ModCRE DB

Transcription factor

Q8WYA1 - BMAL2

Basic helix-loop-helix ARNT-like protein 2 (Aryl hydrocarbon receptor nuclear translocator-like protein 2) (Basic-helix-loop-helix-PAS protein MOP9) (Brain and muscle ARNT-like 2) (CYCLE-like factor) (CLIF) (Class E basic helix-loop-helix protein 6) (bHLHe6) (Member of PAS protein 9) (PAS domain-containing protein 9)

Homo sapiens (Human) · Reviewed (UniProtKB/Swiss-Prot) · 636 aa

9 Generated PWM 18 3D models

Motif Prediction

Only entries with a generated matrix are shown here.

Known0

No generated PWM in this category.

Nearest Neighbor (>70%)0

No generated PWM in this category.

Nearest Neighbor (70% - 40%)3
MotifPredictionSourceDNA bindingSupportLogoActions
M04125_2.00 NN 70-40% CisBP GTCACATGAC 52.5% identity Open · Scan
M09478_2.00 NN 70-40% CisBP CACGTGAC 52.3% identity Open · Scan
M03615_2.00 NN 70-40% CisBP GTCACGTGAC 51.3% identity Open · Scan
ModCRE6
MotifPredictionSourceDNA bindingSupportLogoActions
DIMER_sp_Q8WYA1_BMAL2_HUMAN:104:162_4h10_A_1 ModCRE Homology model TGCGCACGTGTGCC Region 104-162 · 1 3D model Open · Scan
DIMER_sp_Q8WYA1_BMAL2_HUMAN:109:163_1mdy_B_1 ModCRE Homology model GAAACACGTGGCTA Region 109-163 · 1 3D model Open · Scan
TFS_sp_Q8WYA1_BMAL2_HUMAN:104:162_4h10_A_1 ModCRE Homology model TGCACACGTGGCCC Region 104-162 · 1 3D model Open · Scan
TFS_sp_Q8WYA1_BMAL2_HUMAN:104:287_5v0l_A_1 ModCRE Homology model TGACTGGCTCT Region 104-287 · 1 3D model Open · Scan
TFS_sp_Q8WYA1_BMAL2_HUMAN:109:161_4atk_B_1 ModCRE Homology model CCATCCATGGGGGCCC Region 109-161 · 1 3D model Open · Scan
TFS_sp_Q8WYA1_BMAL2_HUMAN:109:470_5sy7_A_1 ModCRE Homology model CGCGACGTTACGTCACAC Region 109-470 · 1 3D model Open · Scan

Model-supported DNA-binding regions

Protein residue intervals where structure models support predicted PWMs. Domain annotations and modeled regions are shown together when available.

1 636 aa
104-472

Region 104-472 6 PWM

Residues
369 aa
Domains
PF00010 · Helix-loop-helix DNA-binding domain PF00989 · PAS fold PF14598 · PAS domain
3D models
18 active PDBs · 10 summary rows
Templates
1AM9, 1MDY, 4ATK, 4H10, 4ZPK, 5SY7, 5V0L, 7XI3, ...
Sources
Predicted = Low
Scan this region Show models
3D Models
Collapsible technical table. Rows are grouped by protein region and retain model, template, residue coverage, and available summary evidence.
18 active PDB models 10 summary rows
Region 104-47218 models · 10 summary rows
Actions
Predicted = Low DIMER_sp_Q8WYA1_BMAL2_HUMAN:104:162_4h10_A_1 4h10 104-162 View model · PDB
Predicted = Low DIMER_sp_Q8WYA1_BMAL2_HUMAN:104:472_7xi4_A_1 7xi4 104-472 View model · PDB
Predicted = Low DIMER_sp_Q8WYA1_BMAL2_HUMAN:104:472_8osl_N_1 8osl 104-472 View model · PDB
Predicted = Low DIMER_sp_Q8WYA1_BMAL2_HUMAN:109:161_1am9_B_1 1am9 109-161 View model · PDB
Predicted = Low DIMER_sp_Q8WYA1_BMAL2_HUMAN:109:161_1am9_D_1 1am9 109-161 View model · PDB
Predicted = Low DIMER_sp_Q8WYA1_BMAL2_HUMAN:109:163_1mdy_B_1 1mdy 109-163 View model · PDB
Predicted = Low DIMER_sp_Q8WYA1_BMAL2_HUMAN:109:470_5sy7_A_1 5sy7 109-470 View model · PDB
Predicted = Low DIMER_sp_Q8WYA1_BMAL2_HUMAN:109:472_4zpk_A_1 4zpk 109-472 View model · PDB
Predicted = Low DIMER_sp_Q8WYA1_BMAL2_HUMAN:109:472_8osk_N_1 8osk 109-472 View model · PDB
Predicted = Low TFS_sp_Q8WYA1_BMAL2_HUMAN:104:162_4h10_A_1 4h10 104-162 View model · PDB
Predicted = Low TFS_sp_Q8WYA1_BMAL2_HUMAN:104:287_5v0l_A_1 5v0l 104-287 View model · PDB
Predicted = Low TFS_sp_Q8WYA1_BMAL2_HUMAN:104:472_7xi4_A_1 7xi4 104-472 View model · PDB
Predicted = Low TFS_sp_Q8WYA1_BMAL2_HUMAN:104:472_8osl_N_1 8osl 104-472 View model · PDB
Predicted = Low TFS_sp_Q8WYA1_BMAL2_HUMAN:106:472_7xi3_A_1 7xi3 106-472 View model · PDB
Predicted = Low TFS_sp_Q8WYA1_BMAL2_HUMAN:109:161_4atk_B_1 4atk 109-161 View model · PDB
Predicted = Low TFS_sp_Q8WYA1_BMAL2_HUMAN:109:470_5sy7_A_1 5sy7 109-470 View model · PDB
Predicted = Low TFS_sp_Q8WYA1_BMAL2_HUMAN:109:472_4zpk_A_1 4zpk 109-472 View model · PDB
Predicted = Low TFS_sp_Q8WYA1_BMAL2_HUMAN:109:472_8osk_N_1 8osk 109-472 View model · PDB

Model-summary evidence imported for this region.

RankTemplateDomainN-tailsC-tailsChainsIdentity / similarityCoverageModel file
2 8osk 104:472 104,109 472,472 P:M,N · DNA:I,J 54.5% / 66.5% 96,98 View · PDB TFS_sp_Q8WYA1_BMAL2_HUMAN:109:472_8osk_N_1
2 8osk 104:472 104,109 472,472 P:M,N · DNA:I,J 54.5% / 66.5% 96,98 View · PDB DIMER_sp_Q8WYA1_BMAL2_HUMAN:109:472_8osk_N_1
1 8osl 104:472 104,109 472,157 P:N,P · DNA:I,J 54.0% / 66.4% 98,98 View · PDB TFS_sp_Q8WYA1_BMAL2_HUMAN:104:472_8osl_N_1
1 8osl 104:472 104,109 472,157 P:N,P · DNA:I,J 54.0% / 66.4% 98,98 View · PDB DIMER_sp_Q8WYA1_BMAL2_HUMAN:104:472_8osl_N_1
3 7xi4 104:472 104,117 472,244 P:A,B · DNA:C,D 36.7% / 52.8% 98,40 View · PDB TFS_sp_Q8WYA1_BMAL2_HUMAN:104:472_7xi4_A_1
3 7xi4 104:472 104,117 472,244 P:A,B · DNA:C,D 36.7% / 52.8% 98,40 View · PDB DIMER_sp_Q8WYA1_BMAL2_HUMAN:104:472_7xi4_A_1
5 5sy7 104:472 109,186 470,243 P:A,B · DNA:C,D 35.8% / 50.8% 97,20 View · PDB DIMER_sp_Q8WYA1_BMAL2_HUMAN:109:470_5sy7_A_1
4 4zpk 104:472 109,109 472,469 P:A,B · DNA:C,D 35.6% / 50.8% 97,91 View · PDB DIMER_sp_Q8WYA1_BMAL2_HUMAN:109:472_4zpk_A_1
5 4zpk 104:472 109,109 472,469 P:A,B · DNA:C,D 35.6% / 50.8% 97,91 View · PDB TFS_sp_Q8WYA1_BMAL2_HUMAN:109:472_4zpk_A_1
4 7xi3 104:472 106 472 P:A · DNA:C,D 34.6% / 53.6% 97 View · PDB TFS_sp_Q8WYA1_BMAL2_HUMAN:106:472_7xi3_A_1

View full model evidence table for rank, chains, N/C tails, coverage, RMSD-template information, identity/similarity, and linked model files.

Domains

Annotated protein domains. Overlaps with model-supported DNA-binding regions are shown when available.

ResiduesPFAMDomainUsed by prediction region?
109-161PF00010Helix-loop-helix DNA-binding domainoverlaps 104-472
183-244PF00989PAS foldoverlaps 104-472
370-472PF14598PAS domainoverlaps 104-472