ModCRE DB

Transcription factor

Q8TD17 - ZNF398

Zinc finger protein 398 (Zinc finger DNA-binding protein p52/p71)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 642 aa

29 Generated PWM 9 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known1
MotifPredictionSourceDNA bindingSupportLogoActions
M07716_2.00 Known CisBP CTCCCTCCCTCCCT Direct PWM Open · Scan
Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)19
MotifPredictionSourceDNA bindingSupportLogoActions
M00950_2.00 NN 70-40% CisBP GCAGCCCA 54.7% identity Open · Scan
M00960_2.00 NN 70-40% CisBP TGCATCCC 54.7% identity Open · Scan
M00943_2.00 NN 70-40% CisBP CCCGCTGC 53.5% identity Open · Scan
M00944_2.00 NN 70-40% CisBP TCGCTATAA 53.5% identity Open · Scan
M00948_2.00 NN 70-40% CisBP GCAGCACC 53.5% identity Open · Scan
M00953_2.00 NN 70-40% CisBP ATCTATAT 53.5% identity Open · Scan
M00958_2.00 NN 70-40% CisBP CGGCATCCC 53.5% identity Open · Scan
M00959_2.00 NN 70-40% CisBP GCCCTCCC 53.5% identity Open · Scan
M01538_2.00 NN 70-40% CisBP GCCCCTGA 53.4% identity Open · Scan
M08358_2.00 NN 70-40% CisBP CCCTCCCCCTCC 53.0% identity Open · Scan
M01442_2.00 NN 70-40% CisBP ACCCCACATT 52.5% identity Open · Scan
M00952_2.00 NN 70-40% CisBP GGATGCTC 52.3% identity Open · Scan
M04611_2.00 NN 70-40% CisBP CTTTCGGACAC 52.0% identity Open · Scan
M01447_2.00 NN 70-40% CisBP TACCCCTGA 51.7% identity Open · Scan
M01441_2.00 NN 70-40% CisBP CCCCTGAATT 50.0% identity Open · Scan
M02903_2.00 NN 70-40% CisBP ATGCCACGCCCCTTTTTG 50.0% identity Open · Scan
M06179_2.00 NN 70-40% CisBP TAAGCCTATAGA 50.0% identity Open · Scan
M08525_2.00 NN 70-40% CisBP CCCCGCA 50.0% identity Open · Scan
M08540_2.00 NN 70-40% CisBP CCCCT 50.0% identity Open · Scan
ModCRE9
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q8TD17_ZN398_HUMAN:509:560_1llm_D_1 ModCRE Homology model CTGCGCGCGAAG Region 509-560 · 1 3D model Open · Scan
TFS_sp_Q8TD17_ZN398_HUMAN:340:587_5wjq_D_1 ModCRE Homology model GGGGGGCCGGGCCGGGGGGTGCGGGGGG Region 340-587 · 1 3D model Open · Scan
TFS_sp_Q8TD17_ZN398_HUMAN:345:592_5v3j_E_1 ModCRE Homology model AGAGACCCCCCCGGTGGGTTCCG Region 345-592 · 1 3D model Open · Scan
TFS_sp_Q8TD17_ZN398_HUMAN:345:592_5v3m_C_1 ModCRE Homology model GGGGGGGGGGGCTTGGACCTGGAG Region 345-592 · 1 3D model Open · Scan
TFS_sp_Q8TD17_ZN398_HUMAN:436:588_2i13_A_1 ModCRE Homology model TATCAGCTAGCGGGCTATAAC Region 436-588 · 1 3D model Open · Scan
TFS_sp_Q8TD17_ZN398_HUMAN:450:561_2jpa_A_1 ModCRE Homology model CCAGCGGCGGGCCC Region 450-561 · 1 3D model Open · Scan
TFS_sp_Q8TD17_ZN398_HUMAN:452:562_5egb_A_1 ModCRE Homology model CCCCCGGCCGGGGGCCGG Region 452-562 · 1 3D model Open · Scan
TFS_sp_Q8TD17_ZN398_HUMAN:452:562_5ei9_E_1 ModCRE Homology model GCCCCGGGCCGGGGCCCC Region 452-562 · 1 3D model Open · Scan
TFS_sp_Q8TD17_ZN398_HUMAN:454:562_5eh2_F_1 ModCRE Homology model CCCCCGGGGGGGGGCCGGA Region 454-562 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 642 aa
340-592

Region 340-592 9 PWM

Residues
253 aa
Domains
PF13913 · zinc-finger of a C2HC-type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type PF00096 · Zinc finger, C2H2 type
3D models
9 active PDBs · 6 summary rows
Templates
1LLM, 2I13, 2JPA, 5EGB, 5EH2, 5EI9, 5V3J, 5V3M, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
9 active PDB models 6 summary rows
Region 340-5929 models · 6 summary rows
Actions
Predicted = Low DIMER_sp_Q8TD17_ZN398_HUMAN:509:560_1llm_D_1 1llm 509-560 View model · PDB
Predicted = Low TFS_sp_Q8TD17_ZN398_HUMAN:340:587_5wjq_D_1 5wjq 340-587 View model · PDB
Predicted = Low TFS_sp_Q8TD17_ZN398_HUMAN:345:592_5v3j_E_1 5v3j 345-592 View model · PDB
Predicted = Low TFS_sp_Q8TD17_ZN398_HUMAN:345:592_5v3m_C_1 5v3m 345-592 View model · PDB
Predicted = Low TFS_sp_Q8TD17_ZN398_HUMAN:436:588_2i13_A_1 2i13 436-588 View model · PDB
Predicted = Low TFS_sp_Q8TD17_ZN398_HUMAN:450:561_2jpa_A_1 2jpa 450-561 View model · PDB
Predicted = Low TFS_sp_Q8TD17_ZN398_HUMAN:452:562_5egb_A_1 5egb 452-562 View model · PDB
Predicted = Low TFS_sp_Q8TD17_ZN398_HUMAN:452:562_5ei9_E_1 5ei9 452-562 View model · PDB
Predicted = Low TFS_sp_Q8TD17_ZN398_HUMAN:454:562_5eh2_F_1 5eh2 454-562 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
5 5ei9 340:598 452 562 P:E · DNA:A,B 51.4% / 67.6% 100 View · PDB TFS_sp_Q8TD17_ZN398_HUMAN:452:562_5ei9_E_1
4 2i13 340:598 436 588 P:A · DNA:C,D 48.4% / 64.1% 99 View · PDB TFS_sp_Q8TD17_ZN398_HUMAN:436:588_2i13_A_1
1 1llm 340:598 509,509 560,560 P:C,D · DNA:A,B 42.3% / 61.5% 59,61 View · PDB DIMER_sp_Q8TD17_ZN398_HUMAN:509:560_1llm_D_1
2 5v3m 340:598 345 592 P:C · DNA:A,B 40.2% / 52.2% 88 View · PDB TFS_sp_Q8TD17_ZN398_HUMAN:345:592_5v3m_C_1
3 5v3j 340:598 345 592 P:E · DNA:A,B 40.2% / 52.2% 88 View · PDB TFS_sp_Q8TD17_ZN398_HUMAN:345:592_5v3j_E_1
1 5wjq 340:598 340 587 P:D · DNA:A,B 38.2% / 53.4% 87 View · PDB TFS_sp_Q8TD17_ZN398_HUMAN:340:587_5wjq_D_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
142-183PF01352KRAB boxNo overlap with loaded model regions
399-419PF13913zinc-finger of a C2HC-typeoverlaps 340-592
427-449PF00096Zinc finger, C2H2 typeoverlaps 340-592
455-477PF00096Zinc finger, C2H2 typeoverlaps 340-592
483-505PF00096Zinc finger, C2H2 typeoverlaps 340-592
511-533PF00096Zinc finger, C2H2 typeoverlaps 340-592
539-561PF00096Zinc finger, C2H2 typeoverlaps 340-592
567-590PF00096Zinc finger, C2H2 typeoverlaps 340-592