07699_2.00	NN 70-40%	CisBP	GGTTTAT	55.3% identity		Open · Scan
M04621_2.00	NN 70-40%	CisBP	AGCAATTCCGCTCA	55.1% identity		Open · Scan
MA1589.1	NN 70-40%	JASPAR	TAGGAGTGGAATTGCTGGGTC	55.1% identity		Open · Scan
MA1602.1	NN 70-40%	JASPAR	CGTCTACACGGG	55.1% identity		Open · Scan
M07581_2.00	NN 70-40%	CisBP	TCCCCTGTGCTTCTCTCCCCT	54.9% identity		Open · Scan
M07649_2.00	NN 70-40%	CisBP	CCCCCCCCCCCCTCAGGAATGCC	54.9% identity		Open · Scan
M07727_2.00	NN 70-40%	CisBP	CGCCGCCTCCCC	54.8% identity		Open · Scan
M08325_2.00	NN 70-40%	CisBP	TTTTTTTTT	54.8% identity		Open · Scan
MA1596.1	NN 70-40%	JASPAR	GCCTCAGCCTCCCGAG	54.8% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	54.7% identity		Open · Scan
M07578_2.00	NN 70-40%	CisBP	CAACTCTCC	54.6% identity		Open · Scan
M07686_2.00	NN 70-40%	CisBP	TAGCTTGTTTCCAGCCAC	54.6% identity		Open · Scan
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	54.5% identity		Open · Scan
M00955_2.00	NN 70-40%	CisBP	ACGTCCTCT	54.5% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	54.5% identity		Open · Scan
M04611_2.00	NN 70-40%	CisBP	CTTTCGGACAC	54.3% identity		Open · Scan
M08917_2.00	NN 70-40%	CisBP	GCTGAGCCATGTGGGGTGCT	54.3% identity		Open · Scan
M07588_2.00	NN 70-40%	CisBP	TCCTTCCCTCTTTCC	54.2% identity		Open · Scan
M07761_2.00	NN 70-40%	CisBP	CTGATTATTCACCCA	54.2% identity		Open · Scan
M08342_2.00	NN 70-40%	CisBP	GCTCTGCCTCCCTCT	53.9% identity		Open · Scan
M08371_2.00	NN 70-40%	CisBP	CCAGACTTGTCCTCT	53.9% identity		Open · Scan
M07607_2.00	NN 70-40%	CisBP	GGCTCCACG	53.7% identity		Open · Scan
MA0528.1	NN 70-40%	JASPAR	GGAGGAGGAGGGGGAGGAGGA	53.7% identity		Open · Scan
M07680_2.00	NN 70-40%	CisBP	AACCCCAAC	53.4% identity		Open · Scan
M07587_2.00	NN 70-40%	CisBP	CCCCCTCCCCAGTCGAGCCCCCGC	53.3% identity		Open · Scan
M07562_2.00	NN 70-40%	CisBP	GAAAAAAAC	53.2% identity		Open · Scan
M08366_2.00	NN 70-40%	CisBP	GTTTGCTGCTTACAA	53.2% identity		Open · Scan
M07582_2.00	NN 70-40%	CisBP	TCCCTG	53.1% identity		Open · Scan
M07579_2.00	NN 70-40%	CisBP	CATCTCCAGGA	53.0% identity		Open · Scan
M08395_2.00	NN 70-40%	CisBP	GCTGCCTACTCTTCC	53.0% identity		Open · Scan
M07770_2.00	NN 70-40%	CisBP	CTTGGACTT	52.9% identity		Open · Scan
M04387_2.00	NN 70-40%	CisBP	CGTGCTCCCC	52.8% identity		Open · Scan
M00786_2.00	NN 70-40%	CisBP	TATATATAT	52.6% identity		Open · Scan
M04536_2.00	NN 70-40%	CisBP	ACGTAACCCGATACC	52.6% identity		Open · Scan
M07593_2.00	NN 70-40%	CisBP	AGATGAAGTCACCCCTCTTAC	52.6% identity		Open · Scan
M07660_2.00	NN 70-40%	CisBP	CCGCGCCTACCTGAGGGCGCGGGCCTGGGG	52.6% identity		Open · Scan
M00134_2.00	NN 70-40%	CisBP	GCCACGCCCA	52.5% identity		Open · Scan
M08914_2.00	NN 70-40%	CisBP	ATTTAGTCCATTTACATTTAATGT	52.4% identity		Open · Scan
M08373_2.00	NN 70-40%	CisBP	CCCCCTGGCTCTTCCTCT	52.3% identity		Open · Scan
M08300_2.00	NN 70-40%	CisBP	CTGCCCAATTCAT	52.2% identity		Open · Scan
M08358_2.00	NN 70-40%	CisBP	CCCTCCCCCTCC	52.2% identity		Open · Scan
M07667_2.00	NN 70-40%	CisBP	CCGCACAGGCCCCCGGGCCCC	52.1% identity		Open · Scan
MA1600.1	NN 70-40%	JASPAR	ATACAGTCCACCCCTTTA	52.1% identity		Open · Scan
M08367_2.00	NN 70-40%	CisBP	GGGGTGATGACCACTCTGGCTTCTTAC	51.8% identity		Open · Scan
M07610_2.00	NN 70-40%	CisBP	CCTTCTTCCTCCCCCCTGCCCACC	51.7% identity		Open · Scan
M04598_2.00	NN 70-40%	CisBP	CGCTAACTCTCCACA	51.4% identity		Open · Scan
M08311_2.00	NN 70-40%	CisBP	CTGGAACAGAAGGGGCGA	51.3% identity		Open · Scan
MA0056.1	NN 70-40%	JASPAR	TGGGGA	51.3% identity		Open · Scan
M01538_2.00	NN 70-40%	CisBP	GCCCCTGA	51.2% identity		Open · Scan
M05853_2.00	NN 70-40%	CisBP	CCACCTTTAGCCATATCT	51.0% identity		Open · Scan
M07683_2.00	NN 70-40%	CisBP	GTGGGAAAGCCT	50.9% identity		Open · Scan
MA1154.1	NN 70-40%	JASPAR	CTTTCCCACAACACGAC	50.9% identity		Open · Scan
MA1601.1	NN 70-40%	JASPAR	ATGTGGGAAA	50.9% identity		Open · Scan
M04613_2.00	NN 70-40%	CisBP	CTCATGTGCTAATTACAAA	50.8% identity		Open · Scan
M07601_2.00	NN 70-40%	CisBP	CAGATGCCGGCACCATGCTTC	50.8% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	50.8% identity		Open · Scan
M07753_2.00	NN 70-40%	CisBP	TGCATTCCTTGGCTTGTG	50.6% identity		Open · Scan
M00250_2.00	NN 70-40%	CisBP	AATGCTAACT	50.5% identity		Open · Scan
M07717_2.00	NN 70-40%	CisBP	GGCTCCGCCCCC	50.4% identity		Open · Scan
M08390_2.00	NN 70-40%	CisBP	GCTTTGTTGACTCAC	50.4% identity		Open · Scan
MA1652.1	NN 70-40%	JASPAR	GGAGGAGGTGAGAA	50.4% identity		Open · Scan
MA1656.1	NN 70-40%	JASPAR	CCAAGCCCAACCAG	50.4% identity		Open · Scan
M00132_2.00	NN 70-40%	CisBP	TGCTACCGTT	50.0% identity		Open · Scan
M01039_2.00	NN 70-40%	CisBP	CCCCCTA	50.0% identity		Open · Scan
M01174_2.00	NN 70-40%	CisBP	GCTACCGT	50.0% identity		Open · Scan
M06169_2.00	NN 70-40%	CisBP	GCCACGCCCAAC	50.0% identity		Open · Scan
M07750_2.00	NN 70-40%	CisBP	CTTCTGACACCA	50.0% identity		Open · Scan
M08860_2.00	NN 70-40%	CisBP	TCTTATAAGGGCACTAATCCCATT	50.0% identity		Open · Scan
M08908_2.00	NN 70-40%	CisBP	GCTGCTGCTTCTGCTG	50.0% identity		Open · Scan
MA1517.1	NN 70-40%	JASPAR	GGCCACGCCCA	50.0% identity		Open · Scan
MA1542.1	NN 70-40%	JASPAR	TGCTACTGTT	50.0% identity		Open · Scan

ModCRE11

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
DIMER_sp_Q8N8C0_ZN781_HUMAN:31:70_1llm_D_1	ModCRE	Homology model	CCCGGCGCCGGG	Region 31-70 · 1 3D model		Open · Scan
TFS_sp_Q8N8C0_ZN781_HUMAN:15:132_5v3j_E_1	ModCRE	Homology model	ACAAAGGGCACGGCGGCCCCCG	Region 15-132 · 1 3D model		Open · Scan
TFS_sp_Q8N8C0_ZN781_HUMAN:15:132_5v3m_C_1	ModCRE	Homology model	AAAAAAGGCACCCCGCGCCCCC	Region 15-132 · 1 3D model		Open · Scan
TFS_sp_Q8N8C0_ZN781_HUMAN:19:132_5wjq_D_1	ModCRE	Homology model	CCTCACGGCCGGGCTCTCC	Region 19-132 · 1 3D model		Open · Scan
TFS_sp_Q8N8C0_ZN781_HUMAN:20:127_2i13_A_1	ModCRE	Homology model	AGGCCAGGGGCTTAGAAAGT	Region 20-127 · 1 3D model		Open · Scan
TFS_sp_Q8N8C0_ZN781_HUMAN:29:111_4r2q_A_1	ModCRE	Homology model	GGCGGGGCGA	Region 29-111 · 1 3D model		Open · Scan
TFS_sp_Q8N8C0_ZN781_HUMAN:29:111_4r2r_A_1	ModCRE	Homology model	GGGGGGGTGG	Region 29-111 · 1 3D model		Open · Scan
TFS_sp_Q8N8C0_ZN781_HUMAN:29:111_5kl5_A_1	ModCRE	Homology model	GGGGGGGCGG	Region 29-111 · 1 3D model		Open · Scan
TFS_sp_Q8N8C0_ZN781_HUMAN:30:133_5ei9_E_1	ModCRE	Homology model	TGCCACCCCCCCCACC	Region 30-133 · 1 3D model		Open · Scan
TFS_sp_Q8N8C0_ZN781_HUMAN:31:111_5kl3_A_1	ModCRE	Homology model	GCGGGGCGGG	Region 31-111 · 1 3D model		Open · Scan
TFS_sp_Q8N8C0_ZN781_HUMAN:33:112_2kmk_A_1	ModCRE	Homology model	AGCGGGGTGTGGGGGC	Region 33-112 · 1 3D model		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 355 aa

15-133

Region 15-133 11 PWM

Residues

119 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

11 active PDBs · 6 summary rows

Templates

1LLM, 2I13, 2KMK, 4R2Q, 4R2R, 5EI9, 5KL3, 5KL5, ...

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

11 active PDB models 6 summary rows

Region 15-13311 models · 6 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_sp_Q8N8C0_ZN781_HUMAN:31:70_1llm_D_1	1llm	31-70	View model · PDB
Predicted = Low	TFS_sp_Q8N8C0_ZN781_HUMAN:15:132_5v3j_E_1	5v3j	15-132	View model · PDB
Predicted = Low	TFS_sp_Q8N8C0_ZN781_HUMAN:15:132_5v3m_C_1	5v3m	15-132	View model · PDB
Predicted = Low	TFS_sp_Q8N8C0_ZN781_HUMAN:19:132_5wjq_D_1	5wjq	19-132	View model · PDB
Predicted = Low	TFS_sp_Q8N8C0_ZN781_HUMAN:20:127_2i13_A_1	2i13	20-127	View model · PDB
Predicted = Low	TFS_sp_Q8N8C0_ZN781_HUMAN:29:111_4r2q_A_1	4r2q	29-111	View model · PDB
Predicted = Low	TFS_sp_Q8N8C0_ZN781_HUMAN:29:111_4r2r_A_1	4r2r	29-111	View model · PDB
Predicted = Low	TFS_sp_Q8N8C0_ZN781_HUMAN:29:111_5kl5_A_1	5kl5	29-111	View model · PDB
Predicted = Low	TFS_sp_Q8N8C0_ZN781_HUMAN:30:133_5ei9_E_1	5ei9	30-133	View model · PDB
Predicted = Low	TFS_sp_Q8N8C0_ZN781_HUMAN:31:111_5kl3_A_1	5kl3	31-111	View model · PDB
Predicted = Low	TFS_sp_Q8N8C0_ZN781_HUMAN:33:112_2kmk_A_1	2kmk	33-112	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
1	2i13	15:133	20	127	P:A · DNA:C,D	56.5% / 70.4%	71	View · PDB TFS_sp_Q8N8C0_ZN781_HUMAN:20:127_2i13_A_1
2	5wjq	15:133	19	132	P:D · DNA:A,B	54.4% / 71.1%	40	View · PDB TFS_sp_Q8N8C0_ZN781_HUMAN:19:132_5wjq_D_1
5	5ei9	15:133	30	133	P:E · DNA:A,B	51.9% / 72.1%	93	View · PDB TFS_sp_Q8N8C0_ZN781_HUMAN:30:133_5ei9_E_1
1	1llm	15:133	31,31	70,70	P:C,D · DNA:A,B	50.0% / 67.5%	45,47	View · PDB DIMER_sp_Q8N8C0_ZN781_HUMAN:31:70_1llm_D_1
3	5v3m	15:133	15	132	P:C · DNA:A,B	49.2% / 70.3%	42	View · PDB TFS_sp_Q8N8C0_ZN781_HUMAN:15:132_5v3m_C_1
4	5v3j	15:133	15	132	P:E · DNA:A,B	49.2% / 70.3%	42	View · PDB TFS_sp_Q8N8C0_ZN781_HUMAN:15:132_5v3j_E_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
33-55	PF00096	Zinc finger, C2H2 type	overlaps 15-133
61-83	PF00096	Zinc finger, C2H2 type	overlaps 15-133
89-111	PF00096	Zinc finger, C2H2 type	overlaps 15-133