Transcription factor

Q8TAF7 - ZNF461

Zinc finger protein 461 (Gonadotropin-inducible ovary transcription repressor 1) (GIOT-1)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 563 aa

88 Generated PWM 14 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)75

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
M00939_2.00	NN 70-40%	CisBP	CCACCTCA	69.4% identity		Open · Scan
M04653_2.00	NN 70-40%	CisBP	GGTACGGTTGTCCATGTTGCAA	66.1% identity		Open · Scan
M00955_2.00	NN 70-40%	CisBP	ACGTCCTCT	65.8% identity		Open · Scan
M04613_2.00	NN 70-40%	CisBP	CTCATGTGCTAATTACAAA	63.7% identity		Open · Scan
M07613_2.00	NN 70-40%	CisBP	TCACTCAGTCATTCA	63.2% identity		Open · Scan
M00952_2.00	NN 70-40%	CisBP	GGATGCTC	62.3% identity		Open · Scan
M00960_2.00	NN 70-40%	CisBP	TGCATCCC	62.3% identity		Open · Scan
M04650_2.00	NN 70-40%	CisBP	GCATAACTGCCCCGCTGCC	62.2% identity		Open · Scan
M02924_2.00	NN 70-40%	CisBP	AGTGTTAACAGAACACCT	61.7% identity		Open · Scan
MA1124.1	NN 70-40%	JASPAR	CATTCATTCATTC	61.4% identity		Open · Scan
M00944_2.00	NN 70-40%	CisBP	TCGCTATAA	61.1% identity		Open · Scan
M00948_2.00	NN 70-40%	CisBP	GCAGCACC	61.1% identity		Open · Scan
M00950_2.00	NN 70-40%	CisBP	GCAGCCCA	61.1% identity		Open · Scan
M00953_2.00	NN 70-40%	CisBP	ATCTATAT	61.1% identity		Open · Scan
M00958_2.00	NN 70-40%	CisBP	CGGCATCCC	61.1% identity		Open · Scan
M00959_2.00	NN 70-40%	CisBP	GCCCTCCC	61.1% identity		Open · Scan
M00943_2.00	NN 70-40%	CisBP	CCCGCTGC	60.0% identity		Open · Scan
M04621_2.00	NN 70-40%	CisBP	AGCAATTCCGCTCA	60.0% identity		Open · Scan
M08355_2.00	NN 70-40%	CisBP	GCGAACTCCTATTCATCC	58.9% identity		Open · Scan
M08247_2.00	NN 70-40%	CisBP	AAAAATAACAAACGG	58.8% identity		Open · Scan
M04598_2.00	NN 70-40%	CisBP	CGCTAACTCTCCACA	58.2% identity		Open · Scan
M08325_2.00	NN 70-40%	CisBP	TTTTTTTTT	58.0% identity		Open · Scan
M08375_2.00	NN 70-40%	CisBP	TTCCCCATTGGCTACTGCACCGGTCCT	57.7% identity		Open · Scan
M08267_2.00	NN 70-40%	CisBP	CAGTTTCATTTTCC	57.4% identity		Open · Scan
M08254_2.00	NN 70-40%	CisBP	CTGCCCTGGGACTTT	56.8% identity		Open · Scan
M00782_2.00	NN 70-40%	CisBP	AGTGTGCGCTA	56.4% identity		Open · Scan
M04465_2.00	NN 70-40%	CisBP	GTGATTCTTATCTTATCCTT	56.4% identity		Open · Scan
M08392_2.00	NN 70-40%	CisBP	CTTCACCTGCTGAGG	56.0% identity		Open · Scan
M08329_2.00	NN 70-40%	CisBP	GCTGCATAGTATTCC	55.8% identity		Open · Scan
M04611_2.00	NN 70-40%	CisBP	CTTTCGGACAC	55.1% identity		Open · Scan
M07702_2.00	NN 70-40%	CisBP	CTTCTTCCTTGG	55.1% identity		Open · Scan
M08334_2.00	NN 70-40%	CisBP	TTTGTTTTTTTCTGATTGCTTTTTACTTAT	55.1% identity		Open · Scan
M04387_2.00	NN 70-40%	CisBP	CGTGCTCCCC	54.9% identity		Open · Scan
M08887_2.00	NN 70-40%	CisBP	CCTCCTCCAGGAAGCCTTCCCTGA	54.8% identity		Open · Scan
M07648_2.00	NN 70-40%	CisBP	GCTTGCAAAAAAAATTTAACTCCCAGCTC	54.7% identity		Open · Scan
M04536_2.00	NN 70-40%	CisBP	ACGTAACCCGATACC	54.6% identity		Open · Scan
M05844_2.00	NN 70-40%	CisBP	TCACCTGT	54.6% identity		Open · Scan
MA0103.1	NN 70-40%	JASPAR	CACCTG	54.6% identity		Open · Scan
MA0103.2	NN 70-40%	JASPAR	CCTCACCTG	54.6% identity		Open · Scan
M07700_2.00	NN 70-40%	CisBP	ATGTTGTGAGGAAGCCCA	54.5% identity		Open · Scan
M07633_2.00	NN 70-40%	CisBP	CTCTCGTTGTGCCTTTGCCAT	54.2% identity		Open · Scan
M08292_2.00	NN 70-40%	CisBP	TGTATTCCTTGTCATGTGTGG	54.2% identity		Open · Scan
M08373_2.00	NN 70-40%	CisBP	CCCCCTGGCTCTTCCTCT	54.2% identity		Open · Scan
MA1656.1	NN 70-40%	JASPAR	CCAAGCCCAACCAG	54.2% identity		Open · Scan
M00786_2.00	NN 70-40%	CisBP	TATATATAT	54.1% identity		Open · Scan
M00945_2.00	NN 70-40%	CisBP	CACCGCAC	54.0% identity		Open · Scan
M07600_2.00	NN 70-40%	CisBP	GCATTAGC	54.0% identity		Open · Scan
M07656_2.00	NN 70-40%	CisBP	TGTCTAGTAAGTCTA	53.9% identity		Open · Scan
M07649_2.00	NN 70-40%	CisBP	CCCCCCCCCCCCTCAGGAATGCC	53.7% identity		Open · Scan
M07581_2.00	NN 70-40%	CisBP	TCCCCTGTGCTTCTCTCCCCT	52.9% identity		Open · Scan
M07753_2.00	NN 70-40%	CisBP	TGCATTCCTTGGCTTGTG	52.4% identity		Open · Scan
M08274_2.00	NN 70-40%	CisBP	TTACTTGCAGCCCAACGCATTCCTAAC	52.4% identity		Open · Scan
M07578_2.00	NN 70-40%	CisBP	CAACTCTCC	52.2% identity		Open · Scan
M07691_2.00	NN 70-40%	CisBP	CCTGCAGCCACCTTGGCCTTG	52.1% identity		Open · Scan
M05853_2.00	NN 70-40%	CisBP	CCACCTTTAGCCATATCT	51.9% identity		Open · Scan
M07689_2.00	NN 70-40%	CisBP	ACCCAGGCTCCTTCCATCTTGTGGCTC	51.9% identity		Open · Scan
M07712_2.00	NN 70-40%	CisBP	ACATTTTTTTAATCTAAAAAAACATTTACA	51.7% identity		Open · Scan
M08395_2.00	NN 70-40%	CisBP	GCTGCCTACTCTTCC	51.7% identity		Open · Scan
M08335_2.00	NN 70-40%	CisBP	AGTCGTTGTCTG	51.6% identity		Open · Scan
M07628_2.00	NN 70-40%	CisBP	AGTGGTTCTGCTTCT	51.5% identity		Open · Scan
M07587_2.00	NN 70-40%	CisBP	CCCCCTCCCCAGTCGAGCCCCCGC	51.3% identity		Open · Scan
M07777_2.00	NN 70-40%	CisBP	GCCAATTTCCGTGGTGTAAAT	51.2% identity		Open · Scan
M00142_2.00	NN 70-40%	CisBP	GTGCTCCT	51.0% identity		Open · Scan
M01456_2.00	NN 70-40%	CisBP	GTGATCGGCG	50.9% identity		Open · Scan
M08367_2.00	NN 70-40%	CisBP	GGGGTGATGACCACTCTGGCTTCTTAC	50.9% identity		Open · Scan
M08901_2.00	NN 70-40%	CisBP	CCAGTTCACACC	50.6% identity		Open · Scan
M00609_2.00	NN 70-40%	CisBP	GGAAGCCCTA	50.4% identity		Open · Scan
M08366_2.00	NN 70-40%	CisBP	GTTTGCTGCTTACAA	50.4% identity		Open · Scan
MA1602.1	NN 70-40%	JASPAR	CGTCTACACGGG	50.4% identity		Open · Scan
M07588_2.00	NN 70-40%	CisBP	TCCTTCCCTCTTTCC	50.2% identity		Open · Scan
M07729_2.00	NN 70-40%	CisBP	CCAGACTGCCTGCCAAAACCCCCT	50.1% identity		Open · Scan
M08859_2.00	NN 70-40%	CisBP	CATTTTTTCCTCCTAGGCCT	50.1% identity		Open · Scan
M03671_2.00	NN 70-40%	CisBP	ATTACCATACAAGTGCAC	50.0% identity		Open · Scan
M07658_2.00	NN 70-40%	CisBP	CCGCCGCAGCCGCCG	50.0% identity		Open · Scan
MA0516.1	NN 70-40%	JASPAR	GCCCCGCCCCCTCCC	50.0% identity		Open · Scan

ModCRE13

Motif	Prediction	Source	DNA binding	Support	Logo	Actions
DIMER_sp_Q8TAF7_ZN461_HUMAN:355:406_1llm_D_1	ModCRE	Homology model	TCCGGCGCCGGA	Region 355-406 · 1 3D model		Open · Scan
TFS_sp_Q8TAF7_ZN461_HUMAN:174:244_5wjq_D_1	ModCRE	Homology model	AAAACTATCAGATAGGAA	Region 174-244 · 1 3D model		Open · Scan
TFS_sp_Q8TAF7_ZN461_HUMAN:174:269_5v3j_E_1	ModCRE	Homology model	AACGACATATTAGATGCGGA	Region 174-269 · 1 3D model		Open · Scan
TFS_sp_Q8TAF7_ZN461_HUMAN:174:269_5v3m_C_1	ModCRE	Homology model	AGGGATTCTAATTATGGGAA	Region 174-269 · 1 3D model		Open · Scan
TFS_sp_Q8TAF7_ZN461_HUMAN:174:269_5wjq_D_1	ModCRE	Homology model	AGGTGATTGTAGCCCTTCAAA	Region 174-269 · 1 3D model		Open · Scan
TFS_sp_Q8TAF7_ZN461_HUMAN:176:267_2i13_A_1	ModCRE	Homology model	CGCGGCTAAAAGAGATC	Region 176-267 · 1 3D model		Open · Scan
TFS_sp_Q8TAF7_ZN461_HUMAN:178:267_5ei9_E_1	ModCRE	Homology model	AAGGGATGGGGGCCCAA	Region 178-267 · 1 3D model		Open · Scan
TFS_sp_Q8TAF7_ZN461_HUMAN:183:244_5v3j_E_1	ModCRE	Homology model	GTTAAAATAATT	Region 183-244 · 1 3D model		Open · Scan
TFS_sp_Q8TAF7_ZN461_HUMAN:183:244_5v3m_C_1	ModCRE	Homology model	GTAAAAATTTATT	Region 183-244 · 1 3D model		Open · Scan
TFS_sp_Q8TAF7_ZN461_HUMAN:246:520_5v3j_E_1	ModCRE	Homology model	TCCACCCCGTTTTCCCCCCCCGGGGG	Region 246-520 · 1 3D model		Open · Scan
TFS_sp_Q8TAF7_ZN461_HUMAN:246:520_5v3m_C_1	ModCRE	Homology model	CCAGGCCAACTCGACTTCCACGGGCC	Region 246-520 · 1 3D model		Open · Scan
TFS_sp_Q8TAF7_ZN461_HUMAN:270:545_5wjq_D_1	ModCRE	Homology model	TCATGGCCCCTCGCCATCACACCCGGCG	Region 270-545 · 1 3D model		Open · Scan
TFS_sp_Q8TAF7_ZN461_HUMAN:366:519_2i13_A_1	ModCRE	Homology model	TTTTAAGGCCTCCTTCTTCAT	Region 366-519 · 1 3D model		Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 563 aa

174-545

Region 174-545 13 PWM

Residues

372 aa

Domains

PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type

3D models

14 active PDBs · 6 summary rows

Templates

1LLM, 2I13, 5EI9, 5V3J, 5V3M, 5WJQ, 7W1M

Sources

Predicted = Low

Scan this region Show models

3D Models

Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.

14 active PDB models 6 summary rows

Region 174-54514 models · 6 summary rows

Source ↕	Model ↕	Template ↕	Residues modeled ↕	Actions
Predicted = Low	DIMER_sp_Q8TAF7_ZN461_HUMAN:355:406_1llm_D_1	1llm	355-406	View model · PDB
Predicted = Low	TFS_sp_Q8TAF7_ZN461_HUMAN:174:244_5wjq_D_1	5wjq	174-244	View model · PDB
Predicted = Low	TFS_sp_Q8TAF7_ZN461_HUMAN:174:269_5v3j_E_1	5v3j	174-269	View model · PDB
Predicted = Low	TFS_sp_Q8TAF7_ZN461_HUMAN:174:269_5v3m_C_1	5v3m	174-269	View model · PDB
Predicted = Low	TFS_sp_Q8TAF7_ZN461_HUMAN:174:269_5wjq_D_1	5wjq	174-269	View model · PDB
Predicted = Low	TFS_sp_Q8TAF7_ZN461_HUMAN:176:267_2i13_A_1	2i13	176-267	View model · PDB
Predicted = Low	TFS_sp_Q8TAF7_ZN461_HUMAN:178:267_5ei9_E_1	5ei9	178-267	View model · PDB
Predicted = Low	TFS_sp_Q8TAF7_ZN461_HUMAN:183:244_5v3j_E_1	5v3j	183-244	View model · PDB
Predicted = Low	TFS_sp_Q8TAF7_ZN461_HUMAN:183:244_5v3m_C_1	5v3m	183-244	View model · PDB
Predicted = Low	TFS_sp_Q8TAF7_ZN461_HUMAN:246:520_5v3j_E_1	5v3j	246-520	View model · PDB
Predicted = Low	TFS_sp_Q8TAF7_ZN461_HUMAN:246:520_5v3m_C_1	5v3m	246-520	View model · PDB
Predicted = Low	TFS_sp_Q8TAF7_ZN461_HUMAN:262:515_7w1m_H_1	7w1m	262-515	View model · PDB
Predicted = Low	TFS_sp_Q8TAF7_ZN461_HUMAN:270:545_5wjq_D_1	5wjq	270-545	View model · PDB
Predicted = Low	TFS_sp_Q8TAF7_ZN461_HUMAN:366:519_2i13_A_1	2i13	366-519	View model · PDB

Model-summary evidence imported for this region.

Rank	Template	Domain	N-tails	C-tails	Chains	Identity / similarity	Coverage	Model file
2	5v3m	246:545	246	520	P:C · DNA:A,B	55.8% / 71.7%	99	View · PDB TFS_sp_Q8TAF7_ZN461_HUMAN:246:520_5v3m_C_1
3	5v3j	246:545	246	520	P:E · DNA:A,B	55.8% / 71.7%	99	View · PDB TFS_sp_Q8TAF7_ZN461_HUMAN:246:520_5v3j_E_1
4	2i13	246:545	366	519	P:A · DNA:C,D	55.8% / 68.2%	100	View · PDB TFS_sp_Q8TAF7_ZN461_HUMAN:366:519_2i13_A_1
1	5wjq	246:545	270	545	P:D · DNA:A,B	55.6% / 70.6%	98	View · PDB TFS_sp_Q8TAF7_ZN461_HUMAN:270:545_5wjq_D_1
1	1llm	246:545	355,355	406,406	P:C,D · DNA:A,B	42.3% / 57.7%	59,61	View · PDB DIMER_sp_Q8TAF7_ZN461_HUMAN:355:406_1llm_D_1
5	7w1m	246:545	262	515	P:H · DNA:F,G	35.1% / 49.8%	78	View · PDB TFS_sp_Q8TAF7_ZN461_HUMAN:262:515_7w1m_H_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

Residues	PFAM	Domain	Used by prediction region?
5-46	PF01352	KRAB box	No overlap with loaded model regions
273-295	PF00096	Zinc finger, C2H2 type	overlaps 174-545
301-323	PF00096	Zinc finger, C2H2 type	overlaps 174-545
329-351	PF00096	Zinc finger, C2H2 type	overlaps 174-545
357-379	PF00096	Zinc finger, C2H2 type	overlaps 174-545
385-407	PF00096	Zinc finger, C2H2 type	overlaps 174-545
413-435	PF00096	Zinc finger, C2H2 type	overlaps 174-545
441-463	PF00096	Zinc finger, C2H2 type	overlaps 174-545
469-491	PF00096	Zinc finger, C2H2 type	overlaps 174-545
497-519	PF00096	Zinc finger, C2H2 type	overlaps 174-545