ModCRE DB

Transcription factor

Q8NCK3 - ZNF485

Zinc finger protein 485

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 441 aa

89 Generated PWM 6 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known1
MotifPredictionSourceDNA bindingSupportLogoActions
M07741_2.00 Known CisBP ACATATCCCCATTCC Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)82
MotifPredictionSourceDNA bindingSupportLogoActions
M00955_2.00 NN 70-40% CisBP ACGTCCTCT 61.1% identity Open · Scan
M00939_2.00 NN 70-40% CisBP CCACCTCA 58.8% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 58.8% identity Open · Scan
M08375_2.00 NN 70-40% CisBP TTCCCCATTGGCTACTGCACCGGTCCT 57.8% identity Open · Scan
M02924_2.00 NN 70-40% CisBP AGTGTTAACAGAACACCT 57.1% identity Open · Scan
M08267_2.00 NN 70-40% CisBP CAGTTTCATTTTCC 57.1% identity Open · Scan
M08325_2.00 NN 70-40% CisBP TTTTTTTTT 57.1% identity Open · Scan
MA1602.1 NN 70-40% JASPAR CGTCTACACGGG 57.0% identity Open · Scan
M08985_2.00 NN 70-40% CisBP TGAGGACCTACTGTGTGCC 56.8% identity Open · Scan
MA1124.1 NN 70-40% JASPAR CATTCATTCATTC 56.8% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 56.4% identity Open · Scan
M07579_2.00 NN 70-40% CisBP CATCTCCAGGA 56.2% identity Open · Scan
M08355_2.00 NN 70-40% CisBP GCGAACTCCTATTCATCC 56.2% identity Open · Scan
M00782_2.00 NN 70-40% CisBP AGTGTGCGCTA 56.1% identity Open · Scan
M04598_2.00 NN 70-40% CisBP CGCTAACTCTCCACA 56.0% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 55.9% identity Open · Scan
M04650_2.00 NN 70-40% CisBP GCATAACTGCCCCGCTGCC 55.9% identity Open · Scan
M00134_2.00 NN 70-40% CisBP GCCACGCCCA 55.7% identity Open · Scan
M08949_2.00 NN 70-40% CisBP TTCTATTTCTTCTTGTGTCA 55.6% identity Open · Scan
M08254_2.00 NN 70-40% CisBP CTGCCCTGGGACTTT 55.4% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 55.2% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 55.2% identity Open · Scan
M00950_2.00 NN 70-40% CisBP GCAGCCCA 55.2% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 55.2% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 55.2% identity Open · Scan
M07753_2.00 NN 70-40% CisBP TGCATTCCTTGGCTTGTG 55.2% identity Open · Scan
M04613_2.00 NN 70-40% CisBP CTCATGTGCTAATTACAAA 55.0% identity Open · Scan
M08901_2.00 NN 70-40% CisBP CCAGTTCACACC 55.0% identity Open · Scan
M07683_2.00 NN 70-40% CisBP GTGGGAAAGCCT 54.6% identity Open · Scan
MA1601.1 NN 70-40% JASPAR ATGTGGGAAA 54.6% identity Open · Scan
M00609_2.00 NN 70-40% CisBP GGAAGCCCTA 54.1% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 54.1% identity Open · Scan
M08245_2.00 NN 70-40% CisBP TGGTGCCTTATTCCC 53.8% identity Open · Scan
M04387_2.00 NN 70-40% CisBP CGTGCTCCCC 53.7% identity Open · Scan
M08908_2.00 NN 70-40% CisBP GCTGCTGCTTCTGCTG 53.6% identity Open · Scan
M07581_2.00 NN 70-40% CisBP TCCCCTGTGCTTCTCTCCCCT 53.5% identity Open · Scan
M08334_2.00 NN 70-40% CisBP TTTGTTTTTTTCTGATTGCTTTTTACTTAT 53.5% identity Open · Scan
M07649_2.00 NN 70-40% CisBP CCCCCCCCCCCCTCAGGAATGCC 53.4% identity Open · Scan
M07638_2.00 NN 70-40% CisBP TGCAGCTCCCTGCCC 53.3% identity Open · Scan
M07678_2.00 NN 70-40% CisBP CCCGCCCCCTCCTCCCCCTTCCCACCC 53.0% identity Open · Scan
M06108_2.00 NN 70-40% CisBP ACAACAACAAC 52.7% identity Open · Scan
M00142_2.00 NN 70-40% CisBP GTGCTCCT 52.6% identity Open · Scan
M04463_2.00 NN 70-40% CisBP CACCACGCCCA 52.6% identity Open · Scan
MA0039.1 NN 70-40% JASPAR TAAAGGAAGG 52.6% identity Open · Scan
MA0039.3 NN 70-40% JASPAR CCACACCCTGC 52.6% identity Open · Scan
MA1515.1 NN 70-40% JASPAR CACCACGCCCA 52.6% identity Open · Scan
M04515_2.00 NN 70-40% CisBP TATGCTATAACAAGCAGCCCC 52.5% identity Open · Scan
M07587_2.00 NN 70-40% CisBP CCCCCTCCCCAGTCGAGCCCCCGC 52.5% identity Open · Scan
M08329_2.00 NN 70-40% CisBP GCTGCATAGTATTCC 52.5% identity Open · Scan
M08314_2.00 NN 70-40% CisBP ATTCATCAAGGTCCTCAACAATGG 52.4% identity Open · Scan
M07610_2.00 NN 70-40% CisBP CCTTCTTCCTCCCCCCTGCCCACC 52.2% identity Open · Scan
M08263_2.00 NN 70-40% CisBP ATCTCGGCACTTTGGGAGGCCA 52.2% identity Open · Scan
M05844_2.00 NN 70-40% CisBP TCACCTGT 52.0% identity Open · Scan
MA0103.1 NN 70-40% JASPAR CACCTG 52.0% identity Open · Scan
MA0103.2 NN 70-40% JASPAR CCTCACCTG 52.0% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 51.7% identity Open · Scan
M07605_2.00 NN 70-40% CisBP TATTTTTTTTTATTTTTTTTTTTTTTTTTT 51.7% identity Open · Scan
M08335_2.00 NN 70-40% CisBP AGTCGTTGTCTG 51.7% identity Open · Scan
M07588_2.00 NN 70-40% CisBP TCCTTCCCTCTTTCC 51.5% identity Open · Scan
M07657_2.00 NN 70-40% CisBP CCCCTGCATGTCCCCATTTTT 51.5% identity Open · Scan
M08283_2.00 NN 70-40% CisBP GACTTTTATTTT 51.5% identity Open · Scan
M07562_2.00 NN 70-40% CisBP GAAAAAAAC 51.4% identity Open · Scan
M08292_2.00 NN 70-40% CisBP TGTATTCCTTGTCATGTGTGG 51.4% identity Open · Scan
M00224_2.00 NN 70-40% CisBP CCCGCCCC 51.3% identity Open · Scan
MA1517.1 NN 70-40% JASPAR GGCCACGCCCA 51.3% identity Open · Scan
M04621_2.00 NN 70-40% CisBP AGCAATTCCGCTCA 51.1% identity Open · Scan
M08247_2.00 NN 70-40% CisBP AAAAATAACAAACGG 51.1% identity Open · Scan
MA1588.1 NN 70-40% JASPAR GAATTCTTGGTTGAC 51.1% identity Open · Scan
M00786_2.00 NN 70-40% CisBP TATATATAT 51.0% identity Open · Scan
M01044_2.00 NN 70-40% CisBP TCTCTCTTTC 50.8% identity Open · Scan
M03671_2.00 NN 70-40% CisBP ATTACCATACAAGTGCAC 50.8% identity Open · Scan
M00217_2.00 NN 70-40% CisBP TTACTCAATAT 50.7% identity Open · Scan
M07723_2.00 NN 70-40% CisBP CCGCTGCTCCCTGCT 50.7% identity Open · Scan
M04536_2.00 NN 70-40% CisBP ACGTAACCCGATACC 50.5% identity Open · Scan
M08395_2.00 NN 70-40% CisBP GCTGCCTACTCTTCC 50.5% identity Open · Scan
M08934_2.00 NN 70-40% CisBP GCTGTACCTGCTTATTAGGC 50.3% identity Open · Scan
MA1656.1 NN 70-40% JASPAR CCAAGCCCAACCAG 50.2% identity Open · Scan
M07712_2.00 NN 70-40% CisBP ACATTTTTTTAATCTAAAAAAACATTTACA 50.1% identity Open · Scan
M04465_2.00 NN 70-40% CisBP GTGATTCTTATCTTATCCTT 50.0% identity Open · Scan
M06179_2.00 NN 70-40% CisBP TAAGCCTATAGA 50.0% identity Open · Scan
M07727_2.00 NN 70-40% CisBP CGCCGCCTCCCC 50.0% identity Open · Scan
M09008_2.00 NN 70-40% CisBP CCCGGCCCCACCCT 50.0% identity Open · Scan
ModCRE6
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q8NCK3_ZN485_HUMAN:380:433_1llm_D_1 ModCRE Homology model TTTGGGCCCAAA Region 380-433 · 1 3D model Open · Scan
TFS_sp_Q8NCK3_ZN485_HUMAN:154:432_5wjq_D_1 ModCRE Homology model GCGCCCACCCCGGTGGCCCCCCCCCCCC Region 154-432 · 1 3D model Open · Scan
TFS_sp_Q8NCK3_ZN485_HUMAN:157:432_5v3j_E_1 ModCRE Homology model GCCCCCGGGGCCCCCCCCCCCGCGGC Region 157-432 · 1 3D model Open · Scan
TFS_sp_Q8NCK3_ZN485_HUMAN:157:432_5v3m_C_1 ModCRE Homology model GGGGCCACGCCCCCCCCCCCCCGGGC Region 157-432 · 1 3D model Open · Scan
TFS_sp_Q8NCK3_ZN485_HUMAN:159:430_7w1m_H_1 ModCRE Homology model AATTTGGACCGGGAGCCAGGGACGAAACAAAATCCGGGCCTA Region 159-430 · 1 3D model Open · Scan
TFS_sp_Q8NCK3_ZN485_HUMAN:279:432_2i13_A_1 ModCRE Homology model ACCCCTAGACTACTACTGAAA Region 279-432 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 441 aa
154-433

Region 154-433 6 PWM

Residues
280 aa
Domains
PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
6 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 5V3J, 5V3M, 5WJQ, 7W1M
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
6 active PDB models 6 summary rows
Region 154-4336 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_Q8NCK3_ZN485_HUMAN:380:433_1llm_D_1 1llm 380-433 View model · PDB
Predicted = Low TFS_sp_Q8NCK3_ZN485_HUMAN:154:432_5wjq_D_1 5wjq 154-432 View model · PDB
Predicted = Low TFS_sp_Q8NCK3_ZN485_HUMAN:157:432_5v3j_E_1 5v3j 157-432 View model · PDB
Predicted = Low TFS_sp_Q8NCK3_ZN485_HUMAN:157:432_5v3m_C_1 5v3m 157-432 View model · PDB
Predicted = Low TFS_sp_Q8NCK3_ZN485_HUMAN:159:430_7w1m_H_1 7w1m 159-430 View model · PDB
Predicted = Low TFS_sp_Q8NCK3_ZN485_HUMAN:279:432_2i13_A_1 2i13 279-432 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
4 2i13 154:436 279 432 P:A · DNA:C,D 53.9% / 66.9% 100 View · PDB TFS_sp_Q8NCK3_ZN485_HUMAN:279:432_2i13_A_1
2 5v3m 154:436 157 432 P:C · DNA:A,B 52.2% / 68.8% 99 View · PDB TFS_sp_Q8NCK3_ZN485_HUMAN:157:432_5v3m_C_1
3 5v3j 154:436 157 432 P:E · DNA:A,B 52.2% / 68.8% 99 View · PDB TFS_sp_Q8NCK3_ZN485_HUMAN:157:432_5v3j_E_1
1 5wjq 154:436 154 432 P:D · DNA:A,B 52.0% / 69.9% 99 View · PDB TFS_sp_Q8NCK3_ZN485_HUMAN:154:432_5wjq_D_1
1 1llm 154:436 380,380 433,433 P:C,D · DNA:A,B 44.4% / 61.1% 62,63 View · PDB DIMER_sp_Q8NCK3_ZN485_HUMAN:380:433_1llm_D_1
5 7w1m 154:436 159 430 P:H · DNA:F,G 35.0% / 51.3% 84 View · PDB TFS_sp_Q8NCK3_ZN485_HUMAN:159:430_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
10-51PF01352KRAB boxNo overlap with loaded model regions
130-152PF00096Zinc finger, C2H2 typeNo overlap with loaded model regions
158-180PF00096Zinc finger, C2H2 typeoverlaps 154-433
242-264PF00096Zinc finger, C2H2 typeoverlaps 154-433
270-292PF00096Zinc finger, C2H2 typeoverlaps 154-433
298-320PF00096Zinc finger, C2H2 typeoverlaps 154-433
326-348PF00096Zinc finger, C2H2 typeoverlaps 154-433
354-376PF00096Zinc finger, C2H2 typeoverlaps 154-433
382-404PF00096Zinc finger, C2H2 typeoverlaps 154-433
410-432PF00096Zinc finger, C2H2 typeoverlaps 154-433